APIs per la ricerca e le impurità

6-Methylene progesterone acetate is a polymerase chain inhibitor that inhibits the synthesis of viral and cellular DNA. It was first isolated from infected cells in tissue culture and has been shown to inhibit the growth of a wide range of viruses, including rabies, herpes simplex, herpes zoster, cytomegalovirus, varicella-zoster virus, and vesicular stomatitis virus. 6MPAA also blocks the production of gene products in mammalian cells by preventing RNA synthesis. This drug can be used as an antiviral agent for treatment of enteritis caused by rotavirus infection. 6MPAA binds to gp2 protein on the surface of virus particles and prevents this protein from interacting with polyclonal antibodies or monoclonal antibodies to prevent antibody response.

Tirzepatide impurities.

Atorvastatin epoxydione impurity (EPI) is a heptanoic, hydrate, diastereoisomer, racemic mixture, enantiomer and impurity of Atorvastatin. The EPI has been minimized in the formulation process by using a novel synthesis route that employs a chiral pyrrole derivative as an intermediate. This minimization has allowed for the elimination of the tautomer and other impurities present in the original compound.

N-[[2'-(2H-Tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-valine methyl ester is a synthetic compound used as an HPLC standard. It is also used in the development of new drugs to study the metabolism of these drugs and their metabolites. N-[[2'-(2H-Tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-valine methyl ester can be synthesized from 2-[(2H)-tetrazol-5-yl][1,1'-biphenyl]-4-(phenylamino)propanenitrile and L -valine methyl ester. It is soluble in ethyl acetate, chloroform and methanol. N-[2'(2H)-tetrazol-[5' (phenylamino)

Daunorubicin metabolite

Everolimus is an immunosuppressant that belongs to the group of rapamycin analogs. It is a synthetic drug and has been shown to be effective in preventing rejection of transplanted organs, such as kidneys, livers, and hearts. Everolimus O-ethyl impurity is a metabolite of everolimus that can be used as a standard for HPLC analysis. The CAS number for this impurity is 1704711-12-5. Everolimus O-ethyl impurity can also be used as a reference material in metabolism studies.

Cetirizine is a drug product that is metabolized to cetirizine propanediol ester. This impurity has been identified in the drug and is not expected to cause any adverse effects in humans. Cetirizine propanediol ester can be synthesized and purified through high-purity, analytical, and natural methods. The pharmacopoeia defines cetirizine propanediol ester as a metabolite of cetirizine. It can also be used as an impurity standard for HPLC analysis.

2-Carboxybenzoyl amlodipine is a metabolite of the antihypertensive drug amlodipine. It is a white crystalline solid that is soluble in water. 2-Carboxybenzoyl amlodipine can be used as an impurity standard for HPLC analyses, and as an analytical standard for the determination of amlodipine in human plasma.

Naltrexone impurity E is an analytical standard that is used to calibrate high-performance liquid chromatography (HPLC) instruments. This substance is a natural metabolite of naltrexone, which is an opioid receptor antagonist, and has the chemical name of 4-hydroxy-3-methoxy-N-(5α,6β)-dimethyl-2-[(1R)-1-(3-methyloxetan-3-yl)piperidin-4-yl] benzeneacetamide. Naltrexone impurity E is a pharmacopoeia grade compound that can be used in the synthesis of drug products. Custom synthesis and natural or synthetic sources are available.

Cetirizine Impurity B is a custom synthesis impurity. It is a product of the metabolism of cetirizine, an anti-allergic drug. Cetirizine Impurity B is used as an impurity standard for drug development and analytical HPLC studies. It has been assigned CAS number 113740-61-7 by the Chemical Abstracts Service. The purity of this compound is greater than 99%.

Erythromycin impurity M is a natural, API impurity (impurity standard) that is a metabolite of erythromycin. It has been synthesized as a high purity HPLC standard to meet the requirements of pharmacopoeia and drug development. Erythromycin impurity M is an analytical reference material with CAS number 528-73-2.

Rotigotine Impurity 7 is an impurity that has been identified in the synthesis of rotigotine. Rotigotine Impurity 7 is a synthetic compound with a CAS number of 1229620-82-9. It is intended for use as an analytical standard and as a component in the manufacture of rotigotine, which is indicated for the management of Parkinson's disease. This product has not been tested in animals or humans, and it should be handled with care.

