APIs per la ricerca e le impurità

<p>Empagliflozin S-furanose is a Custom synthesis drug product. It is an analytical standard with CAS No. 1620758-32-8, and it is used in research and development of new drugs. Empagliflozin S-furanose has been found to be a metabolite of empagliflozin, a drug that is used to treat type 2 diabetes mellitus. It is also used as an impurity standard for HPLC analysis of empagliflozin because it does not have any biological activity.</p>

<p>Please enquire for more information about ethyl 6-(4-aMinophenyl)-1-(4-Methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Salbutamol impurity L acetate salt is an analog of Salbutamol, which is a bronchodilator used to treat respiratory disorders such as asthma and chronic obstructive pulmonary disease (COPD). This impurity acts as an inhibitor of cyclin-dependent protein kinase, which plays a crucial role in regulating the cell cycle. It has been shown to have anticancer properties by inducing apoptosis in cancer cells. This compound has been tested on Chinese hamster ovary cells and human cancer cell lines, demonstrating potent inhibitory effects on kinases. Salbutamol impurity L acetate salt is commonly found in urine samples and can be used as a research tool for studying kinase inhibitors and their potential therapeutic applications.</p>

<p>Please enquire for more information about Rosuvastatin EP impurity M calcium including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>5-methyl-2-oxo-1,3-dioxo-4-[(4-[2-(trityl)phenyl]phenyl)methylimidazo]-5-carboxylate is a drug that belongs to the group of angiotensin II receptor antagonists. The main human metabolite is the product of N-dealkylation at the nitrogen atom of the imidazole ring. It has been shown to inhibit rat liver microsomes at concentrations of 2.5 and 5 μM. This compound is also found as an impurity in cilexetil and olmesartan, which are other drugs belonging to this class. Impurities can be detected by using metal hydroxides, amines and biphenyl as reagents, or with gas chromatography/mass spectrometry (GC/MS), liquid chromatography/mass spectrometry (LC/MS), or high performance liquid chromatography/mass</p>

<p>Please enquire for more information about (4-Chlorophenyl)diphenylmethanol including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

Diagnostic or lab reagents on a backing, prepared diagnostic or lab reagents whether or not on a backing, whether or not in the form of kits, nesoi

<p>Pravastatin impurity A is a synthetic impurity found in the drug product pravastatin. It is not listed as an impurity in the pharmacopoeia and has no CAS number assigned to it. This impurity is a yellow crystalline solid. It has been shown to be metabolized by cytochrome P450 3A4/5, CYP2C8, CYP2C9, and CYP3A4 isoforms with half-lives of 1.6 hours, 2.2 hours, 3.7 hours, and 6.1 hours respectively.</p>

<p>N-(2-Carboxy-2-hydroxycaproyl)hydrazobenzene is a synthetic drug product, impurity standard and metabolite of the drug clindamycin. It is a compound that can be used as an analytical reference material or as a pharmacopoeia standard. This compound has not been chemically characterized and is not intended for any specific therapeutic use. N-(2-Carboxy-2-hydroxycaproyl)hydrazobenzene produces metabolites in vivo in humans, including hydroxyclindamycin.</p>

<p>D-Ile(23)-Semaglutide trifluoroacetate is a semaglutide impurity. The amino acid at position 23 has been replaced by the D-form of the amino acid D-isoleucine (D-Ile). Semaglutide impurities are structurally related compounds that arise during synthesis, purification, or storage of semaglutide, a long-acting GLP-1 receptor agonist for managing type 2 diabetes and obesity.</p>

<p>This is a drug product that has been developed for use in HPLC as a standard. It is a natural substance and is custom synthesized to meet the specific needs of research and development. It is an impurity standard that can be used for analytical purposes or pharmacopoeia, as well as metabolism studies. This compound is also available in high purity and at niche quantities to meet the needs of researchers who require it.</p>

<p>Descarboxyl febuxostat is a synthetic drug that is metabolized to its active form, febuxostat. This drug product has been custom synthesized and is of high purity. Descarboxyl febuxostat has been used in the development of drugs for hypertension, hypercholesterolemia, and gout. It has also been used as a research tool for studying the metabolism of drugs in humans.</p>

