APIs per la ricerca e le impurità

<p>Racemic 2-amino-2-(hydroxymethyl)propane-3-ol-1-yl (5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylate) is a synthetic drug product. It is used in research and development as an impurity standard. It is also used to synthesize drug products, which are custom synthesis and not commercially available. The racemate is a metabolite of the natural compound "Lysergic acid" and has been studied for its effects on metabolism.</p>

<p>Please enquire for more information about 2-(Methoxyimino)-3-oxo-butanoic acid ethyl ester including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>(2S, 4’R, 8’S)-α-Tocopherol is a vitamin E compound that has been shown to have various health benefits. It acts as an antioxidant and protects cells from oxidative damage. Additionally, it has been found to inhibit the growth of cancer cells by inducing apoptosis, inhibiting protein kinase C activity, and blocking the cell cycle. Studies have shown that (2S, 4’R, 8’S)-α-Tocopherol is a potent inhibitor of tumor growth in Chinese hamster ovary cells and human breast cancer cell lines. This vitamin has also been detected in urine samples of individuals who consume a diet rich in vitamin E. Overall, (2S, 4’R, 8’S)-α-Tocopherol is an important anticancer agent with promising therapeutic potential for cancer treatment.</p>

<p>6-Ethenyl-3-methyl-4-phenyl-2-pyridinecarboxylic acid methyl ester is an impurity standard for use in the drug product formulation and development of drugs. It is a synthetic, high purity, pharmacopoeia grade chemical that can be used as an analytical reference standard for HPLC. 6-Ethenyl-3-methyl-4-phenyl-2-pyridinecarboxylic acid methyl ester is a metabolite of nicotinamide and has been studied extensively by metabolism studies.</p>

<p>2-[[4-(2-Pyridylsulfamoyl)phenyl]azo]hydroxybenzene is an impurity found in sulfasalazine. It is a metabolite that is formed by the P450 system in the liver. The metabolic process of 2-[[4-(2-Pyridylsulfamoyl)phenyl]azo]hydroxybenzene has been studied in detail and has been shown to be a major contributor to the pharmacokinetic profile of sulfasalazine. This substance also exhibits antimicrobial activity and inhibits the growth of bacteria, fungi, and viruses.</p>

<p>Methyl mycophenolate impurity E is a reactive, propargylamine-containing, monosodium salt with immunosuppressive properties. It is used in the treatment of cancer by inhibiting the production of white blood cells, which are needed to fight infection. Methyl mycophenolate impurity E has shown antitumor activity and can be used for the treatment of some types of cancer. It is metabolized in vivo to methyl mycophenolate and inhibits protein synthesis by alkylating DNA.</p>

<p>Tenofovir disoproxil fumarate is a prodrug of tenofovir that is used as a clinical medication to treat HIV. Tenofovir works by inhibiting reverse transcriptase, an enzyme required for the production of viral DNA. The flow rate of this drug is high and it has a sensitivity of less than 1 ng/mL. Tenofovir disoproxil fumarate contains impurities such as methoxy, which can affect the chiral purity and sensitivity of the drug. It also contains tenofovir, which is used as an intermediate in its synthesis. This drug can be detected using chromatographic methods, which use n-hexane and a wavelength below 220 nm for liquid chromatography analysis.</p>

<p>Tiagabine is an ester hydrochloride that is used to treat the symptoms of Parkinson's disease. Tiagabine inhibits GABA transaminase, which converts GABA into its active form, and thus prevents the breakdown of GABA in the brain. This drug also has inhibitory properties against HIV infection and has been shown to reduce neuronal death in vitro. Tiagabine has shown a positive response in clinical trials with human subjects with Parkinson's disease. Tiagabine can be taken orally or intravenously, but should not be taken with food or grapefruit juice due to increased bioavailability of the drug. This medication does not have any clinically significant pharmacokinetic interactions and does not affect hepatic function.</p>

<p>5'-O-Acetyl ribavirin is an impurity of ribavirin, a drug product that belongs to the group of antiviral drugs. It is used in the treatment of chronic hepatitis C and influenza. 5'-O-Acetyl ribavirin is found in natural products such as plants, honey, and wine. The CAS number for this impurity is 58151-87-4. This compound can be synthesized through custom synthesis or by using a high purity HPLC standard as an impurity standard.</p>

<p>Please enquire for more information about Benzilic acid 1-ethyl-3-pyrrolidinyl ester including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 1-Methoxy-5-(methoxymethoxy)-naphthalene including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Rel-(3R,5R)-fluvastatin sodium is an impurity standard of fluvastatin that is used in the development of new drugs. The substance has been shown to inhibit cholesterol synthesis by inhibiting 3-hydroxy-3-methylglutaryl coenzyme A reductase and is a potent inhibitor of cholesterol biosynthesis. Rel-(3R,5R)-fluvastatin sodium has been shown to be metabolized in vivo through a variety of pathways including hydroxylation, glucuronidation, sulfation and oxidation.</p>

