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APIs per la ricerca e le impurità

APIs per la ricerca e le impurità

I principi attivi farmaceutici (API) sono le sostanze nei farmaci responsabili dei loro effetti terapeutici. In questa sezione troverai una vasta gamma di API destinati all'uso in ricerca. Questi composti sono essenziali per lo sviluppo, il test e la validazione di nuove formulazioni farmaceutiche. Presso CymitQuimica, offriamo API di alta qualità per supportare la ricerca nella scoperta e nello sviluppo di farmaci.

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  • 4-(Phthalazin-1-yloxy)aniline

    CAS:

    4-(Phthalazin-1-yloxy)aniline is an analog of cyclin-dependent kinase (CDK) inhibitors that has shown promising anticancer activity. It inhibits the activity of CDKs, which are enzymes involved in regulating cell division and proliferation. This compound has been tested on Chinese hamster ovary cells and has demonstrated potent antiproliferative activity against various cancer cell lines. 4-(Phthalazin-1-yloxy)aniline induces apoptosis in tumor cells, leading to their death. This compound may be a potential candidate for the development of novel anticancer drugs that target CDKs and promote tumor cell death. Additionally, this compound can be detected in urine samples, making it a useful biomarker for cancer diagnosis and monitoring.

    Formula:C14H11N3O
    Purezza:Min. 95%
    Peso molecolare:237.26 g/mol

    Ref: 3D-ZFA36540

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  • (S,S)-IsoValganciclovir hydrochloride

    CAS:

    (S,S)-IsoValganciclovir hydrochloride is a drug product with a purity of 99.5% or greater that is used as a reference standard in drug development and analytical chemistry. It is metabolized to (2R,3R)-2-Amino-3-hydroxypropanoic acid by the enzyme valganciclovir hydrolase. The chemical name for (S,S)-IsoValganciclovir hydrochloride is 2-(Aminomethyl)valganciclovir. The CAS registry number for this compound is 1401562-13-7.

    Formula:C14H23ClN6O5
    Purezza:Min. 95%
    Peso molecolare:390.82 g/mol

    Ref: 3D-IV180935

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  • L-Valine 2-hydroxyethyl ester tosylate

    CAS:

    L-Valine 2-hydroxyethyl ester tosylate (L-V2HT) is a drug product that is synthesized by custom synthesis. It has high purity, analytical, and natural properties. L-V2HT is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. The active form of L-V2HT is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. L-V2HT also specifically binds to markers expressed at high levels in Mycobacterium tuberculosis strains (e.g., ESX-1 secretion system protein) and inhibits cell

    Formula:C14H23NO6S
    Purezza:Min. 95%
    Peso molecolare:333.4 g/mol

    Ref: 3D-IV178763

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  • 11-Oxo-betamethasone-17-carboxylic acid

    Prodotto controllato
    CAS:

    Please enquire for more information about 11-Oxo-betamethasone-17-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

    Formula:C21H25FO5
    Purezza:Min. 95%
    Peso molecolare:376.4 g/mol

    Ref: 3D-EDA57810

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  • Moexipril methyl ester analog hydrochloride

    CAS:
    Moexipril methyl ester analog hydrochloride is a drug product that has been custom synthesized for research and development. It is a high purity, analytical grade compound with CAS No. 1356841-17-2. Moexipril methyl ester analog hydrochloride is metabolized through metabolic studies and is a natural metabolite of the drug moexipril. This substance can be found in the pharmacopoeia and is used as an impurity standard. Moexipril methyl ester analog hydrochloride also has niche applications in synthetic chemistry research and development.
    Formula:C26H32N2O7•HCl
    Purezza:Min. 95%
    Colore e forma:Powder
    Peso molecolare:521 g/mol

    Ref: 3D-GEC84117

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  • N-Methyl formoterol fumarate

    CAS:

    N-Methyl formoterol fumarate is a drug product for the treatment of asthma and chronic obstructive pulmonary disease. It is a synthetic drug that has been approved by the FDA, but is also a metabolite of terbutaline. Metabolism studies have shown that N-methyl formoterol fumarate is an impurity in Terbutaline sulfate and Terbutaline hydrochloride. This drug is not active against bacteria, but may be used as an analytical standard to measure the purity of other drugs.

    Formula:C44H56N4O12
    Purezza:Min. 95%
    Peso molecolare:832.94 g/mol

    Ref: 3D-VWC13397

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  • (2S,2R,Trans)-saxagliptin

    CAS:

    (2S,2R,Trans)-saxagliptin is an anti-diabetic drug that belongs to the thiazolidinedione class of drugs. It is a synthetic compound that is metabolized by cytochrome P450 enzymes and excreted in urine. (2S,2R,Trans)-saxagliptin has been shown to inhibit the synthesis of glucose in liver cells and to lower blood glucose levels in diabetic animals. In addition, it has been shown to have anti-inflammatory effects by inhibiting the production of TNF-α and IL-6 cytokines.

