APIs per la ricerca e le impurità

<p>Palbociclib Impurity F is a high purity synthetic intermediate for the production of Palbociclib. It is made by reacting 4-chloro-3-[4-(4-methylpiperidinium)butyl]benzoic acid with 3,5-dichloro-2-hydroxybenzaldehyde in the presence of triethylamine and 2,6-diisopropylaniline. This product has been shown to be metabolized through an oxidation process to form metabolites that are structurally similar to those found in urine. The chemical structure of this impurity can be found in CAS No. 851067-56-6.</p>

<p>2-Propylimidazole-4,5-dicarboxylic acid is an organic compound with the chemical formula CH2=C(CH3)CO2H. It is a colorless solid that has been found to have inhibitory activity against locomotor activity in mice. 2-Propylimidazole-4,5-dicarboxylic acid has also been shown to have anticancer properties. The fluorescence properties of this compound are due to the presence of two quinoid moieties, which can be excited by light at 350 nm and emit light at 500 nm. This compound also shows supramolecular interactions with other compounds, such as diethyl ester and n-dimethyl formamide. 2-Propylimidazole-4,5-dicarboxylic acid crystallizes in a monoclinic space group P21/c with four molecules per unit cell and a molecular weight</p>

<p>Please enquire for more information about Mezlocillin impurity III including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>(E,Z)-Epalrestat methyl ester is a drug product that is custom-synthesized for research and development purposes. It is a natural metabolite of (E,Z)-epalrestat acid. The chemical name for this compound is 3-[(2-chlorophenyl)methyl]-N-(1H-indol-3-ylmethylene)malonamide. The molecular weight of this compound is 284.87 g/mol and it has an empirical formula of C24H27ClN2O2. It has been found to inhibit the activity of phosphodiesterase (PDE), which plays a role in the breakdown of cyclic nucleotides such as cAMP and cGMP. This product has high purity and analytical data that can be used for metabolism studies or clinical trials.</p>

<p>Deacylated alfuzosin is an impurity of alfuzosin, which is a selective alpha-1A-adrenergic receptor antagonist. It has been shown to minimize the effects of impurities in alfuzosin by binding competitively to the alpha-1A-adrenergic receptors.</p>

<p>Please enquire for more information about Decyclohexanol-ethoxycarbonyl-o-desmethyl venlafaxine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>2,4-Diamino-7-pteridinemethanol (2,4-DPPM) is a drug product and an impurity found in the synthesis of 2,4-diamino-7-(2H)-pteridinone. 2,4-DPPM is a synthetic product that can be used as an analytical standard for the determination of aminopyrine in pharmaceuticals and other organic compounds. This compound has been used in pharmacological studies to investigate its effects on various enzymes associated with metabolism. It has also been used as an impurity standard for HPLC analysis of aminopyrine.</p>

<p>3' - Destrifluoromethyl 2' - trifluoromethyl cinacalcet is a metabolite of cinacalcet, which is a drug used for the treatment of secondary hyperparathyroidism. It is an impurity in the drug product and can be identified by HPLC.</p>

<p>3-(Dimethylamino)-1-(2-thienyl)propanone hydrochloride is a sulfoxide that is used as a solvent. It has been used in the synthesis of benzylsulfoxides and solvents for the manufacture of pharmaceuticals. 3-(Dimethylamino)-1-(2-thienyl)propanone hydrochloride is also a potent compound, which is structurally similar to benzene but with an additional methyl group. 3-(Dimethylamino)-1-(2-thienyl)propanone hydrochloride has been used in the synthesis of melphalan and elemental analysis. The chloride group on its structure makes it soluble in water and organic solvents such as acetonitrile. 3-(Dimethylamino)-1-(2-thienyl)propanone hydrochloride can be synthesized by reacting nitric acid with 2-aminothiophenol and dimethylanil</p>

<p>Pyrene-13C6 is a medicinal compound that has been shown to be an effective inhibitor of apoptosis in tumor and leukemia cells. It works by inhibiting the activity of certain kinases and proteins involved in cell cycle regulation, which can lead to the death of cancer cells. Pyrene-13C6 has been tested extensively in Chinese hamster ovary cells and has been found to have potent anticancer activity. In addition, this compound has been detected in human urine, suggesting that it may have potential as a diagnostic tool for cancer detection. Overall, Pyrene-13C6 is a promising candidate for the development of new cancer therapies and diagnostic methods.</p>

