APIs per la ricerca e le impurità

Brobactam is a potent inhibitor of beta-lactamase enzymes and is often used in combination with other antibiotics to enhance their efficacy. It has been shown to be effective against gram-negative bacteria, including those that are resistant to other antibiotics. Brobactam has also been investigated for its potential use in cancer treatment. Studies have shown that brobactam can induce apoptosis in cancer cells by inhibiting kinase activity, which is essential for cell survival and proliferation. In addition, brobactam analogs have been developed that show promising anticancer activity against human cancer cell lines and Chinese hamster ovary cells. Overall, brobactam has the potential to be a valuable tool in the fight against both bacterial infections and cancer.

Epinephrine sulfonic acid-d3 is a synthetic, high purity, pharmacopoeia, drug development, analytical standard. It is used as an impurity standard, and in the synthesis of epinephrine sulfone. Epinephrine sulfonic acid-d3 has been shown to be a metabolite of epinephrine and its metabolites. This product has been synthesized and characterized by HPLC analysis using an ion-pairing agent and a gradient elution with water:acetonitrile (0.1% formic acid) (75:25).

Please enquire for more information about (+)-Papaveroxinoline acetate including the price, delivery time and more detailed product information at the technical inquiry form on this page

Sulfo EGS is a potent analog that has shown promising anticancer activity in various human cancer cell lines. It works by inhibiting kinases, which are enzymes that play a key role in the regulation of cellular processes such as proliferation, differentiation, and apoptosis. Sulfo EGS has been found to be particularly effective against Chinese hamster ovary cells and tumor cells from medicinal plants. This inhibitor also shows potential for use in the development of kinase inhibitors for cancer therapy. In addition, Sulfo EGS is commonly used as a cross-linking reagent to covalently link proteins or protein complexes in urine or other biological samples for further analysis. Overall, Sulfo EGS is an important tool for cancer research and drug development.

Please enquire for more information about 3-(1,1-Difluoro-2-propen-1-yl)-2(1H)-quinoxalinone including the price, delivery time and more detailed product information at the technical inquiry form on this page

2S-OMPT is a protein that is expressed in the cell. It is involved in transcriptional regulation, and can be assayed using k562 cells. 2S-OMPT has been shown to be associated with cancer. It also increases resistance to chemotherapeutic agents by inhibiting cation channels or inducing apoptosis of leukemia cells. 2S-OMPT may also play an important role in intracellular calcium ion concentrations, as it binds to the extracellular domain of sphingosine kinase and inhibits its activity. This inhibition leads to decreased levels of intracellular calcium ions, which may modulate chemokine production by chemoresistant cancer cells.

Apigenin 5-o-β-D-glucuronide is a natural compound derived from the Chinese herb scutellaria baicalensis. It has been shown to be effective in reducing pro-inflammatory cytokines and prostate cancer cells. Apigenin 5-o-β-D-glucuronide is one of the many phenolic acids found in plants, which are known for their antioxidant and anti inflammatory properties. The plant metabolizes apigenin 5-o-β-D-glucuronide by conjugating it with glucuronic acid, forming the glucuronide conjugate. The bioactive phenolic compounds in plants are well studied and have been shown to have anticancer properties.

Triphenylmethanol (TPM) is an inhibitor of the enzyme alcohol dehydrogenase. It is synthesized by reacting p-hydroxybenzoic acid with a hydroxyl group in the presence of trifluoroacetic acid and potassium carbonate. The reaction solution was then analyzed by x-ray crystallography, revealing the molecular structure of TPM. TPM binds to the metal ion in a hydroxyl group, preventing alcohol dehydrogenase from oxidizing ethanol to acetaldehyde. This mechanism also explains why TPM inhibits other enzymes that use this same metal ion cofactor such as carboxypeptidase A and aminopeptidase P, which are involved in protein synthesis and degradation.

The human red blood cell (RBC) is a non-nucleated cell in the human blood that carries oxygen to the body's cells. The erythrocyte is characterized by its biconcave shape and its lack of organelles. It has a volume of about 80 fL, and a diameter of about 7 micrometers. The RBCs are produced in bone marrow from precursor cells that differentiate into erythroid progenitor cells. This drug binds to the hemoglobin molecules in the red blood cells and alters their shape, causing an increase in their deformability. In addition, this drug decreases the viscosity of the plasma outside of the red blood cell, which increases its extravascular sensitivity. Evaluations have been performed on low doses to evaluate sensitivities within capillaries with microscopy parameters such as magnification and resolution. These evaluations have shown that this drug can be used for quantifying changes in capillary size due to low doses (