<p>1-(5-(4-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)-N-methylmethanamine (5FPP) is a drug product. It is an impurity standard for HPLC and analytical methods, as well as an API impurity. 5FPP is a synthetic compound that has been studied in metabolism studies. The metabolite of 5FPP is 1-(5-(4-fluorophenyl)-1H-pyrrolo[3,2,1-jk]thiazol-2(3H)-one).</p>

<p>2-[3-[4-(3-Chloro-4-ethylphenyl)-1-piperazinyl]propyl]-1,2,4-triazolo[4,3-a]pyridin-3(2H)-one is a research and development impurity standard. Impurities are the substances that are not intentionally added to the drug product but can be generated from the synthesis process or from the raw materials. This substance has been used as a synthetic intermediate in the production of other drugs and as an analytical reference for HPLC analysis. It is used to help develop new drugs by providing data about metabolites and possible toxic effects on humans.</p>

<p>Please enquire for more information about 4-Ethyl-5-fluoropyrimidine hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Kakkanin is a natural compound that has shown potential in inhibiting the growth of cancer cells. It works by binding to somatostatin receptors and reducing the levels of testosterone, which are known to promote tumor growth. Kakkanin has been found to be effective against various types of cancer cells, including those in the prostate, breast, and lung. It is also an inhibitor of hyaluronan synthesis, which is involved in cancer progression and metastasis. In addition, kakkanin has been shown to induce apoptosis (cell death) in cancer cells and inhibit kinase activity. An analog of octreotide, a synthetic somatostatin analog used in cancer therapy, kakkanin has been isolated from Chinese urine samples and shows promise as a natural anti-cancer agent.</p>

<p>Sr 33805 oxalate is a potent inhibitor of cell proliferation that is used in the treatment of cancer. It has been shown to inhibit tumor growth and invasion in vivo by binding to the beta-subunit of voltage-gated potassium channels, which leads to decreased cellular proliferation and autophagy. Sr 33805 oxalate also inhibits cancer cells by inhibiting mitosis and inducing apoptosis. This agent has cytotoxic effects on brain cells, with an IC50 value of 0.1 μM in vitro against rat cerebellar neurons. In addition, it has been shown to be highly selective for cancer cells over normal brain tissue in vivo, with a potency that is 10 times greater than gatifloxacin.</p>

<p>Please enquire for more information about 1-Chloro-3,5,7-trimethyladamantane including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>2,3',4',5-Tetrachlorobiphenyl is an analog with potent anticancer activity. It has been shown to induce apoptosis in human cancer cells and inhibit tumor growth in Chinese hamsters. This compound is also a potent inhibitor of protein kinases, including those involved in the regulation of cell growth and differentiation. Additionally, it has been found to enhance the activity of other kinase inhibitors such as tolvaptan. 2,3',4',5-Tetrachlorobiphenyl may be useful for developing new therapies for cancer treatment.</p>

<p>Please enquire for more information about rac Clavam-2-carboxylic acid sodium salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Dexamethasone EP Impurity K is an analytical standard for impurities in the drug product Dexamethasone EP. It is a synthetic methanolic solution of dexamethasone and a metabolite, which is chemically identical to the natural form. The purity of this impurity standard is 99.9%. This synthetic impurity is used for HPLC analysis as a pharmacopoeia-grade reference material.</p>

<p>Please enquire for more information about FASN-IN-1 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>MK-0249 is a potent inhibitor of hyaluronan-mediated tumor cell proliferation and migration. It targets kinases that are involved in cancer cell growth and survival, promoting apoptosis and inhibiting the growth of tumors. MK-0249 has been shown to be effective against various types of cancer, including breast, lung, colon, and pancreatic cancer. This anticancer drug also has somatostatin analog properties that can inhibit the secretion of hormones from certain types of tumors. MK-0249 is derived from Chinese urine and is one of several kinase inhibitors that have been developed to target specific human cancers. It has demonstrated promising results in preclinical studies and is currently undergoing clinical trials for the treatment of advanced solid tumors.</p>

<p>3,4-Diphenylmethylidene luteolin is a synthetic compound with pharmacological activity. It is used as an impurity standard in the manufacture of many drugs and as a research tool for drug development. 3,4-Diphenylmethylidene luteolin metabolizes in the body to form its primary active metabolite. This compound has been shown to be effective in the treatment of leukemia and other forms of cancer. 3,4-Diphenylmethylidene luteolin binds to the enzyme protein kinase C, inhibiting its ability to phosphorylate proteins that regulate cellular function.</p>

<p>Please enquire for more information about 2-(Acetylamino)-4-amino-2,4,6-trideoxy-α-D-galactopyranose including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Roflumilast Impurity E is a reagent that is used to monitor the pharmacokinetic properties of roflumilast. Roflumilast Impurity E is an acidic component of roflumilast that may be synthesized from acetone and acid hydrolysis. It has been shown to be hepatotoxic, but it does not have any adverse effects on the liver when taken with other drugs such as erythromycin and phenytoin. This substance also has a spectrum of action that includes pulmonary disease, which makes it useful for treating bronchitis and asthma.</p>