Bis-[5-[(dimethylamino)methyl]furan-2-yl]methane is a synthetic compound with the CAS number 16864-73-6. It is used in pharmacological studies and drug development. The purity of this material is greater than 99%.

2-[[[(4-Methoxypropoxy)-3-methyl-2-pyridinyl]methyl]sulfonyl]-1H-benzimidazole is a protonated sulfonamide that is used as an analytical method to detect the presence of other drugs in human liver tissue. It has been shown to inhibit the activity of cytochrome P450 3A4 (CYP3A4), one of the enzymes responsible for metabolizing many drugs. Bromoenol lactone and powder diffraction spectrum are two additional analytical methods that can be used to detect 2-[([(4-methoxypropoxy)-3-methyl-2-pyridinyl]methyl]sulfonyl]-1H-benzimidazole.

Chlorthalidone impurity G is a synthetic, high purity, pharmacopoeia grade impurity standard for chlorthalidone. It is a metabolite of the drug and can be found in the urine of patients taking this medication. Chlorthalidone impurity G is used for metabolism studies, as it may have an effect on the excretion of other drugs. Research and Development

Remdesivir impurity 10 is a synthetic chemical compound that has been synthesized for research and development. It is an impurity standard of remdesivir, which is not present in any drug product. The purity of this product is high, and it can be used as a pharmacopoeia or drug development standard. It can also be used as an analytical standard to measure the concentration of metabolites in animal studies or metabolism studies.

22-Oxo-vincaleukoblastine 6'-oxide is a synthetic drug with no known clinical use. It is an impurity of the vinca alkaloid drug vinblastine and may be found in small amounts in other vinca alkaloid drugs. 22-Oxo-vincaleukoblastine 6'-oxide is a metabolite of the vinca alkaloids, which are used as anticancer drugs. This substance has been shown to inhibit the metabolism of some cancer cells, leading to increased cell proliferation.

Terbutaline Impurity D is a synthetic drug with the CAS number 94109-61-2. This product has been developed as an impurity standard for Terbutaline, which is a drug product that has been approved by the United States Pharmacopoeia (USP). Terbutaline Impurity D can be used to study the metabolism of Terbutaline in animals. It is also used to develop new drugs by chemists and other scientists.

11-(1-Piperazinyl)dibenzo[b,f][1,4]thiazepine hydrochloride is a drug product that is used as an impurity standard in the manufacture of 11-aminoundecanoic acid. It is also used to study the metabolism of this compound. This drug product is not intended for use in humans or animals.

Memantine impurity IV is a hydrolysis product of memantine. It appears as a white to off-white powder and has a molecular weight of 198.1 g/mol. Memantine impurity IV is an intermediate in the production of memantine and is therefore not used for any other purpose. The compound contains hydroxy groups, hydroxy, alcohols, and bridgehead groups which are efficient at hydrolyzing to form amino acids.

Clarithromycin EP Impurity K is an impurity standard for Clarithromycin in the form of a crystalline white powder. It is a synthetic compound which has been used as a drug product and as an analytical standard. This compound can be synthesized from erythromycin A, but it is not active against bacteria. Clarithromycin EP Impurity K has been shown to have metabolite properties in animals and humans, including metabolism studies with HPLC standards.

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This compound is a research and development impurity standard. It is synthesized in accordance with the pharmacopoeia, and it is an API impurity. It is also used as a metabolite standard for drug development and metabolism studies. This compound has been tested in HPLC standards.

Tirzepatide Impurity

Natriuretic hormone; induces uterine contraction and lactation

Trazodone Hydrochloride Impurity G is a synthetic compound that is an impurity found in Trazodone Hydrochloride, CAS No. 77893-17-6. This compound has the following physical properties: MW = 284.27, mp = 227-229°C, [α] D = -33.5° (c 1.0 in water), and UV max (λ max ) = 228 nm. It has been shown that this compound is not metabolized by human enzymes and is found to be natural. It can be used as a standard for HPLC analysis of Trazodone Hydrochloride Impurities A-F with the following retention times: 8.7 min for Impurity A, 9.2 min for Impurity B, 9.9 min for Impurity C, 10.4 min for Impurity D, 11.1 min for Impurity E, and 12.3 min for Impurity F.BR>BR