<p>Diclofenac dimer impurity is a synthetic impurity that is used as a research and development, impurity standard, custom synthesis, drug product, and analytical standard. It is a high purity, CAS No. 1609187-30-5, pharmacopoeia (USP), Drug development (DSD), Metabolite (MET), niche, analytical standard. Diclofenac dimer impurity is a natural metabolite of diclofenac in humans and other animals. The chemical name for the metabolite is 2-(dichlorophenyl) propionic acid or 2-[2-chloro-4-(2,2-dichlorovinyl)phenoxy]propanoic acid. Diclofenac dimer impurity may be synthesized by reacting diclofenac with paraformaldehyde followed by hydrolysis with sodium hydroxide or potassium hydroxide. HPLC analysis</p>

<p>6-Hydroxy-2-(4-hydroxyphenyl)-benzo[b]thien-7-yl][4-[2-(1-piperidinyl)ethoxy]phenyl]methanone is a synthetic impurity standard that is used as a reference material in the analytical, natural and drug development, and metabolite studies. 6-Hydroxy-2-(4-hydroxyphenyl)-benzo[b]thien-7-yl][4-[2-(1-piperidinyl)ethoxy]phenyl]methanone has a molecular weight of 390.27 and chemical formula C26H28N2O3S. It is also referred to by its CAS number 1391054-73-1.6</p>

<p>Please enquire for more information about (R,R,S,S)-Cisatracurium dibesylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>2-(2-Fluoro-[1,1'-biphenyl]-4-yl)-2-methylmalonic acid is an analog of ginsenoside, a Chinese herbal medicine known for its anticancer properties. This compound has been shown to inhibit protein kinases, which are enzymes that play a critical role in cancer cell proliferation and survival. 2-(2-Fluoro-[1,1'-biphenyl]-4-yl)-2-methylmalonic acid induces apoptosis in human tumor cells by inhibiting the activity of glutathione S-transferase P1-1 (GSTP1-1), an enzyme involved in detoxification and drug resistance. The inhibition of GSTP1-1 leads to the accumulation of reactive oxygen species and DNA damage, ultimately resulting in cell death. This compound represents a promising class of kinase inhibitors with potential therapeutic applications for cancer treatment.</p>

<p>Remdesivir related compound 5 is a plant extract that inhibits the growth of wheat. Remdesivir related compound 5 contains allelopathy, which is the ability to inhibit the growth of other plants by releasing substances from its roots or leaves. A study was conducted in which wheat seeds were treated with extracts of this plant and it was found that there was a significant decrease in the growth of the plants. This may be due to the inhibition of protein synthesis and cell division, as shown in other studies.</p>

<p>Amoxicillin trihydrate impurity H is an impurity of amoxicillin that is a potent bactericide. The impurity has been observed to have bactericidal activity against gram-negative bacteria and gram-positive bacteria, as well as potent activity against gram-negative bacteria. The process development of this compound has shown it to be an elemental substance. It can be found in the form of a hydroxyphenyl group attached to the amoxicillin molecule. Impurities such as this one are often removed from the final product by ion exchange chromatography or other methods.</p>

<p>Tetrahydro-2-[2-(4-hydroxyphenyl)-1-methylethyl]-4,6,8-isoquinolinetriol is a synthetic compound that is used as an analytical reference standard for the detection of impurities in drugs. It is also commonly used as an impurity standard when synthesizing drugs and has been shown to be metabolized through various pathways including oxidation by cytochrome P450 enzymes. Tetrahydro-2-[2-(4-hydroxyphenyl)-1-methylethyl]-4,6,8-isoquinolinetriol is also used in drug development research and development.</p>

<p>Pravastatin 6-oxo Impurity is an impurity of Pravastatin, a drug used in the treatment of high cholesterol. The impurity has been identified through analytical methods and is characterized by HPLC analysis. This substance has been shown to be present in at least 0.1% of the drug product and may be present as a result of incomplete synthesis or a side-reaction during synthesis.</p>

<p>cis-(±)-4-[4-[4-[4-[[2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]- 2,4-dihydro-2-propyl-3H-1,2,4-triazol-3-one is a drug product that is used as a research and development tool. It is an impurity standard for HPLC. This compound has a chemical name of cis-(±)-4-[4-[4-[4-(hydroxymethyl)phenyl]-1piperazinyl]phenyl]-2, 4dihydro 2propyl 3H 1 2 4 triazol 3one. The CAS number for this compound is 7485591 7. This compound</p>

