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APIs per la ricerca e le impurità

APIs per la ricerca e le impurità

I principi attivi farmaceutici (API) sono le sostanze nei farmaci responsabili dei loro effetti terapeutici. In questa sezione troverai una vasta gamma di API destinati all'uso in ricerca. Questi composti sono essenziali per lo sviluppo, il test e la validazione di nuove formulazioni farmaceutiche. Presso CymitQuimica, offriamo API di alta qualità per supportare la ricerca nella scoperta e nello sviluppo di farmaci.

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  • Deschloro amlodipine

    CAS:

    Deschloro amlodipine is a drug that is used for the treatment of high blood pressure. It belongs to a group of drugs called calcium channel blockers. Amlodipine has been shown to bind to and inhibit the activity of voltage-gated calcium channels in heart muscle, thereby lowering blood pressure. Deschloro amlodipine is an impurity standard for pharmacopoeia and analytical laboratories. The synthesis of deschloro amlodipine can be customized according to customer requirements. This product will be shipped as soon as possible after purchase.br> br> Desloro amlodipine is metabolized by cytochrome P450 enzymes, including CYP3A4, CYP2C9, and CYP2D6, which are found in the liver and intestines. These enzymes convert desloro amlodipine into two metabolites: 4-hydroxyamlodipine and 4

    Formula:C20H26N2O5
    Purezza:Min. 95%
    Peso molecolare:374.43 g/mol

    Ref: 3D-NDA15052

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  • Pravastatin diol lactone

    CAS:

    Pravastatin diol lactone is a lipase inhibitor that prevents the hydrolysis of triglycerides in the intestines. It also inhibits the synthesis of cholesterol by inhibiting hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase. Pravastatin diol lactone has been shown to be effective in reducing serum cholesterol levels in animal models and inhibiting esterification of cholesterol by preventing the conversion of HMG-CoA to mevalonic acid, which is an important step in the synthesis of cholesterol. Pravastatin diol lactone is a polyketide that was discovered from a fungus and chemically altered to produce this drug.

    Formula:C18H26O5
    Purezza:Min. 95%
    Peso molecolare:322.4 g/mol

    Ref: 3D-JGA34593

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  • Ornidazole-hydroxy

    CAS:

    Ornidazole-hydroxy is a drug product that is manufactured using HPLC. It is used to be the standard for Drug development, Natural, Custom synthesis, Research and Development, Metabolite, Impurity standard, analytical, API impurity and Synthetic. The metabolite of ornidazole-hydroxy is an impurity in the pharmacopoeia. Ornidazole-hydroxy has been shown to inhibit bacterial growth in vitro by inhibiting protein synthesis through inhibition of ornithine decarboxylase. Ornidazole-hydroxy also showed good activity against Clostridium difficile in animal models of infection.

    Formula:C7H10ClN3O4
    Purezza:Min. 95%
    Peso molecolare:235.62 g/mol

    Ref: 3D-MCA58079

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  • Ethyl 2-(6-amino-2,3-dichlorobenzyl)glycine

    CAS:

    Ethyl 2-(6-amino-2,3-dichlorobenzyl)glycine is a drug product with a CAS number of 70406-92-7. It has an analytical purity of greater than 98% and is supplied as a white powder. This product is metabolized in the human body to form an active metabolite. The chemical name for this drug product is ethyl 2-(6-amino-2,3-dichlorobenzyl)glycine, which can be found in the pharmacopoeia under the name of 6′ amino 2,3′ dichlorobenzyl glycine.

    Formula:C11H14Cl2N2O2
    Purezza:Min. 95%
    Peso molecolare:277.15 g/mol

    Ref: 3D-IE22945

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  • Duloxetine phenyl carbamate

    CAS:

    Duloxetine is a drug product that belongs to the class of drugs known as selective serotonin and norepinephrine reuptake inhibitors. Duloxetine is a metabolite of duloxetine phenyl carbamate, which is an impurity standard for HPLC analysis. Duloxetine has been shown to inhibit the metabolism of serotonin and norepinephrine in the brain, leading to increased amounts of these neurotransmitters. This medication has been studied in niche populations such as those with depression and diabetic neuropathy. Duloxetine also has high purity standards, meeting the requirements of pharmacopoeia.

    Formula:C25H23NO3S
    Purezza:Min. 95%
    Peso molecolare:417.50 g/mol

    Ref: 3D-XMB68609

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  • 5-Oxo Rosuvastatin

    CAS:

    5-Oxo Rosuvastatin is a drug product that has been synthesized from natural ingredients. It is an analytical standard for the impurity, 5-oxo-rosuvastatin, which is a potential impurity in the API, rosuvastatin. This drug product has been custom synthesized in order to provide an Impurity Standard for HPLC. This drug product is also used as a Synthetic Reference Standard for Drug Development and Research and Development.

