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APIs per la ricerca e le impurità

APIs per la ricerca e le impurità

I principi attivi farmaceutici (API) sono le sostanze nei farmaci responsabili dei loro effetti terapeutici. In questa sezione troverai una vasta gamma di API destinati all'uso in ricerca. Questi composti sono essenziali per lo sviluppo, il test e la validazione di nuove formulazioni farmaceutiche. Presso CymitQuimica, offriamo API di alta qualità per supportare la ricerca nella scoperta e nello sviluppo di farmaci.

Sottocategorie di "APIs per la ricerca e le impurità"

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  • N-Benzyl N-demethyl trimebutine

    CAS:

    N-Benzyl N-demethyl trimebutine is an analytical standard that is used in the development of new drugs. It is a synthetic compound and has not been found in any natural sources. The CAS number for this compound is 1329834-94-7, and it can be purchased as an impurity standard or as a custom synthesis. N-Benzyl N-demethyl trimebutine has two impurities: benzyl alcohol and demethyltrihexyphenidyl. This compound can be used as a pharmacopoeia or HPLC standard.

    Formula:C28H33NO5
    Purezza:Min. 95%
    Peso molecolare:463.6 g/mol

    Ref: 3D-EDC83494

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  • Retinyl retinoate

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    CAS:

    Retinyl retinoate is a synthetic retinoid that is chemically stable and has been shown to be effective in clinical studies. Retinyl retinoate is a lipophilic molecule with antioxidant properties, and it also has the ability to bind to hyaluronic acid and other natural compounds to maintain skin condition. This compound is synthesized by esterification of all-trans-retinoic acid with fatty acids, such as oleic acid or linoleic acid. The chemical structure of this compound can be determined by nuclear magnetic resonance spectroscopy.

    Formula:C40H56O2
    Purezza:Min. 95%
    Peso molecolare:568.9 g/mol

    Ref: 3D-QAA49886

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  • Varenicline N-oxide

    CAS:

    Varenicline N-oxide is a synthetic drug product. It is the metabolite of varenicline, which is used as an aid to smoking cessation. Varenicline N-oxide has shown anti-inflammatory properties in vitro and in vivo, and may be useful for treating inflammatory diseases. Varenicline N-oxide also has been shown to inhibit the production of nitric oxide in macrophages and prevent the release of tumor necrosis factor alpha by macrophages.

    Formula:C13H13N3O
    Purezza:Min. 95%
    Peso molecolare:227.26 g/mol

    Ref: 3D-IV177544

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  • N-4,5[Acetylamino)methyl]desmopressin


    N-4,5[Acetylamino)methyl]desmopressin is a synthetic drug product that is used as an analytical standard for the identification and quantitation of desmopressin in pharmaceutical preparations. It is also used as an impurity standard for HPLC analysis. This product has been synthesized using a custom synthesis process, and has been shown to be suitable for use in drug development and research and development. N-4,5[Acetylamino)methyl]desmopressin is also available as a high purity HPLC standard that meets pharmacopoeia requirements.

    Purezza:Min. 95%

    Ref: 3D-IA173214

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  • Albendazole sulfone

    CAS:

    Albendazole sulfone is a metabolite of the drug albendazole. It is used as an analytical standard to measure the concentration of albendazole in human plasma and urine samples. The concentration-time curve for albendazole sulfone can be determined using a nonlinear regression analysis, with the rate constant being calculated from the slope and intercept. This method has been shown to be accurate for predicting pharmacokinetic parameters in humans. Albendazole sulfone is also used as a probe in wastewater treatment studies, where it binds to colloidal gold particles that are used to visualize the removal of small particles by microorganisms.

    Formula:C12H15N3O4S
    Purezza:Min. 95 Area-%
    Colore e forma:Powder
    Peso molecolare:297.33 g/mol

    Ref: 3D-IA17258

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  • Ethyl 2-(6-amino-2,3-dichlorobenzyl)glycine

    CAS:

    Ethyl 2-(6-amino-2,3-dichlorobenzyl)glycine is a drug product with a CAS number of 70406-92-7. It has an analytical purity of greater than 98% and is supplied as a white powder. This product is metabolized in the human body to form an active metabolite. The chemical name for this drug product is ethyl 2-(6-amino-2,3-dichlorobenzyl)glycine, which can be found in the pharmacopoeia under the name of 6′ amino 2,3′ dichlorobenzyl glycine.

    Formula:C11H14Cl2N2O2
    Purezza:Min. 95%
    Peso molecolare:277.15 g/mol

    Ref: 3D-IE22945

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  • Bortezomib impurity 76

    CAS:

    Bortezomib impurity 76 is an analytical reference material that is used in the development and production of pharmaceuticals. It is a high purity, HPLC standard for use as an impurity in the manufacture of bortezomib API. This material is a metabolite of bortezomib and it has been shown to be pharmacologically active. Bortezomib impurity 76 can also be used as an HPLC standard for drug product analysis.