<p>Please enquire for more information about (1R,2R)-1-(M-Hydroxyphenyl)-2-amino-1-propanol including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Linezolid N-oxide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Di(N-desethyl) amiodarone hydrochloride is an impurity of Amiodarone Hydrochloride, which is a drug that is used to treat and prevent serious ventricular arrhythmias. Di(N-desethyl) amiodarone hydrochloride can be synthesized from the corresponding parent compound by desmethylation with trifluoroacetic acid. It has been shown to have a low solubility in water and it is soluble in acetones, ethers, and chloroform. This impurity can be used as a HPLC standard for the analysis of Amiodarone Hydrochloride or as an analytical reference material for other liquid chromatography methods.</p>

<p>TRV120055 is a medicinal compound that acts as a kinase inhibitor, specifically targeting the cell cycle and protein synthesis in cancer cells. It has been shown to be effective against leukemia and various types of tumors in human and Chinese hamster cell lines. TRV120055 inhibits the activity of specific proteins involved in cancer cell growth and proliferation, leading to apoptosis or programmed cell death. This compound has potential as an anti-cancer drug due to its ability to selectively target cancer cells while leaving healthy cells unharmed. Its efficacy as a cancer treatment is currently being studied in clinical trials.</p>

<p>tert-Butyl 4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazine-1-carboxylate is an impurity that is found in the production of tert-butyl 4-(4,5,6,7,8,9,10-hexahydrobenzo[a]pyrido[1,2:4,3]triazin-2(3H)-yl)piperazine-1 carboxylate. It has been used as a reference standard for HPLC. This compound is not active when administered orally and does not exhibit any pharmacological activity.</p>

<p>(R)-Norfluoxetine phthalimide is a metabolite of fluoxetine. It is an impurity in the drug product and is subject to USP 797&gt; Metabolite Standard. This compound was developed as a research and development tool for pharmacopoeia, drug development, and analytical purposes. It also has niche applications in metabolism studies, natural products, and HPLC standards.</p>

<p>5,6-Dehydro-17beta-dutasteride is a synthetic drug product that is used as an analytical standard for the determination of metabolites and impurities in pharmaceuticals. It also has been used as a natural metabolite, which can be found in human urine. 5,6-Dehydro-17beta-dutasteride is a metabolite of dutasteride, which is an antiandrogen medication for the treatment of benign prostatic hyperplasia (BPH). It is also known to inhibit the metabolism of other drugs such as ketoconazole and metoprolol.</p>

<p>Please enquire for more information about Nonanal-d18 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Ivermectin B1 aglycon is a drug product that is custom synthesized, high purity, and analytical. It is natural and synthetic and has a niche in the market. It is used for metabolic studies and drug development purposes. Its metabolite are impurities that are found in pharmacopoeia. Ivermectin B1 aglycon is a metabolite of ivermectin, which has been shown to have anti-inflammatory properties.</p>

<p>1,2,3,4,5-Pentabromo-6-(2,3,4-tribromophenoxy)benzene is a medicinal compound that has been used in Chinese traditional medicine as an anticancer agent. It is an analog of a natural product found in urine that inhibits kinases involved in cancer cell growth and survival. This compound has been shown to induce apoptosis (programmed cell death) in tumor cells and inhibit the activity of proteins involved in cancer development. It acts as a potent inhibitor of kinase inhibitors and has demonstrated efficacy against various types of human cancers. Its unique molecular structure makes it an attractive candidate for further development as a potential therapeutic agent for cancer treatment.</p>

<p>Please enquire for more information about Chlorpromazine N-oxide maleic acid salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Haloxyfop-d4 is an analog of the herbicide Haloxyfop that has been shown to have anticancer properties. It works by inhibiting kinases, which are enzymes that play a key role in cell division and growth. This inhibition leads to apoptosis, or programmed cell death, in cancer cells. Haloxyfop-d4 has been found to be effective against a variety of human cancer cell lines, including those resistant to other anticancer drugs. In addition, it has been shown to inhibit the growth of tumors in animal models. This drug is metabolized in the liver and excreted in urine. It is not known to interact with other drugs such as rifampicin or protein kinase inhibitors.</p>

<p>Please enquire for more information about (3,5-Dimethyl-2-hexeno)-4-hydroxyphenone including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Descarboxy treprostinil is a synthetic drug product that is used as a research and development impurity standard. It has a purity of 98% or greater, and its CAS number is 101692-01-7. Descarboxy treprostinil is also used in the synthesis of related drugs, such as treprostinil sodium. This compound can be used to study drug metabolism, as well as for analysis purposes.</p>

<p>5-Desbromo, 5-chloro brimonidine is a drug product that is used as an analytical standard. It has been shown to be metabolized by CYP3A4 and CYP2D6 enzymes.</p>

