Peptidi
Sottocategorie di "Peptidi"
Trovati 29635 prodotti di "Peptidi"
Myelin Oligodendrocyte Glycoprotein
Myelin Oligodendrocyte Glycoprotein (MOG) is a glycoprotein that is expressed by oligodendrocytes and is essential for the myelinization of axons in the central nervous system. MOG has been associated with the development of multiple sclerosis and demyelinating diseases. Freeze-dried MOG is reconstituted with water before use, which may be beneficial for patients who cannot swallow pills or capsules. The reconstituted protein can be injected intravenously as an allograft. Myelin Oligodendrocyte Glycoprotein can also be used long-term after desiccating to prevent its degradation and loss of biological activity. The expansion of the chromosome carrying the gene for MOG has been shown to be associated with multiple sclerosis and other neurologic diseases.Purezza:>98.0% By Rp-HplcFmoc-N-Amido-dPEG®5-Acid
Fmoc-N-Amido-dPEG®5-Acid is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. Fmoc-N-Amido-dPEG®5-Acid is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.Purezza:Min. 95%EREG Human
EREG Human is a cytokine that belongs to the group of proteins. It is an interleukin-1 receptor antagonist (IL-1Ra) that binds to IL-1 and prevents it from binding with its receptors. EREG Human has been shown to be effective in treatment of inflammatory diseases such as Crohn's disease, rheumatoid arthritis, and ulcerative colitis.Purezza:Min. 95%Dipeptidyl-Peptidase IV, human, recombinant
Dipeptidyl-peptidase IV (DPP4) is a complex enzyme that is expressed in the pancreas and regulates glucose-dependent insulinotropic polypeptides. DPP4 cleaves the amino terminal dipeptide from these polypeptides, which prevents the activation of pancreatic β-cells. The recombinant human form of this enzyme has been shown to activate T cells and induce apoptosis in insect cells. Its activity against chemokines in vitro may be due to its ability to cleave glycosylated polypeptides. This enzyme also has anti-inflammatory effects by inhibiting the production of proinflammatory cytokines such as tumor necrosis factor α (TNFα), interleukin 1β (IL1β), and IL6.
Purezza:Min. 95%2'-5' Oligoadenylate Synthetase 1, human, recombinant
The 2'-5' oligoadenylate synthetase 1 (2-5A-1) is a protein that in humans is encoded by the OAS1 gene. This enzyme catalyzes the synthesis of 2'-5' oligoadenylates, which are potent activators of PKC and MAPK. 2-5A-1 has been shown to increase intracellular calcium levels, activate PKC and MAPK, and induce apoptosis in human cells.Purezza:Min. 95%Anti Nociceptin / Orphanin FQ (Human, Rat) Serum
Anti Nociceptin / Orphanin FQ (Human, Rat) Serum is a peptide that belongs to the family of orphanin FQ peptides. It has been shown to activate ion channels and ligand-gated channels. Anti Nociceptin / Orphanin FQ (Human, Rat) Serum is a high purity, pharmacology research tool for use in cell biology and receptor studies.
Purezza:Min. 95%Bz-Ala-OMe
CAS:Bz-Ala-OMe is a reactive mercuric chloride that undergoes hydrolysis to form reactive mercuric acetate. It has been shown that the activation energy of the reaction is high and the reaction can be initiated by soybean trypsin. The reactive site of Bz-Ala-OMe is composed of chloride atoms and sephadex g-100. This compound reacts with serine proteases, such as trypsin or chymotrypsin, to form an amide intermediate. This intermediate reacts with n-acetyl-l-tyrosine to produce a chloromethyl ketone which then undergoes a nucleophilic attack by histidine to produce histamine in the presence of H2O2 or O2. Histamine binds to H1 receptors in the body, leading to an inflammatory response.
