APIs per la ricerca e le impurità
I principi attivi farmaceutici (API) sono le sostanze nei farmaci responsabili dei loro effetti terapeutici. In questa sezione troverai una vasta gamma di API destinati all'uso in ricerca. Questi composti sono essenziali per lo sviluppo, il test e la validazione di nuove formulazioni farmaceutiche. Presso CymitQuimica, offriamo API di alta qualità per supportare la ricerca nella scoperta e nello sviluppo di farmaci.
Sottocategorie di "APIs per la ricerca e le impurità"
- Aminoacidi e Derivati(12.439 prodotti)
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- Derivati delle Benzodiazepine(335 prodotti)
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- Esteri e Derivati(42.306 prodotti)
- Acidi Grassi e Derivati Lipidici(32.486 prodotti)
- Flavonoidi e Polifenoli(17.100 prodotti)
- Radicali Liberi e Agenti Ossidanti/Riducenti(214 prodotti)
- Chetoni e Derivati(2.693 prodotti)
- Antibiotici Naturali e Semisintetici(6.406 prodotti)
- Nitrili e Derivati Ciano(3.070 prodotti)
- Nitrosammine e Derivati(55 prodotti)
- Nucleosidi e Nucleotidi(3.491 prodotti)
- Fosfati e Fosfonati Organici(1.203 prodotti)
- Solfonati e Solfati Organici(10.450 prodotti)
- Composti Organometallici(4.425 prodotti)
- Altri(6.338 prodotti)
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- Polimeri e Derivati(100 prodotti)
- Derivati delle Purine e Pirimidine(8.972 prodotti)
- Derivati della Chinazolina e Chinolina(66.194 prodotti)
- Chinoni e Derivati(24.378 prodotti)
- Sali e Derivati degli API(92.808 prodotti)
- Steroidi e Derivati(4.986 prodotti)
- Sulfonamidi e Derivati(2.607 prodotti)
- Terpenoidi e Derivati(3.860 prodotti)
- Tiazolidinedioni e Tiopirani(2.755 prodotti)
- Composti β-Adrenergic(231 prodotti)
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Trovati 66898 prodotti di "APIs per la ricerca e le impurità"
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Cimetidine
CAS:Cimetidine is a histamine-2 receptor antagonist that inhibits gastric acid secretion and reduces the activity of stomach enzymes. It is used to treat peptic ulcers, gastroesophageal reflux disease, and Zollinger-Ellison syndrome. Cimetidine has been shown to inhibit the activity of drug-metabolizing enzymes such as cytochrome P450. Cimetidine also inhibits the transport protein P-glycoprotein (P-gp), which leads to increased concentrations of some drugs in the blood and tissues. This inhibition may lead to an increase in cardiac effects with certain drugs, such as x-ray diffraction data with taxol or h1 antagonists.