<p>IPR-803 is a potent anticancer drug that belongs to the class of kinase inhibitors. It has been shown to induce apoptosis in human and Chinese hamster cancer cells by inhibiting the activity of proteins involved in cell growth and division. IPR-803 is derived from ranitidine, a medicinal compound used to treat ulcers and acid reflux. It has been found to be effective against various types of tumors and has shown promising results in clinical trials. This drug is excreted through urine and has low toxicity levels, making it a promising candidate for future cancer treatments.</p>

<p>Sm21 is a 5-HT1A receptor antagonist that can be used to treat symptoms of Parkinson's disease. It binds to the 5-HT1A receptor and prevents the release of proinflammatory cytokines, such as tumor necrosis factor-α (TNF-α). Sm21 has also been shown to have antinociceptive effects in animals by acting as a 5-HT1A agonist. This drug can also be used for treatment of neuropathic pain because it inhibits the release of serotonin from nerve endings. The drug may exacerbate dyskinesia and cause neuropathic pain when it is used with dopamine antagonists.</p>

<p>Please enquire for more information about N,N-Dimethylmethanamine vonoprazan including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Dimethrimol is a medicinal compound that has shown potential as an anticancer agent. It is an analog of inhibitors found in Chinese urine that have been used for their apoptotic effects on cancer cells. Dimethrimol has been shown to inhibit kinases, which are enzymes involved in cell signaling and proliferation. This inhibition leads to apoptosis, or programmed cell death, in human cancer cells. Dimethrimol is a promising inhibitor of tumor kinase activity and may be useful in the development of new anticancer therapies. Its protein kinase inhibitory activity makes it a valuable tool for studying the molecular mechanisms underlying cancer cell growth and survival.</p>

<p>Please enquire for more information about 2,7-Dichloro-9-[(4-chlorophenyl)methylene]-9H-fluorene including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>base ethylated deoxy-guanosine nucleoside</p>

<p>Fluphenazine decanoate EP impurity G is a metabolite of fluphenazine, which is an antipsychotic drug. Fluphenazine decanoate EP impurity G is a white powder that has been found to be a potent inhibitor of the enzyme cytochrome P450. It is used as an analytical standard and in pharmacology research.</p>

<p>2-[2-[2-(5-Bromo-2-methoxyphenyl)ethyl]-3-fluorophenyl]-4,5-dihydro-2-1H-imidazole hydrochloride (NCTC#629) is a synthetic drug product with CAS No. 1706524-94-8. It has been synthesized in our lab and is available for purchase at very competitive prices. This compound is metabolized in the liver through oxidation of the phenolic hydroxyl group to form 2-(3,4,5-trimethoxybenzyl)-3,4,5,6 tetrahydro 1H imidazole hydrochloride (NCTC#630). The chemical name of this product is 2-[2-[2-(5-bromo-2Methoxyphenyl)ethyl]-3fluorophenyl]-4,5 dihydro 2H Im</p>

<p>Cis-phenothrin is a carbamate insecticide that is used in agriculture, public health, and veterinary medicine. It has been shown to have a high degree of toxicity to mosquitoes and other pests. Cis-phenothrin acts as an acetylcholinesterase inhibitor, preventing the breakdown of acetylcholine by enzymes in the central nervous system. This allows acetylcholine levels to build up and produce toxic effects on insects such as paralysis or death. Cis-phenothrin has also been shown to be toxic to bacteria in vitro studies. It inhibits bacterial growth by binding to fatty acids and fatty acid synthases, which are essential for bacterial cell wall integrity. The inhibition of this enzyme leads to increased membrane permeability and cell lysis.</p>

<p>(4-Chlorophenyl)[4-(1-methylethoxy)phenyl]methanone is a drug product that is Custom synthesized to meet the requirements of pharmacopoeia, analytical, and drug development. It has been studied for its metabolism and toxicity profile in animals. This compound is a metabolite of chlorpheniramine, which is used as an antihistamine. Metabolites of this compound have also been identified in humans. The CAS Registry Number for this compound is 154356-96-4.</p>

<p>Bensulide is a potent inhibitor of kinases, which are enzymes that regulate various cellular processes. It has been shown to have anticancer properties by inducing apoptosis in cancer cells. Bensulide is a Chinese medicinal herb that has been used for centuries as a traditional medicine. It is an analog of protein kinase inhibitors and can be used as an inhibitor of tumor growth. Bensulide has also been found in human urine and may have potential as a diagnostic marker for cancer. Its mechanism of action involves the inhibition of protein kinases, which are involved in cell signaling pathways that regulate cell growth and division. Overall, Bensulide shows great promise as an anticancer agent with potent inhibitory effects on cancer cells.</p>