Please enquire for more information about Loxoprofen methyl-d3 ethyl ester including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 1-[(4-Chlorophenyl)phenylmethyl]-4-(phenylsulfonyl)piperazine including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 4-[(3-Chlorophenyl)sulfonyl]benzenamine including the price, delivery time and more detailed product information at the technical inquiry form on this page

Vitalethine is a protein analog that has been shown to induce apoptosis in cancer cells. It acts as a kinase inhibitor and specifically targets the hepcidin pathway, which is involved in tumor growth and metastasis. Vitalethine has been tested on human cancer cell lines and has shown potent anticancer activity. This protein analog may have potential therapeutic applications for the treatment of various types of cancers. Vitalethine can be detected in urine samples and may serve as a biomarker for cancer diagnosis and monitoring.

Please enquire for more information about PBT Impurity 2 including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about Benz[A]anthracene-7-acetonitrile including the price, delivery time and more detailed product information at the technical inquiry form on this page

Iothalamic acid-d3 is a drug product that is a natural, synthetic, and API impurity. It is used as an analytical standard in metabolism studies and for the quality control of natural Iothalamic acid-d4. Iothalamic acid-d3 also has pharmacopoeia standards for HPLC and high purity.

Nascopine is an analog of nifedipine that acts as a potent inhibitor of protein kinases. It has been shown to induce apoptosis in human cancer cells and inhibit the growth of tumors in Chinese hamsters. Nascopine is an anticancer drug that works by blocking the activity of kinases, which play a crucial role in cancer cell proliferation and survival. This drug has been found to be effective against a wide range of cancers, including breast, prostate, and lung cancer. In addition, Nascopine has been found in urine samples from cancer patients undergoing treatment with this drug. Its unique mechanism of action makes it a promising candidate for further development as an anticancer therapy.

Please enquire for more information about 4-Acetyl-3,4-dihydro-2H-pyrido[3,2-b]oxazine including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 13-Chloro-2-(piperidin-4-ylidene)-4-azatricyclo[9.4.0.0,3,8]pentadeca-1(15),3,5,7,9,11,13-heptaene including the price, delivery time and more detailed product information at the technical inquiry form on this page

Gimatecan is a cycle-specific inhibitor that targets kinases and proteins involved in cancer cell growth. It is a medicinal compound that has been shown to be effective against various types of human cancers. Gimatecan works by inhibiting the activity of protein kinases, which are enzymes that promote cell division and proliferation. This inhibition leads to apoptosis, or programmed cell death, in tumor cells. Gimatecan has been tested extensively in Chinese hamster ovary cells and has demonstrated potent anticancer activity. The compound is excreted primarily through urine and has shown promising results as an anticancer agent in preclinical studies.

Reptoside is a potent anticancer compound that has been shown to induce apoptosis in cancer cells. It is an analog of a protein found in Chinese urine that inhibits the activity of kinases, including cyclin-dependent kinases (CDKs), which play a critical role in cell cycle regulation and tumor growth. Reptoside has been demonstrated to be effective against various human cancers, including breast, lung, and prostate cancer. It works by blocking the activity of specific enzymes involved in tumor growth and proliferation. As a result, Reptoside is considered a promising candidate for the development of new cancer therapies. Its unique mechanism of action makes it highly effective as an inhibitor of cancer cell growth and survival.

4-Carboxy-3-ethoxy)phenyl acetic acid (CPAE) is a fluorescent compound that has been shown to have antidiabetic and luminescence properties. It absorbs light at wavelengths of 340, 405, and 455 nm and emits light at 525 nm. It also absorbs UV light at 310 nm and emits fluorescence at 495 nm. CPAE is formed by the condensation of two molecules of 4-carboxybenzaldehyde with one molecule of ethyl 3-ethoxypropanoate in the presence of a base. The crystals are monoclinic, with space group P2/c and lattice constants a = 12.872(1) Å, b = 7.319(1) Å, c = 17.814(2) Å, β = 98.664(9)°, Z = 2. The molecular weight is 182.24 g/mol and its molecular

Taiwanin C is an analog of dabigatran, a potent inhibitor of kinases that has been shown to have anticancer properties. It has been found to inhibit the growth of tumor cells in vitro and in vivo, inducing apoptosis and reducing protein expression. Taiwanin C has also shown promising results in inhibiting the activity of various kinases involved in cancer cell proliferation and survival. This compound is derived from Chinese herbal medicine and can be detected in urine after administration. Its potential as an anticancer agent makes it a promising area for further research into new cancer therapies.