APIs per la ricerca e le impurità

<p>1-[5-(Hydroxymethyl)-2-furyl]-2-methyl-1,2,3,4-tetrahydroisochinolin-4,6-diol is an analytical standard in the form of a white solid. It is a synthetic compound that has not been found in nature and does not exist as a natural product. It is used to provide a calibration or quality control for HPLC testing. The material is also used for drug development research and development in the pharmaceutical industry.<br>1-[5-(Hydroxymethyl)-2-furyl]-2-methyl-1,2,3,4-tetrahydroisochinolin-4,6-diol (CAS No. 1312706-19) is an analytical standard in the form of a white solid. It is a synthetic compound that has not been found in nature and does not exist as a natural product. It is used to provide</p>

<p>Benzo[b]thien-2-yl ketone (zileuton impurity) is a metabolite of the drug zileuton, which is used to treat asthma. Benzo[b]thien-2-yl ketone is formed by the oxidation of benzo[b]thiophene in the presence of cytochrome P450 enzyme system. It has been found to have anti-inflammatory properties and may be useful for treating asthma. This product is available as an analytical standard for HPLC, or as a custom synthesis for research and development.</p>

<p>4',4'''-[(4'-Methyl-2'-propyl[2,6'-bi-1H-benzimidazole]-1,1'-diyl)bis(methylene)]bis[1,1'-biphenyl]-2-carboxylic acid is an analytical reagent that is used in research and development as a drug product impurity standard. This compound has been shown to be metabolized by cytochrome P450 1A1 and 2C8 to form 4-hydroxybenzoic acid and 4,4''-[(4'-methyl-2' propyl-[2,6']bi-1H-benzimidazol-1,1' diyl)bis(methylene)]bis[3-(4-hydroxyphenyl)-propionic acid], respectively. 4',4''-[(4'-Methyl-2' propyl-[2,6']bi-1</p>

<p>Please enquire for more information about (3S,4S,3’S)-Ezetimibe including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 13-Cis acitretin o-β-D-glucuronide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>2-O-[4-[[(2-Carboxyethyl)amino]carbonyl]phenyl] balsalazide is a drug product that has been custom synthesized and purified to high purity. It is an analytical standard for metabolism studies. This compound is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. 2-O-[4-[[(2-Carboxyethyl)amino]carbonyl]phenyl] balsalazide is also used as a pharmacopoeia impurity standard and as a research and development HPLC standard.</p>

<p>2-[(4-Methoxy-3-methyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole is a synthetic, impurity standard that is used in the synthesis of drug products. It has been shown to inhibit the metabolism of drugs and may be used as a marker for drug metabolism. This compound may also be used as a marker in analytical studies to assess the purity of a drug product. 2-[(4-Methoxy-3-methyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole has not been evaluated for safety or efficacy.</p>

<p>Chlorhexidine diacetate EP Impurity O is an analytical reference material that is used as a pharmaceutical impurity. It is a metabolite of chlorhexidine diacetate and has been shown to be present in the urine of patients who are taking chlorhexidine diacetate. Chlorhexidine diacetate EP Impurity O can be used for identification and quantification in HPLC analysis.</p>

<p>Diethyl 2-propylimidazole-4,5-dicarboxylate is a synthesized intermediate that can be used in the synthesis of other organic compounds. It is a diethyl ester of tartaric acid and an intermediate in the preparation of other organic compounds. The diethyl ester is made by nitrating diethyl to give diethyl nitrite, which is then reacted with tartaric acid to form the desired product. Diethyl 2-propylimidazole-4,5-dicarboxylate has been shown to be toxic, but it has not been shown to have any carcinogenic effects.</p>

<p>Carmoxirole hydrochloride is a hypoglycemic agent that is used in the treatment of type II diabetes. It is an analog of pergolide mesylate, which is a dopamine receptor agonist and has been shown to cause carcinogenesis in laboratory animals. Carmoxirole hydrochloride is synthesized from the reaction of 3-hydroxy-2-quinuclidinyl benzilate with chloroacetaldehyde, followed by hydrolysis of the ester linkages with hydrochloric acid. It has a particle size of less than 10 μm and exhibits high lipophilicity as it passes through cell membranes and into the intracellular fluid. The drug acts on all types of receptors, including alpha 1-, alpha 2-, beta 1-, beta 2-, and dopaminergic receptors.</p>

<p>Ezetimibe fluoro isomer is a drug product that is used to research and develop new drugs. It has a natural origin, and is an impurity standard for analytical purposes. Ezetimibe fluoro isomer can also be synthesized in the laboratory. This product can be metabolized by the body into its active form, ezetimibe, which inhibits cholesterol absorption in the gut by inhibiting intestinal ileal NPC1L1 protein. The pharmacopoeia recommends a purity of 98%, but this product contains 99% purity.</p>

<p>4-Methyl-2-[3-[(1-methylethyl)amino]-1-phenylpropyl]phenol is a synthetic impurity standard that is used in the synthesis of drug products. This compound is also known as 4-methyl-2-[3-[(1-methylethyl)amino]-1-phenylpropyl]phenol and has a CAS number of 480432-14-2. It is used to verify the purity of drugs and drug products. 4MMPP can be found in pharmacopoeia, drug development, and metabolite studies. This compound is a research and development product for niche markets. 4MMPP can be obtained through custom synthesis or by synthesis.</p>

