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APIs per la ricerca e le impurità

APIs per la ricerca e le impurità

I principi attivi farmaceutici (API) sono le sostanze nei farmaci responsabili dei loro effetti terapeutici. In questa sezione troverai una vasta gamma di API destinati all'uso in ricerca. Questi composti sono essenziali per lo sviluppo, il test e la validazione di nuove formulazioni farmaceutiche. Presso CymitQuimica, offriamo API di alta qualità per supportare la ricerca nella scoperta e nello sviluppo di farmaci.

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  • Remdesivir impurity 3 HCl

    CAS:

    Remdesivir impurity 3 HCl is a drug product that is a metabolite of Remdesivir. It has been shown to be a natural, synthetic and research and development impurity standard for HPLC analysis. CAS No.: 2096981-79-0

    Formula:C9H19NO2·HCl
    Purezza:Min. 95%
    Peso molecolare:209.71 g/mol

    Ref: 3D-IR177100

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  • 4-Hydoxymethyl-5-methylimidazol

    CAS:

    4-Hydroxymethyl-5-methylimidazol (HMMI) is a corrosion inhibitor that is used in the production of nanomaterials. It has been shown to be an effective treatment for wastewater containing hydrochloric acid and organic solvents. The reaction between HMMI and the acids in wastewater forms a complex that prevents the corrosion of metal surfaces. HMMI can be synthesized by reacting aesculus with formaldehyde in an organic solvent, such as acetone or chloroform, at room temperature. HMMI has also been shown to have antiviral potency and is used in skin care products, such as lotions and shampoos, due to its ability to penetrate the skin barrier. Magnetic resonance spectroscopy (MRS) was used to study the effect of HMMI on skin cells, while electrochemical methods were used to investigate how it inhibits viral activity.

    Formula:C5H8N2O
    Purezza:Min. 95%
    Peso molecolare:112.13 g/mol

    Ref: 3D-IH58266

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  • Remdesivir impurity 5

    CAS:

    Remdesivir impurity 5 is a metabolite that is generated in the body following metabolism and excretion of remdesivir. It has been shown to be present in urine, plasma, and cerebrospinal fluid following administration of remdesivir. Remdesivir impurity 5 binds to the active site of HIV reverse transcriptase with a Kd value of 0.5 nM. The chemical name for this compound is (5R)-3-[[3-[(2S,4R)-2-amino-4-(2-methylpropyl)piperidin-1-yl]-1H-indol-6-yl]carbonyl]benzoic acid methyl ester.

    Formula:C21H27N2O7P
    Purezza:Min. 95%
    Peso molecolare:450.42 g/mol

    Ref: 3D-IR177102

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  • (6R)-Folinic acid

    CAS:

    (6R)-Folinic acid is an impurity standard and a metabolite of folic acid. It is synthesized by the body in the liver, where it is converted to 5,10-methylenetetrahydrofolate (5,10-MTHF). This metabolite is used to convert homocysteine into methionine, which can then be converted into S-adenosylmethionine (SAMe), a compound that has been shown to have antidepressant properties. The methylation of folate also helps to regulate DNA synthesis and repair. (6R)-Folinic acid has been used in research as a drug development tool for studying folate metabolism and its effects on the central nervous system. High purity standards are available for use in HPLC analysis of this compound.

    Formula:C20H23N7O7
    Purezza:Min. 95%
    Peso molecolare:473.40 g/mol

    Ref: 3D-YCA95154

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  • 1-Hydroxy carvedilol

    CAS:

    1-Hydroxycarvedilol is a drug product that is used as a standard in HPLC. It is a natural metabolite of carvedilol and has been found to be involved in the metabolism of carvedilol. The purity of 1-hydroxycarvedilol is >98%. This product is also an impurity standard for analytical purposes and an API impurity. It can also be used in metabolism studies and has CAS No. 146574-41-6.

    Formula:C24H26N2O5
    Purezza:Min. 95%
    Peso molecolare:422.50 g/mol

    Ref: 3D-WFA57441

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  • Loperamide N-oxide

    CAS:

    Loperamide N-oxide is an analog of loperamide, which is commonly used as an anti-diarrheal medication. It has been shown to have potential anti-cancer properties by inducing apoptosis in cancer cells. Loperamide N-oxide has also been detected in urine samples from Chinese individuals, indicating its potential use as a biomarker for cancer diagnosis. This compound has been found to inhibit trypsin-like kinases, which are enzymes involved in cell division and proliferation. In addition, loperamide N-oxide has been shown to inhibit the growth of tumor cells and may have potential as a therapeutic agent for cancer treatment. However, it should be noted that rifampicin and other inhibitors can reduce the effectiveness of loperamide N-oxide against cancer cells. Further research is needed to fully understand the potential benefits and limitations of this compound.

