APIs para pesquisa e impurezas

AZD8848 is a potent inhibitor of the protein kinase that has been shown to have anticancer properties. This analog of capsaicin has been tested in Chinese hamster ovary (CHO) and human cancer cell lines, where it was found to induce apoptosis and inhibit tumor growth. AZD8848 targets specific kinases involved in cancer cell proliferation and survival, making it a promising candidate for cancer treatment. In addition to its anticancer effects, AZD8848 has also been shown to have potential as a urine protein inhibitor, which could be useful in the diagnosis and monitoring of certain types of cancer. Overall, AZD8848 represents an exciting new avenue for the development of novel anticancer therapies.

Acyclovir Impurity O is an impurity found in the drug Acyclovir. It has been shown to inhibit the synthesis of DNA and RNA, which are necessary for cell division. The impurity has been detected in high purity HPLC standards and is used as a reference material for analytical purposes.
Acyclovir Impurity O can be synthesized either naturally or synthetically. It is an impurity that is regulated by the USP, BP, and EP pharmacopeias.

Please enquire for more information about M1-Enrofloxacin hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

Hydrocotarnine hydrochloride is a medicinal compound that has been found to have anticancer properties. It is an inhibitor of protein kinases, which are enzymes that play a key role in regulating cell cycle progression and apoptosis. Hydrocotarnine hydrochloride has been shown to induce apoptosis in cancer cells, making it a promising candidate for the development of novel cancer therapies. This compound has also been identified as a potential inhibitor of tumor growth in Chinese medicine. In vitro studies have demonstrated that hydrocotarnine hydrochloride inhibits the proliferation of various cancer cell lines, suggesting its potential as a therapeutic agent for the treatment of cancer.

Please enquire for more information about 5-Hydroxydeferasirox including the price, delivery time and more detailed product information at the technical inquiry form on this page

Acetylsalicylic acid sodium salt is a potent inhibitor of kinases in both human and Chinese cells. It is an analog of salicylic acid and has been shown to inhibit the growth of cancer cells in vitro. Acetylsalicylic acid sodium salt also induces apoptosis, or programmed cell death, in cancer cells. Additionally, it has been shown to inhibit heparin-induced platelet aggregation and reduce the risk of blood clots. This drug has potential anticancer properties due to its ability to inhibit chitin synthesis, which is necessary for tumor growth and survival. Acetylsalicylic acid sodium salt may be useful as a therapeutic agent for the treatment of cancer and other diseases associated with abnormal kinase activity.

(2S, 4’R, 8’S)-α-Tocopherol is a vitamin E compound that has been shown to have various health benefits. It acts as an antioxidant and protects cells from oxidative damage. Additionally, it has been found to inhibit the growth of cancer cells by inducing apoptosis, inhibiting protein kinase C activity, and blocking the cell cycle. Studies have shown that (2S, 4’R, 8’S)-α-Tocopherol is a potent inhibitor of tumor growth in Chinese hamster ovary cells and human breast cancer cell lines. This vitamin has also been detected in urine samples of individuals who consume a diet rich in vitamin E. Overall, (2S, 4’R, 8’S)-α-Tocopherol is an important anticancer agent with promising therapeutic potential for cancer treatment.

Please enquire for more information about (3-Fluoro-4-morpholin-4-ylphenyl)carbamic acid methyl ester including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about Depyrazine 6,8-dinitrophenyl varenicline including the price, delivery time and more detailed product information at the technical inquiry form on this page

Loperamide N-oxide is an analog of loperamide, which is commonly used as an anti-diarrheal medication. It has been shown to have potential anti-cancer properties by inducing apoptosis in cancer cells. Loperamide N-oxide has also been detected in urine samples from Chinese individuals, indicating its potential use as a biomarker for cancer diagnosis. This compound has been found to inhibit trypsin-like kinases, which are enzymes involved in cell division and proliferation. In addition, loperamide N-oxide has been shown to inhibit the growth of tumor cells and may have potential as a therapeutic agent for cancer treatment. However, it should be noted that rifampicin and other inhibitors can reduce the effectiveness of loperamide N-oxide against cancer cells. Further research is needed to fully understand the potential benefits and limitations of this compound.

