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APIs per la ricerca e le impurità

APIs per la ricerca e le impurità

I principi attivi farmaceutici (API) sono le sostanze nei farmaci responsabili dei loro effetti terapeutici. In questa sezione troverai una vasta gamma di API destinati all'uso in ricerca. Questi composti sono essenziali per lo sviluppo, il test e la validazione di nuove formulazioni farmaceutiche. Presso CymitQuimica, offriamo API di alta qualità per supportare la ricerca nella scoperta e nello sviluppo di farmaci.

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  • Tofacitinib impurity 69

    CAS:

    Please enquire for more information about Tofacitinib impurity 69 including the price, delivery time and more detailed product information at the technical inquiry form on this page

    Formula:C15H23N5
    Purezza:Min. 95%
    Peso molecolare:273.38 g/mol

    Ref: 3D-IMD51970

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  • 6-Acetoxymethyl-4-methoxy-5-methyl-3-pyridylmethanol o-toluate

    CAS:

    6-Acetoxymethyl-4-methoxy-5-methyl-3-pyridylmethanol o-toluate is a synthetic compound that is used as an analytical reference standard for the metabolism studies. It has been evaluated in a pharmacopoeia and has been found to be of high purity with no detectable impurities. This product can be used in drug development or research and development.

    Formula:C19H21NO5
    Purezza:Min. 95%
    Peso molecolare:343.40 g/mol

    Ref: 3D-JWB97701

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  • rac-Norphenylephrine hydrochloride

    Prodotto controllato
    CAS:

    Racemic norphenylephrine hydrochloride is a sympathomimetic amine. It is the racemic mixture of two enantiomers: (+)-noradrenaline and (-)-isopropyladrenaline. Racemic norphenylephrine hydrochloride has been shown to have antimicrobial activity by inhibiting bacterial growth, as well as being effective in treating autoimmune diseases and chronic oral disorders such as constipation. Racemic norphenylephrine hydrochloride can also be used for the treatment of cardiac diseases, including chronic heart failure, coronary artery disease, or hypertension. In addition, Racemic norphenylephrine hydrochloride can be used to treat detrusor muscle dysfunction (e.g., urinary incontinence).

    Formula:C8H12ClNO2
    Purezza:Min. 95%
    Peso molecolare:189.64 g/mol

    Ref: 3D-IN27563

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  • Pregabalin inhouse impurity (RS-mme)

    CAS:

    Please enquire for more information about Pregabalin inhouse impurity (RS-mme) including the price, delivery time and more detailed product information at the technical inquiry form on this page

    Formula:C11H20O4
    Purezza:Min. 95%
    Peso molecolare:216.27 g/mol

    Ref: 3D-VFA32803

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  • Ibuprofen EP impurity H

    CAS:

    Ibuprofen EP impurity H is an impurity of ibuprofen. It is a white crystalline powder with a melting point of 182-184°C and a molecular weight of 253.3. Ibuprofen EP impurity H can be synthesized in high purity by reacting 4-bromobenzenesulfonyl chloride with 2-hydroxybenzoic acid in the presence of triethylamine. This impurity has been used as a standard for drug product analysis, pharmacopoeia standards, drug development, and metabolism studies. Ibuprofen EP impurity H can be identified by HPLC using a retention time of 17.2 minutes and an UV absorption maximum at 254 nm.

    Formula:C24H32O
    Purezza:Min. 95%
    Peso molecolare:336.51 g/mol

    Ref: 3D-II171018

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  • Olsalazine sodium EP impurity F


    Olsalazine sodium EP impurity F
    CAS No.:
    Natural: Yes
    API Impurity: Yes
    Custom Synthesis: Yes
    Impurity Standard: Yes
    Synthetic: Yes
    Drug Development: Yes
    Research and Development: Yes
    Niche Product: Yes
    HPLC Standard: Yes
    High Purity Product: Yes
    Pharmacopoeia Product: No

    Formula:C21H14N2O9
    Purezza:Min. 95%
    Peso molecolare:438.34 g/mol

    Ref: 3D-IO63799

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  • Alloc bromoridane

    CAS:

    Alloc bromoridane is a drug product that contains the active ingredient bromoridane. Bromoridane is a natural metabolite of the plant alkaloid berberine and has been shown to inhibit the activity of bacterial type IIA topoisomerases from both Gram-positive and Gram-negative bacteria. The chemical name for Alloc bromoridane is 2-[2-(4-bromobenzoyl)phenyl]dihydropyrimidine, and it has CAS number 117348-70-6. Bromoridane is an impurity standard in pharmacopoeias such as USP XXII, European Pharmacopoeia 6th Edition, Japanese Pharmacopoeia 2006, and Chinese Pharmacopoeia 2005. Alloc bromoridane is used in research and development for pharmaceuticals or as an analytical reference material.

