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APIs per la ricerca e le impurità

APIs per la ricerca e le impurità

I principi attivi farmaceutici (API) sono le sostanze nei farmaci responsabili dei loro effetti terapeutici. In questa sezione troverai una vasta gamma di API destinati all'uso in ricerca. Questi composti sono essenziali per lo sviluppo, il test e la validazione di nuove formulazioni farmaceutiche. Presso CymitQuimica, offriamo API di alta qualità per supportare la ricerca nella scoperta e nello sviluppo di farmaci.

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  • Xanthoxin

    CAS:

    Xanthoxin is a medicinal compound with potent anticancer properties. It has been shown to induce apoptosis, or programmed cell death, in cancer cells. Xanthoxin has been tested in various cancer cell lines, including Chinese and human cells, and has demonstrated strong inhibitory effects on the tumor cycle. This compound works by inhibiting kinases and other proteins involved in cancer cell growth and proliferation. Xanthoxin is also known to be an inhibitor of certain urinary proteins that are associated with cancer progression. Overall, Xanthoxin shows great potential as a natural product for the development of novel anticancer therapies.

    Formula:C15H22O3
    Purezza:Min. 95%
    Peso molecolare:250.33 g/mol

    Ref: 3D-IAA06607

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  • N-Desbispropyl-N-pentyl-2-methyl ropinirole

    CAS:

    N-Desbispropyl-N-pentyl-2-methyl ropinirole is an analytical reference standard. This product is a high purity, drug development, and API impurity. It is a CAS No. 249622-60-4 and has a niche, drug product, and impurity standard. This item is for Research and Development, High purity, Drug development, API impurity, HPLC standard, CAS No. 249622-60-4, niche, drug product, Impurity standard, Metabolite, pharmacopoeia Custom synthesis of natural or synthetic origin.

    Formula:C16H24N2O
    Purezza:Min. 95%
    Peso molecolare:260.37 g/mol

    Ref: 3D-ZJA62260

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  • Alpha-amino-4-octylbenzenebutanoic acid

    CAS:

    Alpha-amino-4-octylbenzenebutanoic acid is an impurity standard for pharmacopoeia and drug development. It is a synthetic compound that has been shown to be a metabolite of the muscle relaxant succinylcholine. Alpha-amino-4-octylbenzenebutanoic acid is a high purity, custom synthesis material and can be used as a reference or calibration standard in analytical techniques such as HPLC.

    Formula:C18H29NO2
    Purezza:Min. 95%
    Peso molecolare:291.40 g/mol

    Ref: 3D-WYA82019

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  • (Z)-Fluvoxamine - EP

    Prodotto controllato
    CAS:

    (Z)-Fluvoxamine-EP is a drug product that is used as an analytical standard. It is a synthetic metabolite of fluvoxamine, which is a drug used for the treatment of depression. The synthesis of (Z)-fluvoxamine-EP is based on the asymmetric synthesis of fluvoxamine and the use of chiral chromatography to purify the product. This synthetic process allows for the production of high-purity (Z)-fluvoxamine-EP with a purity greater than 99%.

    Formula:C15H21F3N2O2
    Purezza:Min. 95%
    Peso molecolare:318.33 g/mol

    Ref: 3D-IF23523

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  • 2-((2-Methyl-1-(propionyloxy)propoxy)(4-phenylbutyl)phosphoryl)acetic acid

    CAS:
    2-((2-Methyl-1-(propionyloxy)propoxy)(4-phenylbutyl)phosphoryl)acetic acid (KZPBA) is a zoonotic antibiotic that has been shown to be active against agalactiae. It is a prodrug, which is metabolized to the active form, KZPBA, in humans and other mammals. The mechanism of action of KZPBA is not yet known; however, it has been hypothesized that its activity may be due to inhibition of DNA gyrase and topoisomerase IV. This drug has also been shown to have an effect on mastitis in dairy cows.
    Formula:C19H29O6P
    Purezza:Min. 95%
    Peso molecolare:384.4 g/mol

    Ref: 3D-IM27637

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  • (2S)-2-Amino-3-methoxy-N-(phenylmethyl)propanamide