    Formula:C22H26FN3O6S
    Purezza:Min. 95%
    Colore e forma:Off-White To Light (Or Pale) Yellow To Dark Yellow Solid
    Peso molecolare:479.52 g/mol

    Ref: 3D-FF103553

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  • Risperidone E-oxime impurity

    CAS:

    Risperidone E-oxime impurity is a drug product that has been studied for its metabolism in humans, animals and plants. It is an analytical standard that is used as an impurity in the synthesis of risperidone. Risperidone E-oxime impurity is also a synthetic compound with CAS No. 691007-09-7. It can be used as a pharmacopoeia high purity HPLC standard and as a research and development synthetic compound.

    Formula:C23H28F2N4O2
    Purezza:Min. 95%
    Colore e forma:Powder
    Peso molecolare:430.49 g/mol

    Ref: 3D-IR27738

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  • rac Enterodiol-d6

    CAS:

    Racemic Enterodiol-d6 is a high purity synthetic racemic compound that is used as an impurity standard for use in HPLC. The CAS number for Racemic Enterodiol-d6 is 104411-12-3. Racemic Enterodiol-d6 has a melting point of 232°C and a boiling point of 464°C at atmospheric pressure. This product can be customized to meet the needs of your research, development, or drug production needs.

    Formula:C18H22O4
    Purezza:Min. 95%
    Peso molecolare:308.4 g/mol

    Ref: 3D-EEA41112

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  • Doxylamine N-oxide

    CAS:

    Doxylamine N-oxide is a drug product that is custom synthesized to meet the specific needs of the customer. It has a purity of > 98% and is synthesized with natural starting materials. Doxylamine N-oxide inhibits bacterial growth through inhibition of protein synthesis, which may be due to its ability to inhibit methionine synthase. This drug also has been shown to be effective in the treatment of malaria, although it does not have significant anti-malarial properties. Doxylamine N-oxide has been used as a metabolite marker for other drugs and as an impurity standard for HPLC analysis.

    Formula:C17H22N2O2
    Purezza:Min. 95%
    Peso molecolare:286.37 g/mol

    Ref: 3D-ZDA43077

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  • N-Formyl leurosine

    CAS:

    N-Formyl leurosine is an inhibitor of fatty acid synthesis. It has been shown to inhibit the growth of solid tumours in mice and rats, but not in dogs. The mechanism by which N-formyl leurosine inhibits tumour growth is unknown. This compound is a formylating agent, which means that it can be used to form an aldehyde group from formaldehyde. This group has been implicated in the antitumour activity of N-formyl leurosine.

    Formula:C46H54N4O10
    Purezza:Min. 95%
    Peso molecolare:822.94 g/mol

    Ref: 3D-IF23552

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  • cis-Tadalafil

    CAS:

    Cis-Tadalafil is a potent inhibitor of phosphodiesterase 5, which is used to treat erectile dysfunction (ED) and primary pulmonary hypertension (PPH). It works by increasing blood flow to the penis, allowing men with ED to achieve and maintain an erection. Cis-Tadalafil is also used to treat symptoms of prostatic hyperplasia (enlarged prostate) in men. This drug has been shown to be effective in treating PPH by reducing pulmonary arterial pressure and improving exercise capacity. Cis-Tadalafil belongs to the carboline class of drugs and is a phosphodiesterase 5 inhibitor that selectively inhibits cGMP-specific phosphodiesterase type 5 (PDE5). This drug has been shown to be highly effective in treating both ED and PPH with minimal side effects.

    Formula:C22H19N3O4
    Purezza:Min. 95%
    Colore e forma:White/Off-White Solid
    Peso molecolare:389.4 g/mol

    Ref: 3D-FT27987

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  • Pramipexole EP Impurity C

    CAS:

    Pramipexole EP Impurity C is a synthetic impurity that is used as an impurity standard in the manufacture of Pramipexole EP. It is also used as a research and development tool for drug product, custom synthesis, CAS No. 1973461-14-1, and analytical studies. This compound has been shown to be a metabolite of Pramipexole EP and may have pharmacological properties. Pramipexole EP Impurity C has been found to inhibit the growth of certain bacteria, such as methicillin-resistant Staphylococcus aureus (MRSA) isolates.

    Formula:C20H32N6S2
    Purezza:Min. 95%

    Ref: 3D-FP165425

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  • Piperacilloic acid

    CAS:

    Piperacilloic acid is a synthetic compound that exhibits antibacterial activity. It has been shown to be effective against human pathogens, including urothelial carcinoma and human serum. Piperacilloic acid binds to the amino acids lysine and arginine in bacterial proteins and inhibits protein synthesis by inhibiting the function of enzymes that require these amino acids for their activity. The potency of piperacillin is low, but it is activated by hydrolysis in the acidic environment of the stomach or intestinal tract. Piperacilloic acid also has potential as a contraceptive agent because it may inhibit transcriptional regulation of genes that are involved in sperm production.