Formula:C11H13NO3Purezza:Min. 95%Peso molecolare:207.23 g/molCRF (Human, Rat, Mouse)-HS ELISA Kit (1ea)
CRF (Human, Rat, Mouse)-HS ELISA Kit is a sandwich ELISA that can be used to detect the human CRF-HS protein in human serum or plasma.Purezza:Min. 95%α Synuclein, human, recombinant
α-Synuclein is a protein that is encoded by the SNCA gene, and is one of the main components of Lewy bodies, which are found in neurons in people with Parkinson's Disease. α-Synuclein has been shown to protect cells from stress and prevent their death. It also acts as a chaperone for other proteins, regulating their activity. This protein has been shown to be able to bind to GTPase activators and inhibit them from activating GTPases. The molecular weight of α-synuclein is 25 kDa and it has a pI value of 4.5. It has an acidic C-terminus and its shift on gel electrophoresis is 11.5 kDaPurezza:Min. 95%Glu-pNA hydrate
Glu-pNA hydrate is a cell-permeant, fluorescently labeled amino acid that selectively binds to ion channels and can be used as a research tool for pharmacology and protein interactions. Glu-pNA hydrate is a high purity product with an antibody activity of less than 0.5% and its CAS number is 1314-77-8. This product has been shown to inhibit the activity of the following proteins: PKCα, phospholipase A2, cyclooxygenase II, and caspase 3. Glu-pNA hydrate also has been shown to activate the following proteins: PKA, PKCβII, PKCγII, PKCδI, PKCεII, PI3KIIIα/β/γ/δ/εIIIa/b/c/d, p38MAPKs, ERK1/2 MAPKs, JNK1/2 MAPK
Formula:C11H13N3O5•H2OPurezza:Min. 95%Peso molecolare:285.26 g/molAnti Humanin Serum
Anti Humanin Serum is a research tool that can be used as a pharmacological reagent or as a research tool. It is an antibody that can be used to study protein interactions, such as receptor-ligand binding, and the effects of peptides on ion channels. This product is composed of high purity humanin antibodies with no detectable cross-reactivity with other proteins.Purezza:Min. 95%Ac-RGDSPGGC-NH2
Peptide Ac-RGDSPGGC-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
Dihydrofolate Reductase, human, recombinant
Dihydrofolate reductase is an enzyme that catalyzes the conversion of dihydrofolate to tetrahydrofolate. It belongs to a family of metalloenzymes that employ NADPH as a cofactor and are involved in one-carbon metabolism. Dihydrofolate reductase has been shown to interact with a number of other proteins, including peptides, cell biology, and receptor. This enzyme is also used as an inhibitor for research purposes.
Purezza:Min. 95%IL 7 Human, HEK
IL-7 is a cytokine that belongs to the IL-2 family. It is a lymphokine that regulates cell proliferation and differentiation of immune cells, such as T and B cells. IL-7 activates these cells by binding to the IL-7 receptor on their surface. The active form of IL-7 is a homodimeric glycoprotein consisting of two subunits, alpha and beta. The alpha subunit has an N-terminal sequence of amino acids (Lysine - Proline - Glycine) while the beta subunit has a C-terminal sequence (Serine - Asparagine). This protein can be purchased as a research tool, antibody, or purified peptide in high purity from Sigma Aldrich.Purezza:Min. 95%GroEL (HSP60) E.coli (recombinant)
GroEL is a protein that is found in bacteria. It is an ATPase and a chaperone, which helps other proteins maintain their correct shape. GroEL can be purified from E. coli or from the bacterium Bacillus stearothermophilus. The recombinant form of GroEL consists of the protein and its co-factor, dithiothreitol (DTT). This protein has been shown to have ion channel activity, which may play a role in cell excitability as well as receptor-ligand interactions. It also binds to peptides and has been used as a research tool for pharmacology, protein interactions, and cell biology studies. GroEL has been shown to activate certain enzymes such as proteases, kinases, phosphatases, and ribonucleotide reductase. It also inhibits other enzymes such as lipases and esterases.Purezza:Min. 95%H-TQETNKVETY-OH
Peptide H-TQETNKVETY-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
Bis-dPEG®3-NHS Ester
CAS:Bis-dPEG®3-NHS Ester is a PEG polymer categorised as homobifunctional PEG (X-PEG X). Used as a linker, bis-dPEG®3-NHS Ester is used to attached PEG to proteins, peptides, oligonucleotides, nanoparticles and small molecules via pegylation, a bioconjugation technique.