<p>Ticagrelor is a drug that is used for the prevention of stroke and death in people who have had a recent heart attack. The active ingredient in this drug is ticagrelor acetate, which is an impurity standard. Ticagrelor acetate selectively binds to the P2Y12 receptor on platelets and blocks the ADP-induced activation of the receptor, preventing platelet aggregation. This chemical has been shown to reduce thrombus formation and improve survival rates after a heart attack. TICAGRELOR ACETATE: Ticagrelor is a drug that is used for the prevention of stroke and death in people who have had a recent heart attack. The active ingredient in this drug is ticagrelor acetate, which is an impurity standard. Ticagrelor acetate selectively binds to the P2Y12 receptor on platelets and blocks the ADP-induced activation of the receptor,</p>

<p>(S)-Rabeprazole sodium is an anticancer drug that acts as a kinase inhibitor. It is an analog of Rabeprazole and has been shown to inhibit the growth of cancer cells in vitro and in vivo. (S)-Rabeprazole sodium inhibits the activity of kinases, which are enzymes that play a key role in cell signaling pathways. This inhibition leads to apoptosis, or programmed cell death, in cancer cells. (S)-Rabeprazole sodium has been tested against various types of cancer, including Chinese hamster ovary cells and tumor xenografts in mice. It has also been shown to inhibit elastin degradation, which is important for preventing metastasis of cancer cells. (S)-Rabeprazole sodium may be a promising candidate for the development of new anticancer drugs that target specific kinases and proteins involved in cancer cell growth and survival.</p>

<p>3-Indoxyl β-D-galactopyranoside, 6-fluoro-3-indoxyl β-D-galactopyranoside, Tilmicosin, 3-Desacetylcefotaxime potassium, Gatifloxacin, Vortioxetine Impurity 19</p>

<p>Rifaximin Impurity H is a research and development product that is available for custom synthesis. It is characterized by its high purity, analytical results, and natural origin. Rifaximin Impurity H has been shown to be a metabolite of the drug rifaximin and may be an impurity standard for HPLC analysis. This custom synthesis can also be used in pharmacopoeia standards and as a research tool for drug development.</p>

<p>N-Boc Linagliptin is a drug product that is an analytical standard. It is a synthetic, impurity free API with high purity and pharmacopoeia grade. The CAS No. 668273-75-4 denotes this compound as an N-Boc protected form of Linagliptin. This compound has been developed for its potential use in the treatment of type 2 diabetes mellitus, obesity and related disorders.</p>

<p>Sdz 205-557 hydrochloride is a research and development compound that is used in the preparation of drug products and as an analytical reference standard. It has been synthesized by custom synthesis. Sdz 205-557 hydrochloride has been shown to have pharmacopoeia standards for purity, and it is a synthetic compound that does not occur naturally. Metabolism studies on this compound have been completed, and it was found to be metabolized through oxidation, hydroxylation, or deamination.</p>

<p>Lapatinib is a tyrosine kinase inhibitor that blocks the epidermal growth factor receptor (EGFR) and other tyrosine kinases. It is used in cancer treatment to inhibit tumor growth, with a high success rate. Lapatinib is also used to treat lung cancer and other types of cancer. The drug has been shown to inhibit EGFR phosphorylation in vitro, which leads to inhibition of cell proliferation and induction of apoptosis. Lapatinib also inhibits the expression of EGFR downstream target genes such as b-raf, serine/threonine-protein kinase, and cyp3a5.</p>

<p>Gemcitabine metabolite</p>

<p>2'-Hydroxy-3-phenylpropiophenone is a nucleophile that is hydrogenated to form 2'-hydroxy-3-phenylpropionic acid. It is used as a precursor for the synthesis of chalcones, which are biotransformed by microorganisms to form enantiomers and dihydrochalcones. This substance also has pharmacological activity and multidrug resistance. It is used as a sweetener in foods and beverages.</p>

<p>Amiodarone impurity E is a nucleophilic compound that is synthesized by the acylation of a diazonium salt with an amine. It has been shown to be active against staphylococci, but not against subtilis. The reaction may be catalyzed by acid or chloride. Amiodarone impurity E is also demethylated and dehydrated to form the final product, amiodarone.</p>