Formula:C10H16N6SPurezza:Min. 95%Colore e forma:White PowderPeso molecolare:252.34 g/molN4-Acetyl sulfadoxine
CAS:N4-Acetyl sulfadoxine is a drug that is used to treat urinary tract infections in women and children. It is also used to treat bacterial infections of the skin, lungs, and joints. N4-Acetyl sulfadoxine may be effective against prostatitis caused by E. coli or Mycoplasma pneumoniae by inhibiting the production of prostaglandins. This drug works by binding to dihydropteroate synthase, which prevents folic acid from being incorporated into the bacterial cell wall, thereby inhibiting bacterial growth.Formula:C14H16N4O5SPurezza:Min. 95%Colore e forma:PowderPeso molecolare:352.37 g/molN-((-3-(3-Fluoro-4-(4-morpholinyl)phenyl)-2-oxo-5-oxazolidinyl)methyl) acetamide
CAS:N-((-3-(3-Fluoro-4-(4-morpholinyl)phenyl)-2-oxo-5-oxazolidinyl)methyl) acetamide is a custom synthesis, drug product, niche, Metabolite, Drug Development, CAS No. 224323-50-6. It is a natural compound and has pharmacopoeia and API impurity. It is an analytical standard for HPLC and research and development. It is a high purity synthetic with impurity standard.Formula:C16H20FN3O4Purezza:Min. 95%Colore e forma:PowderPeso molecolare:337.35 g/molN,N'-Bis[2-[[[5-[(dimethylamino)methyl]-2-furanyl]methyl]thio]ethyl]-2-nitroethene-1,1-diamine
CAS:N,N'-Bis[2-[[[5-[(dimethylamino)methyl]-2-furanyl]methyl]thio]ethyl]-2-nitroethene-1,1-diamine is a drug development impurity that has been shown to be an API impurity in the synthesis of gatifloxacin. N,N'-Bis[2-[[[5-[(dimethylamino)methyl]-2-furanyl]methyl]thio]ethyl]-2-nitroethene-1,1-diamine is often used as a HPLC standard and in research and development. It may have some pharmacopoeia use as an analytical standard. The structural formula is: CAS No.: 72126-78-4 Molecular Formula: C14H18N3O6S Molecular Weight: 328.38 Purity (GC): 99.9Formula:C22H35N5O4S2Purezza:Min. 95%Colore e forma:Red PowderPeso molecolare:497.68 g/molAtorvastatin epoxy tetrahydrofuran impurity
CAS:Atorvastatin epoxy tetrahydrofuran impurity is a byproduct of the synthesis process. It is a white crystalline powder that is soluble in organic solvents and sparingly soluble in water. Atorvastatin epoxy tetrahydrofuran impurity has been shown to be an impurity of atorvastatin. It is not known to have any biological activity, but it may pose a health risk if present in large quantities.Formula:C26H24FNO5Purezza:Min. 95%Colore e forma:PowderPeso molecolare:449.47 g/mol4-Methoxy-N,N-dimethyl-phenethylamine
CAS:Prodotto controllato4-Methoxy-N,N-dimethylphenethylamine is a natural product that has been shown to inhibit the transfer of bacteria from the environment to food. It also has regulatory properties and can be used as a supplement in dietary drinks. 4-Methoxy-N,N-dimethylphenethylamine is an alkaloidal extract and has been shown to have antibacterial activity against Escherichia coli, Salmonella enterica, and Listeria monocytogenes. This compound was also found to have diffraction properties, which are related to its ability to bind DNA in bacterial cells.Formula:C11H17NOPurezza:Min. 95%Colore e forma:Clear LiquidPeso molecolare:179.26 g/molTenofovir disoproxil related compound B
CAS:Tenofovir disoproxil related compound B is a peptidyl prodrug that is metabolized by esterases to tenofovir. It has been shown to be an effective agent against Mycobacterium tuberculosis and other bacterial species. Tenofovir disoproxil related compound B was also found to inhibit protein synthesis in Mycobacterium avium and Mycobacterium smegmatis, but not in Escherichia coli. This drug binds to the ribosome's 30S subunit, which blocks the binding of aminoacyl-tRNA and prevents the formation of peptide bonds. The mechanism of action for this drug is similar to that of the antibiotic erythromycin.Formula:C8H9N5Purezza:Min. 98 Area-%Peso molecolare:175.19 g/molEsomeprazole sodium