<p>Please enquire for more information about 1-(2-Chloro-1,2-diphenylethenyl)-4-(2-chloroethoxy)benzene including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Homopravastatin lactone di-(tert-butyldimethylsilyl) ether including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Oxodesmosine is an analog of a protein found in Chinese urine that has shown promise as an anticancer agent. It works by inhibiting kinases, which are enzymes that play a key role in cancer cell growth and survival. Oxodesmosine has been shown to induce apoptosis, or programmed cell death, in tumor cells both in vitro and in vivo. This compound may be useful as a therapeutic agent for the treatment of various types of cancer in humans. Additionally, Oxodesmosine has been studied for its potential synergistic effects with other kinase inhibitors such as mirtazapine. Overall, Oxodesmosine represents a promising new avenue for the development of novel anticancer therapies.</p>

<p>Rotigotine is a drug that belongs to the group of pharmaceutical formulations. It is an unlabeled drug that has been shown to be effective in the treatment of depression. Rotigotine may be administered through a transdermal patch or by iontophoresis, which is a technique used to administer drugs through the skin. The mechanism of action is not known, but it may involve the inhibition of monoamine reuptake and/or alteration of intracellular levels of catecholamines. Rotigotine sulfate has a high affinity for dopamine receptors and increases plasma concentrations of dopamine by inhibiting its reuptake into presynaptic neurons. This leads to increased concentrations of dopamine in synaptic clefts and an increase in postsynaptic receptor binding.</p>

<p>Alpha-[4-(2-dimethylaminoethoxy)phenyl]stilbene (DS) is a synthetic, analytical standard that is used as an impurity in the manufacture of pharmaceutical products. DS is also sold as a reference material for HPLC and GC/MS analysis.</p>

AG-024322 is an analog of a Chinese medicinal herb that has been found to have potent anticancer properties. It works by inhibiting cyclin-dependent kinases, which are enzymes that regulate the cell cycle and play a crucial role in cancer cell growth. AG-024322 has been shown to induce apoptosis, or programmed cell death, in cancer cells. This inhibitor of protein kinase has also demonstrated efficacy against various types of tumors in human studies. AG-024322 is one of several promising inhibitors of this class currently being developed as potential cancer treatments.

<p>2-(Sulfoacetamido) dimoxystrobin acetic acid disodium is a drug product that is an impurity of the API 2,5-dimethoxy-4-hydroxyphenylacetic acid. The CAS number for this impurity is 1196157-87-5. It is an analytical standard that is used in Metabolism studies and Natural products research. This compound is a Synthetic and Custom synthesis. It has been shown to be effective against drug development and research and development, as well as niche markets. This compound also has pharmacopoeia standards, which are high purity levels.</p>

<p>Please enquire for more information about FOS-MEA-10 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Apixaban rc G including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about (R)-2,2-Diphenyl-2-(pyrrolidin-3-yl)acetonitrile hydrobromide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>SW076956 is a potent inhibitor that targets cancer cells. This medicinal compound has been found to induce apoptosis and inhibit the growth of cancerous cells in Chinese hamster ovary (CHO) cells. SW076956 is an analog of a protein kinase inhibitor and belongs to the class of anticancer agents. This inhibitor selectively targets kinases, which are enzymes involved in cell signaling pathways that regulate cell growth and division. SW076956 has been shown to be effective against human tumor cells and may have potential therapeutic applications in cancer treatment. The compound has also been detected in urine samples, suggesting its potential as a diagnostic tool for cancer detection.</p>

<p>4-Oxo valsartan benzyl ester is a drug product that is used for research and development purposes. It is synthesized by the reaction of 4-hydroxy valsartan with benzyl bromide in the presence of a base. 4-Oxo valsartan benzyl ester has been studied for its metabolism, and it is also an impurity standard for HPLC analysis. The purity of this compound is &gt;98% and it has CAS number 188240-32-6.</p>

<p>(RS)-N-[(1-Ethylpyrrolidin-2-yl)methyl]-2-hydroxy-5-sulphamoylbenzamide is a white to off-white crystalline powder. It is soluble in methanol and ethanol, but insoluble in water. It has an assay of &gt;98% (HPLC), and a purity of &gt;99% (HPLC). This compound is used as an analytical standard for the determination of impurities in other compounds. It is also used as a pharmacopoeia standard for the determination of metabolites in pharmaceutical preparations. This compound can be synthesized from either natural or synthetic sources.</p>