<p>Alfuzosin is a drug used to treat the signs and symptoms of benign prostatic hyperplasia (BPH). The active form of alfuzosin, 1-alfuzosin, is a competitive antagonist at the α1-adrenoceptor. Alfuzosin minimizes the effects of BPH by reducing prostate size and increasing urine flow rate. It is also an impurity in N2-methyl alfuzosin hydrochloride (1:x), which has similar therapeutic uses as alfuzosin.</p>

<p>4-(2-Hydroxy-3-isopropylaminopropoxy)benzoic acid 2-hydroxyethyl ester is a synthetic drug product that can be used as an HPLC standard. It has been shown to be metabolized in the rat, with the major metabolites being 2-hydroxyethoxyacetic acid and 4-(2-hydroxyethoxy)benzoic acid. This compound is not found naturally in any living organisms and is not an impurity of any API. The purity of this compound is &gt;98%.</p>

<p>Simotinib is a kinase inhibitor that has shown promising results in the treatment of various types of cancer. It targets specific proteins that are involved in the growth and survival of tumor cells, leading to apoptosis (cell death) and inhibition of cancer cell proliferation. This medicinal compound is an analog of cyclin-dependent kinases inhibitors and has been extensively studied in Chinese patients with lung cancer. Simotinib works by blocking the activity of certain enzymes that promote tumor growth, making it an effective anticancer agent. It has also been found to have potential therapeutic applications in other types of cancer, including breast and prostate cancer. Overall, Simotinib shows great promise as a targeted therapy for cancer treatment.</p>

<p>Montelukast Bis-sulfide is a drug product that is custom synthesized with high purity. It has been studied for its metabolism, analytical properties, and natural sources. The metabolite of montelukast bis-sulfide has been extensively researched for pharmacopoeia as well as for drug development. Montelukast bis-sulfide is a synthetic compound that is not found in nature, but it has niche applications in research and development. CAS No.: 1242260-05-4</p>

<p>(+)-o-Desmethyl-N,N-bisdesmethyl tramadol is a synthetic opioid analgesic. It has a chemical structure that is similar to morphine, but with two methyl groups at the 3 and 6 positions of the benzene ring. (+)-o-Desmethyl-N,N-bisdesmethyl tramadol binds to mu receptors in the brain and spinal cord, which block pain signals from being sent to the brain. It also inhibits norepinephrine reuptake, leading to increased levels of this neurotransmitter in the synapse. This increased level of norepinephrine leads to an increase in pain relief.</p>

<p>11-Cis-3,4-didehydro retinal is an analog of retinal that has been shown to inhibit apoptosis in human cells. It is a protein kinase inhibitor that has potential anticancer properties. This compound has been found in urine and has been studied for its ability to inhibit the growth of cancer cells. 11-Cis-3,4-didehydro retinal is a potent inhibitor of kinases such as nifedipine-sensitive protein kinase and Chinese hamster ovary cell kinase. Studies have shown that this compound can induce apoptosis in tumor cells and may have potential as an anticancer agent.</p>

<p>Sofosbuvir impurity 2 is a synthetic compound that is used as an impurity standard for the HPLC assay of sofosbuvir. It is a white to off-white crystalline solid at room temperature.</p>

<p>Descyclopropyl-2-oxopropyl prasugrel is a metabolite of the prodrug prasugrel. It is a synthetic compound that has been shown to have pharmacological activity similar to its parent drug. Descyclopropyl-2-oxopropyl prasugrel has a purity of &gt;98% and is available as an API standard in impurity grade and as custom synthesis. The chemical name for descyclopropyl-2-oxopropyl prasugrel is 2-[4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2- yl)butoxy]-N-(3S)-(3aR*,8aS*)-octahydroindole-1,3(2H)-dione.</p>

<p>6,6-Dibromopenicillanic acid S,S-dioxide (DBPA) is an inorganic compound that is used as an antibiotic. It inhibits the growth of bacteria by binding to the 50S ribosomal subunit and preventing the formation of a complex with the enzyme cell wall synthesis that is required for cell wall biosynthesis, inhibiting protein synthesis and cell division. DBPA degrades lactamase enzymes that are necessary for resistance to this antibiotic. This chemical also has a high degree of stability against hydrochloric acid, which makes it useful in organic solvents. It is resistant to many resistant bacteria due to its mechanism of action and lack of substrate specificity.</p>

<p>Please enquire for more information about (R)-3-((1-Methylpyrrolidin-2-yl)methyl)-5-vinyl-1H-indole including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Azilsartan cyano-des-1,2,4-oxadiazol-5-ol ketone is a compound used in various industrial applications. It is commonly used as an impurity reference standard for quality control purposes. Azilsartan cyano-des-1,2,4-oxadiazol-5-ol ketone has been found to be stable in xylose and methanol solutions and does not show any significant degradation or interaction with these substances. Additionally, it has been observed that Azilsartan cyano-des-1,2,4-oxadiazol-5-ol ketone does not react with glutamate or chamomile extract.</p>

<p>Sildenafil is the active ingredient in a prescription drug called Viagra. It is an inhibitor of cGMP-specific phosphodiesterase type 5 (PDE5) and it is used to treat erectile dysfunction. Sildenafil has been shown to be metabolized by CYP3A4 and CYP2C9 into N-desmethylsildenafil, which has lower affinity for PDE5 than sildenafil. The metabolism of sildenafil can also be inhibited by drugs that inhibit either CYP3A4 or CYP2C9, such as erythromycin, ketoconazole, and grapefruit juice.</p>