9-Oxo azithromycin B is a metabolite of azithromycin. It is an analytical standard for the HPLC analysis of azithromycin and its metabolites. 9-Oxo azithromycin B has been shown to bind to the ribosomes of bacteria, and inhibit protein synthesis. This drug also has antibiotic activity against Mycobacterium avium and Mycobacterium tuberculosis. 9-Oxo azithromycin B can be used in niche research or as an API impurity.br>
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Rifaximin Impurity 1 is a synthetic impurity standard for Rifaximin. It is a metabolite of rifaximin and is used in research and development to test the purity of drug products. It has a molecular weight of 314.2 g/mol and molecular formula C9H16N4O4S. This product is not manufactured by or for the original equipment manufacturer (OEM).

Risedronate sodium hydrate is a polymorphic, water-soluble salt of risedronate. It has been used in the treatment of osteoporosis and Paget's disease of bone. Risedronate sodium hydrate binds to calcium ions in the body and prevents them from being deposited in bone tissue. This drug also cross-links collagen fibers in the bone matrix, which increases mineralization and decreases the risk of fracture by strengthening the bones. The monosodium salt form of risedronate is soluble in water and is used as an analytical reagent for determining ionic strength or pH. It has been shown to inhibit ionotropic gelation, which may be due to its polyphosphoric acid content. Risedronate sodium hydrate is a polymorphic, water-soluble salt of risedronate that has been used in the treatment of osteoporosis and Paget's disease of bone. Risedronate sodium hyd

N-(5-Aminopentyl) methotrexate amide is a fluorescent probe that is used to study the transport of drugs across cell membranes. It binds to the plasma membrane of cells and can be visualized with a fluorescence microscope. N-(5-Aminopentyl) methotrexate amide has been shown to bind to leukemia cells in murine leukemia models. It has a high affinity for drug-resistant cells, which makes it useful for studying drug resistance mechanisms. This probe can be used at nanomolar concentrations for imaging studies, as well as for measuring the uptake of drugs into cancer cells by flow cytometry.

Rabeprazole is a proton pump inhibitor that suppresses the production of stomach acid by blocking the H+/K+ ATPase enzyme. It is used for the treatment of gastroesophageal reflux disease, peptic ulcers, and Zollinger-Ellison syndrome. Rabeprazole has been shown to be more effective than omeprazole in reducing gastric acid secretion in two-way crossover studies. Rabeprazole also has been shown to inhibit the growth of antibiotic-resistant strains of bacteria. In addition, rabeprazole binds to metal ions like iron and copper, which may affect its pharmacokinetics and efficacy. This drug is currently being investigated as an analytical method for determination of proton pump inhibitors in human serum and urine samples by electrochemical impedance spectroscopy (EIS).

Pantoprazole sulfide N-oxide is a metabolite of pantoprazole, which is a proton pump inhibitor used to reduce stomach acid production. Pantoprazole sulfide N-oxide is an impurity in pantoprazole that can be detected by HPLC. It has been shown to have about the same biological activity as pantoprazole when given orally.

Esomeprazole is a proton pump inhibitor used to treat gastroesophageal reflux disease and other conditions where there is too much stomach acid. It is available as a capsule or tablet in doses of 20, 40, and 60 mg. Esomeprazole inhibits the production of gastric acid by blocking the hydrogen/potassium adenosine triphosphate (H+/K+ ATPase) enzyme system at the secretory surface of the gastric parietal cells. Omeprazole is an acidic drug that blocks the H+/K+ ATPase enzyme system. The two drugs have been compared in two-way crossover studies using healthy volunteers who were given omeprazole magnesium for one week followed by esomeprazole sodium for another week. There was no difference in their effect on acid secretion or on heartburn relief. The plasma concentrations of both drugs increased with increasing dose, but there was no significant difference between them in terms of either

Olsalazine sodium impurity D is a natural substance that is present as an impurity in the drug Olsalazine sodium. It is used as an analytical standard for Olsalazine sodium and its metabolites, which are involved in drug development. The purity of this substance can be customized by our research and development team. This product has CAS number 93964-55-7 and is available at a reasonable price.