    CAS:

    Please enquire for more information about (2S)-2-Amino-3-methoxy-N-(phenylmethyl)propanamide including the price, delivery time and more detailed product information at the technical inquiry form on this page

    Formula:C11H16N2O2
    Purezza:Min. 95%
    Peso molecolare:208.26 g/mol

    Ref: 3D-ZTA53478

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  • Fonofos

    CAS:

    Fonofos is a potent inhibitor that has been shown to induce apoptosis in Chinese hamster ovary cells. It is also known to inhibit chitin kinase, a protein that plays an important role in the biosynthesis of chitin, which is essential for the formation of cell walls in fungi and insects. Fonofos has medicinal properties and has been studied as a potential anticancer agent due to its ability to inhibit tumor growth. In vitro studies have shown that Fonofos can inhibit the growth of human cancer cells by inhibiting heparin-binding proteins. Additionally, it has been found to have inhibitory effects on several other enzymes involved in cancer development and progression. Although not approved for use in humans, Fonofos may hold promise as a therapeutic agent for the treatment of certain cancers.

    Formula:C10H15OPS2
    Purezza:Min. 95%
    Peso molecolare:246.3 g/mol

    Ref: 3D-AAA94422

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  • N-Desmethyl trimeprazine

    CAS:

    N-Desmethyl trimeprazine is a synthetic compound, which is an impurity of the drug product. It is not active and does not possess any biological activity. It is a metabolite of the parent drug, Trimeprazine. N-Desmethyl trimeprazine has been studied for its pharmacological properties and metabolism in the body, but no conclusive results have been found. The chemical structure and purity of N-Desmethyl trimeprazine are not listed in the USP or BP. This compound can be custom synthesized on request.

    Formula:C17H20N2S
    Purezza:Min. 95%
    Peso molecolare:284.40 g/mol

    Ref: 3D-XAA73204

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  • Elsinochrome A

    CAS:

    Elsinochrome A is a drug product that has not been approved for human use. It belongs to the class of drugs called natural products and has not been synthesized. Elsinochrome A is a metabolite of erythromycin, which is produced by the fungus Elsinoë sp. The chemical structure of this natural product was determined using spectral analysis, and it was found to be similar to the antibiotic erythromycin. Elsinochrome A has shown promising results in pharmacological studies as a potential drug candidate for tuberculosis treatment because it inhibits bacterial growth by binding to DNA-dependent RNA polymerase, thereby preventing transcription and replication.

    Formula:C30H24O10
    Purezza:Min. 95%
    Peso molecolare:544.50 g/mol

    Ref: 3D-ZAA56867

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  • N’-(4-Acetylaminophenyl)-N,N-dimethylacetamidine

    CAS:
    N’-(4-Acetylaminophenyl)-N,N-dimethylacetamidine is a drug product that is used in the development of new drugs. It has high purity, analytical grade and natural origin. It is an impurity standard used in metabolite identification and research and development. The CAS number for this compound is 1358054-66-6.
    Formula:C12H17N3O
    Purezza:Min. 95%
    Peso molecolare:219.28 g/mol

    Ref: 3D-IEC05466

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  • Doxorubicin Impurity 15

    CAS:

    Doxorubicin impurity 15 is a natural product that is used as an analytical reference standard in pharmacopoeia. It has been synthesized for use in drug development and research and development, and is available as a high-purity HPLC standard. Doxorubicin impurity 15 has a CAS number of 131086-18-5.

    Formula:C31H38BrNO11
    Purezza:Min. 95%
    Peso molecolare:680.54 g/mol

    Ref: 3D-ID163220

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  • tert-Butyl 4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazine-1-carboxylate

    CAS:
    tert-Butyl 4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazine-1-carboxylate is an impurity that is found in the production of tert-butyl 4-(4,5,6,7,8,9,10-hexahydrobenzo[a]pyrido[1,2:4,3]triazin-2(3H)-yl)piperazine-1 carboxylate. It has been used as a reference standard for HPLC. This compound is not active when administered orally and does not exhibit any pharmacological activity.
    Formula:C19H27N5O4
    Purezza:Min. 95%
    Peso molecolare:389.4 g/mol