Formula:C53H71F4NO15Purezza:Min. 95%Peso molecolare:1,038.14 g/molAnti PACAP38 (22-38)(Human) Serum
Anti PACAP38 (22-38)(Human) Serum is a research tool for the study of Protein Activator of cAMP Catalytic Subunit Protein 38. It is an activator that binds to the receptor and has been shown to activate cell signaling pathways. This antibody can be used to detect PACAP38 in human serum.Purezza:Min. 95%Anti Galanin (Porcine) Serum
Anti Galanin (Porcine) Serum is a research tool that is used to activate, bind, and inhibit the ligand-receptor interactions. It is also used for the study of ion channels and cell biology. Anti Galanin (Porcine) Serum can be used as an antibody or as a peptide in pharmacology studies. The protein interactions are used in life science research, as well as for inhibitor studies.Purezza:Min. 95%Adrenomedullin 2 (Rat)
Adrenomedullin 2, a peptide hormone product, of rat source and has disulfide bond between Cys10-Cys15. Adrenomedullin 2 can be applied as a potent cardiovascular and renal regulator as well as a suppressor for food intake and gastric emptying. This product is available as a 0.1mg vial.Formula:C226H361N75O64S2Purezza:Min. 95%Peso molecolare:5,216.9 g/molZ-Asp-CH2-DCB
CAS:Z-Asp-CH2-DCB is a peptide that is an activator of cell membrane ion channels and receptor proteins. It has been shown to inhibit the interaction between ligands and receptors, thus blocking the binding of chemical signals with their corresponding cells. This chemical signal can be either neurotransmitters or hormones. Z-Asp-CH2-DCB is also a research tool for studying protein interactions and cellular processes, such as ion channel activation.Formula:C20H17NO7Cl2Purezza:Min. 95%Peso molecolare:454.26 g/mol[D-Ala2,Met5]-Enkephalin
CAS:[D-Ala2,Met5]-Enkephalin is an inhibitory neurotransmitter that binds to receptors in the brain and spinal cord. It affects physiological functions such as locomotion, pain sensation, and blood pressure. Enkephalins are analogs of the natural neurotransmitter enkephalin that are synthesized by enzymatic cleavage of the latter from a larger precursor molecule called proenkephalin. [D-Ala2,Met5]-Enkephalin has been shown to be an effective antinociceptive agent when administered intraperitoneally or intravenously in rats. It also acts as a pressor agent and produces dextran sulfate-induced nociception in mice. The pharmacological properties of enkephalins have been shown using various analytical methods including acid analysis.Formula:C28H37N5O7S•CH3COOH•H2OPurezza:Min. 95%Peso molecolare:665.76 g/molInsulin (Rat)
Insulin is a peptide hormone that regulates glucose levels in the blood. It is produced by beta cells in the pancreas and released when blood sugar levels rise. Insulin lowers blood sugar levels, but it also has other functions, such as protein synthesis and cell growth. Insulin stimulates receptors on cells to take up glucose from the bloodstream. Inhibitors of insulin are used for type 1 diabetes mellitus treatment and research purposes. Insulin can be used to study ion channels, antibody production, and receptor binding.Purezza:Min. 95%Bis-dPEG®17-PFP Ester
CAS:Bis-dPEG®17-PFP Ester is a PEG polymer categorised as homobifunctional PEG (X-PEG X). Used as a linker, bis-dPEG®17-PFP Ester is used to attached PEG to proteins, peptides, oligonucleotides, nanoparticles and small molecules via pegylation, a bioconjugation technique.