4-(2-Methoxyethyl)phenol is a synthetic compound that is an antihypertensive agent. It is used to reduce high blood pressure, which may be due to its ability to block the action of angiotensin II, a potent vasoconstrictive hormone, by binding with its receptor. 4-(2-Methoxyethyl)phenol has been shown to be more potent than metoprolol succinate and less toxic than hydroxylated compounds such as propranolol in pharmacokinetic studies. In addition, 4-(2-Methoxyethyl)phenol has been found to have a low risk of congestive heart failure. The industrial process for this substance involves the reaction of hydrochloric acid with phenol in the presence of a catalyst such as aluminium chloride or zinc chloride.

Ethyl 3-aminopyrazole-4-carboxylate is an anticancer drug that inhibits the growth of cancer cells by inhibiting protein synthesis. It has been shown to inhibit the activity of dpp-iv and pde5, which are enzymes involved in cellular proliferation. Ethyl 3-aminopyrazole-4-carboxylate has also been shown to have antiinflammatory properties, which may be due to inhibition of prostaglandin synthesis.
Ethyl 3-aminopyrazole-4-carboxylate is a multinuclear compound that reacts with nitrogen atoms from the pyrazoles to form a stable molecule. Dimethylformamide is used as a solvent for this reaction. The synthesis of ethyl 3-aminopyrazole-4-carboxylate starts with acetylation, which converts the carboxylic acid group into an acetic acid group. The acetic acid group reacts with ammonia and hydrogen cyan

Dehydroxy bisoprolol is an impurity of the drug Bisoprolol that is used to make the drug product Metoprolol. It is a metabolite of Bisoprolol, which is produced by the liver after metabolism and excretion. Dehydroxy bisoprolol has been detected in plasma, urine, feces, and breast milk. The pharmacological effects of Dehydroxy bisoprolol have not been studied.

Di-2-thienylmethanone is a pyrazole with an activation energy of about 10.5 kcal/mol. It has been found to be toxic and can cause cell lysis. This molecule has been used in the synthesis of a number of drugs, including thiopental, a barbiturate that is used as an anaesthetic. Di-2-thienylmethanone is also the precursor for the synthesis of fluoroquinolones, which are potent antibacterial agents. The Friedel-Crafts reaction is one way this molecule is synthesized, and it involves the addition of an alkyl halide to an unsaturated double bond. This reaction is named after Charles Friedel and James Crafts who first discovered it in 1877.

Dapagliflozin Impurity 4 is a research and development impurity standard for the drug Dapagliflozin. Dapagliflozin Impurity 4 is a white crystalline solid with a molecular weight of 646.5 and an empirical formula of C20H22N2O2. It is soluble in water, methanol, ethanol, and acetonitrile. The compound has a melting point of 181°C with decomposition and a boiling point of 254°C at 760 mm Hg. It is not oxidizable under aerobic conditions and does not react with acid or alkali to form any ionizable species.

3-(N-Phenyl-N-methyl)aminoacrolein is a hydrophobic compound that has been shown to reversibly bind to serum albumin. This binding leads to a decrease in the lipid content of lipoproteins and a decrease in the rate of their metabolism. These effects are mediated by hydrophobic interactions with the hydrophobic regions of serum albumin. 3-(N-Phenyl-N-methyl)aminoacrolein also interacts with human serum albumin, which is involved in lipid transport and metabolism, and can be used as a contrast agent for X-ray diffraction studies.

Betamethasone EP Impurity G is an analytical impurity that is found in the drug product Betamethasone EP. It is also a natural, synthetic, and custom synthesis impurity that has been manufactured to be an impurity standard. Betamethasone EP Impurity G has a CAS number of 85700-75-0 and is a niche HPLC standard for research and development purposes. This high purity impurity may be synthesized from other chemical compounds or created synthetically.

N-Methyl formoterol fumarate is a drug product for the treatment of asthma and chronic obstructive pulmonary disease. It is a synthetic drug that has been approved by the FDA, but is also a metabolite of terbutaline. Metabolism studies have shown that N-methyl formoterol fumarate is an impurity in Terbutaline sulfate and Terbutaline hydrochloride. This drug is not active against bacteria, but may be used as an analytical standard to measure the purity of other drugs.