CAS:Esomeprazole is a proton pump inhibitor used to treat gastroesophageal reflux disease and other conditions where there is too much stomach acid. It is available as a capsule or tablet in doses of 20, 40, and 60 mg. Esomeprazole inhibits the production of gastric acid by blocking the hydrogen/potassium adenosine triphosphate (H+/K+ ATPase) enzyme system at the secretory surface of the gastric parietal cells. Omeprazole is an acidic drug that blocks the H+/K+ ATPase enzyme system. The two drugs have been compared in two-way crossover studies using healthy volunteers who were given omeprazole magnesium for one week followed by esomeprazole sodium for another week. There was no difference in their effect on acid secretion or on heartburn relief. The plasma concentrations of both drugs increased with increasing dose, but there was no significant difference between them in terms of either
Formula:C17H18N3NaO3SPurezza:(%) Min. 95%Colore e forma:PowderPeso molecolare:367.4 g/mol1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3.5-pyridinecarboxylic acid dimethyl ester
CAS:1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3.5-pyridinecarboxylic acid dimethyl ester is a creatine kinase inhibitor that blocks the synthesis of creatine phosphate, which is an important energy source for muscle contraction. Creatine kinase inhibitors are used in the treatment of congestive heart failure and myocardial infarct. They also have vasodilatory effects on blood vessels and can be used to treat hypertension. The elimination rate of 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3.5-pyridinecarboxylic acid dimethyl ester depends on its formulation: solid dispersions have a half life of about 3 hours whereas orally administered doses have a half life of about 8 hours.Formula:C17H18N2O6Purezza:Min. 95%Colore e forma:Yellow PowderPeso molecolare:346.33 g/mol1,3-Bis[(p-chlorobenzylidene)amino]guanidine hydrochloride
CAS:1,3-Bis(p-chlorobenzylidene)amino]guanidine hydrochloride (1,3-BCBGAH) is a method for the determination of p-hydroxybenzoic acid in reaction solutions. It is used as an analytical reagent in the analysis of p-hydroxybenzoic acid in pharmaceuticals and other organic chemicals. The matrix effect can be reduced by adding quillaja saponaria to the extraction solution. The main application of this compound is for the detection of resistant mutants in infectious diseases such as liver lesions and tissue infection. 1,3-BCBGAH has also been shown to be effective against robenidine and polymyxin B., with a more favorable toxicity profile than maduramicin ammonium or anhydrous sodium.Formula:C15H14Cl3N5Purezza:Min. 95%Colore e forma:White PowderPeso molecolare:370.66 g/molCalcipotriol EP impurity E
Calcipotriol EP Impurity E is a synthetic impurity that is found in the calcipotriol EP API. Calcipotriol EP Impurity E is an impurity standard for HPLC and can be used in drug development, research and development, and pharmacopoeia. It has been shown to have no significant effect on the pharmacological activity of calcipotriol EP.
Formula:C27H42O3Purezza:Min. 95 Area-%Colore e forma:PowderPeso molecolare:414.62 g/molBiotin impurity C
CAS:Biotin impurity C is a metabolite that is found in drugs that contain biotin. It is an impurity standard for HPLC analysis, which can be used to identify and quantify the amount of biotin in a drug product. Biotin impurity C is also used as an analytical standard. This compound has been shown to have pharmacological properties, such as anti-inflammatory effects and immunomodulatory effects.Formula:C9H14N2O2SPurezza:Min. 95%Peso molecolare:214.28 g/mol2'-Deoxy-2',2'-difluorocytidine 5'-triphosphate sodium, 10 mM aqueous solution
CAS:2'-Deoxy-2',2'-difluorocytidine 5'-triphosphate sodium, 10 mM aqueous solution is an analytical standard that is used in metabolism studies and as an impurity in some pharmaceuticals. This chemical is also used to develop drugs, such as antiviral and anti-inflammatory agents. 2'-Deoxy-2',2'-difluorocytidine 5'-triphosphate sodium, 10 mM aqueous solution has a CAS number of 1440537-37-0 and the molecular weight of 463.88 g/mol. This compound is soluble in water, ethanol, DMSO, acetone and acetonitrile at room temperature. The purity for this compound is > 99%.