<p>Loratadine is an antihistamine drug and its metabolite, loratadine epoxide, can be detected in the blood and urine of patients. Loratadine epoxide can be isolated from high-performance liquid chromatography (HPLC) with a spectrometer. The experimental method for the isolation of loratadine epoxide is to add diazomethane to a solution of loratadine in benzene. This experiment yielded a n-oxide that reacts with oxygen to form an aliphatic compound with a shift on the mass spectrum. This n-oxide has been found as an analyte in urine samples.</p>

<p>(S)-3-((R)-5-Oxopyrrolidine-2-carbonyl)thiazolidine-4-carboxylic acid is a drug product of the drug development industry. It is a metabolite of 3-(1,2,4-triazol-1-ylmethyl)thiazolidine-4-carboxylic acid and has been used as an analytical standard for HPLC methods. The compound has been shown to be naturally occurring in humans. (S)-3-(1,2,4-Triazol-1ylmethyl)thiazolidine 4 carboxylic acid is also used as the impurity standard for the API 3-(1,2,4 triazol 1ylmethyl)thiazolidine 4 carboxylic acid.</p>

<p>(3R,5R)-Pitavastatin Calcium Salt is a drug product that is used in the development of pharmaceuticals. It is a synthetic compound with an impurity standard and a metabolite impurity. The CAS number for this product is 254452-96-5. (3R,5R)-Pitavastatin Calcium Salt has been shown to be metabolized by CYP2C9 and CYP2C8 enzymes, which may result in a decrease in potency or activity. This product also has been shown to have anti-inflammatory properties and inhibit the production of inflammatory mediators such as prostaglandins and leukotrienes. (3R,5R)-Pitavastatin Calcium Salt was prepared by solid phase synthesis using a fluorous biphasic approach.</p>

<p>(2S,4S)-tert-Butyl 2-(5-(2-((2S,5S)-1-((S)-2-((methoxycarbonyl)amino)-3-methylbutanoyl)-5-methylpyrrolidin-2-yl)-1,11-dihydroisochro meno[4',3':6,7]naphtho[1,2-d]imidazol-9-yl)-1H-imidazol-2-yl)-4-(methoxymethyl)pyrrolidine-1-carboxylate is a drug product that has been synthesized and is being developed for the treatment of cancer. (2S,4S)-tert–Butyl 2-(5-(2-[(2R,5R)-1-[(R) -2-[(methoxycarbonyl)amino]-</p>

<p>Abiraterone dimer impurity is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs. It is also a metabolite of abiraterone and has been detected in the urine of patients receiving the drug. Abiraterone dimer impurity is found in trace amounts in abiraterone acetate but its pharmacological significance is not known. This impurity has been detected in the urine of patients receiving abiraterone acetate therapy.</p>

<p>Alpha-Desmethyl anastrozole is a synthetic chemical that has been used as an impurity standard for the drug product, Anastrozole (Arimidex). This compound is metabolized in humans and is a metabolite of Arimidex. Alpha-Desmethyl anastrozole exhibits high purity and can be synthesized using custom synthesis. The CAS number for this compound is 1215780-15-6.</p>

<p>Lysolecithin is an analog of the phospholipid lecithin that has been shown to have anticancer properties. It works by inhibiting kinases, which are enzymes that play a crucial role in cell signaling and regulation. Lysolecithin promotes apoptosis, or programmed cell death, in cancer cells, making it a promising medicinal agent for the treatment of tumors. Studies have also shown that lysolecithin can inhibit protein kinase activity in human urine and inhibit the growth of cancer cells in Chinese hamsters. This compound may prove to be a valuable tool in the development of kinase inhibitors for cancer therapy.</p>

<p>Tenofovir disoproxil fumarate is a prodrug of tenofovir that is used as a clinical medication to treat HIV. Tenofovir works by inhibiting reverse transcriptase, an enzyme required for the production of viral DNA. The flow rate of this drug is high and it has a sensitivity of less than 1 ng/mL. Tenofovir disoproxil fumarate contains impurities such as methoxy, which can affect the chiral purity and sensitivity of the drug. It also contains tenofovir, which is used as an intermediate in its synthesis. This drug can be detected using chromatographic methods, which use n-hexane and a wavelength below 220 nm for liquid chromatography analysis.</p>

<p>Desgadolinium gadoteridol is a contrast agent that is used in magnetic resonance imaging (MRI). It is a gadolinium-based contrast agent that contains an ester linkage. The chelate complex of gadolinium with desgadolinium has been shown to have high water permeability and target tissue affinity, as well as low toxicity. Desgadolinium gadoteridol is used to diagnose inflammatory bowel diseases by determining the thickness of the bowel wall. This agent may also be used to evaluate blood pressure and diagnose hemorrhoids or colorectal polyps.</p>

<p>N-Formyl-L-leucine (1R)-1-[[(2R,3R)-3-Hexyl-4-oxo-2-oxetanyl]methyl]dodecyl ester is an impurity standard for HPLC. It is a synthetic compound that has been custom synthesized to meet the requirements of a pharmacopoeia. This product is offered in a high purity and can be used for drug development and research and development.</p>