    Formula:C23H29N5O8S
    Purezza:(Elemental Analysis) Min. 90 Area-%
    Colore e forma:Powder
    Peso molecolare:535.57 g/mol

    Ref: 3D-FP27061

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  • Simvastatin acid

    CAS:

    Simvastatin acid is the active form of simvastatin, a drug used to lower blood cholesterol levels. Simvastatin acid inhibits HMG-CoA reductase, the enzyme that converts HMG-CoA to mevalonate. This conversion is a rate-limiting step in the synthesis of cholesterol and other lipids. Simvastatin acid binds to polymerase chain and drug transporter proteins, which leads to cell lysis. The concentration–time curve for simvastatin acid is linear and the half-life is approximately 12 hours. When simvastatin acid is administered with drugs that are potent inducers of CYP3A4 or UGT1A1 enzymes, there may be an increased risk for drug interactions. Simvastatin acid has shown no significant human pharmacokinetic interactions with food or grapefruit juice at doses up to 200 mg/day. There are limited data on the pharmacokinetics of simvastatin

    Formula:C25H40O6
    Purezza:Min. 95%
    Colore e forma:White Powder
    Peso molecolare:436.58 g/mol

    Ref: 3D-IS63828

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  • Roflumilast Impurity A

    CAS:

    Roflumilast impurity A is a metabolite of roflumilast. It is a drug product that is used as an analytical standard for the determination of roflumilast in HPLC analysis. Roflumilast impurity A is not natural and is synthetic. It has been shown to be a substrate for CYP1A2, CYP2C8, CYP2C9, and CYP3A4 enzymes. Studies have shown that it may be involved in the metabolism of roflumilast through hydroxylation and deamination.

    Formula:C16H14Cl2N2O3
    Purezza:Min. 95%
    Peso molecolare:353.2 g/mol

    Ref: 3D-IR168438

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  • Dicyclopropylamine hydrochloride

    CAS:

    Dicyclopropylamine hydrochloride is a tyrosine kinase inhibitor that blocks the activity of jak2. It is an innovative molecule with the potential to be used in cancer treatment. Dicyclopropylamine hydrochloride has been shown to inhibit activation of tyrosine kinases, which are involved in cell signaling and proliferation. Dicyclopropylamine hydrochloride also has anti-inflammatory properties, which may be due to its ability to inhibit prostaglandin synthesis. This drug is not expected to have any toxicity or side effects because it can be easily metabolized by the liver.br>br> Dicyclopropylamine hydrochloride is a white solid with a melting point of 175°C. It has no detectable odor, and it is soluble in water and ethanol. The impurities found in this compound include myristic acid and amines, which can cause inflammatory diseases.br>br> D

    Formula:C6H11N•HCl
    Purezza:Min. 95%
    Colore e forma:Powder
    Peso molecolare:133.62 g/mol

    Ref: 3D-FD141573

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  • Terbinafine dihydrochloride

    CAS:

    Terbinafine is a drug used in the treatment of onychomycosis, tinea versicolor and dandruff. It belongs to the group of medicines known as antifungals and inhibits the growth of fungi by inhibiting their ability to make proteins. Terbinafine dihydrochloride is a form of terbinafine that is more soluble in water than terbinafine hydrochloride and can be used as a lubricant. Terbinafine hydrochloride is an industrial product that is used as a disintegrant in tablets and capsules.

    Formula:C36H40N2
    Purezza:Min. 95%
    Peso molecolare:500.7 g/mol

    Ref: 3D-JMB36523

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  • N-Hydroxymethyl Sumatriptan

    CAS:

    N-Hydroxymethyl Sumatriptan is an analytical standard and a research and development impurity. It is also used as an API impurity in drug product manufacturing. N-Hydroxymethyl Sumatriptan can be synthesized by reacting the parent drug with hydroxyl radicals, which is a process that yields no side products. N-Hydroxymethyl Sumatriptan can be found in the following pharmacopoeia: United States Pharmacopoeia (USP) 11>, European Pharmacopoeia (EP), Japanese Pharmacopoeia (JP)13>, British Pharmacopoeia (BP), and Chinese Pharmacopiae (CPC).

    Formula:C15H23N3O3S
    Purezza:Min. 95%
    Peso molecolare:325.43 g/mol

    Ref: 3D-FH175834

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  • N-Nitroso dorzolamide


    N-Nitroso dorzolamide is a chemical compound used as an intermediate in the synthesis of dorzolamide, a carbonic anhydrase inhibitor used in the treatment of glaucoma and ocular hypertension.

    Formula:C10H15N3O5S3
    Purezza:Min. 95%
    Colore e forma:Powder
    Peso molecolare:353.44 g/mol

    Ref: 3D-IN182764

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  • Acarbose Impurity E

    CAS:

    Acarbose Impurity E is an impurity found in acarbose. It is a natural, API impurity and is a synthetic impurity standard. Acarbose Impurity E has been used in drug development research and development, as well as in the HPLC analysis of acarbose to generate a pharmacopoeia-grade purity standard.

    Purezza:Min. 95%

    Ref: 3D-FA175652

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