    Ref: 3D-KAC93966

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  • 6-o-Desmethyl moxonidine

    CAS:

    6-O-Desmethyl moxonidine is a drug product that is a metabolite of the parent compound, moxonidine. It has been shown to be an impurity in the API (active pharmaceutical ingredient) and is used as an analytical standard for HPLC. 6-O-Desmethyl moxonidine is synthetically prepared and can be found in natural sources, such as plants or animals. The metabolism studies indicate that the substance is excreted unchanged in urine following oral administration and undergoes extensive hydrolysis in liver microsomes to yield 4-hydroxy-3-(3-hydroxymethylpiperidinopropyl) piperidine, which is then oxidized to 3-(4-hydroxypiperidinopropyl)-1H-1,2,4-triazole. This product may cause skin irritation.

    Formula:C8H10ClN5O
    Purezza:Min. 95%
    Peso molecolare:227.65 g/mol

    Ref: 3D-CPA45733

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  • Enalaprilat tert-butyl ester

    CAS:

    Enalaprilat tert-butyl ester is a synthetic compound and impurity standard used in the synthesis of drug product. Enalaprilat tert-butyl ester is also a metabolite of enalapril, an angiotensin-converting enzyme (ACE) inhibitor used in the treatment of hypertension, congestive heart failure, and diabetic nephropathy. Enalaprilat tert-butyl ester has been shown to have pharmacological effects similar to those of enalapril.

    Formula:C22H32N2O5
    Purezza:Min. 95%
    Peso molecolare:404.5 g/mol

    Ref: 3D-ZBB79629

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  • 2-[[4-(2-Pyridylsulfamoyl)phenyl]azo]hydroxybenzene

    CAS:

    2-[[4-(2-Pyridylsulfamoyl)phenyl]azo]hydroxybenzene is an impurity found in sulfasalazine. It is a metabolite that is formed by the P450 system in the liver. The metabolic process of 2-[[4-(2-Pyridylsulfamoyl)phenyl]azo]hydroxybenzene has been studied in detail and has been shown to be a major contributor to the pharmacokinetic profile of sulfasalazine. This substance also exhibits antimicrobial activity and inhibits the growth of bacteria, fungi, and viruses.

    Formula:C17H14N4O3S
    Purezza:Min. 95%
    Peso molecolare:354.38 g/mol

    Ref: 3D-IP27340

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  • 2-(4-Formylphenyl)propionic acid - Racemic

    CAS:

    2-(4-Formylphenyl)propionic acid is a racemic mixture of 2-formylphenylacetic acid and 4-formylphenylacetic acid. This compound is used in the treatment of bacterial infections and inflammation. It is an organic solution that can be injected, administered orally, or applied topically. The 2-(4-formylphenyl)propionic acid has been shown to have anti-inflammatory properties, but also has side effects such as skin irritation when it is applied topically. This drug can also cause nausea, vomiting, and diarrhea when administered orally.

    Formula:C10H10O3
    Purezza:Min. 95%
    Colore e forma:White Powder
    Peso molecolare:178.18 g/mol

    Ref: 3D-IF27430

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  • Minocycline EP Impurity H

    CAS:

    Please enquire for more information about Minocycline EP Impurity H including the price, delivery time and more detailed product information at the technical inquiry form on this page

    Formula:C23H25N3O7
    Purezza:Min. 95%
    Peso molecolare:455.47 g/mol

    Ref: 3D-IM183785

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  • Ethyl 2-methoxy-5-sulfamoylbenzoate

    CAS:

    Ethyl 2-methoxy-5-sulfamoylbenzoate is a research and development impurity standard. It is a white to off-white crystalline solid that is soluble in water. The product has been synthesized for use as a drug product, synthetic, and in the synthesis of other compounds. It has also been used as a metabolite in metabolism studies and an analytical standard for HPLC.