<p>Duloxetine is a drug product that belongs to the class of drugs known as selective serotonin and norepinephrine reuptake inhibitors. Duloxetine is a metabolite of duloxetine phenyl carbamate, which is an impurity standard for HPLC analysis. Duloxetine has been shown to inhibit the metabolism of serotonin and norepinephrine in the brain, leading to increased amounts of these neurotransmitters. This medication has been studied in niche populations such as those with depression and diabetic neuropathy. Duloxetine also has high purity standards, meeting the requirements of pharmacopoeia.</p>

<p>Deterenol acetate is a drug product that is used as an analytical standard. It has been shown to be a natural metabolite of the synthetic drug deterenoic acid, which is an impurity in API preparations of the drug. Deterenol acetate has been shown to have anti-inflammatory effects and may be useful for treating cardiovascular disease, cancer, and arthritis. Deterenol acetate has also been shown to have potential as a treatment for high blood pressure.</p>

<p>Ephedrine Hydrochloride EP Impurity A is a product of the biotransformations of pseudoephedrine. It has been shown that this impurity can be formed in enzymatic reactions where pseudoephedrine is acted upon by β-unsaturated ketones or by filamentous fungi. Ephedrine Hydrochloride EP Impurity A is a chiral compound, which means that it has two different forms that are non-superimposable mirror images of each other. The enantiomers (left and right) are the individual molecules that make up the racemic mixture. In some cases, ephedrine hydrochloride ep impurity a may be present as a result of a reaction between pseudoephedrine and an enzyme preparation containing β-unsaturated ketones, such as acetone peroxide or benzoyl peroxide. This impurity has been shown to inhibit candida glabrata and to have kinetic properties similar to that of ephed</p>

<p>The major (R,S)-equol-d4 is a metabolite of the soy isoflavone daidzein. It is used as an impurity standard for HPLC analysis and as a research and development substance. The pharmacopoeia defines it as a drug product, while the FDA considers it to be an analytical standard. It has been shown to have anti-inflammatory properties in animal studies.</p>

<p>Cefotaxime sodium impurity C is a by-product of the synthesis of cefotaxime. It is an impurity standard for drug product, custom synthesis and research and development. The CAS number for this substance is 66403-32-5. This compound has been shown to be a metabolite in metabolism studies. Impurity standard compounds are used in analytical methods such as HPLC.</p>

<p>Ethopropazine hydrochloride is a drug that inhibits the enzyme activity of acetylcholinesterase, which is involved in the breakdown of acetylcholine. It also has inhibitory properties for other enzymes, including monoamine oxidase and phosphodiesterase. Ethopropazine hydrochloride has been used to treat infectious diseases such as tuberculosis and malaria. Biocompatible polymers are used in the preparation of this drug to produce a slow release formulation that can be administered intravenously or orally. The optimum concentration for ethopropazine hydrochloride is 10-100 μM. The fluorescence probe, 4-amino-N-(7-nitrobenzofurazan) acetic acid (ANBAA), has been used to measure concentrations of this drug in redox reactions by quenching the fluorescence signal of ANBAA at an optimal concentration of 100 μM. Group P2 axonal growth was increased with ethop</p>

<p>MKK7-COV-9 is a potent inhibitor of kinases that plays a critical role in apoptosis, also known as programmed cell death. It has been extensively studied in Chinese and human tumor cells and has been shown to be an effective anticancer agent. MKK7-COV-9 is an analog of the cyclin-dependent kinase (CDK) inhibitors and has been found to inhibit the growth of cancer cells by blocking the activity of CDKs. This protein kinase inhibitor has also been found in urine samples from cancer patients, suggesting its potential as a biomarker for cancer diagnosis and treatment. The inhibitory effect of MKK7-COV-9 on tumor cell proliferation makes it a promising candidate for developing novel anticancer drugs.</p>

<p>Aliskiren is a drug that is used for the treatment of hypertension. It is not active orally and must be given by injection or intravenously. Aliskiren is an impurity in the synthesis of aliskiren carboxylic acid, which can be found in the chemical catalogues. Aliskiren carboxylic acid is an analytical standard with high purity and can be used as an impurity standard for HPLC analysis. The CAS number for Aliskiren carboxylic acid is 173400-13-0. Aliskiren Carboxylic Acid can also serve as a metabolite or pharmacopoeia reference material, if needed.</p>

<p>Ethosuximide impurity A is a fluorinated compound that inhibits the enzyme acetylcholinesterase. It has been shown to inhibit the catalytic mechanism of acetylcholinesterase, which leads to its inhibitory effect on the enzyme. The compound does not have any structural similarity to the other known inhibitors of this enzyme. Ethosuximide impurity A has been shown to be an antimutagen and anticarcinogen in vitro, with a postulated mechanism of action that involves inhibition of a water molecule from binding to the active site.</p>

<p>N-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-formamide is an analytical standard that is used for the determination of formamide in pharmaceutical formulations. N-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-formamide is a synthetic compound and has a natural impurity which may be present at levels up to 10%. The CAS number for this compound is 911805-54-4. N-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-formamide is an impurity standard for HPLC analysis. It has been synthesized and characterized by the United States Drug Enforcement Agency (DEA). It can be used as a reference substance in pharmacopoeia standards.</p>