Formula:C50H72F10O21Purezza:Min. 95%Peso molecolare:1,199.08 g/molIGF1 Mouse
The IGF1 Mouse is a recombinant protein that belongs to the group of cytokines. It is produced by Escherichia coli and secreted into the culture medium. The IGF1 Mouse is used in vitro for the measurement of cytokines and cytokine receptors.Purezza:Min. 95%Guanylate Kinase 1, human, recombinant
Guanylate kinase 1 is a member of the guanylate kinase family. It is a protein that in humans encoded by the GMNK1 gene. Guanylate kinases catalyze the reversible transfer of phosphate groups from ATP to guanosine diphosphate (GDP). They are involved in regulating the balance between GTP and GDP in cells, which has been shown to be important for many cellular processes, including cell signaling, cytoskeletal remodeling and apoptosis. Guanylate kinase 1 is an inhibitor of receptor tyrosine kinases, with an IC50 value of 2 μM. It also has been shown to be able to activate L-type calcium channels at concentrations greater than 100 μM. The recombinant human guanylate kinase 1 used in this study was expressed in E. coli and purified using affinity chromatography.Purezza:Min. 95%Parathyroid Hormone (Human, 1-34)
CAS:This product which is available as a 0.5mg vial is amino acids 1-34 of the 84 amino acid parathyroid hormone (PTH) and can be used as an adenylate cyclase and bone growth stimulating peptide. It is possible that in can be used in research in the treatments of some types of osteoporosis. PTH is a peptide hormone that is secreted from the parathyroid gland in the event of abnormal serum calcium levels and it ultimately regulates calcium and phosphate levels in the body. The PTH exerts its activity through binding to the G-protein coupled receptor type 1 PTH receptor, which activates adenylate cyclase or phospholipase C thus activating pathways involved in the mediation of bone resorption and bone formation. This product is suitable for life science applications.Formula:C181H291N55O51S2Purezza:Min. 95%Peso molecolare:4,117.7 g/molUrocortin II (Mouse)
CAS:Urocortin II is a peptide of the corticotropin-releasing factor receptor family that is synthesized in the brain. It has been shown to inhibit the activity of other peptides and proteins, and can be used as a research tool for studying protein interactions, receptor binding, ion channel activity, and ligand binding. Urocortin II has been shown to activate receptors in mouse brain tissue, which may provide insight into its function as a regulator of stress responses.Formula:C187H320N56O50Purezza:Min. 95%Peso molecolare:4,152.9 g/molKLA10
KLA10 is a custom research peptide; min purity 95%, TFA salt. For different specs please use the Peptide Quote Tool
H-IFFVNPAPPYLWPAHK-OH
Peptide H-IFFVNPAPPYLWPAHK-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
monobiotin INSL3
Monobiotin is a small molecule that is an activator of the L3 receptor. It has been shown to be a ligand for the L3 receptor and to activate this receptor in cells. Monobiotin activates cell membrane ion channels by binding to the L3 receptor and has been used as a research tool to study protein interactions. Monobiotin is also an inhibitor of voltage-gated potassium channels, which are important in regulating excitability in nerve cells, and can serve as a pharmacological tool for studying ion channel function.
Purezza:Min. 95%H-TVRHPEW-OH
Peptide H-TVRHPEW-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
Apolipoprotein E C-term Light Tryptic Peptide Standard (4nmol)
An apolipoprotein E C-term light tryptic peptide standard for use in protein identification and quantitation studies. As part of a fat-binding protein family, apolipoprotein E plays a role in the metabolism of fats in the body through interacting with the low density lipoprotein receptor, which is involved in the catabolism of triglyceride rich lipoproteins. Apolipoprotein E is also a major component in cholesterol metabolism and is a carrier of cholesterol in the brain. Additionally when forming a complex with C1q, apolipoprotein E is an inhibitor of the classical complement pathway. The N and C terminal regions of apolipoprotein are connected by a hinge region and the C-terminal region is a hydrophobic surface made up of three alpha helices and a low density lipoprotein receptor binding site.Purezza:Min. 95%H-LESNNYNTYR-OH
Peptide H-LESNNYNTYR-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
m-dPEG®48-OH
m-dPEG®48-OH is a PEG polymer categorised as monofunctional (OH-PEG-X). Used as a linker, m-dPEG®48-OH is used to attached PEG to proteins, peptides, oligonucleotides, nanoparticles and small molecules via pegylation, a bioconjugation technique.Formula:C98H198O49Purezza:Min. 95%Peso molecolare:2,160.59 g/molTAME hydrochloride
CAS:Tos-Arg-OMe • HCl is a peptide that has been shown to modulate the responsiveness of cells to sodium channels. Tos-Arg-OMe • HCl may also be useful as an anti-cancer drug, as it inhibits cancer cell growth and induces apoptosis. This peptide has been shown to be an effective treatment for HIV infection by inhibiting viral replication. It also reduces inflammation and prevents the development of other opportunistic infections in animal models.Formula:C14H22N4O4S·ClHPurezza:Min. 95%Peso molecolare:378.87 g/molTentaGel® M RAM
TentaGel is a water-soluble polymer that can be used as a building block for various applications including drug delivery, food and beverage, cosmetics, and electronics. It consists of two main components: polyethylene glycol (PEG) and polypropylene glycol (PPG). TentaGel is soluble in water and has an average molecular weight of about 10,000 Da. The PEG-based component allows the polymer to be easily processed into particles or fibers by sonication or extrusion. TentaGel M RAM is a modified version of the original TentaGel. It contains methacrylic acid groups that have been grafted onto the PEG backbone to provide additional functionality such as reactive surfaces for conjugation with proteins or other molecules.Purezza:Min. 95%APETx2
CAS:APETx2 is a drug that inhibits the activity of apetx2, a protein which is involved in the regulation of ion channels and endothelin-A receptors. APETx2 has been shown to inhibit the activity of channels involved in pain perception and may have therapeutic potential as a pressor agent. This drug has also been shown to have anti-inflammatory properties, which are likely due to its inhibition of EGF receptor activity. The mechanism of action for this drug remains unclear, but it may work by blocking the channel or receptor for EGF.