<p>o-Desisopropyl-o-ethyl cefpodoxime proxetil is a drug product that is used in the treatment of infections caused by bacteria. It is a synthetic, high purity, and natural metabolite that has been developed for the treatment of bacterial infections. This drug product has been shown to have an analytical purity of &gt;99.5% and a pharmacopoeia purity of &gt;99%. o-Desisopropyl-o-ethyl cefpodoxime proxetil is also a metabolite that was synthesized to be used as an impurity standard for HPLC analysis.</p>

<p>Deiodo amiodarone is a noncompetitive inhibitor that binds to the active site of the enzyme and blocks the binding of substrate, thereby inhibiting the synthesis of catecholamines. Deiodo amiodarone has been shown to inhibit the oxidation of benzofuran derivatives in rat liver microsomes, human liver tissue samples, and chromatographic conditions. The inhibition constant for deiodo amiodarone was determined by liquid chromatography with a homogenizing technique.</p>

<p>Enalaprilat tert-butyl ester is a synthetic compound and impurity standard used in the synthesis of drug product. Enalaprilat tert-butyl ester is also a metabolite of enalapril, an angiotensin-converting enzyme (ACE) inhibitor used in the treatment of hypertension, congestive heart failure, and diabetic nephropathy. Enalaprilat tert-butyl ester has been shown to have pharmacological effects similar to those of enalapril.</p>

<p>6Beta-Hydroxy-17beta-estradiol 17-valerate is a drug product that has been synthesized for research and development. It is an impurity standard of 6β-hydroxyestrone, which is a metabolite of 17β-estradiol. 6β-Hydroxy-17β-estradiol 17-valerate is used as a research and development chemical in the field of drug metabolism studies. The compound has been shown to have niche applications in the pharmacopoeia.</p>

<p>Monobenzyl phthalate (MBP) is a metabolite of di-n-butyl phthalate (DBP), which is a chemical that is used as plasticizer. MBP is the major metabolite of DBP and has been detected in human urine. Monobenzyl phthalate β-D-glucuronide (MBPG) is an impurity found in certain drug products, including those that are marketed for the treatment of diabetes mellitus. The compound has been shown to inhibit protein synthesis and induce apoptosis in cells.</p>

<p>This is a white crystalline compound that has been shown to be effective against glutamic acid-sensitive L-amino acid decarboxylase. It is used as an intermediate in the synthesis of other pharmaceuticals.</p>

<p>5-Desthiopropyl-5-hydroxy-ticagrelor is a synthetic and new chemical entity, which is a prodrug. It is the active metabolite of ticagrelor, an antiplatelet drug used to prevent blood clots. Ticagrelor inhibits platelet aggregation by inhibiting the activity of P2Y12 receptor on the platelet surface. 5-Desthiopropyl-5-hydroxy-ticagrelor has an analytical purity of &gt;97% and a pharmacopoeia grade purity of &gt;99%. The drug product is custom synthesis and high purity, with a molecular weight of 247.9 Da. The impurity standard for this drug product is 5% (w/w) for 5-(3-(2-(3-(3-(dimethylamino)propoxy)propoxy)-pyrrolidinium bromide), also known as 3DAP; 0.1% (w</p>

<p>N-Ethoxycarbonyl dabigatran ethyl ester is a synthetic compound that is an impurity in the drug product, Dabigatran etexilate (CAS No. 1416446-40-6) which is used for the treatment and prevention of thromboembolic events. The compound was synthesized by reacting N-ethoxycarbonyl-dabigatran with ethyl acetate in the presence of a base. It has been shown to be stable when stored at 4°C for one year and does not degrade when heated at 37°C for four hours. This impurity has been characterized and its purity confirmed by HPLC analysis.</p>

<p>Cefpodoxime proxetil impurity D is a cephalosporin antibiotic that is an oral prodrug. It is used to treat infections of the mouth, throat, skin, and respiratory tract caused by gram-positive bacteria such as Streptococcus pyogenes (group A), Streptococcus pneumoniae (group B), or Staphylococcus aureus. Cefpodoxime proxetil impurity D can be converted into the active form cefpodoxime in the body. The oral absorption of this drug has been found to be rapid and complete in humans with streptococcal pharyngitis. This drug has been shown to have antibacterial efficacy against penicillin-resistant strains of group A streptococci and Staphylococcus aureus.</p>

<p>1-[[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]thio]-1H-benzi midazole is a high purity analytical standard that is used to calibrate HPLC. It is found as an impurity in the drug product and as a metabolite. 1-[(3-Methyl-4-(2,2,2 -trifluoroethoxy) - 2 - pyridinyl) methyl] - 2 - [[[3 - methyl (4 ( 2 , 2 , 2 - trifluoroethoxy) - 2 pyridinyl) methyl] thio] - 1 H benzimidazole is the IUPAC name for this compound. This chemical has been synthesized</p>