    Formula:C18H25N3O2
    Purezza:Min. 95%
    Peso molecolare:315.40 g/mol

    Ref: 3D-PMC26598

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  • rac-Norphenylephrine hydrochloride

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    CAS:

    Racemic norphenylephrine hydrochloride is a sympathomimetic amine. It is the racemic mixture of two enantiomers: (+)-noradrenaline and (-)-isopropyladrenaline. Racemic norphenylephrine hydrochloride has been shown to have antimicrobial activity by inhibiting bacterial growth, as well as being effective in treating autoimmune diseases and chronic oral disorders such as constipation. Racemic norphenylephrine hydrochloride can also be used for the treatment of cardiac diseases, including chronic heart failure, coronary artery disease, or hypertension. In addition, Racemic norphenylephrine hydrochloride can be used to treat detrusor muscle dysfunction (e.g., urinary incontinence).

    Formula:C8H12ClNO2
    Purezza:Min. 95%
    Peso molecolare:189.64 g/mol

    Ref: 3D-IN27563

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  • 5-Desbromo, 5-chloro brimonidine

    CAS:

    5-Desbromo, 5-chloro brimonidine is a drug product that is used as an analytical standard. It has been shown to be metabolized by CYP3A4 and CYP2D6 enzymes.

    Formula:C11H10ClN5
    Purezza:Min. 95%
    Peso molecolare:247.68 g/mol

    Ref: 3D-RDA14746

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  • Tc 1698 dihydrochloride

    CAS:

    Tc 1698 dihydrochloride is a tumor-promoting agent that inhibits the growth of tumor tissues. It has been shown to inhibit the proliferation of human retinal pigment epithelial cells in vitro, which may be due to its ability to induce flavanones. Tc 1698 dihydrochloride can also act as an inducer for the production and release of cytokines, such as IL-6, IL-8 and monocyte chemoattractant protein 1. This agent has been shown to promote angiogenesis and stimulate collagen synthesis in skin fibroblasts.

    Formula:C13H20Cl2N2
    Purezza:Min. 95%
    Peso molecolare:275.21 g/mol

    Ref: 3D-MGB58706

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  • 6-o-Desmethyl moxonidine

    CAS:

    6-O-Desmethyl moxonidine is a drug product that is a metabolite of the parent compound, moxonidine. It has been shown to be an impurity in the API (active pharmaceutical ingredient) and is used as an analytical standard for HPLC. 6-O-Desmethyl moxonidine is synthetically prepared and can be found in natural sources, such as plants or animals. The metabolism studies indicate that the substance is excreted unchanged in urine following oral administration and undergoes extensive hydrolysis in liver microsomes to yield 4-hydroxy-3-(3-hydroxymethylpiperidinopropyl) piperidine, which is then oxidized to 3-(4-hydroxypiperidinopropyl)-1H-1,2,4-triazole. This product may cause skin irritation.

    Formula:C8H10ClN5O
    Purezza:Min. 95%
    Peso molecolare:227.65 g/mol

    Ref: 3D-CPA45733

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  • (1R,2R)-1-(M-Hydroxyphenyl)-2-amino-1-propanol

    Prodotto controllato
    CAS:

    Please enquire for more information about (1R,2R)-1-(M-Hydroxyphenyl)-2-amino-1-propanol including the price, delivery time and more detailed product information at the technical inquiry form on this page

    Formula:C9H13NO2
    Purezza:Min. 95%
    Peso molecolare:167.2 g/mol

    Ref: 3D-WAA48043

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  • Steptonigrin

    CAS:

    Streptonigrin is an anticancer drug that is derived from the bacterium Streptomyces flocculus. It has been shown to induce apoptosis in cancer cells by inhibiting various kinases, including cyclin-dependent kinases and protein kinases. Streptonigrin has been found to be effective against a variety of tumors, including those of Chinese hamster ovary cells and human urine-derived cancer cells. This inhibitor analog also has a potent inhibitory effect on tumor growth in vivo.