    Formula:C21H44BNO2Si2
    Purezza:Min. 95%
    Colore e forma:Powder
    Peso molecolare:409.56 g/mol

    Ref: 3D-IB181070

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  • rac Enterodiol-d6

    CAS:

    Racemic Enterodiol-d6 is a high purity synthetic racemic compound that is used as an impurity standard for use in HPLC. The CAS number for Racemic Enterodiol-d6 is 104411-12-3. Racemic Enterodiol-d6 has a melting point of 232°C and a boiling point of 464°C at atmospheric pressure. This product can be customized to meet the needs of your research, development, or drug production needs.

    Formula:C18H22O4
    Purezza:Min. 95%
    Peso molecolare:308.4 g/mol

    Ref: 3D-EEA41112

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  • Ros 234 dioxalate

    CAS:

    Ros 234 is a dioxalate salt of rosiglitazone, and is an anti-cancer agent that inhibits the growth of cancer cells. Ros 234 has been shown to inhibit inflammatory conditions such as asthma, rheumatoid arthritis, and colitis. It also modulates immune and autoimmune responses.

    Formula:C17H19N5O8
    Purezza:Min. 95%
    Peso molecolare:421.4 g/mol

    Ref: 3D-GWC94193

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  • Roxithromycin impurity E

    CAS:

    Roxithromycin impurity E is a metabolite of roxithromycin. It is a yellow powder with a melting point of about 130°C and a molecular weight of 226.14g/mol. Roxithromycin impurity E has been shown to be an inhibitor of CYP3A4 and CYP2D6, as well as an inducer of CYP1A2. This impurity can be used for the research and development of roxithromycin, as well as production of analytical standards for HPLC analysis.

    Formula:C40H74N2O15
    Purezza:Min. 95%
    Peso molecolare:823.02 g/mol

    Ref: 3D-IR106453

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  • 9-Epimitomycin B

    CAS:

    9-Epimitomycin B is a water-soluble, alkoxy-substituted amino compound that is used medicinally. It has antibacterial activity and has been shown to be effective against Gram-positive bacteria such as Staphylococcus aureus, Streptococcus pyogenes, and Enterococcus faecalis. 9-Epimitomycin B inhibits the growth of these bacteria by binding to their ribosomes and inhibiting protein synthesis. The carbon atoms in 9-epimitomycin B are linked to an alkoxy group at one end, which causes it to have a higher affinity for bacterial ribosomes than human ribosomes. 9-Epimitomycin B also binds to mitomycin C, which may be responsible for its antimetabolite properties.

    Formula:C16H19N3O6
    Purezza:Min. 95%
    Peso molecolare:349.34 g/mol

    Ref: 3D-NAA16490

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  • 4,6-Dimethoxy-β-methyl-3-phenoxy ambrisentan

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    CAS:
    4,6-Dimethoxy-β-methyl-3-phenoxy ambrisentan is a synthetic drug with a high purity and pharmacopoeia. It belongs to the group of drugs called prostanoids, which are lipid molecules that act as hormones. 4,6-Dimethoxy-β-methyl-3-phenoxy ambrisentan is used in research and development for the treatment of pulmonary arterial hypertension. It is an impurity standard for HPLC analysis. This compound can be custom synthesized for drug product research and development. Metabolism studies have been conducted on this compound. The metabolites have been identified as 4,6-dimethoxy-(E)-2-[(E)-2-(4'-methylbenzylidene)ethenyl]-3-[(Z)-1-(4'-methylbenzylidene)ethenyl]ambrinol (M1), 4,6-dimethoxy-(E)-
    Formula:C22H22N2O6
    Purezza:Min. 95%
    Peso molecolare:410.4 g/mol

    Ref: 3D-JGA30803

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  • Carfilzomib (2R,4S)-diol

    CAS:

    Carfilzomib is a drug product that belongs to the class of drugs called proteasome inhibitors. It has been used in the treatment of multiple myeloma, and is also being studied for use in other diseases such as chronic obstructive pulmonary disease and cystic fibrosis. Carfilzomib is an impurity standard for HPLC analysis and an analytical reference material. It is also used as a pharmacopoeia reference material. Carfilzomib is a natural product, with the synthetic route being developed by researchers at Pfizer. The drug product contains 2R,4S-diol as its main metabolite and impurity.