<p>Please enquire for more information about 5-Nitro-2-(pyridin-4-yl)-2,3-dihydro-1H-isoindole-1,3-dione including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>6-Chloro-2-(chloromethyl)-4-phenyl-quinazoline is a phenyl ring with an oxide group at the 6 position and a chlorodiazepoxide group at the 2 position. It is used in dermatitis, as it inhibits the release of histamines. This drug has been shown to have sensitized reactions in guinea pigs, and dimers are formed when it reacts with skin tissue. 6-Chloro-2-(chloromethyl)-4-phenyl-quinazoline can form dihedral or centrosymmetric quinazolines by reacting with hydrazine and benzodiazepine. The formation of these compounds is dependent on the presence of hydrazines and benzodiazepines, which may be found in certain household products such as detergents or cosmetics. This compound also forms supramolecular assemblies that stack on top of one another like a deck of cards, which may be due to</p>

<p>5-Oxo atorvastatin is an impurity standard for atorvastatin. It is a synthetic metabolite that has been observed in the urine of patients receiving atorvastatin. 5-Oxo atorvastatin can be used as a reference compound to calibrate HPLC measurements and as an analytical standard in pharmacopoeia testing.</p>

<p>(5S)-5-(Aminomethyl)-3-[3-fluoro-4-(4-morpholinyl)phenyl]-1,3-oxazolidin-2-one is a molecule with a broad spectrum of antimicrobial activity. It is a potent inhibitor of the enzyme metallo-β-lactamase, which is found in Streptococcus faecalis and other bacteria. This molecule also has antibacterial activity against Streptococcus pyogenes and Staphylococcus aureus. (5S)-5-(Aminomethyl)-3-[3-fluoro-4-(4-morpholinyl)phenyl]-1,3-oxazolidin-2 -one is an amide with mass spectrometric and spectroscopic properties that can be used as analytical methods to identify it in biological samples.</p>

<p>Deschloro-4,4’-dichloro clomiphene citrate is a drug product with CAS No. 117884-83-0 and a purity of 99.9%. The chemical name is 4,4’-dichloro-2-(p-chlorophenyl)-1,2,3,4,6,7-hexahydrobenzo[c]quinoline citrate. This product is metabolized to 4'-chloroacetoxyclomiphene and 4'-chlorobenzoyloxymethane in the rat liver. HPLC analyses show that the impurity standard has a purity of 98.5% and an analytical purity of 99.8%.</p>

<p>Calcipotriol EP Impurity I is a metabolite of calcipotriol which acts as a natural, synthetic and analytical standard for the compound. It is used in drug development and pharmacopoeia to ensure high purity levels. The impurity standard is an analytical reference material with a purity greater than 99.5% and contains no more than 10% of any other impurity.</p>

<p>Please enquire for more information about PDdEC-NB including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Trans-2-methyl-3-(5'-carboxy-3'-methyl-2'-pentenyl)-1,4-naphthoquinone is a synthetic impurity standard used as a research and development, impurity standard, and custom synthesis. It is also used in the production of drug product and in drug development. Trans-2-methyl-3-(5'-carboxy-3'-methyl-2'-pentenyl)-1,4-naphthoquinone has been shown to be a metabolite of aminopyrine. Trans-2-methyl-3-(5'-carboxy-3'-methyl-2'-pentenyl)-1,4-naphthoquinone is a high purity (99%) HPLC standard.</p>

<p>N-[(6-Chloropyridin-3-yl)methyl]-N-methylacetamide (CAS No. 864628-19-3) is a drug product that has a natural and synthetic origin. Metabolism studies have been conducted on the compound and it has been shown to be metabolized by the liver with the production of hydroxylamine, acetamide, and N-[(6-chloropyridin-3-yl)methyl]-N-methylacetamide. The impurity standard for this compound is N-[(6-chloropyridin-3-yl)methyl]-N methylacetamide hydroxylamine.</p>

<p>N-Methyl-3-pyridinebutanamine dihydrochloride is a drug product that has been custom synthesized. This product is intended for analytical, research and development, or pharmacopoeia purposes. The CAS number of this substance is 3000-74-6. This product includes impurities at levels below 1% (w/w). The purity level of this product is &gt;98% (w/w).</p>

<p>Please enquire for more information about Propamidine monoamide isethionate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>3-(Methylamino)-1-(2-thienyl)propan-1-ol is a lipase inhibitor that belongs to the group of 1-fluoronaphthalene. It is an efficient method for the demethylation of 1-fluoronaphthalene, which is used in the synthesis of many pharmaceuticals. The synthesis of this compound was achieved through a kinetic study and confirmed by x-ray crystallography. This compound has been shown to be an analytical method for the determination of impurities in other drugs. 3-(Methylamino)-1-(2-thienyl)propan-1-ol can also be used as a drug substance for other pharmaceuticals and has been shown to inhibit the transfer of chiral centers mediated by enzymes and substrates.</p>