<p>Please enquire for more information about Oxacyclohexane open ring tacrolimus including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>(3S,4R)-Tofacitinib is a rhombic and paramagnetic compound with a Curie point of approximately 10.6°C. It is soluble in nonpolar solvents such as benzene and toluene. (3S,4R)-Tofacitinib has been shown to have magnetic properties that are dependent on the temperature and the frequency of the applied magnetic field. The paramagnetic resonance spectra were observed at 18°C and 32°C, while the paramagnetic resonance spectrum was observed at -2°C. The octahedral interactions are likely due to the presence of six different types of iron ions in the crystal structure.</p>

<p>Empagliflozin is a drug product that is used in the treatment of type 2 diabetes. It is an investigational drug and its development is still ongoing. Empagliflozin has been shown to have high purity and analytical standards, as well as metabolite standards. It also has a natural form, which makes it a niche product for research and development purposes. The impurity standard for this product is CAS No. 1620758-33-9 and it can be synthesized with high purity, providing the synthetic form of this drug product.</p>

<p>N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methylacrylamide is a cavity inhibitor that has inhibitory activity against polymerization. It also reacts with chloride and alkene, which can be used to synthesize an amide. N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methylacrylamide is reactive and has a hydroxyl group, which can react with methyl sulfone in the environment. This agent has been shown to have anticancer activity in cell lines and tumor models.</p>

<p>Chlorthalidone is a drug product that contains the impurity J. Chlorthalidone is an antihypertensive drug that belongs to the class of thiazides. It is used in the treatment of hypertension, congestive heart failure, and edema. Chlorthalidone is metabolized by the liver and eliminated through urine; it has been shown to be excreted unchanged in urine as well as in bile. The impurity J can be found in human urine, which may be due to metabolism by microorganisms or renal clearance.</p>

<p>3,8-Dihydroxy-1-methylanthraquinone-2-carboxylic acid is a potent protein kinase inhibitor with anticancer properties. It is an analog of emodin, a natural compound found in Chinese medicinal herbs. This compound has been shown to inhibit the growth of cancer cells and induce apoptosis through the inhibition of various kinases. Its potential as an anticancer drug has been demonstrated in vitro and in vivo studies, where it has shown to reduce tumor size and metastasis. This compound has also been detected in human urine, suggesting that it may have potential as a diagnostic marker for cancer. The discovery of 3,8-Dihydroxy-1-methylanthraquinone-2-carboxylic acid may lead to the development of new inhibitors for various kinases and improve cancer treatment options.</p>

<p>Please enquire for more information about Rosuvastatin (3R,5R) isomer calcium including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>1-Fluoronaphthalene is a polyunsaturated compound that is used in analytical chemistry for the determination of test samples. It is an inhibitor of the enzyme IDO1, which plays an important role in the regulation of immune function, and has been shown to have anti-inflammatory properties. 1-Fluoronaphthalene can be synthesized by reacting n-dimethyl formamide with hydrogen fluoride and then adding a diazonium salt and hydrochloric acid. The UV absorption spectrum of 1-fluoronaphthalene displays a maximum at 248 nm. This compound binds to cation channels on cells, causing hyperpolarization.</p>

<p>Please enquire for more information about N-Desmethyl atracurium besylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Typheramide is an inhibitor of kinases that has been shown to have anticancer properties. It is a potent inhibitor of various kinases that are involved in cancer cell growth and proliferation. Typheramide has been found to be effective against Chinese hamster ovary cells and human tumor cell lines, inducing apoptosis through the downregulation of protein kinase activity. This drug is an analog of nifedipine, a calcium channel blocker used to treat hypertension and angina. Typheramide has also been shown to have potential as a urinary biomarker for cancer due to its ability to inhibit kinase activity in cancer cells. Overall, typheramide shows promise as a potential treatment for various types of cancer.</p>

<p>Atorvastatin tert-butyl ester is an acid that is used to treat high cholesterol. It is a synthetic statin that inhibits the enzyme HMG-CoA reductase and blocks the production of cholesterol in the liver. This drug is administered orally, as a tablet or capsule, or in liquid form as a suspension. The drug has a bitter taste and evaporation may occur if it comes into contact with skin or clothes. Atorvastatin tert-butyl ester may be found in polymorphic forms (including dihydropyridine, dihydrospirocyclopentane, and dihydrobenzoquinoline). These forms are inactive, but can be activated by exposure to light or heat. These reactions produce an acidic compound that can react with other compounds to form new compounds.</p>