    Formula:C40H59N5O8
    Purezza:Min. 95%
    Peso molecolare:737.90 g/mol

    Ref: 3D-RLC17275

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  • Haloxyfop-d4

    CAS:

    Haloxyfop-d4 is an analog of the herbicide Haloxyfop that has been shown to have anticancer properties. It works by inhibiting kinases, which are enzymes that play a key role in cell division and growth. This inhibition leads to apoptosis, or programmed cell death, in cancer cells. Haloxyfop-d4 has been found to be effective against a variety of human cancer cell lines, including those resistant to other anticancer drugs. In addition, it has been shown to inhibit the growth of tumors in animal models. This drug is metabolized in the liver and excreted in urine. It is not known to interact with other drugs such as rifampicin or protein kinase inhibitors.

    Formula:C15H11ClF3NO4
    Purezza:Min. 95%
    Peso molecolare:365.72 g/mol

    Ref: 3D-CFA89334

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  • RS 67506 hydrochloride

    CAS:

    RS 67506 hydrochloride is a biochemical that is used in experimental and descriptor studies. The ketone group has been found to be an important part of the molecular structure. RS 67506 hydrochloride has been shown to have a number of biological properties, including inhibition of the synthesis of neurotransmitters such as dopamine, serotonin and norepinephrine; it also has anti-nervous system activity. This chemical was also found to inhibit the synthesis of prostaglandin E2 in human neutrophils. It is hypothesized that RS 67506 hydrochloride may inhibit phospholipase A2, which would prevent the release of arachidonic acid from phospholipids into the cell membrane and block the production of eicosanoids.

    Formula:C18H29Cl2N3O4S
    Purezza:Min. 95%
    Peso molecolare:454.4 g/mol

    Ref: 3D-TGA98661

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  • cis-Tadalafil

    CAS:

    Cis-Tadalafil is a potent inhibitor of phosphodiesterase 5, which is used to treat erectile dysfunction (ED) and primary pulmonary hypertension (PPH). It works by increasing blood flow to the penis, allowing men with ED to achieve and maintain an erection. Cis-Tadalafil is also used to treat symptoms of prostatic hyperplasia (enlarged prostate) in men. This drug has been shown to be effective in treating PPH by reducing pulmonary arterial pressure and improving exercise capacity. Cis-Tadalafil belongs to the carboline class of drugs and is a phosphodiesterase 5 inhibitor that selectively inhibits cGMP-specific phosphodiesterase type 5 (PDE5). This drug has been shown to be highly effective in treating both ED and PPH with minimal side effects.

    Formula:C22H19N3O4
    Purezza:Min. 95%
    Colore e forma:White/Off-White Solid
    Peso molecolare:389.4 g/mol

    Ref: 3D-FT27987

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  • Acarbose Impurity E

    CAS:

    Acarbose Impurity E is an impurity found in acarbose. It is a natural, API impurity and is a synthetic impurity standard. Acarbose Impurity E has been used in drug development research and development, as well as in the HPLC analysis of acarbose to generate a pharmacopoeia-grade purity standard.

    Purezza:Min. 95%

    Ref: 3D-FA175652

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  • 3-Dimethylaminopropyl-2-benzylaminobenzoate hydrochloride

    CAS:

    3-Dimethylaminopropyl-2-benzylaminobenzoate hydrochloride is a versatile compound with various characteristics and applications. It has been found to have diverse effects on different biological processes. This compound has shown potential as an antimuscarinic agent, which means it can block the action of acetylcholine at muscarinic receptors in the body.

    Formula:C19H25ClN2O2
    Purezza:Min. 95%
    Peso molecolare:348.9 g/mol

    Ref: 3D-WMD18565

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  • Ivermectin impurity I

    CAS:

    Ivermectin impurity I is an analytical standard that is used for pharmacopoeia and custom synthesis. It is a natural metabolite of the drug Ivermectin, which has been shown to have anti-inflammatory properties in mice. Ivermectin impurity I binds to nicotinic acetylcholine receptors, leading to muscle paralysis and death. This compound is found in high purity for research and development purposes.

    Formula:C48H74O14
    Purezza:Min. 95%
    Colore e forma:Powder
    Peso molecolare:875.09 g/mol

    Ref: 3D-II167729

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  • Piperacilloic acid

    CAS:

    Piperacilloic acid is a synthetic compound that exhibits antibacterial activity. It has been shown to be effective against human pathogens, including urothelial carcinoma and human serum. Piperacilloic acid binds to the amino acids lysine and arginine in bacterial proteins and inhibits protein synthesis by inhibiting the function of enzymes that require these amino acids for their activity. The potency of piperacillin is low, but it is activated by hydrolysis in the acidic environment of the stomach or intestinal tract. Piperacilloic acid also has potential as a contraceptive agent because it may inhibit transcriptional regulation of genes that are involved in sperm production.

    Formula:C23H29N5O8S
    Purezza:(Elemental Analysis) Min. 90 Area-%
    Colore e forma:Powder
    Peso molecolare:535.57 g/mol

    Ref: 3D-FP27061

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