<p>Ulifloxacin acyl-β-D-glucuronide is an inhibitor of protein kinases that has been shown to induce apoptosis in cancer cells. This compound is a metabolite of ulifloxacin, a fluoroquinolone antibiotic used to treat urinary tract infections. Ulifloxacin acyl-β-D-glucuronide has potent anticancer activity and has been shown to inhibit the growth of tumor cells in vitro. This compound is an analog of other kinase inhibitors and has been extensively studied in Chinese hamster ovary (CHO) cells, where it was found to be effective against various types of cancer. Ulifloxacin acyl-β-D-glucuronide also possesses toxin-binding properties and may have potential as an anti-toxin agent.</p>

<p>Please enquire for more information about 4'-Bromo-2-(diethylamino)-2',6'-acetoxylidide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Δ2-Cefuroxime is a prodrug that is hydrolyzed in vivo to cefuroxime, its active form. It has a high rate of hydrolysis, which can be increased by buffers, and it is commonly used as an intravenous or intramuscular injection. Δ2-Cefuroxime has two isomeric forms: the cis-isomer and trans-isomer. The cis-isomer has a higher rate of hydrolysis than the trans-isomer, but both forms have equal antibacterial activity. In addition, Δ2-cefuroxime can be converted into erythromycin.</p>

<p>Aprepitant β-glucuronide sodium salt is a unique compound that has been shown to have potent anti-cancer properties. It works by inhibiting the cell cycle and inducing apoptosis in cancer cells. Aprepitant β-glucuronide sodium salt has been extensively studied in Chinese medicine and has shown promising results as an anticancer agent. This compound can be used to target specific proteins involved in the growth and proliferation of cancer cells, making it a highly effective treatment option for various types of tumors. Additionally, nanoparticles containing Aprepitant β-glucuronide sodium salt have been developed, which allows for targeted delivery and improved efficacy. Overall, this innovative compound holds great potential as a powerful tool in the fight against cancer.</p>

<p>9-Hydroxymethyl-10-carbamoylacridan is an active metabolite of carbamazepine. It is a potent competitive inhibitor of the enzyme acetylcholinesterase, which leads to increased levels of acetylcholine in the human brain and causes decreased seizure threshold. 9-Hydroxymethyl-10-carbamoylacridan can be found in wastewater and it has been detected in the water supply and in human serum. 9-Hydroxymethyl-10-carbamoylacridan is also present in human urine and can be detected by high performance liquid chromatography (HPLC). This compound has been shown to cause epileptic seizures in humans.</p>

<p>Dorzolamide impurity B is a drug product, HPLC standard, and Drug development Impurity standard. It is also used in Natural, Research and Development, Metabolite, and Synthetic studies. This drug product has a CAS No. of 120279-90-5. Dorzolamide impurity B is a Metabolite that is found in the urine of those who take this drug. This metabolite can be found as an analytical impurity in the API (active pharmaceutical ingredient). It is also a pharmacopoeia impurity for use in niche applications.</p>

<p>(betaR,deltaR)-2,3-Bis(4-fluorophenyl)-beta,delta-dihydroxy-5-(1-methylethyl)-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic acid hemicalcium salt is an impurity that is used in the production of a drug product. This product is metabolized to (betaR,deltaR)-2,3-bis(4-fluorophenyl)-beta,delta-dihydroxy-5-(1-methylethyl)-4-[(phenylamino)carbonyl]-1H-pyrrole 1 heptanoic acid which is used as an analytical standard for HPLC.</p>

<p>(E)-4-(((2S,4R)-1-([1,1'-Biphenyl]-4-yl)-5-ethoxy-4-methyl-5-oxopentan-2-yl)amino)-4-oxobut-2-enoic acid is an organic compound that is a metabolite of the drug product. It is a synthetic chemical compound and does not occur in nature. It has been used as an analytical standard for HPLC and LC/MS. It has also been used as an impurity standard for API's. This product is typically produced synthetically, but can be obtained through metabolism studies with niche organisms such as fungi or bacteria. It should be noted that this product is not pharmacopoeia grade and cannot be used in medical devices or drugs.br&gt;br&gt;<br>This product has been classified by the International Union of Pure and Applied Chemistry (IUPAC) as a 2-(3-(aminoc</p>

<p>10-Allyl-2-chloro-phenothiazine is a metabolite of the drug product, Clopidogrel. It is a white crystalline powder that is soluble in water and alcohol. 10-Allyl-2-chloro-phenothiazine is used as an analytical standard for HPLC and NMR studies of Clopidogrel. It also is used as an impurity standard for the determination of purity of this drug product. This chemical belongs to the group of synthetic compounds that are metabolized by humans. Studies have been conducted on its metabolism, which has led to the discovery of its metabolites and their properties. This compound has not been evaluated by any pharmacopoeia or regulatory agency and should be handled accordingly.</p>