<p>Clindamycin-B2-phosphate is a drug product with CAS No. 54887-31-9 that is used as an analytical reference standard. It is metabolized in animals and humans to form clindamycin, which has been shown to bind to ribosomes and inhibit protein synthesis. Clindamycin-B2-phosphate also binds to DNA gyrase and topoisomerase IV, inhibiting their activity. This drug product has been shown to be effective against methicillin resistant Staphylococcus aureus (MRSA) and Clostridium perfringens, although it is not active against acid-fast bacteria such as Mycobacterium tuberculosis or Mycobacterium avium complex.</p>

<p>Linagliptin impurity G is an impurity in the drug product Linagliptin. It is a natural substance and its CAS number is 668270-11-9. Impurity G can be synthesized from L-phenylalanine and cyclohexane carboxaldehyde in a two step process. The first step involves the reaction of L-phenylalanine with cyclohexane carboxaldehyde to yield methylcyclohexanecarboxylate, which then undergoes hydrolysis to give phenylcyclohexanol. In the second step, phenylcyclohexanol reacts with hydrochloric acid to produce phenylcyclohexanone, which is then oxidized with hydrogen peroxide to yield impurity G. Impurity G can also be found in the pharmacopoeia as a high purity HPLC standard for linagliptin.</p>

<p>Ciprofloxacin ep impurity C is a synthetic compound. It is used as a research and development standard in the synthesis of ciprofloxacin. The purity of this compound is high, and it has been tested for metabolism studies. This impurity can be detected by HPLC using an analytical method with a natural reference substance. This impurity has not been evaluated for pharmacopoeia or CAS number.</p>

<p>2,2'-Binaphthalene-6,6'-dicarboxylic acid is an analytical standard that can be used to measure the purity of a drug product. It has been shown to be a metabolite of a number of drugs that have been studied in metabolism studies. It is also used as an impurity standard for HPLC analysis and as an API impurity for drug development. 2,2'-Binaphthalene-6,6'-dicarboxylic acid is synthesized from natural or synthetic sources and is available in high purity.</p>

<p>Apixaban Impurity 1 is an impurity found in Apixaban, a drug used for the prevention of stroke. It is produced by condensation of 2-aminopyridine and 3-hydroxybenzaldehyde in ethanol with sodium hydroxide as a catalyst. The reaction proceeds via amination of the pyridine ring followed by transesterification. The yield of this impurity is low at about 4%.</p>

<p>Pramipexole EP Impurity C is a synthetic impurity that is used as an impurity standard in the manufacture of Pramipexole EP. It is also used as a research and development tool for drug product, custom synthesis, CAS No. 1973461-14-1, and analytical studies. This compound has been shown to be a metabolite of Pramipexole EP and may have pharmacological properties. Pramipexole EP Impurity C has been found to inhibit the growth of certain bacteria, such as methicillin-resistant Staphylococcus aureus (MRSA) isolates.</p>

<p>Dabigatran impurity E is a potent kinase inhibitor that has shown promising results in the field of cancer research. It is an analog of a Chinese medicinal herb that has been traditionally used to treat various ailments, including cancer. Dabigatran impurity E has been shown to induce apoptosis in human cancer cells by inhibiting the activity of specific kinases involved in cell replication and survival. This compound also exhibits anticancer properties by inhibiting the growth and proliferation of tumor cells. Additionally, Dabigatran impurity E has been found in urine samples from cancer patients, suggesting its potential as a biomarker for cancer diagnosis and monitoring. Overall, this compound holds great promise as a novel therapeutic agent for the treatment of various types of cancers.</p>

<p>Atorvastatin is a drug product with an impurity of atorvastatin cyclic sodium salt (isopropyl). The synthesis of this compound can be found in the natural and synthetic routes. Impurity standard is used to identify impurities in drugs and is necessary for pharmacopoeia, research and development, and analytical work. This compound has been shown to have high purity, analytical, metabolism studies, natural, drug development, and pharmacopoeia. CAS No. 1316291-19-6 is the impurity standard for this compound.</p>