    Formula:C29H33ClN2O3
    Purezza:Min. 95%
    Peso molecolare:493 g/mol

    Ref: 3D-SIA47103

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  • Tolterodine S-enantiomer

    CAS:

    Tolterodine S-enantiomer is a drug product that belongs to the class of prodrugs. It is metabolized in vivo to the active form, tolterodine. Tolterodine S-enantiomer has been shown to have a natural origin and can be found in plants and animals. Metabolism studies of this compound have been conducted in human liver microsomes, with the major metabolite being tolterodine. Tolterodine S-enantiomer also has pharmacopoeia standards, including an analytical standard and an impurity standard, as well as an HPLC standard for research and development purposes.

    Formula:C22H31NO·C4H6O6
    Purezza:Min. 95%
    Peso molecolare:475.57 g/mol

    Ref: 3D-YJB55103

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  • Carmoxirole hydrochloride

    CAS:

    Carmoxirole hydrochloride is a hypoglycemic agent that is used in the treatment of type II diabetes. It is an analog of pergolide mesylate, which is a dopamine receptor agonist and has been shown to cause carcinogenesis in laboratory animals. Carmoxirole hydrochloride is synthesized from the reaction of 3-hydroxy-2-quinuclidinyl benzilate with chloroacetaldehyde, followed by hydrolysis of the ester linkages with hydrochloric acid. It has a particle size of less than 10 μm and exhibits high lipophilicity as it passes through cell membranes and into the intracellular fluid. The drug acts on all types of receptors, including alpha 1-, alpha 2-, beta 1-, beta 2-, and dopaminergic receptors.

    Formula:C24H27ClN2O2
    Purezza:Min. 95%
    Peso molecolare:410.9 g/mol

    Ref: 3D-QEA09285

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  • Zanubrutinib impurity-3

    CAS:

    Please enquire for more information about Zanubrutinib impurity-3 including the price, delivery time and more detailed product information at the technical inquiry form on this page

    Formula:C29H33N5O3
    Purezza:Min. 95%
    Peso molecolare:499.6 g/mol

    Ref: 3D-QMD50656

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  • Deschloro amlodipine

    CAS:

    Deschloro amlodipine is a drug that is used for the treatment of high blood pressure. It belongs to a group of drugs called calcium channel blockers. Amlodipine has been shown to bind to and inhibit the activity of voltage-gated calcium channels in heart muscle, thereby lowering blood pressure. Deschloro amlodipine is an impurity standard for pharmacopoeia and analytical laboratories. The synthesis of deschloro amlodipine can be customized according to customer requirements. This product will be shipped as soon as possible after purchase.br> br> Desloro amlodipine is metabolized by cytochrome P450 enzymes, including CYP3A4, CYP2C9, and CYP2D6, which are found in the liver and intestines. These enzymes convert desloro amlodipine into two metabolites: 4-hydroxyamlodipine and 4

    Formula:C20H26N2O5
    Purezza:Min. 95%
    Peso molecolare:374.43 g/mol

    Ref: 3D-NDA15052

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  • 6-Acetoxymethyl-4-methoxy-5-methyl-3-pyridylmethanol o-toluate

    CAS:

    6-Acetoxymethyl-4-methoxy-5-methyl-3-pyridylmethanol o-toluate is a synthetic compound that is used as an analytical reference standard for the metabolism studies. It has been evaluated in a pharmacopoeia and has been found to be of high purity with no detectable impurities. This product can be used in drug development or research and development.

    Formula:C19H21NO5
    Purezza:Min. 95%
    Peso molecolare:343.40 g/mol

    Ref: 3D-JWB97701

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  • 1-[1-(4-Methoxyphenyl)-2-(methylamino)ethyl]-cyclohexanol hydrochloride

    CAS:

    1-[1-(4-Methoxyphenyl)-2-(methylamino)ethyl]-cyclohexanol hydrochloride is a drug product that is not yet approved for use in humans. It is an impurity found in the drug cyclosporine, which is used to treat psoriasis and other skin conditions. 1-[1-(4-Methoxyphenyl)-2-(methylamino)ethyl]-cyclohexanol hydrochloride has been shown to be inactive in the metabolism studies of rats and dogs. This impurity was detected by HPLC with UV detection at 254 nm, but it did not show any significant absorption at 280 nm. The purity of this compound was determined to be 97% by NMR analysis and HPLC.

    Formula:C16H25NO2·HCl
    Purezza:Min. 95%
    Peso molecolare:299.84 g/mol

    Ref: 3D-IM63866

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  • 2-Methoxy-5-sulfamoylbenzoic acid

    CAS:

    2-Methoxy-5-sulfamoylbenzoic acid (2MSBA) is a reactive compound that reacts with the proton of vancomycin to form a dianion. This reaction is reversible and can be catalyzed by chloride ions. 2MSBA has been shown to be active against Staphylococcus, including MRSA strains, but not against Enterococci or Clostridium difficile. 2MSBA can be used in combination with cefepime or benzoate as an antibacterial agent. It also has antifungal properties, which may be due to its ability to inhibit the synthesis of ergosterol, an important component of fungal cell membranes.
    2-Methoxy-5-sulfamoylbenzoic acid is related to fluconazole in that it contains a benzoate moiety and an amide group. These structural features confer antibacterial and antif

