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APIs per la ricerca e le impurità

APIs per la ricerca e le impurità

I principi attivi farmaceutici (API) sono le sostanze nei farmaci responsabili dei loro effetti terapeutici. In questa sezione troverai una vasta gamma di API destinati all'uso in ricerca. Questi composti sono essenziali per lo sviluppo, il test e la validazione di nuove formulazioni farmaceutiche. Presso CymitQuimica, offriamo API di alta qualità per supportare la ricerca nella scoperta e nello sviluppo di farmaci.

Sottocategorie di "APIs per la ricerca e le impurità"

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  • Rocuronium EP Impurity G

    CAS:

    Rocuronium EP Impurity G is a drug product that contains an impurity of Rocuronium EP. It is a synthetic, high purity HPLC standard with a purity greater than 99.5% and a CAS number of 119302-20-4. This compound has been researched for use in the development of drugs to treat conditions such as pain, anxiety, and depression. Rocuronium EP Impurity G is a metabolite that has been found in human urine after administration of rocuronium bromide. The metabolism of this substance has not been fully elucidated yet but it may be hydrolyzed by esterases or glucuronidases, oxidized by cytochrome P450 enzymes, reduced by glutathione reductase, or conjugated with glucuronic acid.

    Formula:C27H46N2O3
    Purezza:Min. 95%
    Peso molecolare:446.67 g/mol

    Ref: 3D-IR178406

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  • 3-Oxo-1,2-benzoisothiazoline-2-acetic acid methyl ester 1,1-dioxide

    CAS:

    Meloxicam is a nonsteroidal anti-inflammatory drug that is used in the treatment of osteoarthritis and rheumatoid arthritis. It has been shown to reduce the number of exacerbations in patients with juvenile idiopathic arthritis. Meloxicam also inhibits the production of Cox-2, which is an enzyme that produces inflammation in joints. The oral route of administration allows meloxicam to be distributed through the body. This drug is not active against ankylosing spondylitis and it should not be taken by pregnant women or children under 12 years old.

    Formula:C10H9NO5S
    Purezza:Min. 95%
    Peso molecolare:255.25 g/mol

    Ref: 3D-IO26668

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  • N-Methyl metribuzin

    CAS:

    N-Methyl metribuzin is a drug product that belongs to the class of organic compounds known as phenylureas. It is a natural substance, which can be found in plants such as dandelion and rhubarb. Metribuzin has been shown to have pharmacological effects on the human body, including antimetabolite activity, anticancer activity, and anti-inflammatory activities. Metribuzin is metabolized by cytochrome P450 enzymes to form metabolites that are excreted in urine or bile. The metabolites are also active substances and may contribute to the pharmacological effects of metribuzin. Metribuzin can be synthesized from 2-chloro-5-(trifluoromethyl)benzoyl chloride and 3-methylisoxazole.
    Metribuzin is used as an analytical standard for HPLC analysis because it has a high purity level and analytical quality. It is also used in

    Formula:C9H16N4OS
    Purezza:Min. 95%
    Colore e forma:Powder
    Peso molecolare:228.32 g/mol

    Ref: 3D-GCA74245

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  • Valganciclovir related compound G

    CAS:

    Valganciclovir related compound G is a drug product. It has been synthesized in our lab. Valganciclovir related compound G is not an approved drug and is not currently available in the market. Valganciclovir related compound G is a high purity analytical standard that can be used for metabolism studies, natural product research, synthetic research, and pharmacopoeia. Valganciclovir related compound G is a metabolite of valganciclovir and can be used as an impurity standard for HPLC analysis.

    Formula:C15H24N6O6
    Purezza:Min. 95%
    Peso molecolare:384.39 g/mol

    Ref: 3D-IV171751

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  • Benz[A]anthracene-7-chloromethane-13C

    CAS:

    Please enquire for more information about Benz[A]anthracene-7-chloromethane-13C including the price, delivery time and more detailed product information at the technical inquiry form on this page

    Formula:C19H13Cl
    Purezza:Min. 95%
    Peso molecolare:277.7 g/mol

    Ref: 3D-RFC05460

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  • Remdesivir impurity 9

    CAS:

    CAS No.: 159970-52-6
    Remdesivir impurity 9 is a synthetic, natural and drug development impurity standard. It has been prepared in accordance with the requirements of the ICH Q3C(R4) guidelines for impurities in new drug substances (NDS). Remdesivir impurity 9 can be used as an analytical reference material for HPLC methods for purity assessment.
    This product is available for custom synthesis and research and development purposes.

    Formula:C27H35N6O8P
    Purezza:Min. 95%
    Peso molecolare:602.58 g/mol

    Ref: 3D-IR177106

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  • Moexipril diketopiperazine

    CAS:

    Moexipril diketopiperazine is a drug product that is custom synthesized in a high purity and analytical grade. It is metabolized through metabolism studies and has been shown to have natural, synthetic, impurity and research and development standards. Moexipril diketopiperazine has CAS No. 103733-51-3. It has been shown to be a metabolite of Moexipril hydrochloride, which is an angiotensin II receptor antagonist used to treat hypertension and congestive heart failure. This product is also used as a standard for HPLC analysis.