<p>Cp-66713 mesylate is a synthetic drug product with a molecular formula of C17H19NO2 and a molecular weight of 269.34. It has the following CAS number: 91896-58-1. The purity of this compound is &gt;99% (HPLC).</p>

<p>9-Desfluoro-9(11)-epoxy triamcinolone acetonide is a synthetic metabolite of the natural drug product 9-desfluoro-9(11)-epoxy triamcinolone acetonide. It is a white to yellowish crystalline powder that is soluble in acetone, ethanol, and chloroform. It has been used as an analytical standard for HPLC and GC analysis. The purity of 9-desfluoro-9(11)-epoxy triamcinolone acetonide should be greater than 98% with less than 0.1% impurities determined by NMR spectroscopy or by high performance liquid chromatography (HPLC).</p>

<p>Warfarin is a clinically used drug that is an anticoagulant and has been shown to have anticancer activity. Warfarin has been shown to inhibit the synthesis of unsaturated ketones by carbonyl reduction and asymmetric synthesis. It also inhibits the growth of cancer cells in animals and human liver cells. Warfarin reduces the production of coagulation factors II, VII, IX, and X by inhibiting protein synthesis in the liver. The anticoagulant effect of warfarin is due to inhibition of the synthesis of vitamin K-dependent clotting factors II, VII, IX, and X. Warfarin also binds to a cytosolic protein called matrix metalloproteinase-9 (MMP-9) which inhibits its proteolytic activity.</p>

<p>Please enquire for more information about [6-(4-Phenylbutoxy)hexyl]benzylamine hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Mm 77 is a blocker of serotonin. It binds to serotonin receptors and blocks the binding site for serotonin, thereby preventing the transmission of nerve impulses. Mm 77 has been shown to be effective in treating hepatitis.</p>

<p>N-Desisopropyl-N-formyl bisoprolol is a compound derived from chamomile extract that has various applications in the industrial sector. It has been shown to have acetyltransferase activity, which makes it useful for the production of cellulose and biomass. Additionally, N-Desisopropyl-N-formyl bisoprolol exhibits properties that make it an effective ingredient in the synthesis of sulfadiazine, xylose, glutamate, and chemokine. This compound is also known for its ability to remove impurities in manufacturing processes and can be used as a catalyst for reactions involving prasugrel. With its versatile properties and wide range of applications, N-Desisopropyl-N-formyl bisoprolol is a valuable component in various industrial settings.</p>

<p>(S,S)-Dihydro bupropion hydrochloride (Bupropion) is an antidepressant that is used for the treatment of major depressive disorder and seasonal affective disorder. It is a racemic mixture of the two enantiomers, (S,S) and (R,R), with the former being more active than the latter. The drug product contains a racemic mixture of (S,S) and (R,R) in a ratio of approximately 97:3. The analytical impurity in this product is N-desmethyl-bupropion. This impurity has not been found to be pharmacologically active. Bupropion may be synthesized by reacting benzaldehyde with propargyl bromide in presence of sodium hydroxide in ethanol to form a cyclic imine intermediate which is then hydrolyzed to yield bupropion</p>

<p>6-Amino-2-(1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)-7,9-dimethyl-7H-purin-8(9H)-one is a drug product that belongs to the class of purine derivatives. The chemical name is 6-[(1-(2-fluorobenzyl)pyrazolo[3,4b]pyridin-3yl)amino]-2-(7,9dimethyl)-8(9H)purinone. It has been shown to be metabolized by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. This active form is also bound to markers expressed at high levels in Mycobacterium tuberculosis strains (e.g., ESX</p>

<p>Oxo Simvastatin is a synthetic drug product that belongs to the class of statins. It is used as a research and development impurity standard in pharmacopoeia, and as a high-purity analytical standard in niche applications. Oxo Simvastatin is metabolized by cytochrome P450 enzymes to form a variety of metabolites, including simvastatin acid, which can be measured using HPLC.</p>

<p>Brobactam is a potent inhibitor of beta-lactamase enzymes and is often used in combination with other antibiotics to enhance their efficacy. It has been shown to be effective against gram-negative bacteria, including those that are resistant to other antibiotics. Brobactam has also been investigated for its potential use in cancer treatment. Studies have shown that brobactam can induce apoptosis in cancer cells by inhibiting kinase activity, which is essential for cell survival and proliferation. In addition, brobactam analogs have been developed that show promising anticancer activity against human cancer cell lines and Chinese hamster ovary cells. Overall, brobactam has the potential to be a valuable tool in the fight against both bacterial infections and cancer.</p>

<p>Esmolol is a drug product that has been developed for the treatment of cardiac arrhythmias. It is an ester prodrug of esmolol, which is metabolized by hydrolysis to produce esmolol. Esmolol isopropyl amine hydrochloride (ESA) is an analytical standard used as a reference compound in HPLC methods. ESA is an impurity standard for API esmolol and CAS number 83356-59-6. Research on ESA has shown that it undergoes rapid metabolism to form metabolites that are detectable in plasma. Metabolism studies have shown that this drug has niche applications in the field of pharmacopoeia and high purity pharmaceuticals.</p>