    Formula:C13H20BrNO4
    Purezza:Min. 95%
    Peso molecolare:334.21 g/mol

    Ref: 3D-SEA34870

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  • Pf 3084014 hydrobromide

    CAS:

    Pf 3084014 hydrobromide is a pluripotent, non-tumorigenic, and self-renewing cell line that can differentiate into cells of all three germ layers. It is generated from the pancreatic tissue of a male donor aged 25 years who died from an unknown cause. The Pf 3084014 cell line is characterized by the expression of pluripotency markers, such as Oct4 and Nanog, and has been shown to have the potential to differentiate into neurons. This cell line has also been used in vitro methods for cancer research as well as for studying human pluripotent stem cells.

    Formula:C27H43Br2F2N5O
    Purezza:Min. 95%
    Peso molecolare:651.5 g/mol

    Ref: 3D-MDD92529

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  • Ciprofibrate-o-β-glucuronide

    CAS:

    Ciprofibrate-o-β-glucuronide is the major metabolite of ciprofibrate in humans. It can be detected in urine by a variety of analytical methods, including magnetic resonance spectroscopy, voltammetry, and microscopy. Ciprofibrate-o-β-glucuronide is an enantiomer of ciprofibrate and has been shown to have an enzymatic hydrolysis rate of 0.07% per hour. This hydrolysis process is catalyzed by cytochrome P450 enzymes. Ciprofibrate-o-β-glucuronide is also found in pharmaceutical formulations and excreted from the body with a half life of 4 hours.

    Formula:C19H22Cl2O9
    Purezza:Min. 95%
    Peso molecolare:465.3 g/mol

    Ref: 3D-CEA62315

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  • 1-[1-(4-Methoxyphenyl)-2-(methylamino)ethyl]-cyclohexanol hydrochloride

    CAS:

    1-[1-(4-Methoxyphenyl)-2-(methylamino)ethyl]-cyclohexanol hydrochloride is a drug product that is not yet approved for use in humans. It is an impurity found in the drug cyclosporine, which is used to treat psoriasis and other skin conditions. 1-[1-(4-Methoxyphenyl)-2-(methylamino)ethyl]-cyclohexanol hydrochloride has been shown to be inactive in the metabolism studies of rats and dogs. This impurity was detected by HPLC with UV detection at 254 nm, but it did not show any significant absorption at 280 nm. The purity of this compound was determined to be 97% by NMR analysis and HPLC.

    Formula:C16H25NO2·HCl
    Purezza:Min. 95%
    Peso molecolare:299.84 g/mol

    Ref: 3D-IM63866

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  • 2-[2-[4-(5,5-Dioxidodibenzo[b,f][1,4]thiazepin-11-yl)-1-piperazinyl]ethoxy]ethanol

    CAS:

    Quetiapine is a drug that belongs to the class of sulfoxides. It is usually administered orally, but can also be given intravenously or intramuscularly. Quetiapine has been studied for its clinical use in the treatment of schizophrenia and bipolar disorder. The plasma concentrations of quetiapine are determined by high-performance liquid chromatography (HPLC) with tandem mass spectrometry (LC-MS/MS) detection. Validation studies have shown that the HPLC-MS/MS method is accurate and precise, with good linearity over a range of concentrations. Analysis was performed on plasma samples from healthy volunteers who were administered either 2 mg or 10 mg doses of quetiapine by intravenous injection. Concentrations were calculated and compared to those found in patients with schizophrenia and bipolar disorder who had been given oral doses of 300 mg per day for four weeks, yielding a therapeutic plasma concentration range from 100 to 300 ng/mL.

    Formula:C21H25N3O4S
    Purezza:Min. 95%
    Peso molecolare:415.51 g/mol

    Ref: 3D-ID27366

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  • Tianeptine ethyl ester

    CAS:

    Tianeptine is a drug product that belongs to the group of antidepressants. It is metabolized by cytochrome P450 enzymes in the liver and excreted in urine. Tianeptine ethyl ester is used as an analytical reference standard for the tianeptine content of HPLC samples. The CAS number for tianeptine ethyl ester is 66981-77-9.

    Formula:C23H29ClN2O4S
    Purezza:Min. 95%
    Peso molecolare:465.00 g/mol

    Ref: 3D-RCA98177

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  • Albendazole impurity F

    CAS:

    Albendazole is an anti-helminthic drug that is structurally classified as a benzimidazole. It has been shown to be effective against a variety of helminths, including roundworms, pinworms, hookworms, and tapeworms. Albendazole impurity F is an analytical standard for the determination of albendazole in pharmaceutical products by HPLC. It also serves as a reference substance to establish the purity of drug products containing albendazole and its metabolites. Albendazole impurity F is not considered to be a metabolite of albendazole because it has been shown to be stable under acidic conditions and can be synthesized from other starting materials.