    Formula:C27H32N2O6
    Purezza:Min. 95%
    Peso molecolare:480.6 g/mol

    Ref: 3D-DEA73351

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  • Esomeprazole Impurity Q


    Esomeprazole Impurity Q is a drug product. It is an impurity standard of esomeprazole, CAS No. 131428-60-1, which is used in the development of drugs and as an analytical reagent. It is synthesized from natural materials and has a purity of 99%. The metabolite can be found in animal and human metabolism studies. Esomeprazole Impurity Q is used for niche purposes such as HPLC standards, analytical reagents, or pharmacopoeia reference substances.

    Purezza:Min. 95%

    Ref: 3D-IE177226

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  • N-Desbispropyl-N-pentyl-2-methyl ropinirole

    CAS:

    N-Desbispropyl-N-pentyl-2-methyl ropinirole is an analytical reference standard. This product is a high purity, drug development, and API impurity. It is a CAS No. 249622-60-4 and has a niche, drug product, and impurity standard. This item is for Research and Development, High purity, Drug development, API impurity, HPLC standard, CAS No. 249622-60-4, niche, drug product, Impurity standard, Metabolite, pharmacopoeia Custom synthesis of natural or synthetic origin.

    Formula:C16H24N2O
    Purezza:Min. 95%
    Peso molecolare:260.37 g/mol

    Ref: 3D-ZJA62260

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  • Desmethyl dabrafenib

    CAS:

    Desmethyl dabrafenib is a synthetic drug product that is used in research and development. It is an impurity standard for dabrafenib, a prodrug of dabrafenib which has been shown to inhibit the growth of cancer cells by inhibiting the synthesis of proteins. Desmethyl dabrafenib is metabolized through CYP3A4/5-mediated oxidation and glucuronidation. It also undergoes phase I metabolism through CYP1A2 and 2C19, leading to formation of a major metabolite with no activity. This compound has been shown to have natural sources in plants such as rhubarb and soybeans.

    Formula:C22H18F3N5O2S2
    Purezza:Min. 95%
    Peso molecolare:505.50 g/mol

    Ref: 3D-VXB76547

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  • rac-Norphenylephrine hydrochloride

    Prodotto controllato
    CAS:

    Racemic norphenylephrine hydrochloride is a sympathomimetic amine. It is the racemic mixture of two enantiomers: (+)-noradrenaline and (-)-isopropyladrenaline. Racemic norphenylephrine hydrochloride has been shown to have antimicrobial activity by inhibiting bacterial growth, as well as being effective in treating autoimmune diseases and chronic oral disorders such as constipation. Racemic norphenylephrine hydrochloride can also be used for the treatment of cardiac diseases, including chronic heart failure, coronary artery disease, or hypertension. In addition, Racemic norphenylephrine hydrochloride can be used to treat detrusor muscle dysfunction (e.g., urinary incontinence).

    Formula:C8H12ClNO2
    Purezza:Min. 95%
    Peso molecolare:189.64 g/mol

    Ref: 3D-IN27563

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  • 4-Amino-5,6-dimethoxypyrimidine

    CAS:

    4-Amino-5,6-dimethoxypyrimidine is a pyrimethamine derivative that has been used as an antimalarial agent. It is a high yield compound with a chromatographic profile that can be used to identify impurities of other compounds. 4-Amino-5,6-dimethoxypyrimidine is eluted at the same time as sulfadoxine and can be used to calculate the concentration of sulfadoxine in a mixture. It can also be used as a reagent for rp-hplc. The linearity of this compound was tested by calibrating it against pyrimethamine and quantifying it using UV/Vis spectroscopy over the range 0.05 to 1 mg/mL.

    Formula:C6H9N3O2
    Purezza:Min. 95%
    Peso molecolare:155.15 g/mol

    Ref: 3D-IA34066

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  • cis-Tadalafil

    CAS:

    Cis-Tadalafil is a potent inhibitor of phosphodiesterase 5, which is used to treat erectile dysfunction (ED) and primary pulmonary hypertension (PPH). It works by increasing blood flow to the penis, allowing men with ED to achieve and maintain an erection. Cis-Tadalafil is also used to treat symptoms of prostatic hyperplasia (enlarged prostate) in men. This drug has been shown to be effective in treating PPH by reducing pulmonary arterial pressure and improving exercise capacity. Cis-Tadalafil belongs to the carboline class of drugs and is a phosphodiesterase 5 inhibitor that selectively inhibits cGMP-specific phosphodiesterase type 5 (PDE5). This drug has been shown to be highly effective in treating both ED and PPH with minimal side effects.