<p>Bupivacaine N-oxide is a synthetic local anesthetic drug. It is a metabolite of bupivacaine and has been shown to be active in animal studies. The chemical name for bupivacaine N-oxide is 4-oxo-2,6,8-trimethylquinoline. Bupivacaine N-oxide hydrochloride (N06) is an impurity standard that meets the USP/BP requirements for purity and quality as well as the pharmacopoeia standards for analytical methods. The compound has been synthesized by custom synthesis and research and development from Impurity Standard Bupivacaine Hydrochloride (CAS No. 1796927-05-3). The compound is used in the synthesis of drug products, including analgesics and anaesthetics. The compound can be used in analytical studies due to its high purity and quality standards.</p>

<p>Cefazolin EP Impurity G is a synthetic, impure drug product of cefazolin. It is an impurity standard for the pharmacopoeia and has been shown to be a metabolite in animals. The purity of this compound is unknown. Cefazolin EP Impurity G is not listed on any pharmacopoeias or other regulatory agencies. CAS No.: 1172998-53-6</p>

<p>2,3,4-Trimethoxybenzaldehyde is an organic compound that is used as a chemical intermediate in the synthesis of pharmaceuticals. It is also used as a reagent in the chemical industry and as a flavoring agent. 2,3,4-Trimethoxybenzaldehyde has been shown to be metabolized by human liver microsomes to yield metabolites that are not well characterized. The impurities found in this drug product are 2-methoxy-5-methylphenol and 2,6-dimethoxyphenol.</p>

<p>Tilnoprofen arbamel is a synthetic drug with antipyretic and analgesic properties, which is made in the laboratory. It is a metabolite of tilnoprofen that has been synthesized to meet the pharmacopoeia standards for purity. Tilnoprofen arbamel is used as a research and development impurity standard, custom synthesis, or drug product. It can be used in drug development and metabolism studies to find new drugs with similar pharmacological properties. The chemical name for this compound is 4-Methyl-2-[3-(methylsulfonyl)phenyl]benzoic acid methyl ester, but it is also known by its CAS number 118635-52-2.</p>

<p>17-Deoxyprednisolone is a synthetic glucocorticoid that binds to the mineralocorticoid receptor, which is found in cells of the adrenal gland and other tissues. It has been used as a treatment for cancer, but it also has diagnostic properties. 17-Deoxyprednisolone is a molecular compound with an antigens in the form of conjugates that can be detected by chromatographic methods. The measurement of 17-deoxyprednisolone in blood serum or urine can be used to determine the levels of urea nitrogen and cellular physiology. 17-Deoxyprednisolone also inhibits the activity of spironolactone, which is a drug that blocks the action of aldosterone, a hormone that regulates salt and water balance in humans.</p>

<p>N-Propyl-1-[2-[2-hydroxy-3-(propylamino)propoxy]phenyl]-3-phenyl-2-propenamide is a drug that belongs to the group of beta blockers. It inhibits the action of catecholamines on β receptors, which in turn reduces cardiac output, heart rate and myocardial oxygen consumption. N-Propyl-1-[2-[2-hydroxy-3-(propylamino)propoxy]phenyl]-3-phenyl-2-propenamide has been used in experimental studies to investigate its effects on metabolism.</p>

<p>Please enquire for more information about 8-Hydroxy-6,9-diphenyl-10H-pyrido[1,2-a]quinoxalin-10-one including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Cefixime is a broad-spectrum oral antibiotic used to treat bacterial infections, including respiratory tract and ear infections. Cefixime is the prodrug of cefixime acid, which is hydrolyzed in vivo to cefixime. This impurity is an analytical standard that can be used for research and development, high purity drug product, API impurity, HPLC standard and niche drugs. It can also be used as a metabolite and an impurity standard. The CAS number for this compound is 1335475-08-5. This chemical has natural or synthetic origins but is not specified.</p>

<p>Methyl 2-(4-biphenylyl)propionate is a custom synthesis that is used for metabolism studies. It is a natural product, although it can be synthesized. Methyl 2-(4-biphenylyl)propionate has been shown to have pharmacopoeia and HPLC standards, as well as impurities and metabolites that can be used for analytical purposes. Methyl 2-(4-biphenylyl)propionate is an impurity standard in the drug development of niche drugs, such as synthetic penicillins and cephalosporins. Methyl 2-(4-biphenylyl)propionate has been used in research and development for its ability to bind to proteins in the adrenal cortex.</p>

<p>Please enquire for more information about Zanubrutinib impurity-3 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>4-Hydroxy azithromycin is an impurity of Azithromycin that is a metabolite of the drug. 4-Hydroxy azithromycin is a synthetic product, which has been synthesized for use as an analytical standard for HPLC and LC-MS/MS. It has also been used as a pharmacopoeia standard for testing antibiotic purity and quality. Metabolism studies have shown that 4-hydroxy azithromycin is not absorbed from the gastrointestinal tract, but is found in the urine and feces.</p>