Formula:C196H280N54O61S6Purezza:Min. 95%Peso molecolare:4,561 g/molH-QRMHLRQYELL-OH
Peptide H-QRMHLRQYELL-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
APP669-711
APP669-711, also known as Amyloid Precursor Protein (APP) 669-711 or Aβ−3–40, may have a potential use as a biomarker for Alzheimer's disease.Purezza:Min. 95%GsMTx4
CAS:GsMTx4 is a ryanodine receptor agonist that binds to the ryanodine receptor and activates signal pathways. It has been shown to activate mechanosensitive channels and regulate intracellular Ca2+ levels by inducing an increase in Ca2+ release from the endoplasmic reticulum. GsMTx4 has also been shown to have pharmacological effects on cells, as well as physiological effects on Grammostola spatulata, such as inhibition of locomotion and increased mortality. GsMTx4 has also been shown to have antiviral properties against infectious diseases such as influenza, herpes simplex virus-1, and West Nile virus.Formula:C185H273N49O45S6Purezza:Min. 95%Peso molecolare:4,101.89 g/molMiniAp-4 peptide
MiniAP-4 peptide is a short nontoxic derivative of apamin (a neurotoxin from bee venom) used as a blood-brain barrier (BBB) shuttle peptide.
[Asu1,6,Arg8]-Vasotocin
CAS:Vasotocin is a peptide that regulates blood pressure and heart rate by acting on the vasoconstrictor and vasodilator systems. It has been shown to inhibit the binding of vasopressin to its receptor, which may be due to the presence of an Arg8 residue in position 6 of the peptide. Vasotocin also stimulates the release of nitric oxide, which leads to smooth muscle relaxation and vasodilation. Vasotocin is a ligand for receptors in both invertebrates and mammals. It is used as a research tool to study ion channels, antibodies, and other proteins that interact with it. Vasotocin can also be used as an anti-inflammatory drug because it can inhibit leukocyte chemotaxis and adhesion.Formula:C45H70N14O12Purezza:Min. 95%Peso molecolare:999.12 g/mol4-Formyl-Benzamido-dPEG®12-EDA-MAL
4-Formyl-Benzamido-dPEG®12-EDA-MAL is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. 4-Formyl-Benzamido-dPEG®12-EDA-MAL is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.Formula:C44H70N4O18Purezza:Min. 95%Peso molecolare:943.04 g/mol(Pro-Hyp-Gly)10·xH2O
Pro-Hyp-Gly is a polypeptide that inhibits collagenase, an enzyme that breaks down collagen. Collagenase is an enzyme that breaks down the protein collagen, which forms the connective tissue in humans and other animals. Pro-Hyp-Gly has been found to be a potent inhibitor of collagenase, and can be used for treatment of inflammatory diseases such as arthritis or skin lesions. Pro-Hyp-Gly also inhibits enzymes called proteases, which break down proteins outside of cells. Proteases are important in the breakdown of food particles in the stomach.Formula:C120H172N30O41•20H2OPurezza:Min. 95%Peso molecolare:3,051.1 g/molKLPGF
KLPGF peptide is a sequence from egg white albumen. This peptide have recently shown interest for Alzheimer’s disease.
HIST1H2AG, H2AFP, HIST1H2AI, H2AFC, HIST1H2AK, H2AFD, HIST1H2AL, H2AFI, HIST1H2AM, H2AFN MS Calibrator-2 (25nmol)
HIST1H2AG, H2AFP, HIST1H2AI, H2AFC, HIST1H2AK, H2AFD, HIST1H2AL, and H2AFN are histone proteins that are components of the nucleosome. They are involved in regulating gene expression. Histones can be analyzed by a proteomics technique known as TrypTides to identify modifications to the protein's amino acid sequence. The Proteomics Tools Kit provides a number of tools for performing peptide enrichment and analysis of proteins extracted from cells or tissues. In this kit is an MS Calibrator-2 (25nmol) which is used to calibrate mass spectrometers with different capabilities.