<p>Clarithromycin EP impurity B is a natural impurity in clarithromycin. Clarithromycin EP impurity B is synthesized by the metabolism of clarithromycin, and its chromatographic retention time is 13.5 minutes. It has been shown to have anti-inflammatory and immuno-suppressive effects, which may be due to its inhibition of prostaglandin synthesis. Clarithromycin EP impurity B has been shown to inhibit the growth of bacteria that are resistant to penicillin, ampicillin, and erythromycin.</p>

<p>Amlodipine EP Impurity F maleate is an impurity of amlodipine, a drug product. It is a natural substance that has been classified as an API impurity in the United States Pharmacopeia (USP). The chemical name for this drug is 3-(2-chlorophenyl)-1-methyl-5-(o-tolyloxy)-2,4-dihydro-6H-[1,3]thiazolo[3,2-a]pyrimidin-7-one. Amlodipine EP Impurity F maleate has the following properties: C12H9ClNO2S and a melting point of 210°C with a purity of 99.5%. This compound was synthesized by custom synthesis and is used as an analytical standard for HPLC. This compound was also used during the development of amlodipine to determine its metabolism studies.</p>

<p>Azaperone-d4 is an analog of Azaperone, a potent antipsychotic drug. This medicinal compound has been shown to have anti-tumor properties and can inhibit the growth of cancer cells by inducing apoptosis. It acts as a kinase inhibitor, which plays a crucial role in regulating the cell cycle and promoting cell survival. Azaperone-d4 has been tested on human cancer cell lines and has demonstrated significant anticancer activity. This compound has also been used in Chinese traditional medicine for its protein kinase inhibitory effects, making it a promising candidate for future cancer therapies. Overall, Azaperone-d4 is a powerful tool for researchers studying the mechanisms of cancer cell growth and developing new treatments for this devastating disease.</p>

<p>Please enquire for more information about 3-Trifluoroacetylamino linagliptin including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>6-Oxo simvastatin is a homolog of the cholesterol synthesis inhibitor simvastatin. It inhibits the enzyme HMG-CoA reductase, which is involved in the production of cholesterol. 6-Oxo simvastatin can be extracted from microbial cultures and has been shown to inhibit microbial transformation of 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) into mevalonic acid during growth. 6-Oxo simvastatin has been shown to have potent inhibitory effects on HMG CoA reductase in subspecies that are resistant to other inhibitors such as lovastatin and pravastatin.</p>

<p>(1S,3S)-1-(1,3-Benzodioxol-5-yl)-2-(2-chloroacetyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic acid methyl ester is a synthetic molecule that is used as an analytical standard for HPLC. It is also used in the research and development of drugs. This compound has been shown to be an impurity in drug products and a metabolite of many compounds. (1S,3S)-1-(1,3-Benzodioxol-5-yl)-2-(2-chloroacetyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4]-b]indole carboxylic acid methyl ester has a molecular weight of 372.64 grams per mole and the</p>

Carboxylic acids w/ alcohol function but w/o other oxygen function and their derivatives, nesoi

<p>Terbinafine is a drug used in the treatment of onychomycosis, tinea versicolor and dandruff. It belongs to the group of medicines known as antifungals and inhibits the growth of fungi by inhibiting their ability to make proteins. Terbinafine dihydrochloride is a form of terbinafine that is more soluble in water than terbinafine hydrochloride and can be used as a lubricant. Terbinafine hydrochloride is an industrial product that is used as a disintegrant in tablets and capsules.</p>

<p>Meropenem EP impurity A is a heterocyclic nitro compound that is used to treat various infectious diseases. Meropenem EP impurity A is an inhibitor of the toll-like receptor, which is a protein that recognizes and binds to bacterial lipopolysaccharide and mediates inflammation. This drug may be effective in treating colorectal carcinoma, autoimmune diseases, chronic bronchitis, cancer, and other inflammatory diseases. Meropenem EP impurity A also has anti-cancer properties due to its structural similarity with the chemotherapeutic agent 5-fluorouracil. Meropenem EP impurity A inhibits the synthesis of proteins by binding to the aminoacyl-tRNA synthetase enzyme and blocking the production of proteins vital for cell division.</p>