<p>3-(Cyanomethyl)-N-methyl-1H-indole-5-methanesulfonamide is an analytical standard, used for HPLC analysis of impurities. It is also used as a reference in certain pharmacopoeia standards, such as the USP and EP. 3-(Cyanomethyl)-N-methyl-1H-indole-5-methanesulfonamide has a purity of 99% and can be found in the drug product Impurity Standard.</p>

<p>1,8,15,22-Tetraazacyclononacosane-2,9,16,23-tetrone is a potent inhibitor of kinases that have been shown to be involved in the growth and survival of cancer cells. This compound was isolated from Chinese urine and has been found to induce apoptosis in cancer cells by inhibiting kinase activity. The analogs of this compound have been developed as anticancer agents due to their ability to inhibit cyclin-dependent kinases (CDKs) that are involved in cell cycle regulation. This inhibitor has shown promising results in preclinical studies for the treatment of various types of tumors, including breast cancer and lung cancer. It is a potential candidate for further development as an anticancer drug due to its high specificity towards human kinases and low toxicity towards healthy cells.</p>

<p>4-Hydroxy-N-2-pyridinyl-2H-1,2-benzothiazine-3-carboxamide-1,1dioxide is a drug product that is used as an analytical reference material. It is a white to pale yellow powder that is soluble in water and has a molecular weight of 343.4 g/mol. The compound has been used for the development of drugs with therapeutic potential against cancer, diabetes, and other diseases. The following are some of the impurities that may be found in 4-hydroxy-N-2-pyridinyl-2H--1,2--benzothiazine--3--carboxamide--1,1dioxide: CAS No.: 65897 - 46 - 3 Molecular weight: 343.4 g/mol Melting point: Boiling point: Density: 1.7 g/cm</p>

<p>Sulofenur is an analog of capsaicin, a compound found in chili peppers, that has been shown to have anticancer properties. It works by inhibiting kinases, enzymes that play a role in cell signaling and regulation. Sulofenur has been found to induce apoptosis, or programmed cell death, in cancer cells. It is a potent inhibitor of protein kinases and has been shown to be effective against a variety of tumors. In addition, Sulofenur has been tested in Chinese hamster ovary cells and human urine samples with promising results. Its potential as an anticancer agent makes it a valuable tool for cancer research and treatment.</p>

<p>9-Desfluoro-9(11)-epoxy triamcinolone acetonide is a synthetic metabolite of the natural drug product 9-desfluoro-9(11)-epoxy triamcinolone acetonide. It is a white to yellowish crystalline powder that is soluble in acetone, ethanol, and chloroform. It has been used as an analytical standard for HPLC and GC analysis. The purity of 9-desfluoro-9(11)-epoxy triamcinolone acetonide should be greater than 98% with less than 0.1% impurities determined by NMR spectroscopy or by high performance liquid chromatography (HPLC).</p>

<p>Clomiphene is a drug that is used to treat female infertility. It binds to estrogen receptors and blocks the natural production of estrogen, which is necessary for ovulation. Clomiphene has been shown to have toxicological effects on human serum, including the induction of metabolic disorders such as hyperlipidemia and hyperglycemia. It also has an adverse effect on the matrix effect in vitro, which may be due to its ability to inhibit enzymes involved in citrate metabolism. Clomiphene has been shown to increase the risk of developing type 2 diabetes mellitus in women with pre-diabetes or gestational diabetes mellitus, although this risk was reduced by the use of metformin. Trans-clomiphene is a synthetic form of clomiphene that may have fewer side effects.</p>

<p>Quincarbate is a medicinal compound that acts as an inhibitor of kinase enzymes. Kinases play a crucial role in cellular signal transduction and are involved in the regulation of various cellular processes, including cell growth and proliferation. Quincarbate has been shown to inhibit the activity of kinases in human cancer cells, leading to anticancer effects. This compound induces apoptosis, or programmed cell death, in tumor cells and inhibits their growth. Quincarbate is also an analog of a Chinese herbal medicine used for centuries to treat cancer. This potent anticancer agent can be detected in urine after administration and has promising therapeutic potential for cancer treatment.</p>

<p>Alisporivir intermediate-1 is a drug product that is used for analytical and metabolism studies. It is a natural API impurity of Metabolism studies, CAS No. 882506-05-0, and has an Impurity standard of Synthetic. Alisporivir intermediate-1 is also an analytical standard for HPLC and pharmacopoeia standards for High purity. The impurity can be synthesized with Custom synthesis or made from Natural sources. It is a niche product that is used in Research and Development, Drug development, and other applications.</p>

<p>Please enquire for more information about 5-Deoxy-Δ5,6-8-epi-tacrolimus including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Acetamidodiphenyl ether (AEP) is a toxic environmental chemical that is used in the manufacture of plastics, rubber and pesticides. This compound has been shown to be able to cross the blood-brain barrier and accumulate in the brain, causing inflammation. AEP is also able to bind to astroglia and microglial cells in the brain, which are cells that play an important role in neuroinflammation. The accumulation of AEP in these cells leads to activation and demyelination, which are both damaging processes for neurons. Techniques such as immunofluorescence have been employed to study how AEP affects these cells at a molecular level.</p>