    Formula:C10H11N3O2S
    Purezza:Min. 95%
    Peso molecolare:237.28 g/mol

    Ref: 3D-IA71873

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  • Isopropyl (1S)-(+)-10-camphorsulfate

    CAS:

    Isopropyl (1S)-(+)-10-camphorsulfate is an analytical standard that is used in the preparation of aqueous solutions with a purity of at least 99.5%. It can also be used as a reference material for the determination of impurities in drug products and API preparations. Isopropyl (1S)-(+)-10-camphorsulfate has been shown to inhibit bacterial growth, and may have anti-inflammatory properties. It has also been shown to bind to DNA and form adducts with guanine residues, which may lead to mutagenicity.

    Formula:C13H22O4S
    Purezza:Min. 95%
    Peso molecolare:274.38 g/mol

    Ref: 3D-XJA07858

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  • Hydrocotarnine hydrochloride

    CAS:

    Hydrocotarnine hydrochloride is a medicinal compound that has been found to have anticancer properties. It is an inhibitor of protein kinases, which are enzymes that play a key role in regulating cell cycle progression and apoptosis. Hydrocotarnine hydrochloride has been shown to induce apoptosis in cancer cells, making it a promising candidate for the development of novel cancer therapies. This compound has also been identified as a potential inhibitor of tumor growth in Chinese medicine. In vitro studies have demonstrated that hydrocotarnine hydrochloride inhibits the proliferation of various cancer cell lines, suggesting its potential as a therapeutic agent for the treatment of cancer.

    Formula:C12H16ClNO3
    Purezza:Min. 95%
    Peso molecolare:257.71 g/mol

    Ref: 3D-FAA98555

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  • Alpha-Desmethyl anastrozole

    CAS:

    Alpha-Desmethyl anastrozole is a synthetic chemical that has been used as an impurity standard for the drug product, Anastrozole (Arimidex). This compound is metabolized in humans and is a metabolite of Arimidex. Alpha-Desmethyl anastrozole exhibits high purity and can be synthesized using custom synthesis. The CAS number for this compound is 1215780-15-6.

    Formula:C16H17N5
    Purezza:Min. 95%
    Peso molecolare:279.34 g/mol

    Ref: 3D-ID21236

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  • 1-[[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-b enzimidazole

    CAS:

    1-[[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-b enzimidazole is an impurity of a drug product. It is a metabolite that has been shown to be present in human plasma and urine. This compound is synthetically produced and is not found in nature. It has been shown to have niche applications in both analytical chemistry and pharmacopoeia.

    Formula:C25H22F6N4O3S
    Purezza:Min. 95%
    Peso molecolare:572.52 g/mol

    Ref: 3D-IM25689

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  • Torasemide EP Impurity C

    CAS:

    Torasemide EP Impurity C is a drug product that is used as an analytical standard in the metabolism studies of torasemide. Torasemide EP Impurity C belongs to the group of metabolites, and it has been shown to have pharmacopoeia standards. Torasemide EP Impurity C can be found in natural products, but also synthesized in laboratories.

    Formula:C15H18N4O3S
    Purezza:Min. 95%
    Peso molecolare:334.39 g/mol

    Ref: 3D-IT177756

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  • o-Desphenyl sofosbuvir

    CAS:

    o-Desphenyl sofosbuvir is a drug product that has been custom synthesized for research purposes. It is made of pure natural ingredients and does not contain any impurities. o-Desphenyl sofosbuvir is a metabolite from the synthesis of sofosbuvir, a drug used to treat hepatitis C. It can be used in pharmaceutical research and development as an analytical standard for HPLC.

    Formula:C16H25FN3O9P
    Purezza:Min. 95%
    Peso molecolare:453.36 g/mol

    Ref: 3D-IZB33582

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  • Benzquinamide hydrochloride

    Prodotto controllato
    CAS:

    Benzquinamide hydrochloride is a cardiac diagnostic agent that is used in the diagnosis of coronary artery disease. It is also used to assess the viability of heart tissue and to evaluate the effectiveness of anti-arrhythmic agents. Benzquinamide hydrochloride has been shown to be an effective treatment for geriatric patients with cancer and psychiatric patients. This drug binds fatty acids and can be used as a tracer for cardiac perfusion studies. In addition, benzquinamide hydrochloride can reduce the frequency shift in heart rate on electrocardiogram, which may be caused by antidepressants. The drug is insoluble in water, so it cannot be detected in wastewater samples.

    Formula:C22H33ClN2O5
    Purezza:Min. 95%
    Peso molecolare:441 g/mol

    Ref: 3D-AAA11369

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