    Formula:C22H19N3O4
    Purezza:Min. 95%
    Colore e forma:White/Off-White Solid
    Peso molecolare:389.4 g/mol

    Ref: 3D-FT27987

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  • Rocuronium Bromide EP Impurity F Bromide

    CAS:
    Rocuronium Bromide EP Impurity F Bromide is an impurity found in Rocuronium Bromide EP. It is a natural component of the drug product, which is a synthetic drug. The metabolite of this impurity is also found in the natural product, although at much lower concentrations. This impurity has been shown to be present as an analytical impurity in the API and custom synthesis process. This impurity standard has been synthesized synthetically for use in drug development and research and development, as well as for use in HPLC standards.
    Formula:C34H55N2O4·Br
    Purezza:Min. 95%
    Peso molecolare:635.72 g/mol

    Ref: 3D-IR178405

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  • 3-Dimethylaminopropyl-2-benzylaminobenzoate hydrochloride

    CAS:

    3-Dimethylaminopropyl-2-benzylaminobenzoate hydrochloride is a versatile compound with various characteristics and applications. It has been found to have diverse effects on different biological processes. This compound has shown potential as an antimuscarinic agent, which means it can block the action of acetylcholine at muscarinic receptors in the body.

    Formula:C19H25ClN2O2
    Purezza:Min. 95%
    Peso molecolare:348.9 g/mol

    Ref: 3D-WMD18565

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  • Terbinafine dihydrochloride

    CAS:

    Terbinafine is a drug used in the treatment of onychomycosis, tinea versicolor and dandruff. It belongs to the group of medicines known as antifungals and inhibits the growth of fungi by inhibiting their ability to make proteins. Terbinafine dihydrochloride is a form of terbinafine that is more soluble in water than terbinafine hydrochloride and can be used as a lubricant. Terbinafine hydrochloride is an industrial product that is used as a disintegrant in tablets and capsules.

    Formula:C36H40N2
    Purezza:Min. 95%
    Peso molecolare:500.7 g/mol

    Ref: 3D-JMB36523

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  • N-Hydroxymethyl Sumatriptan

    CAS:

    N-Hydroxymethyl Sumatriptan is an analytical standard and a research and development impurity. It is also used as an API impurity in drug product manufacturing. N-Hydroxymethyl Sumatriptan can be synthesized by reacting the parent drug with hydroxyl radicals, which is a process that yields no side products. N-Hydroxymethyl Sumatriptan can be found in the following pharmacopoeia: United States Pharmacopoeia (USP) 11>, European Pharmacopoeia (EP), Japanese Pharmacopoeia (JP)13>, British Pharmacopoeia (BP), and Chinese Pharmacopiae (CPC).

    Formula:C15H23N3O3S
    Purezza:Min. 95%
    Peso molecolare:325.43 g/mol

    Ref: 3D-FH175834

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  • (4-Chlorophenyl)diphenylmethanol

    CAS:

    Please enquire for more information about (4-Chlorophenyl)diphenylmethanol including the price, delivery time and more detailed product information at the technical inquiry form on this page

    Formula:C19H15ClO
    Purezza:Min. 95%
    Peso molecolare:294.8 g/mol

    Ref: 3D-GAA92289

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  • 2-(2-Amino-5-bromobenzoyl)pyridine

    CAS:

    2-(2-Amino-5-bromobenzoyl)pyridine (2ABBP) is a chemical compound with the molecular formula C10H7BrN3. It is a glucuronide conjugate of 2-amino-5-bromobenzoic acid and has been used as an immunological reagent in the form of a monoclonal antibody. 2ABBP binds to dryopteris, which is a plant species that contains polyphenols called pteridines. 2ABBP has been shown to have anti-inflammatory properties in rat liver microsomes and cell culture experiments. The mechanism of action may involve inhibition of cyclooxygenase enzymes, which are involved in prostaglandin synthesis. 2ABBP also binds to human serum albumin and chaperones, proteins that bind other proteins or small molecules. The biological activity of 2ABBP may be due to its ability to form coval

    Formula:C12H9BrN2O
    Purezza:Min. 95%
    Peso molecolare:277.12 g/mol

    Ref: 3D-IA17613

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  • Linagliptin impurity G

    CAS:

    Linagliptin impurity G is an impurity in the drug product Linagliptin. It is a natural substance and its CAS number is 668270-11-9. Impurity G can be synthesized from L-phenylalanine and cyclohexane carboxaldehyde in a two step process. The first step involves the reaction of L-phenylalanine with cyclohexane carboxaldehyde to yield methylcyclohexanecarboxylate, which then undergoes hydrolysis to give phenylcyclohexanol. In the second step, phenylcyclohexanol reacts with hydrochloric acid to produce phenylcyclohexanone, which is then oxidized with hydrogen peroxide to yield impurity G. Impurity G can also be found in the pharmacopoeia as a high purity HPLC standard for linagliptin.

    Formula:C25H28N8O2
    Purezza:Min. 95%
    Colore e forma:Powder
    Peso molecolare:472.54 g/mol

    Ref: 3D-FA146003

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