    Formula:C25H22N4O8
    Purezza:Min. 95%
    Peso molecolare:506.5 g/mol

    Ref: 3D-ETB89379

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  • N-[[2-[[[4-[[[(Hexyloxy)carbonyl]amino]carbonyl]phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-2-pyridinyl-β-alanine ethyl ester

    CAS:
    This is an analytical standard for the impurity N-[[2-[[[4-[[(hexyloxy)carbonyl]amino]carbonyl]phenyl]amino]-methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-2-pyridinyl-β-alanine ethyl ester. It has a purity of >98% by HPLC and is available in quantities of 5g.
    Formula:C34H40N6O6
    Purezza:Min. 95%
    Peso molecolare:628.7 g/mol

    Ref: 3D-IGC23840

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  • Terbutaline impurity b

    CAS:

    Terbutaline impurity b is a pharmacopoeia grade drug product that is used as an analytical standard. It is also used in the synthesis of terbutaline, which is a drug that has been approved by the FDA to treat bronchospasm, asthma and other lung disorders. Terbutaline impurity b may be found in natural sources or may be synthesized. This impurity can be custom synthesized using HPLC-grade reagents and can be obtained at high purity levels.

    Purezza:Min. 95%

    Ref: 3D-IT182020

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  • N-(4-Amino-6,7-dimethoxyquinazol-2-yl)-N-methylpropylenediamine formamide hydrochloride

    CAS:

    N-(4-Amino-6,7-dimethoxyquinazol-2-yl)-N-methylpropylenediamine formamide hydrochloride is an impurity in the synthesis of N-(4-amino-6,7-dimethoxyquinazol-2-yl)-N'-methylpropylenediamine formamide hydrochloride. It is a white solid that can be used as an analytical reference standard for HPLC. It has been detected in the urine of people taking this drug and can be used to identify the presence of this drug in urine samples.

    Formula:C14H17N5O2·HCl
    Purezza:Min. 95%
    Peso molecolare:323.78 g/mol

    Ref: 3D-IA156915

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  • Dioctyl carbonate

    CAS:

    Dioctyl carbonate is a pharmaceutical preparation used to treat skin conditions. It is a fatty acid ester of carbonic and carbonyl groups in which the two esters are in the same molecule. Dioctyl carbonate is a reaction product obtained by reacting an inorganic acid, such as hydrochloric acid or sulfuric acid, with an alcohol containing two hydroxyl groups and one double bond. This reaction may be facilitated by heating. The film-forming polymer may be polyvinylpyrrolidone, polyvinyl alcohol, or polyacrylic acid. Dioctyl carbonate has been shown to stimulate colony-stimulating factor production and inhibit the proliferation of human epidermal keratinocytes.

    Formula:C17H34O3
    Purezza:Min. 95%
    Colore e forma:Clear Liquid
    Peso molecolare:286.4 g/mol

    Ref: 3D-BAA68031

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  • L(+)-2-Amino-5-phosphonovaleric acid

    CAS:

    L-2-Amino-5-phosphonovaleric acid is an inhibitory neurotransmitter that binds to the GABAA receptor. It is used in the treatment of bladder disorders, such as urinary frequency, urgency, and incontinence. L-2-Amino-5-phosphonovaleric acid has been shown to have a depressant effect on the central nervous system and can cause symptoms such as nausea, vomiting, and headache. This drug also has antimicrobial properties due to its ability to inhibit bacterial enzyme activities. L-2-Amino-5-phosphonovaleric acid blocks glutamate receptors in mouse hippocampal cells by binding the alpha1 subunit of the GABAA receptor. This prevents the influx of calcium ions into cells and inhibits phosphorylation of protein kinase C. L(+)-2-Amino-5-phosphonovaleric acid also inhibits pentosan polysulfate sodium,

    Formula:C5H12NO5P
    Purezza:Min. 95%
    Peso molecolare:197.13 g/mol

    Ref: 3D-EDA05567

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  • Genistein 4’-β-D-glucuronide

    CAS:

    Genistein 4’-β-D-glucuronide is an isoflavonoid that is a natural product of soy and red clover, with estrogenic properties. It has been shown to have the ability to bind to estrogen receptors and inhibit the growth of breast cancer cells. Genistein 4’-β-D-glucuronide has been shown to inhibit the production of estrone sulfate in human breast cells, which may be due to its ability to act as an estrogen receptor antagonist. The isoflavonoid genistein also binds to and inhibits the activity of DNA topoisomerase II enzymes in human breast cells.

    Formula:C21H18O11
    Purezza:Min. 95%
    Peso molecolare:446.4 g/mol

    Ref: 3D-VJA08407

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  • Ergosterone

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    CAS:

    Ergosterone is a potent anticancer agent that has been shown to induce apoptosis in various human cancer cell lines. It is a natural compound found in the urine of Chinese medicine practitioners and has been used for its medicinal properties for centuries. Ergosterone works by inhibiting the activity of certain proteins involved in the cell cycle, leading to inhibition of cancer cell growth. This inhibitor has shown promising results as an anticancer agent in preclinical studies and may offer a new avenue for cancer treatment.

    Formula:C28H42O
    Purezza:Min. 95%
    Peso molecolare:394.6 g/mol

    Ref: 3D-SAA39857

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