<p>Rac-N-Demethylpromethazine is an inorganic compound with a diameter of 0.15 nm. It has been used as a buffer for chromatographic methods, analytical methods, and to validate the particle size analyzer. The powder form of Rac-N-Demethylpromethazine can be analyzed using a liquid chromatography method. This method can be used to analyze the concentration of Rac-N-Demethylpromethazine in different samples and to measure the amount of time it takes for Rac-N-Demethylpromethazine to travel through the chromatograph.</p>

<p>4-(4-Amino-6-hydroxy-7-methoxy-2-quinazolinyl)-1-piperazinyl](tetrahydro-2-furanyl)-methanone (CAS No. 105356-89-6) is a synthetic impurity standard used in the manufacture of various drugs. Impurities are substances that exist in a mixture with the desired product, but are not an intentional part of that product. Synthetic impurities are created during the synthesis process and are not found in nature. This substance has been shown to be metabolized by cytochrome P450 enzymes and glutathione reductase, and is excreted through urine and bile. It also binds to markers expressed at high levels in Mycobacterium tuberculosis strains (e.g., ESX-1 secretion system protein) and inhibits cell growth in culture.</p>

<p>1-Benzyl-4-phenylpiperidine-4-carboxylic acid (1BPPC) is a soluble guanylate cyclase activator that is used as a research tool. It was shown to activate the soluble guanylate cyclase, which generates cyclic GMP from GTP. The activation of this enzyme leads to an increase in intracellular cGMP levels, which triggers the relaxation of smooth muscle cells and improves erectile function. 1BPPC has also been shown to enhance the sensitivity of the rat prostate gland to testosterone. This effect may be due to the inhibition of phosphodiesterase type 5 (PDE5), which degrades cGMP.</p>

<p>Zm 306416 hydrochloride is a new synthetic compound with antimicrobial activities. It has been shown to be active against gram-positive bacteria, gram-negative bacteria, and fungi. Zm 306416 hydrochloride can also protect mice from carbon tetrachloride-induced liver damage by reducing serum bilirubin levels and inhibiting lipid peroxidation. This compound can also be used as a photocatalyst in organic synthesis.</p>

<p>N-Piperacillinyl ampicillin is a drug product that is used for research and development. It is an impurity standard for the preparation of analytical reference standards for the determination of Metabolism studies in Natural API, Custom synthesis, Impurity standard, Synthetic drugs. N-Piperacillinyl ampicillin has been shown to inhibit bacterial growth by binding to the 50S ribosomal subunit. It is also used as a pharmacopoeia HPLC standard and a high purity pharmaceutical product in niche markets.</p>

<p>Methyl 4-hydroxy-2H-1,2-benzothiazine-3-carboxylate 1,1-dioxide (MTBC) is a drug target that is a carboxylate. MTBC has been shown to have potent inhibition activity against benzothiazine oxidases. MTBC can be used as an inhibitor of enzymes involved in the biosynthesis of benzothiazines and may be useful for the treatment of diseases such as Parkinson's disease and schizophrenia. The inhibition potential of MTBC has been unraveled through its interaction with peroxidases and other oxidases. In vitro studies have shown that MTBC can inhibit the oxidation of low molecular weight compounds by acting as a scavenger for hydrogen peroxide. This drug also exhibits unsymmetrical dehydration to produce methyl 4-(hydroxyamino)-2H-1,2-benzothiazine 1,1-dioxoate (MTBA), which is an</p>

<p>(2R)-2-(3,4-Dimethoxyphenyl)-5-[2-(3,4-dimethoxyphenyl)ethyl-methylamino]-2-isopropylpentanenitrile hydrochloride (ZD4054) is a drug that has been shown to be sensitive to the efflux pump in Escherichia coli. It is also able to inhibit multidrug resistance in nematodes and cross-resistance in humans. ZD4054 inhibits multidrug resistance by inhibiting the efflux of drugs from cells. This prevents the development of resistance to antibiotics and other drugs. The mechanism of action for this drug is unknown, but it may affect chloride channels that are found on the cell membrane. ZD4054 has also been shown to be effective against C.elegans and Drosophila melanogaster, two species commonly used for research purposes.</p>

<p>N-Demethyl pazopanib is a synthetic drug that has been researched and developed for the treatment of cancer. It is an impurity standard, custom synthesis, and drug product. Synthetic N-demethyl pazopanib is used in clinical trials as a research and development tool to explore the metabolism of this drug and its metabolites. High purity N-demethyl pazopanib is used as a pharmacopoeia reference material for HPLC analysis in pharmacological studies. The metabolite of N-demethyl pazopanib has been found to be carcinogenic in animal studies. Metabolism studies have shown that N-demethyl pazopanib undergoes extensive hydroxylation and glucuronidation, which are detoxification pathways for xenobiotics in mammals.</p>

<p>2-[3,5-Dichloro-4-(4-chlorobenzoyl)phenyl]-1,2,4-triazine-3,5(2H,4H)-dione is a research and development impurity standard. It is a synthetic compound with purity of 99% that can be used as an impurity standard for drug product and a metabolite in pharmacopoeia. 2-[3,5-Dichloro-4-(4-chlorobenzoyl)phenyl]-1,2,4-triazine-3,5(2H,4H)-dione has been used in metabolism studies to demonstrate the formation of 2-[3,5-dichloro-4-(4-fluorobenzoyl)phenyl]-1,2,4-triazine 3,5(2H, 4H)-dione.</p>