<p>4-Methylbenzylidene camphor-d4 is an analytical reference standard. It is used as a high purity drug development API impurity, HPLC standard, and CAS No. 1219806-41-3. 4-Methylbenzylidene camphor-d4 is also used in the manufacture of niche drug products that require Impurity standards and Metabolites.</p>

<p>Pogostol is a potent anticancer agent that has been shown to inhibit the growth of tumor cells in humans. It works by inhibiting kinase activity, which is involved in cell signaling and regulation. Pogostol is an analog of artesunate, a drug used to treat malaria, and has been found to be effective against cancer cells in vitro and in vivo. It has also been shown to enhance the anticancer effects of other drugs such as chloroquine. Pogostol induces apoptosis (programmed cell death) in cancer cells by inhibiting kinases and disrupting cellular signaling pathways. This compound has potential as a novel therapeutic agent for the treatment of cancer, and its urine levels can be used as a biomarker for its efficacy.</p>

<p>(-)-Nefopam is a medicinal compound that acts as an inhibitor of kinases, which are enzymes involved in many cellular processes. It has been shown to inhibit the growth of cancer cells by inducing apoptosis, or programmed cell death. In Chinese hamster ovary cells, (-)-Nefopam has been found to inhibit the uptake of xylose into the cell, suggesting that it may have an effect on carbohydrate metabolism. This compound has also been shown to interfere with the cell cycle and protein synthesis in human cancer cells. Overall, (-)-Nefopam shows promise as a potential therapeutic agent for cancer treatment.</p>

<p>Please enquire for more information about 4-(Diphenylmethylene)-1-methylpiperidine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Fluticasone Impurity D is a sulfoxide that is found in the drug fluticasone. It is a conjugate of fatty acid and fatty alcohol, which are esters of irritants. Fluticasone Impurity D is an experimental model for inflammatory diseases. It can be used as a pharmaceutical dosage to enhance the effects of other drugs by increasing their absorption through the skin. The effects of this drug have been tested on tissues and experimental models, but not on humans.</p>

<p>Moexipril, also known as Moexipril cyclohexyl analogue hydrochloride, is an analytical standard for HPLC and LC-MS. It is a white to off-white powder with a molecular weight of 461.84. Moexipril is soluble in ethanol and methanol, but insoluble in water. It has been shown to be metabolized into two metabolites: the major metabolite (M1) and a minor metabolite (M2). The CAS number for Moexipril is 1356019-89-0.</p>

<p>Please enquire for more information about PTGR2-IN-1 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Tymazoline hydrochloride is a medicine that belongs to the class of imidazolines. It is used to treat allergic diseases and other conditions where it is desirable to reduce the production of histamines. Tymazoline hydrochloride has been shown to inhibit histamine release from mast cells in vitro, and it is also used as an antihistamine. Tymazoline hydrochloride crystallizes from water as the dihydrate, and its diffraction patterns have been determined using synchrotron radiation. The molecule has an orthorhombic crystal structure with spacings of 0.7-0.8 nm between planes and intensities of 5-6 cm-1 in the X-ray region. Techniques such as molecular modelling and crystallography have been used to study this drug's structure and properties.</p>

<p>2,12-Dihydro-1,3-dimethyl-8-methoxy-12-thioxobenzo [4,5] pyrido [1,2-c] imidazo [1,2-a] imidazol-2-one is a metabolite of the drug 2-[2-(4,5,-dihydroimidazo[1,2a]imidazol -2(3H)-yl)ethoxy]-N-(methylsulfonyl)benzamide. It can be used as an impurity standard for the manufacture of drugs and as a research chemical.</p>

<p>N-[2-(Diphenylmethoxy)ethyl]-N,N',N'-trimethyl-ethylenediamine dimaleate is a drug product that is used as an analytical standard. It is a synthetic compound that has been shown to have anti-inflammatory properties. This product is also metabolized in the liver, and can be used to study the metabolism of drugs. CAS No. 2718-46-9, API impurity, Synthetic, Metabolism studies, niche, High purity</p>

<p>Acetamido-5-benzylthio-1,3,4-thiadiazole is an impurity that is found in the drug product acetamido-5-(2,6-dichlorobenzyl)thio-1,3,4-thiadiazole. It has been used as an analytical standard for HPLC and as a pharmacopoeia impurity standard. Acetamido-5-benzylthio-1,3,4-thiadiazole is also a metabolite of acetamido-5-(2,6 dichlorobenzyl)thio-1,3,4 thiadiazole. This compound has been detected in natural sources such as plants and animals. Acetamido-5-(2,6 dichlorobenzyl)thio 1,3,4 thiadiazole can be synthesized by reacting 2 chloroacet</p>

<p>Pravastatin diol lactone is a lipase inhibitor that prevents the hydrolysis of triglycerides in the intestines. It also inhibits the synthesis of cholesterol by inhibiting hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase. Pravastatin diol lactone has been shown to be effective in reducing serum cholesterol levels in animal models and inhibiting esterification of cholesterol by preventing the conversion of HMG-CoA to mevalonic acid, which is an important step in the synthesis of cholesterol. Pravastatin diol lactone is a polyketide that was discovered from a fungus and chemically altered to produce this drug.</p>

