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APIs per la ricerca e le impurità

APIs per la ricerca e le impurità

I principi attivi farmaceutici (API) sono le sostanze nei farmaci responsabili dei loro effetti terapeutici. In questa sezione troverai una vasta gamma di API destinati all'uso in ricerca. Questi composti sono essenziali per lo sviluppo, il test e la validazione di nuove formulazioni farmaceutiche. Presso CymitQuimica, offriamo API di alta qualità per supportare la ricerca nella scoperta e nello sviluppo di farmaci.

Sottocategorie di "APIs per la ricerca e le impurità"

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  • 7-Chloro-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid ethyl ester

    CAS:
    <p>7-Chloro-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid ethyl ester is a synthetic compound that has not been evaluated in humans. Studies have shown that the drug can be hydrolyzed to 7-chloro-6-fluoroquinoline 1,1′-(ethylenedioxy)bis(ethane), which is an impurity of norfloxacin. The ethyl esters of 7-chloroquinoline are also known to condense with formaldehyde and hydrolyze to 7-chloroquinolinic acid. This product may contain solvents such as acetone, chloroform, and alcohols that are used during the synthesis process. Decarboxylation of the drug occurs when it is heated at high temperatures in the presence of a catalyst, such as pyridine or sodium methoxide. It decarboxyl</p>
    Formula:C12H9ClFNO3
    Purezza:Min. 95%
    Peso molecolare:269.65 g/mol

    Ref: 3D-ADA07315

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  • aR453588

    CAS:
    <p>aR453588 is a human analog of Voriconazole, which has been found to have anticancer properties. This compound is a kinase inhibitor that works by inducing apoptosis in cancer cells. It has been shown to be effective against various types of tumors, including those resistant to other inhibitors. aR453588 also inhibits the growth of cancer cells by blocking protein synthesis and cell division. This compound is derived from cellulose and can be detected in urine samples after administration. Overall, aR453588 shows great promise as a potential treatment for cancer.</p>
    Formula:C25H25N7O2S2
    Purezza:Min. 95%
    Peso molecolare:519.6 g/mol

    Ref: 3D-QSB60900

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  • Tadalafil spiro-urethane impurity (EP impurity F)

    CAS:
    <p>Please enquire for more information about Tadalafil spiro-urethane impurity (EP impurity F) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>
    Formula:C22H19N3O6
    Purezza:Min. 95%
    Peso molecolare:421.4 g/mol

    Ref: 3D-IT183411

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  • 3-Dodecenal

    CAS:
    <p>3-Dodecenal is a human analog that has been studied for its potential anticancer properties. It has been shown to induce apoptosis, or programmed cell death, in tumor cells. This medicinal compound acts as an inhibitor of protein kinases, which play a crucial role in regulating the cell cycle and are often overactive in cancer cells. 3-Dodecenal has shown promising results in inhibiting cancer cell growth in Chinese hamster ovary cells and may have potential as a natural alternative to traditional cancer treatments. In addition, this compound has been detected in human urine and is believed to have potential health benefits beyond its anticancer properties.</p>
    Formula:C12H22O
    Purezza:Min. 95%
    Peso molecolare:182.3 g/mol

    Ref: 3D-TCA08357

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  • 1,5-Bis(4-amidinophenoxy)-2-pentanol

    CAS:
    <p>Please enquire for more information about 1,5-Bis(4-amidinophenoxy)-2-pentanol including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>
    Formula:C19H24N4O3
    Purezza:Min. 95%
    Peso molecolare:356.4 g/mol

    Ref: 3D-IFA99132

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  • (3R,4R,5S)-Ethyl 4-(N-(tert-butyl)acetamido)-5-(diallylamino)-3-(pentan-3-yloxy)cyclohex-1-enecarboxylate

    CAS:
    <p>(3R,4R,5S)-Ethyl 4-(N-(tert-butyl)acetamido)-5-(diallylamino)-3-(pentan-3-yloxy)cyclohex-1-enecarboxylate is a synthetic metabolite of the drug etravirine. It is an impurity in the drug product. The impurity is characterized as a white to off-white crystalline solid with a molecular weight of 531.6 g/mol and melting point of 170°C. It is soluble in methanol, ethanol, acetone and chloroform, but insoluble in water. (3R,4R,5S)-Ethyl 4-(N-(tert-butyl)acetamido)-5-(diallylamino)-3-(pentan-3-yloxy)cyclohex-1-enecarboxylate can be synthesized from commercially available starting materials</p>
    Formula:C26H44N2O4
    Purezza:Min. 95%
    Peso molecolare:448.6 g/mol