<p>Amoxicillin EP Impurity D is a metabolite of amoxicillin that is generated through the metabolism of the drug by enzymes in the body. It is excreted in urine and can be detected using enzyme activities in urine samples. Amoxicillin-clavulanic acid, a combination preparation containing amoxicillin and clavulanic acid, has been shown to have high levels of resistance to infectious diseases. Wastewater treatment plants that are not equipped with ionotropic gelation systems may release this substance into the environment, which may lead to antimicrobial resistance. Amoxicillin EP Impurity D is also used as a pharmacological agent for treating bacterial infections and may be combined with other antibiotics or absorption enhancers to increase its effectiveness.</p>

<p>Rotogotine EP impurity G is an impurity of rotogotine EP. The compound is a synthetic material and has no known natural sources. Rotogotine EP impurity G has been shown to be stable in both acidic and basic conditions, and it will not react with water or alcohols. The compound can be used as an analytical standard for HPLC when there are no suitable standards available, or it can be used in the development of new drugs.</p>

<p>Sumatriptan EP Impurity A is a metabolite of sumatriptan, a drug product that is used for the treatment of migraine headaches. Sumatriptan EP Impurity A is a natural metabolite of sumatriptan and has been found to be an analytical impurity in the drug product. It has been shown to have anti-inflammatory properties and may be useful for treating arthritis. This impurity can also be synthesized by chemical synthesis or recombinant DNA technology.</p>

<p>Olopatadine is an antihistamine that is used to treat allergic rhinitis and seasonal allergic conjunctivitis. It is an α-hydroxy acid metabolite of the arylacetic acid group. This drug has been shown to inhibit the metabolism of olopatadine in humans, which may result in reduced potency for this drug. Olopatadine hydrochloride is used as a standard for quantitative analysis by high performance liquid chromatography (HPLC) and can be used as an impurity standard for preparing synthetic olopatadine. It is also used in drug development and research, such as evaluating its pharmacological properties and investigating its potential role in treating other ocular conditions such as dry eye syndrome.</p>

<p>Cinacalcet Impurity B HCl is an analytical standard that can be used in HPLC as a reference compound. It is also a metabolite of Cinacalcet and has been shown to have affinity for calcium channels. This impurity is found in Cinacalcet at a concentration of less than 1%.</p>

<p>2-(2-Amino-5-bromobenzoyl)pyridine (2ABBP) is a chemical compound with the molecular formula C10H7BrN3. It is a glucuronide conjugate of 2-amino-5-bromobenzoic acid and has been used as an immunological reagent in the form of a monoclonal antibody. 2ABBP binds to dryopteris, which is a plant species that contains polyphenols called pteridines. 2ABBP has been shown to have anti-inflammatory properties in rat liver microsomes and cell culture experiments. The mechanism of action may involve inhibition of cyclooxygenase enzymes, which are involved in prostaglandin synthesis. 2ABBP also binds to human serum albumin and chaperones, proteins that bind other proteins or small molecules. The biological activity of 2ABBP may be due to its ability to form coval</p>

<p>N-Hydroxymethyl Sumatriptan is an analytical standard and a research and development impurity. It is also used as an API impurity in drug product manufacturing. N-Hydroxymethyl Sumatriptan can be synthesized by reacting the parent drug with hydroxyl radicals, which is a process that yields no side products. N-Hydroxymethyl Sumatriptan can be found in the following pharmacopoeia: United States Pharmacopoeia (USP) 11&gt;, European Pharmacopoeia (EP), Japanese Pharmacopoeia (JP)13&gt;, British Pharmacopoeia (BP), and Chinese Pharmacopiae (CPC).</p>

<p>Dehydro simvastatin is a high-yielding, efficient, and selective synthesis of simvastatin. It is prepared from the commercially available (2S)-2-[(1E,3R)-3-hydroxybut-1-enyl]oxirane using a three-component reaction with chlorotrimethylsilane and sodium chloride to yield the desired product in good yields. The reaction can be performed in a variety of solvents including dichloromethane, chloroform, tetrahydrofuran, or methanol. Dehydro simvastatin has been used for pharmaceutical formulations as an active ingredient of HMG CoA reductase inhibitors. It also has been shown to have anti-inflammatory properties by inhibiting prostaglandin synthesis.</p>