    Formula:C10H13NO5S
    Purezza:Min. 95%
    Peso molecolare:259.28 g/mol

    Ref: 3D-IE140268

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  • N-(4-Amino-6,7-dimethoxyquinazol-2-yl)-N-methylpropylenediamine formamide hydrochloride

    CAS:

    N-(4-Amino-6,7-dimethoxyquinazol-2-yl)-N-methylpropylenediamine formamide hydrochloride is an impurity in the synthesis of N-(4-amino-6,7-dimethoxyquinazol-2-yl)-N'-methylpropylenediamine formamide hydrochloride. It is a white solid that can be used as an analytical reference standard for HPLC. It has been detected in the urine of people taking this drug and can be used to identify the presence of this drug in urine samples.

    Formula:C14H17N5O2·HCl
    Purezza:Min. 95%
    Peso molecolare:323.78 g/mol

    Ref: 3D-IA156915

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  • Sacubitril methyl ester

    CAS:

    Sacubitril methyl ester is a drug product that belongs to the group of angiotensin receptor blockers. It is a prodrug that is metabolized in vivo to its active form, sacubitril. Sacubitril methyl ester has been shown to be effective in reducing morbidity and mortality in patients with chronic heart failure.

    Formula:C23H27NO5
    Purezza:Min. 95%
    Colore e forma:Powder
    Peso molecolare:397.47 g/mol

    Ref: 3D-IS181150

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  • 9-Methylamino minocycline

    CAS:

    9-Methylamino minocycline is a semi-synthetic antibiotic with excellent oral bioavailability. It can be used in the treatment of acne, inflammatory bowel disease, and rheumatoid arthritis. 9-Methylamino minocycline is an impurity that occurs during the synthesis of minocycline. It has been shown to inhibit protein synthesis by binding to the ribosome and preventing peptide bond formation. This impurity also inhibits RNA polymerase activity, which may account for its antimicrobial properties.

    Formula:C24H30N4O7
    Purezza:Min. 95%
    Peso molecolare:486.52 g/mol

    Ref: 3D-HZA40273

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  • CPI 0610

    CAS:

    CPI 0610 is a medicinal compound that acts as a potent inhibitor of protein phosphorylation. It has been shown to inhibit the cell cycle and promote apoptosis in Chinese hamster ovary cells. CPI 0610 is an effective inhibitor of kinase activity in cancer cells, leading to decreased tumor growth and increased survival rates. In preclinical studies, CPI 0610 has demonstrated efficacy against a wide range of cancers, including breast, prostate, and lung cancer. This inhibitor has also been shown to be effective in human cancer cell lines, making it a promising candidate for future cancer therapies.

    Formula:C20H18ClN3O3
    Purezza:Min. 95%
    Peso molecolare:383.8 g/mol

    Ref: 3D-VYC72614

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  • Alloc bromoridane

    CAS:

    Alloc bromoridane is a drug product that contains the active ingredient bromoridane. Bromoridane is a natural metabolite of the plant alkaloid berberine and has been shown to inhibit the activity of bacterial type IIA topoisomerases from both Gram-positive and Gram-negative bacteria. The chemical name for Alloc bromoridane is 2-[2-(4-bromobenzoyl)phenyl]dihydropyrimidine, and it has CAS number 117348-70-6. Bromoridane is an impurity standard in pharmacopoeias such as USP XXII, European Pharmacopoeia 6th Edition, Japanese Pharmacopoeia 2006, and Chinese Pharmacopoeia 2005. Alloc bromoridane is used in research and development for pharmaceuticals or as an analytical reference material.

    Formula:C13H20BrNO4
    Purezza:Min. 95%
    Peso molecolare:334.21 g/mol

    Ref: 3D-SEA34870

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  • 9-(1,3-Dioxolan-2-ylmethyl)-3,9-dihydro-1,3-dimethyl-1H-purine-2,6-dione

    CAS:

    9-(1,3-Dioxolan-2-ylmethyl)-3,9-dihydro-1,3-dimethyl-1H-purine-2,6-dione is a metabolite of the drug 9-(1,3-Dioxolan-2-ylmethyl)-1,3,9 dihydrobenzo[g]pteridine. It is an impurity in the synthesis of 9-(1,3 Dioxolan 2 ylmethyl)-3,9 dihydrobenzo [g]pteridine. The purity of this compound is > 99%, with a melting point range of 233 to 235 °C and a molecular weight of 244.24 g/mol. It is soluble in methanol and acetonitrile. This compound has been characterized by IR spectroscopy (ATR), 1H NMR (400 MHz) spectroscopy (CDCl 3 ), and mass spectrometry (HRMS