Isoquinine is a potent compound with promising anticancer activity. It has been shown to have inhibitory activity against protein kinases, which are enzymes involved in the regulation of cell cycle and proliferation. Isoquinine can act as an inhibitor of kinase inhibitors, leading to a decrease in tumor growth and inducing apoptosis in tumor cells. In addition to its potential as an anticancer agent, Isoquinine has also shown antitumor activity against Alzheimer's disease. This compound is a carboxylic acid that can bind to specific targets within cells and inhibit their function, making it a promising candidate for future drug development. Its unique mechanism of action makes it an attractive target for further study and exploration.

Lactiflorin is a natural compound that has been found to have potent inhibitory effects on cancer cells. This medicinal plant extract is commonly used in Chinese traditional medicine as an anticancer agent. Lactiflorin has been shown to induce cell cycle arrest and promote apoptosis in human cancer cells by inhibiting the activity of protein kinases, which are essential for tumor growth and survival. Additionally, lactiflorin analogs have been developed with even greater potency against cancer cells. In preclinical studies, lactiflorin and its derivatives have demonstrated promising results as potential therapeutic inhibitors for various types of cancers. Furthermore, lactiflorin has also shown potential as a non-invasive biomarker for early detection of certain cancers through analysis of urine samples.

Please enquire for more information about Benzyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about Flupirtine-N2-β-D-glucuronide including the price, delivery time and more detailed product information at the technical inquiry form on this page

Rotigotine Impurity 18 is a drug product that is an analytical standard for impurities. It is a synthetic impurity that is not found in natural sources. Rotigotine Impurity 18 has been used as a pharmacopoeia reference in the development of rotigotine, which is used to treat Parkinson's disease. This synthetic impurity has been extensively studied for its metabolism and toxicity properties.

Atorvastatin is a drug product that is designed for the treatment of dyslipidemia, hypercholesterolemia, and mixed dyslipidemia. It is an impurity in the drug product Atorvastatin EP. Impurity B is a natural metabolite that has been found to have a niche market as an analytical standard for HPLC. The metabolite can be synthesized with high purity and quality standards, which are suitable for use in pharmacopoeia and research and development.

Stafib-2 is an analog inhibitor that has shown potent anticancer activity in human cancer cell lines. It works by inhibiting kinases, which are enzymes that play a key role in regulating cell growth and division. Stafib-2 has been shown to induce apoptosis, or programmed cell death, in Chinese hamster ovary cells and human cancer cells. This drug also inhibits the activity of elastin kinase, a protein that is involved in tumor growth and metastasis. Stafib-2 has potential as a targeted therapy for cancer treatment due to its ability to selectively inhibit specific kinases involved in cancer progression. Its unique mechanism of action makes it a promising candidate for further development as an anticancer agent.

4-Phenybutyl 2-carboxyethylphosphinic acid is used as an analytical standard and has been shown to be a metabolite of other drugs. It is also used as an impurity standard for HPLC, and provides a niche for drug product development.

Lumiflavin 5-oxide is a metabolite of lumiflavin. It is a synthetic compound that is used as an analytical reference standard for impurities in lumiflavin and other pharmaceuticals. Lumiflavin 5-oxide has been shown to be metabolized through the cytochrome P450 system, with oxidative metabolites being formed by CYP1A2 and CYP3A4. Lumiflavin 5-oxide has also been shown to be a competitive inhibitor of NAD+-dependent enzymes such as glycerol kinase, phosphofructokinase, lactate dehydrogenase, alcohol dehydrogenase, and glucose 6-phosphate dehydrogenase.

Please enquire for more information about Loxoprofen methyl-d3 ethyl ester including the price, delivery time and more detailed product information at the technical inquiry form on this page

Solifenacin N-oxide is an anti-cholinergic agent that has been shown to be effective in the treatment of overactive bladder. Solifenacin N-oxide is a prodrug that is hydrolyzed in vivo to solifenacin, its active form. The compound reversibly binds to muscarinic receptors and inhibits the release of acetylcholine. Solifenacin N-oxide has been shown to have low levels of impurities and is highly soluble in water. It was also found to be stable when stored at room temperature for two months. This drug has a high flow rate and moderate retention time, which makes it suitable for reversed-phase liquid chromatography (RPLC). RPLC is a chromatographic technique that separates compounds by size, hydrophobicity, or charge.

Mikimopine is a kinase inhibitor that has shown promising results in the treatment of cancer. It works by inhibiting specific proteins involved in cancer cell growth and survival, leading to apoptosis (cell death) of tumor cells. Mikimopine is an analog of a naturally occurring protein found in human urine and Chinese medicinal herbs. It specifically targets cyclin-dependent kinases, which are enzymes that regulate cell division and proliferation. This drug has shown potent anticancer activity both in vitro and in vivo, making it a promising candidate for further development as an anticancer agent. Its selectivity towards cancer cells makes it a potentially effective therapy with minimal side effects compared to traditional chemotherapy treatments.