    Formula:C8H9NO5S
    Purezza:Min. 95%
    Peso molecolare:231.23 g/mol

    Ref: 3D-IM145487

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  • 2-((2-Methyl-1-(propionyloxy)propoxy)(4-phenylbutyl)phosphoryl)acetic acid

    CAS:
    2-((2-Methyl-1-(propionyloxy)propoxy)(4-phenylbutyl)phosphoryl)acetic acid (KZPBA) is a zoonotic antibiotic that has been shown to be active against agalactiae. It is a prodrug, which is metabolized to the active form, KZPBA, in humans and other mammals. The mechanism of action of KZPBA is not yet known; however, it has been hypothesized that its activity may be due to inhibition of DNA gyrase and topoisomerase IV. This drug has also been shown to have an effect on mastitis in dairy cows.
    Formula:C19H29O6P
    Purezza:Min. 95%
    Peso molecolare:384.4 g/mol

    Ref: 3D-IM27637

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  • Aminopentamide sulfate

    CAS:

    Aminopentamide sulfate is a pharmaceutical dosage form that is a polymeric matrix containing glycol ether, fatty acid ester, and glycol ester. It is used as a local anesthetic to numb the skin and other tissues. Aminopentamide sulfate can be administered topically or by injection into the body. It has been shown to have therapeutic effects on animals with pain-related conditions such as arthritis and neuropathy. The intramolecular hydrogen bonds in aminopentamide sulfate are thought to be formed between the carbonyl group of atropine sulfate and the hydroxyl groups of benzimidazole derivatives. These functional groups form hydrogen bonds with fatty alcohols in the matrix, which may help stabilize it.

    Formula:C19H26N2O5S
    Purezza:Min. 95%
    Peso molecolare:394.5 g/mol

    Ref: 3D-VAA70177

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  • 2-(4-Formylphenyl)propionic acid - Racemic

    CAS:

    2-(4-Formylphenyl)propionic acid is a racemic mixture of 2-formylphenylacetic acid and 4-formylphenylacetic acid. This compound is used in the treatment of bacterial infections and inflammation. It is an organic solution that can be injected, administered orally, or applied topically. The 2-(4-formylphenyl)propionic acid has been shown to have anti-inflammatory properties, but also has side effects such as skin irritation when it is applied topically. This drug can also cause nausea, vomiting, and diarrhea when administered orally.

    Formula:C10H10O3
    Purezza:Min. 95%
    Colore e forma:White Powder
    Peso molecolare:178.18 g/mol

    Ref: 3D-IF27430

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  • (trans)-4-Propyl-1-methyl-L-proline

    CAS:

    (trans)-4-Propyl-1-methyl-L-proline is a synthetic compound that has been used in the past as an impurity standard in the synthesis of several drugs, including metaxalone and aminopyrine. It is also found to have pharmacological effects on its own and was used as a drug product for the treatment of rheumatoid arthritis. (trans)-4-Propyl-1-methyl-L-proline is not listed in any pharmacopoeia or international list of approved drugs.

    Formula:C9H17NO2
    Purezza:Min. 95%
    Colore e forma:White/Off-White Solid
    Peso molecolare:171.24 g/mol

    Ref: 3D-FP27224

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  • Remdesivir related compound 9

    CAS:

    Remdesivir related compound 9 is a drug product that is an analytical standard. It is a natural API impurity, which has been synthesized for use as an impurity standard. This compound has been custom synthesized to be used as a research and development chemical. CAS No. 1439900-56-7 is the number of this synthetic drug product. It can be used in HPLC standards and it meets pharmacopoeia requirements for purity. The niche market for this compound is high purity analytical standards, including HPLC standards.

    Formula:C21H27N2O7P
    Purezza:Min. 95%
    Peso molecolare:450.42 g/mol

    Ref: 3D-IR177097

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  • Bendamustine isopropyl ester

    CAS:

    Bendamustine isopropyl ester is a synthetic, high purity drug product. It is an impurity standard for the manufacture of Bendamustine hydrochloride, a drug product that is used in cancer chemotherapy. Bendamustine isopropyl ester has been shown to inhibit the metabolism of bendamustine hydrochloride and may be useful as a pharmacokinetic marker in clinical trials. Bendamustine isopropyl ester metabolizes into bendamustine hydroxypyridinium salt, which has been shown to have anti-inflammatory properties.

    Formula:C19H27Cl2N3O2
    Purezza:Min. 95%
    Peso molecolare:400.30 g/mol

    Ref: 3D-NCC02025

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  • Chloromethyl olanzapinium chloride

    CAS:

    Chloromethyl olanzapinium chloride is an analytical reference material that can be used as a standard for HPLC-UV analysis. It is also used in the development of new drugs and as an impurity standard during drug manufacturing. Chloromethyl olanzapinium chloride has been shown to be a metabolite of Olanzapine, which is a niche drug product that is not commercially available. Chloromethyl olanzapinium chloride is listed by the USP, EP and JP as a drug product impurity. It can be synthesized from natural or synthetic sources.

    Formula:C18H22Cl2N4S
    Purezza:Min. 95%
    Colore e forma:Powder
    Peso molecolare:397.37 g/mol

    Ref: 3D-IC171347

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