Formula:C9H14F2N3O13P3•NaxPurezza:Min. 95%Colore e forma:Clear LiquidPeso molecolare:503.14 g/mol(RS)-Isopropyl 2-methoxyethyl 1,4-dihydro-2,6-dimethyl-4-(4-nitrophenyl)pyridine-3,5-dicarboxylate
CAS:(RS)-Isopropyl 2-methoxyethyl 1,4-dihydro-2,6-dimethyl-4-(4-nitrophenyl)pyridine-3,5-dicarboxylate is a white to off-white crystalline powder that is soluble in methanol and slightly soluble in water. It can be used as an impurity standard for the API drug product, research and development and metabolism studies. The CAS number for this compound is 2200280-99-3. This compound has a purity of 99% or greater with an analytical purity of 99.9%. This compound has been shown to have a melting point of about 237°C and a density of 1.06 g/cm3. This compound is insoluble in ether and acetone.Formula:C21H26N2O7Purezza:Min. 95%Colore e forma:Light (Or Pale) Yellow To Yellow SolidPeso molecolare:418.44 g/molTyrosol glucuronide
CAS:Tyrosol is a phenolic compound found in olive oil and other plant sources. It has been shown to have antioxidant, anti-inflammatory, and anti-cancer activities. Tyrosol glucuronide is the main form of tyrosol found in urine samples. The absorption process of tyrosols is due to their uptake by the liver cells, where they are converted into fatty acids and then conjugated with glucuronic acid. Tyrosols are also metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. Studies have shown that tyrosols can help lower blood pressure and improve insulin resistance in women.Formula:C14H18O8Purezza:Min. 95%Colore e forma:PowderPeso molecolare:314.29 g/mol5-((tert-Butylamino)methyl)-3-(3-fluoro-(2-morpholinyl)phenyl)oxazolidin-2-one
5-((tert-Butylamino)methyl)-3-(3-fluoro-(2-morpholinyl)phenyl)oxazolidin-2-one (5FAMPO) is a metabolite of the drug product, CAS No. 109467-92-6, and has been synthesized for use as an analytical reference standard and impurity standard in drug development studies. 5FAMPO is a synthetic molecule that has not been found in nature, but is structurally similar to natural molecules. 5FAMPO is metabolized by CYP450 enzymes to produce 2-(tert-butylamino)-4'-hydroxyphenylacetic acid (HPA), which can be quantified by HPLC analysis. 5FAMPO is also used as a research and development compound and pharmacopoeia impurity standard.Formula:C18H26FN3O3Purezza:Min. 95%Peso molecolare:351.42 g/molFluticasone propionate EP Impurity F
CAS:Fluticasone Propionate EP Impurity F is an impurity of Fluticasone Propionate. Fluticasone Propionate is a synthetic glucocorticoid used in the treatment of asthma and other allergic disorders. Impurity F is a metabolite of Fluticasone Propionate and has been detected in human plasma at low levels (5% of total fluticasone propionate). The metabolism of Fluticasone Propionate to Impurity F has been studied in rat, mouse, dog and man. br>br> The following table summarizes the metabolic pathways that have been identified for this impurity: br>br> Metabolism studies indicate that Impurity F is mainly metabolized by CYP3A4 to form conjugates with glucuronic acid or sulfates. It may also be hydrolyzed to form 5α-flurostan-3β,17β-dFormula:C25H29F3O5SPurezza:Min. 95%Colore e forma:PowderPeso molecolare:498.56 g/mol3-[[[2-[(Aminoiminomethyl)amino]-4-thiazolyl]methyl]thio]-propanoic acid methyl ester
CAS:3-[[[2-[(Aminoiminomethyl)amino]-4-thiazolyl]methyl]thio]-propanoic acid methyl ester is an impurity standard for HPLC. The compound is a metabolite of the drug product and is naturally occurring. The CAS number for 3-[[[2-[(Aminoiminomethyl)amino]-4-thiazolyl]methyl]thio]-propanoic acid methyl ester is 76824-14-1. It has a purity of > 99% and can be used in research and development, analytical applications, or as an impurity standard for HPLC.
Formula:C9H14N4O2S2Purezza:Min. 95%Peso molecolare:274.37 g/mol
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