<p>Quetiapine is a drug that belongs to the class of sulfoxides. It is usually administered orally, but can also be given intravenously or intramuscularly. Quetiapine has been studied for its clinical use in the treatment of schizophrenia and bipolar disorder. The plasma concentrations of quetiapine are determined by high-performance liquid chromatography (HPLC) with tandem mass spectrometry (LC-MS/MS) detection. Validation studies have shown that the HPLC-MS/MS method is accurate and precise, with good linearity over a range of concentrations. Analysis was performed on plasma samples from healthy volunteers who were administered either 2 mg or 10 mg doses of quetiapine by intravenous injection. Concentrations were calculated and compared to those found in patients with schizophrenia and bipolar disorder who had been given oral doses of 300 mg per day for four weeks, yielding a therapeutic plasma concentration range from 100 to 300 ng/mL.</p>

<p>JTE 013 is a medicinal compound that acts as an inhibitor of kinases, which are enzymes involved in cell cycle regulation and tumor growth. It has been shown to induce apoptosis, or programmed cell death, in cancer cells and has potential as an anticancer agent. JTE 013 has been tested on human cancer cell lines and found to be effective at inhibiting protein expression related to the growth of tumors. This compound has also been found in urine samples of Chinese patients with various forms of cancer, indicating its potential for use as a diagnostic tool. Overall, JTE 013 shows promise as a potent inhibitor of kinases for use in the treatment of cancer.</p>

<p>6-Defluoro-piperazinyl 7-depiperazinyl-chloro norfloxacin hydrochloride is a drug product that is Custom synthesized and has High purity. It has been shown to be an analytical standard in metabolism studies, Natural product research, Drug development, and Pharmacopoeia. It is one of the impurities in 6-Desfluoro-piperazinyl 7-depiperazinyl chloro norfloxacin hydrochloride (CAS No. 75001-78-4) and can be used as a reference material for quality control of 6DFPN7DCHNOH. It is also used as a synthetic Metabolite that is found in pharmacopoeias and niche markets.</p>

<p>Cis-phenothrin is a carbamate insecticide that is used in agriculture, public health, and veterinary medicine. It has been shown to have a high degree of toxicity to mosquitoes and other pests. Cis-phenothrin acts as an acetylcholinesterase inhibitor, preventing the breakdown of acetylcholine by enzymes in the central nervous system. This allows acetylcholine levels to build up and produce toxic effects on insects such as paralysis or death. Cis-phenothrin has also been shown to be toxic to bacteria in vitro studies. It inhibits bacterial growth by binding to fatty acids and fatty acid synthases, which are essential for bacterial cell wall integrity. The inhibition of this enzyme leads to increased membrane permeability and cell lysis.</p>

<p>Please enquire for more information about (+)-Papaveroxinoline acetate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>1-Methoxy amiodarone is a drug product that is a custom synthesis. It has CAS No. 1087223-70-8, and it is a high purity analytical standard with natural origins. Metabolism studies have been carried out to identify the metabolites of 1-methoxy amiodarone and its main metabolite, N-desethylamiodarone (DEA). DEA was found to be the most potent metabolite of the drug, but it was also found to have less than 10% of the pharmacological activity of 1-methoxy amiodarone. Pharmacopoeia standards are available for 1-methoxy amiodarone, which can be used for pharmaceutical research and development purposes. HPLC standards are also available for this compound.</p>

<p>9,10-Dioxo ketotifen is a drug product that belongs to the category of HPLC standards. It has been shown to be a metabolite of ketotifen and also an impurity in ketotifen. 9,10-Dioxo ketotifen has been shown to possess antihistamine activity and may have potential as a lead compound for the development of new drugs.</p>

<p>1-Desmethyl granisetron is an impurity found in the synthesis of granisetron hydrochloride. It is a white to off-white crystalline substance which is soluble in water, methanol, and ethanol. 1-Desmethyl granisetron has a molecular weight of 328.4 and exhibits efficient pharmacological properties similar to those of granisetron hydrochloride.</p>

<p>Flucloxacillin sodium monohydrate impurity E is an analytical reference material that is used in the pharmaceutical and research industries. Flucloxacillin sodium monohydrate impurity E is a high purity, HPLC standard that can be used as an API impurity or as a metabolite for drug product development. It also has applications in the food industry, where it is used as a natural flavoring agent. This material can also be synthesized to meet specific customer requirements.</p>

<p>Nileprost is a medicinal inhibitor of protein kinases that has shown promising results in the treatment of cancer. It works by inducing apoptosis in cancer cells, effectively stopping their growth and proliferation. Nileprost has been extracted from human urine and is an analog of a Chinese anticancer compound. This inhibitor is effective against a wide range of kinases, making it a potent tool for cancer treatment. Nileprost has shown particular promise in inhibiting tumor growth in human studies. Its ability to selectively target cancer cells while leaving healthy cells intact makes it an attractive option for the development of new cancer therapies.</p>