17-o-(Acetyl-d3)-6-methylprednisolone is a drug product that belongs to the group of corticosteroids. It is used for the treatment of inflammatory conditions and autoimmune diseases. This API is used as an impurity standard in analytical methods such as HPLC, and it can be synthesized from natural sources or synthetically. 17-o-(Acetyl-d3)-6-methylprednisolone can also be used in R&D for the development of drugs targeting niche markets, such as those with high purity requirements.

Ivermectin is a drug that belongs to the anthelmintic class of drugs. It is active against roundworms, pinworms, and hookworms. Ivermectin has been shown to have an effect on autoimmune diseases such as multiple sclerosis, systemic lupus erythematosus, and rheumatoid arthritis by inhibiting the inflammatory response. The drug has been shown to inhibit matrix metalloproteinases in vitro and in vivo. The matrix effect is seen when the drug binds to proteins in the blood plasma or tissue matrix, where it inhibits their activity. This inhibition prevents the degradation of collagen, which can lead to tissue damage or renal failure. Ivermectin also binds to striatal dopamine receptors and inhibits dry weight gain in animals infected with Ostertagia ostertagi. Ivermectin is given orally in a single dose of 200 micrograms/kg body weight for treatment of intestinal worms (roundworm,

Linagliptin impurity E is a metabolite of the drug Linagliptin. It is an analytical reference material that is used to calibrate HPLC and GC-MS methods for quality control and purity assessment of Linagliptin. This impurity standard is also used for metabolism studies.

Acetylazide is an analog of a compound found in human urine that has shown promising anticancer activity. It is a potent inhibitor of protein kinases, which are enzymes involved in the regulation of cell growth and division. Acetylazide has been shown to induce apoptosis (cell death) in cancer cells, particularly those associated with thyroid cancer. This compound has also been tested in Chinese hamster ovary cells and has demonstrated a high degree of selectivity for tumor cells over normal cells. Acetylazide may be a promising candidate for the development of new anticancer drugs.

Desgadolinium gadoteridol is a contrast agent that is used in magnetic resonance imaging (MRI). It is a gadolinium-based contrast agent that contains an ester linkage. The chelate complex of gadolinium with desgadolinium has been shown to have high water permeability and target tissue affinity, as well as low toxicity. Desgadolinium gadoteridol is used to diagnose inflammatory bowel diseases by determining the thickness of the bowel wall. This agent may also be used to evaluate blood pressure and diagnose hemorrhoids or colorectal polyps.

Aceclofenac ethyl ester is a prodrug of diclofenac. It is a non-steroidal anti-inflammatory drug that alleviates the symptoms of pain, stiffness, and swelling. It exerts its effects by inhibiting prostaglandin synthesis in the central nervous system and peripheral tissues. Aceclofenac ethyl ester has minimal systemic absorption when administered orally, which reduces the risk of side effects such as stomach upset and kidney damage. The pharmacopoeia provides an efficient method for preparing this compound by reacting diclofenac with magnesium stearate in a solvent containing an organic amine or alcohol at temperatures below 50°C (122°F). Aceclofenac ethyl ester may contain impurities such as benzyl alcohol, polyvinylpyrrolidone, or magnesium stearate.

Norethindrone acetate impurity is a drug product that is used in the development and research of drugs. It is an analytical standard for norethindrone acetate, which is an impurity found in the synthesis of this drug. Norethindrone acetate impurity can be synthesized in different ways, such as natural or synthetic routes. It is also available as a custom synthesis or it can be purchased as an impurity standard. This compound's CAS number is 1175129-26-6 and it has a purity level of 99%.

Apigenin 5-o-β-D-glucuronide is a natural compound derived from the Chinese herb scutellaria baicalensis. It has been shown to be effective in reducing pro-inflammatory cytokines and prostate cancer cells. Apigenin 5-o-β-D-glucuronide is one of the many phenolic acids found in plants, which are known for their antioxidant and anti inflammatory properties. The plant metabolizes apigenin 5-o-β-D-glucuronide by conjugating it with glucuronic acid, forming the glucuronide conjugate. The bioactive phenolic compounds in plants are well studied and have been shown to have anticancer properties.