<p>(3S,5R)-Atorvastatin calcium is an analytical standard for the drug atorvastatin. It has a purity of 99.9% and is manufactured in accordance with the requirements of the pharmacopoeia. The product is available as a white crystalline powder and is soluble in water, acetone, and ethanol. (3S,5R)-Atorvastatin calcium has been used in drug development and as an impurity standard for HPLC analysis. It also serves as a metabolite to characterize the production process of atorvastatin.</p>

<p>Simotinib is a kinase inhibitor that has shown promising results in the treatment of various types of cancer. It targets specific proteins that are involved in the growth and survival of tumor cells, leading to apoptosis (cell death) and inhibition of cancer cell proliferation. This medicinal compound is an analog of cyclin-dependent kinases inhibitors and has been extensively studied in Chinese patients with lung cancer. Simotinib works by blocking the activity of certain enzymes that promote tumor growth, making it an effective anticancer agent. It has also been found to have potential therapeutic applications in other types of cancer, including breast and prostate cancer. Overall, Simotinib shows great promise as a targeted therapy for cancer treatment.</p>

<p>Please enquire for more information about Diosmin impurity 8 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Amlodipine diethyl ester is a synthetic drug that belongs to the group of calcium channel blockers. It is used for the treatment of high blood pressure, angina, and other cardiovascular diseases. Amlodipine diethyl ester is metabolized by hydrolysis to amlodipine, which has been shown to have an anti-inflammatory effect. The pharmacopoeia grade of amlodipine diethyl ester is a high purity drug product with a purity level of 98%. The CAS No. 140171-65-9 is a drug product that can be custom synthesized for research and development purposes or for use in the manufacture of pharmaceuticals.</p>

<p>3-(1-Hydroxybutyl)-1(3H)-isobenzofuranone is a medicinal compound that has been identified as an inhibitor of protein kinases. It has shown promising results as an anticancer agent, with studies indicating its ability to induce apoptosis in cancer cells. This compound has been found to be particularly effective against Chinese hamster ovary cells and human tumor cell lines. Its analogs have also been developed for use in cancer treatment, demonstrating potent antitumor activity by inhibiting the cell cycle and inducing apoptosis. The potential of 3-(1-Hydroxybutyl)-1(3H)-isobenzofuranone and its analogs as novel kinase inhibitors make them promising candidates for future cancer therapies.</p>

<p>Xanthene-d2 is an analog of xanthene that has been labeled with deuterium. It is a potent inhibitor of kinases, specifically cyclin-dependent kinases (CDKs), which play a crucial role in regulating the cell cycle and are often overexpressed in cancer cells. Xanthene-d2 has been shown to inhibit the proliferation of various human cancer cell lines, including Chinese hamster ovary cells and human colon carcinoma cells. This compound induces apoptosis in cancer cells by inhibiting CDK activity and disrupting protein synthesis. Xanthene-d2 is also used as a tool for studying kinase inhibitors and their effects on tumor growth. Its use in urine samples can help identify potential biomarkers for anticancer therapy.</p>

<p>Nicergoline EP Impurity B is a metabolite of nicergoline, a drug product. It has been synthesized for use as an impurity standard for analytical and pharmacopoeia purposes. Nicergoline EP Impurity B is not found in nature and has been shown to be metabolically stable in vitro. It can be used as a reference substance for the determination of nicergoline concentrations in human plasma samples.</p>

<p>Please enquire for more information about Rel-M-nitro-threo-chloramphenicol including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>2,2'-Bisnalmefene is a short-acting opioid antagonist that has been used for the treatment of alcohol dependence. It is effective in reducing alcohol intake and craving and it may be used to help maintain abstinence from alcohol. 2,2'-Bisnalmefene is an injectable drug that can be administered intravenously or intramuscularly. The drug should not be injected into a vein or artery because this will cause serious adverse effects. The most common adverse effect of 2,2'-bisnalmefen is respiratory depression followed by nausea and vomiting.</p>

<p>5-Ethyl-10-methoxy-5H-dibenz[b,f]azepine is a synthetic compound that is used as an impurity standard in the synthesis of drugs. It also has been used in drug development and analysis. 5-Ethyl-10-methoxy-5H-dibenz[b,f]azepine is metabolized by CYP2D6 to form 5-(1′,3′,4′,5′) -trihydroxy dibenzo[b,f][1,4]diazepin. This metabolite can be quantified using HPLC to determine the metabolic pathway of the drug product.</p>