<p>Ornidazole-hydroxy is a drug product that is manufactured using HPLC. It is used to be the standard for Drug development, Natural, Custom synthesis, Research and Development, Metabolite, Impurity standard, analytical, API impurity and Synthetic. The metabolite of ornidazole-hydroxy is an impurity in the pharmacopoeia. Ornidazole-hydroxy has been shown to inhibit bacterial growth in vitro by inhibiting protein synthesis through inhibition of ornithine decarboxylase. Ornidazole-hydroxy also showed good activity against Clostridium difficile in animal models of infection.</p>

<p>(1-(Cyanomethyl)cyclopropyl)methyl methanesulfonate is a potent inhibitor of kinases, which are enzymes that play a critical role in tumor growth and replication. This compound has been shown to inhibit the activity of several cancer cell lines, including those resistant to methotrexate, by inducing apoptosis. It is an analog of astaxanthin, a natural antioxidant found in Chinese urine. This compound has potential as a cancer therapeutic due to its ability to selectively target cancer cells while sparing normal human cells. Additionally, (1-(Cyanomethyl)cyclopropyl)methyl methanesulfonate may be used as a kinase inhibitor in research settings to further understand the mechanisms behind cancer growth and develop new inhibitors for potential therapies.</p>

<p>Please enquire for more information about PD-166285-d4 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Di-destriazole anastrozole dimer impurity is a synthetic impurity that is created during the synthesis of anastrozole. It has been studied as a possible metabolite of the drug, but its role in metabolism is not well understood. Di-destriazole anastrozole dimer impurity is soluble in water and methanol and has a melting point of between 1°C to 2°C. The purity of this compound is typically at least 99% with a specific gravity of 1.043 g/mL.</p>

<p>Ganciclovir mono-o-propionate is an analytical reference standard for HPLC analysis. It is also a drug development intermediate, an API impurity, and a metabolite of ganciclovir. Ganciclovir mono-o-propionate is a crystalline solid with a melting point of 119°C and a molecular weight of 312.5. This compound can be found in the USP/NF (2009) as an impurity in the ganciclovir product. Ganciclovir mono-o-propionate has been used by companies to synthesize ganciclovir or other analogues for research purposes. The natural form of this compound can be found in plants such as apple leaves and grape leaves, but it can also be synthesized from chloroacetic acid and propionic acid.</p>

<p>N-Desmethyl azithromycin B is a metabolite of the macrolide antibiotic azithromycin. It is an impurity in the drug product, and is present as an analytical standard for HPLC. N-Desmethyl azithromycin B can be found in the urine of patients taking azithromycin, but at much lower concentrations than the parent drug. This impurity is not toxicologically relevant, but may interfere with some analytical methods.</p>

<p>This product is an organic compound that has a molecular formula of C6H7N3O2. It is a white solid with a melting point of 76.5 °C and an elution time of 7 minutes (range, 1-10 minutes). The detection method is based on the color change from yellow to blue in the presence of dimethylformamide (DMF). This product is used as a solvent for various chemical reactions and can be used in the synthesis of other products. 3-(Formylamino)-1H-pyrazole-4-carboxamide is used in analytical chemistry to determine substances such as pH, ionic strength, and concentration. In addition, this product can be used to quantify substances such as drugs or pharmaceuticals.</p>

<p>Pyridine-2-methanol methiodide is a drug product that is used as an HPLC standard. It is also used in the development of new drugs, natural products, and research and development. Pyridine-2-methanol methiodide has been shown to have anti-inflammatory properties in metabolism studies. This compound has a niche application as an API impurity standard for analytical purposes. The CAS number for this compound is 3313-51-7. Synthetic methods are required to produce this substance. It is a high purity chemical with pharmacopoeia applications.</p>

<p>Please enquire for more information about Evixapodlin including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Desdifluoromethoxy hydroxy pantoprazole is a synthetic compound that is used as an impurity standard for the drug product Pantoprazole. It has a purity of ≥98% and is stable under ambient conditions. Desdifluoromethoxy hydroxy pantoprazole is not active on its own, but it is a metabolite of pantoprazole. It can be used to study the metabolism of pantoprazole.</p>

<p>Moclobemide N-oxide is a metabolite of moclobemide, an antidepressant drug. It is a white to off-white crystalline powder with a molecular formula of C14H14N2O4 and a molecular weight of 237.3. Moclobemide N-oxide is used in the treatment of depression, but it has not been approved for clinical use in the United States. Moclobemide N-oxide is extensively metabolized by cytochrome P450 enzymes, which may lead to variations in its activity among patients.</p>

<p>Lincomycin impurity B is a chemical substance which is the result of the metabolism of lincomycin. It is found in the urine and feces of patients who have taken lincomycin orally. Lincomycin impurity B has been detected in various commercial formulations of lincomycin, but its concentration varies with different batches. The HPLC standard purity for lincomycin impurity B is up to 99%. Lincomycin impurity B can be used as an analytical standard for HPLC analysis and as an API impurity in drug development. It also may be used as a research metabolite or pharmacopoeia reference material.</p>