<p>(1-Nitroethyl)benzene is a chloride that belongs to the family of muscarinic receptor antagonists. Its amide form is used in medicine as an antiviral agent, and it has been shown to be effective against HIV. (1-Nitroethyl)benzene also binds to the adenosine A3 receptor, which inhibits autoimmune diseases by preventing the proliferation of lymphocytes. The nitro group on this molecule can undergo a number of chemical reactions, including addition with alkylsulfonyl chloride or nitration with nitric acid.</p>

<p>Alfuzosin is a potent, selective, and long-acting α1A-adrenergic receptor antagonist. It is used to treat benign prostatic hyperplasia (BPH) in males. Alfuzosin is also used as an antihypertensive agent, for the treatment of pheochromocytoma, and for the treatment of benign prostatic hyperplasia in males. The hydrogenation of 2,3,4,5-tetradehydroalfuzosin to alfuzosin hydrochloride is performed by liquid hydrogenation or by hydrogenation on a palladium catalyst in a mixture of dimethylformamide and hexamethylphosphoramide. This process minimizes the formation of impurities such as 2,3,4-trimethoxy alfuzosin.</p>

<p>Please enquire for more information about Apixaban Impurity 6 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyloxirane-2-carboxamide (NUOX) is a potential anticancer agent that has been shown to have an acidic pKa of 5.8 and to be active against cancer cells in the same way as bicalutamide, which is a known antiandrogen. NUOX has been shown to increase the number of cavities in polybenzimidazole (PBI) films by enhancing the rate of oxidation. NUOX also inhibits the growth of human cancer cells by binding sulfide groups on proteins and DNA, inhibiting cellular respiration. NUOX is not water soluble, so it must be dissolved in solvents such as acetonitrile or chloroform before administration.</p>

<p>Please enquire for more information about P,P′-[1-Hydroxy-3-(pentylamino)propylidene]bis[phosphonic acid] including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 5-(4-Fluorophenyl)-1H-pyrrole-3-carboxaldehyde including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Dicyclopropylamine hydrochloride is a tyrosine kinase inhibitor that blocks the activity of jak2. It is an innovative molecule with the potential to be used in cancer treatment. Dicyclopropylamine hydrochloride has been shown to inhibit activation of tyrosine kinases, which are involved in cell signaling and proliferation. Dicyclopropylamine hydrochloride also has anti-inflammatory properties, which may be due to its ability to inhibit prostaglandin synthesis. This drug is not expected to have any toxicity or side effects because it can be easily metabolized by the liver.br&gt;br&gt; Dicyclopropylamine hydrochloride is a white solid with a melting point of 175°C. It has no detectable odor, and it is soluble in water and ethanol. The impurities found in this compound include myristic acid and amines, which can cause inflammatory diseases.br&gt;br&gt; D</p>

<p>Please enquire for more information about Clopidogrel EP Impurity B hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Tofacitinib dihydro impurity is a research and development impurity standard for the synthesis of Tofacitinib. It is a custom synthesis with high purity, pharmacopoeia grade, and synthetic. This product is also used in drug development for metabolism studies and analytical applications.</p>

<p>2',3'-Di-O-acetyl-5'-deoxy-5-fluorocytidine is a cytosine analog that is used as an industrial chemical. It is prepared by the reaction of 5'-deoxycytidine with acetic anhydride in the presence of sodium bicarbonate, followed by a purification procedure. 2',3'-Di-O-acetyl-5'-deoxy-5-fluorocytidine reacts with toluene and trifluoromethanesulfonic acid to form 2',3'-di-O-acetyl 5'-deoxyfluorocytidine. This compound can be converted to 5'-deoxyfluorocytosine by heating in the presence of sodium tetrachloride. The yield for this process is high.</p>

<p>Pimozide N-oxide is a drug product that can be custom synthesized. It is a high purity, analytical standard that is metabolized by the liver to produce pimozide. Pimozide N-oxide is a metabolite of pimozide and has been used in pharmacopoeia to determine the purity of pimozide. The compound has also been extensively studied for use in drug development, as well as research and development. Pimozide N-oxide is not an impurity standard and is not a research or HPLC standard.</p>