<p>Please enquire for more information about Carvedilol tetra(alkylpyrocatechol) impurity including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Imidafenacin metabolite M4 is a synthetic impurity of imidafenacin. It is an API impurity as it is produced during the synthesis of this drug. Imidafenacin metabolite M4 has been shown to be present in high purity and is used as a pharmacopoeia standard. The compound has been studied for its metabolism, which includes studies on its ability to inhibit cytochrome P450 enzymes and other drug-metabolizing enzymes, as well as its potential to cause drug interactions.</p>

<p>N,N'-Bis[2-(3,4-dimethoxyphenyl)ethyl]-N,N'-dimethyl-1,3-propanediamine dihydrochloride is a synthetic compound that is metabolized to the natural product naphthol AS. It is an impurity in the drug product and can also be used as an analytical reference standard.</p>

<p>(1R,3S)-1-(1,3-Benzodioxol-5-yl)-2-(2-chloroacetyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic acid methyl ester is a drug product that has not yet been approved for use in humans. It is a synthetic compound and its structure is similar to the 1H indole derivative. It is metabolized in both rats and humans by oxidation of the methyl ester side chain. Metabolites have been identified in urine and feces following administration of radiolabeled (1R,3S)-1-(1,3-benzodioxol-5-yl)-2-(2 chloroacetyl)-2,3,4,9 tetrahydro 1H pyrido[3,4 b]indole 3 carboxylic</p>

<p>1,3-Dihydro-6-methylfuro[3,4-c]pyridin-7-ol is a compound that contains impurities such as fatty acids and uridine. It has been found to be an inhibitor of α-mangostin adduct formation with fatty acids. Additionally, it has been shown to inhibit the activity of GSK-3β, an enzyme involved in various cellular processes. This compound also exhibits inhibitory effects on monascus and safranal, two enzymes involved in the production of certain compounds. Furthermore, it has been found to inhibit calpain, an enzyme responsible for protein degradation. The compound can be used in various research applications involving electrode modification and polylysine immobilization. It may also have potential interactions with other drugs such as cefdinir.</p>

<p>1'-Epi-Gemcitabine 3',5'-dibenzoate is an analytical standard that is used in the drug development process. It is also a high purity, API impurity, HPLC standard, and drug product. 1'-Epi-Gemcitabine 3',5'-dibenzoate is an impurity of Gemcitabine, which is an anticancer drug. The impurity can be found in the methanolic fraction of the extract and it's an epimer of Gemcitabine. The pharmacopoeia for this compound are USP and EP. Custom synthesis and natural or synthetic are possible for this compound.</p>

<p>Cefazedone Impurity 12 is a drug product that has been custom synthesized for research and development purposes. The impurity has been shown to have a high purity level, with a CAS number of 184696-69-3. Cefazedone Impurity 12 is an analytical standard and metabolite of Cefazedone. It is also used as a natural drug development standard, which can be used for pharmacopoeia studies or as a metabolite in niche research. This impurity can be synthesized in the laboratory and can be used as an impurity standard for HPLC.</p>

<p>Etoricoxib impurity 5 is an impurity of etoricoxib. Etoricoxib is a nonsteroidal anti-inflammatory drug (NSAID) that belongs to the class of selective COX-2 inhibitors. It inhibits the production of prostaglandins and has been shown to reduce inflammation, swelling, and pain in animal studies. Etoricoxib impurity 5 is an impurity standard for HPLC analysis. This compound has not been evaluated by the FDA or other regulatory agencies.</p>

<p>7-Methoxy-N-[2-(7-methoxy-1-naphthalenyl)ethyl]-1-naphthaleneethanamine is a drug product that is a synthetic compound. It has the following analytical data:</p>

<p>Fluticasone furoate EP impurity E is an analytical reference standard for pharmacopoeia and research. It is a synthetic fluticasone furoate EP impurity that has been custom synthesized for use as a high-purity, HPLC-grade standard. Fluticasone furoate EP impurity E is characterized by its natural origin and purity, making it appropriate for use in drug development and research. The CAS number for this product is 398454-97-2.</p>

<p>Labetalol EP impurity D is a metabolite of labetalol that is used as an impurity standard for HPLC. This impurity has been identified in the drug product and also in the drug development process. Labetalol EP impurity D is one of many metabolites that can be formed by cytochrome P450 enzymes. Labetalol EP impurity D is a natural metabolite of labetalol, which can be found in the urine of humans and other mammals. It is also present in various plants and fungi, including mushrooms, lichens, yeast, and barley. Synthetic labetalol EP impurity D can also be produced by various chemical reactions.</p>