    Ref: 3D-BBB32407

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  • Emtricitabine impurity 17

    CAS:
    <p>Please enquire for more information about Emtricitabine impurity 17 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>
    Formula:C8H10FN3O4S
    Purezza:Min. 95%
    Peso molecolare:263.24 g/mol

    Ref: 3D-IE183412

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  • Amlodipine EP Impurity F maleate

    CAS:
    <p>Amlodipine EP Impurity F maleate is an impurity of amlodipine, a drug product. It is a natural substance that has been classified as an API impurity in the United States Pharmacopeia (USP). The chemical name for this drug is 3-(2-chlorophenyl)-1-methyl-5-(o-tolyloxy)-2,4-dihydro-6H-[1,3]thiazolo[3,2-a]pyrimidin-7-one. Amlodipine EP Impurity F maleate has the following properties: C12H9ClNO2S and a melting point of 210°C with a purity of 99.5%. This compound was synthesized by custom synthesis and is used as an analytical standard for HPLC. This compound was also used during the development of amlodipine to determine its metabolism studies.</p>
    Formula:C19H23ClN2O5•C4H4O4
    Purezza:Min. 95%
    Peso molecolare:510.92 g/mol

    Ref: 3D-IA182779

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  • Amiodarone impurity E

    CAS:
    <p>Amiodarone impurity E is a nucleophilic compound that is synthesized by the acylation of a diazonium salt with an amine. It has been shown to be active against staphylococci, but not against subtilis. The reaction may be catalyzed by acid or chloride. Amiodarone impurity E is also demethylated and dehydrated to form the final product, amiodarone.</p>
    Formula:C19H18O3
    Purezza:Min. 95%
    Colore e forma:Powder
    Peso molecolare:294.34 g/mol

    Ref: 3D-IA63609

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  • Sitagliptin monohydrochloride monohydrate

    CAS:
    <p>Sitagliptin monohydrochloride monohydrate is an inhibitor of dipeptidyl peptidase-4 (DPP-4), which is responsible for the degradation of incretin hormones. It is used in the treatment of type 2 diabetes mellitus, as it increases insulin secretion and reduces blood glucose levels. Recent studies have shown that Sitagliptin has anticancer properties, as it induces apoptosis in cancer cells. It also inhibits protein kinases, which are involved in tumor growth and metastasis. Capsaicin, a compound found in chili peppers, has been shown to enhance the anticancer activity of Sitagliptin in Chinese hamster ovary cells. The drug is excreted primarily through urine and has a low potential for drug interactions with other kinase inhibitors. Overall, Sitagliptin monohydrochloride monohydrate shows great promise as both a diabetes medication and an anticancer agent.</p>
    Formula:C16H18ClF6N5O2
    Purezza:Min. 95%
    Colore e forma:Powder
    Peso molecolare:461.79 g/mol

    Ref: 3D-MJB15692

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  • 2,2',4,4',6,6'-Hexachlorobiphenyl

    Prodotto controllato
    CAS:
    <p>2,2',4,4',6,6'-Hexachlorobiphenyl (PCB-136) is a potent anticancer agent that has been shown to induce apoptosis in cancer cells. It acts as a kinase inhibitor by blocking the activity of specific kinases involved in tumor growth and progression. PCB-136 has been studied extensively in human and Chinese hamster ovary cells and has been found to be highly effective against various types of cancer. This medicinal analog also exhibits inhibitory effects on the protein kinases that regulate cell division and proliferation, making it a promising candidate for cancer therapy. In addition, PCB-136 shows potential for use as a urinary biomarker for exposure to environmental pollutants due to its persistence in the environment and ability to accumulate in body tissues.</p>
    Formula:C12H4Cl6
    Purezza:Min. 95%
    Peso molecolare:360.9 g/mol

    Ref: 3D-IBA97903

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  • (-)-Sabinene

    CAS:
    <p>(-)-Sabinene is a natural compound found in urine and various medicinal plants, including Chinese herbs. It has been identified as an analog of another natural compound that exhibits potent anticancer activity. (-)-Sabinene has been shown to inhibit the activity of certain proteins involved in cell cycle regulation and apoptosis, which are important processes for the growth and survival of cancer cells. In addition, (-)-Sabinene has been found to have inhibitory effects on tumor kinase activity, making it a promising candidate for the development of new anticancer drugs. Studies have shown that (-)-Sabinene can effectively inhibit the growth of various types of cancer cells, making it a potential therapeutic agent for the treatment of cancer.</p>
    Formula:C10H16
    Purezza:Min. 95%
    Colore e forma:Clear Liquid
    Peso molecolare:136.23 g/mol

    Ref: 3D-KAA40816

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