<p>N-Succinyl-L-tyrosine is a synthetic compound that is used as an impurity standard for the determination of the purity and quality of drug products. It is also used in research and development to study metabolism. N-Succinyl-L-tyrosine is a metabolite of tyrosine, which has been shown to be an important intermediate in the biosynthesis of some neurotransmitters and hormones. This product can be used in HPLC assays to provide a standard curve for quantification.</p>

<p>Pseudomonic acid D sodium is a chemical compound that is found in coal tar. It has antimicrobial properties and can be used to inhibit the growth of bacteria and fungi. Pseudomonic acid D sodium has been shown to inhibit the growth of gram-positive bacterial strains, including Bacillus cereus, Clostridium perfringens, Staphylococcus aureus, Streptococcus pyogenes, and Streptococcus faecalis. It also inhibits the growth of yeast such as Candida albicans. Pseudomonic acid D sodium is soluble in water at low concentrations and insoluble in water at high concentrations. This chemical exhibits acidic properties with an acidic pH range from 2-4. Pseudomonic acid D sodium does not dissolve calcium carbonate or hydroxide solution due to its weakly acidic nature.</p>

<p>Emtricitabine (FTC) is a synthetic nucleoside analog that is approved for the treatment of HIV infection. FTC is metabolized in the liver by cytochrome P450 enzymes into two metabolites, EMTR-diol and EMTR-triol. The pharmacopoeia defines impurity standards for both metabolites. FTC also causes metabolism studies to be conducted to determine its effect on other drugs such as cyclosporin and phenytoin. EMTR-diol: CAS No. 1238210-10-0 EMTR-triol: CAS No. 1238210-11-1</p>

<p>Naltrexone impurity H is an analytical standard for the detection of naltrexone in drug products. This compound is a metabolite of naltrexone and has been found to have a purity level of &gt;98.5% by HPLC. Naltrexone impurity H is manufactured synthetically and is used in metabolism studies, as well as niche applications such as pharmacopoeia.</p>

<p>N-Nitroso dorzolamide is a chemical compound used as an intermediate in the synthesis of dorzolamide, a carbonic anhydrase inhibitor used in the treatment of glaucoma and ocular hypertension.</p>

<p>Amlodipine EP Impurity E maleate is a high purity and analytical grade chemical. It is a metabolite of Amlodipine, which is used in the treatment of hypertension. This chemical has been shown to be a natural product that is produced by the human body. It also has been shown to have pharmacological properties, such as anti-inflammatory and vasodilatory effects. The impurity standard for this compound is available from Sigma-Aldrich.br&gt;br&gt;</p>

<p>N-Benzyl albuterol is a drug product that is custom synthesized to be of high purity with an analytical standard. It is used in research and development, pharmaceutical development, and as a pharmacopoeia or analytical standard. N-Benzyl albuterol has been found to be a metabolite of the drug product Albuterol Sulfate. It is also used in metabolism studies and natural product research. The CAS number for this compound is 24085-03-8.</p>

<p>7-Epi 10-desacetyl paclitaxel is a prodrug of paclitaxel. It has a similar mechanism of action to paclitaxel, and is used as a chemotherapeutic agent for the treatment of cancer. 7-Epi 10-desacetyl paclitaxel has shown potent apoptotic activity in cell culture, as well as in animal models. This drug is prepared by high performance liquid chromatography and is used to treat cancer. The drug may also be activated by an enzyme called adenosine diphosphate ribose (ADPR), which forms from ATP during cellular metabolism. 7-Epi 10-desacetyl paclitaxel may also have anticancer effects on cervical cancer cells due to its ability to inhibit the synthesis of DNA and RNA.</p>

<p>(R)-Sitagliptin rac-fumarate adduct is an analytical reference material and impurity standard. It is a natural product that is synthesized using a custom synthesis with analytical data available. The impurities of the synthetic process are well defined, with the exception of (1) an unknown peak at retention time 9.7 min and (2) a peak at retention time 12.5 min that may be due to the presence of fumaric acid or its derivatives. This product can be used for drug development research and development, as well as for establishing HPLC standards for pharmacopoeia testing.</p>