    Formula:C11H14N4O4
    Purezza:Min. 95%
    Peso molecolare:266.25 g/mol

    Ref: 3D-ZWB28918

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  • Levofloxacin carboxylic acid

    CAS:

    Levofloxacin is a synthetic molecule with an asymmetric carbon atom in its heterocycle. It is synthesized by reacting chloroform with 2-fluoro-5-nitrobenzaldehyde, which reacts further with sodium hydroxide and hydrochloric acid to form the levofloxacin carboxylic acid. Impurities can be found in the reaction product due to chlorine atoms that are formed during the synthesis. The amount of impurities present in the final product can be determined using a titration method or through HPLC analysis. Levofloxacin has been shown to be effective against methicillin-resistant Staphylococcus aureus (MRSA) and Clostridium perfringens, although is not active against acid-fast bacteria such as Mycobacterium tuberculosis or Mycobacterium avium complex.

    Formula:C13H9F2NO4
    Purezza:Min. 95%
    Colore e forma:Powder
    Peso molecolare:281.21 g/mol

    Ref: 3D-IL24882

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  • 6-Desmethyl-6-methylhydroxy etoricoxib N1-oxide

    CAS:

    6-Desmethyl-6-methylhydroxy etoricoxib N1-oxide is a high purity drug product. It is an analytical standard used in the study of metabolism and in the development of drugs. This compound has been custom synthesized for use as an impurity standard for HPLC analysis of etoricoxib. 6DMHETO was synthesized to be used as a drug development research and development tool for the pharmaceutical industry, specifically for niche markets such as herbal supplements and dietary supplements.

    Formula:C18H15ClN2O4S
    Purezza:Min. 95%
    Peso molecolare:390.80 g/mol

    Ref: 3D-VXA39408

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  • cis-Tadalafil

    CAS:

    Cis-Tadalafil is a potent inhibitor of phosphodiesterase 5, which is used to treat erectile dysfunction (ED) and primary pulmonary hypertension (PPH). It works by increasing blood flow to the penis, allowing men with ED to achieve and maintain an erection. Cis-Tadalafil is also used to treat symptoms of prostatic hyperplasia (enlarged prostate) in men. This drug has been shown to be effective in treating PPH by reducing pulmonary arterial pressure and improving exercise capacity. Cis-Tadalafil belongs to the carboline class of drugs and is a phosphodiesterase 5 inhibitor that selectively inhibits cGMP-specific phosphodiesterase type 5 (PDE5). This drug has been shown to be highly effective in treating both ED and PPH with minimal side effects.

    Formula:C22H19N3O4
    Purezza:Min. 95%
    Colore e forma:White/Off-White Solid
    Peso molecolare:389.4 g/mol

    Ref: 3D-FT27987

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  • (S)-Rabeprazole sodium

    CAS:

    (S)-Rabeprazole sodium is an anticancer drug that acts as a kinase inhibitor. It is an analog of Rabeprazole and has been shown to inhibit the growth of cancer cells in vitro and in vivo. (S)-Rabeprazole sodium inhibits the activity of kinases, which are enzymes that play a key role in cell signaling pathways. This inhibition leads to apoptosis, or programmed cell death, in cancer cells. (S)-Rabeprazole sodium has been tested against various types of cancer, including Chinese hamster ovary cells and tumor xenografts in mice. It has also been shown to inhibit elastin degradation, which is important for preventing metastasis of cancer cells. (S)-Rabeprazole sodium may be a promising candidate for the development of new anticancer drugs that target specific kinases and proteins involved in cancer cell growth and survival.

    Formula:C18H21N3O3S•Na
    Purezza:Min. 95%
    Peso molecolare:382.43 g/mol

    Ref: 3D-IR183125

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