<p>Please enquire for more information about 4-Acetyl-3,4-dihydro-2H-pyrido[3,2-b]oxazine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Demethylpiperazinyl Sildenafil Sulfonic Acid is a prodrug of sildenafil, which is an organic compound. It is used in the treatment of erectile dysfunction and pulmonary arterial hypertension. This drug is metabolized by hydrolysis to form sildenafil citrate, which then acts as an inhibitor of cGMP-specific phosphodiesterase type 5 (PDE5). This enzyme regulates the intracellular levels of cyclic guanosine monophosphate (cGMP), which are needed for the relaxation of smooth muscles in the corpus cavernosum and pulmonary arteries. Demethylpiperazinyl Sildenafil Sulfonic Acid has been shown to have a good safety profile with no major adverse effects or interactions with other drugs.</p>

<p>(-)-Neoisomenthol is a drug product that is a natural product and is found in peppermint oil. It has been shown to have anti-inflammatory and analgesic properties. (-)-Neoisomenthol has been synthesized chemically, but it can also be found as a metabolite of menthol in the body. The natural form of (-)-neoisomethyl is found in plants such as peppermint or spearmint, whereas the synthetic form is used for medicinal purposes. This compound has shown to be effective against pain and inflammation when applied topically, but not orally.</p>

<p>Norchlorprothixene is a psychoactive drug with hypnotic and sedative effects. It is a kind of phenothiazine derivative that can be used as an antipsychotic drug. Norchlorprothixene has been found to be effective in the treatment of patients suffering from schizophrenia and other psychotic disorders. It is also prescribed for the treatment of anxiety, depression, insomnia, and tension. The death rate of norchlorprothixene is unknown. Norchlorprothixene has been shown to be detected in tissues at concentrations that are higher than those in plasma. The chromatographic profile of norchlorprothixene is not known but it may be possible to identify this substance by its solvents, which are non-polar solvents such as chloroform and ethers. Norchlorprothixene can be quantified by immunoassays or by polypeptide assays using electrospray ionization mass spectrom</p>

<p>Flumethasone Impurity 10 is a synthetic drug product. It is for research and development purposes only and not for use in humans. Flumethasone Impurity 10 is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. Flumethasone Impurity 10 can be used as an impurity standard for the determination of flumethasone in biological fluids.</p>

<p>D-Fuculose is a medicinal compound that has shown anticancer properties in various studies. It is a kinase inhibitor that targets specific kinases involved in cancer cell growth and survival. D-Fuculose has been found to induce apoptosis, or programmed cell death, in tumor cells and inhibit the growth of cancer cells. It has also been shown to have potential as a therapeutic agent for hepatocellular carcinoma (HCC) by reducing the expression of hepcidin, a protein associated with HCC progression. D-Fuculose can be found in Chinese herbal medicine and has been detected in urine samples from healthy individuals, indicating its potential as a natural anticancer agent.</p>

<p>K-(D-1-Nal)-fwll-NH2 is a drug product that is custom synthesized to order. It has been shown to have high purity, analytical and metabolic studies. The metabolite of K-(D-1-Nal)-fwll-NH2 is D-1-nal. This product has been shown to be used in the development of drugs for niche markets and as an impurity standard for HPLC analysis. K-(D-1-Nal)-fwll-NH2 is also a synthetic drug that belongs to the class of naphthyridines. It has a CAS number of 1394288-22-2 and an impurity standard that can be used for research and development purposes.</p>

<p>Tetramethylrhodamine cadaverine is a medicinal compound that has shown promising results in the treatment of cancer. This Chinese analog has been found to induce apoptosis, or programmed cell death, in cancer cells by inhibiting kinase activity. It also acts as an inhibitor of nalbuphine, a protein involved in tumor growth and progression. Tetramethylrhodamine cadaverine has been studied extensively for its anticancer properties and has shown efficacy against various types of human cancers. Additionally, this compound can be detected in urine samples and serves as a useful biomarker for cancer diagnosis and monitoring. With its potent properties as an anticancer agent, tetramethylrhodamine cadaverine holds great promise for the development of novel cancer therapies.</p>

<p>This is an analytical standard for the impurity N-[[2-[[[4-[[(hexyloxy)carbonyl]amino]carbonyl]phenyl]amino]-methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-2-pyridinyl-β-alanine ethyl ester. It has a purity of &gt;98% by HPLC and is available in quantities of 5g.</p>

<p>Please enquire for more information about 3,14-Dihydroxy 14β-estra-1,3,5(10)-trien-17-one including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Mono-(4-methyl-7-oxooctyl)phthalate (MMP) is a metabolite of the phthalate esters, which are synthetic chemicals used in plastics and other materials. MMP has been detected in the urine of neonates and preschool children, suggesting that it can be absorbed through skin contact. This compound is also found in wastewater, where it may cause estrogenic effects on human cells. The reaction solution of MMP with insulin-like growth factor (IGF) was studied by kinetic analysis and logistic regression to determine its binding affinity for IGF binding proteins. MMP has shown to be biodegradable under aerobic conditions.</p>

<p>Torasemide EP Impurity C is a drug product that is used as an analytical standard in the metabolism studies of torasemide. Torasemide EP Impurity C belongs to the group of metabolites, and it has been shown to have pharmacopoeia standards. Torasemide EP Impurity C can be found in natural products, but also synthesized in laboratories.</p>