Purezza:Min. 95%MBP-B MHC II DRB1*15:01 (84-102)
Myelin Basic Protein (MBP)
MBP-B (84-102) DRB1*15:01 is a short part of the myelin basic peptide. Myelin basic protein is one of the major protein found in myelin.
MBP-B (84-102) DRB1*15:01
MBP-B (84-102) DRB1*15:01 is used to stimulate immune response and T cell activity. MBP-B (84-102) DRB1*15:01 is also considered as a reference positive control in binding affinity with DRB1*15:01 molecules.Gla17,21,24-Osteocalcin (Human)
CAS:Gla17,21,24-Osteocalcin is a peptide that belongs to the family of proteins that have bone-building properties. Osteocalcin is produced by osteoblasts and its production increases in response to activation by parathyroid hormone. It is also an activator of ion channels and has been found to be involved in regulating calcium homeostasis. Gla17,21,24-Osteocalcin has been shown to inhibit protein interactions with the receptor and ligand. This peptide also binds to receptor sites on cells and inhibits the activity of G protein-coupled receptors (GPCRs).
Formula:C269H381N67O82S2Purezza:Min. 95%Peso molecolare:5,929.4 g/molAlpha-2-Macroglobulin Heavy Tryptic Peptide Standard (4nmol)
An Alpha-2-Macroglobulin heavy tryptic peptide standard for protein identification and quantitation studies. Alpha-2-Macroglobulin is a broad spectrum protease inhibitor which also plays roles in cell migration and in the binding of growth factors and cytokines.Purezza:Min. 95%H-LQEYTQTILR-OH
H-LQEYTQTILR-OH is a custom research peptide; min purity 95%, TFA salt. For different specs please use the Peptide Quote Tool
Ac-Tyr-Val-Ala-Asp-AMC
CAS:Ac-Tyr-Val-Ala-Asp-AMC is a peptide that is used as a research tool to activate ion channels in cells and study the effects of ligands on these channels. It is also used in cell biology to study protein interactions, although it does not bind to any specific receptor. Ac-Tyr-Val-Ala-Asp-AMC belongs to the group of inhibitors and can be used for pharmacological purposes. The chemical structure of this peptide consists of a covalent bond between an amino acid and an acetylated form of a fluorescent molecule, which makes it suitable for use in fluorescence microscopy. Acetylated Tyr (Ac-Tyr) is one of the six amino acids found in proteins and has the ability to inhibit the activity of ion channels by binding to their external cavity. Acetylation at position 2 or 3 on Tyr can increase its affinity for calcium ion channels and affect their activation or deFormula:C33H39N5O10Purezza:Min. 95%Peso molecolare:665.69 g/molMouse Beta-Defensin 3 peptide
mouse Beta-Defensin 3 peptide (mBD3), a homolog of human beta-defensin 2 (hBD2), is a cysteine-rich cationic antimicrobial peptide of 41 amino acids which belongs to the defensins family.
Defensin peptides are cationic peptides originally produced in various organs. They are involved in the protection against different kinds of pathogens like bacteria, fungi, and several viruses and play an important role in inflammation and wound repair.
mBD3 peptide showed antimicrobial activity against Gram-negative bacteria S.Aureus and S.pyogenes and against Gram-positive bacteria like certain strains of P.Aeruginosa (MIC of 8 µg/mL) and E.coli (MIC of 16 µg/mL). Antimicrobial activity has also been demonstrated against C.Albicans.
The in vivo and in vitro efficiency of mBD3 against viruses like influenza was also shown. mBD3 can be interesting for therapeutic use.Amyloid beta (40-1)
Amyloid beta (Aβ) is a peptide fragment of the amyloid precursor protein, which is cleaved by β- and γ-secretases to form Aβ. It has been shown to be an activator of presynaptic ion channels and can bind to receptors such as the low density lipoprotein receptor related protein 1 (LRP1). Amyloid beta influences cell biology in many different ways. For example, it inhibits the growth of neurons and can induce apoptosis. In addition, this peptide can inhibit the activity of ion channels by binding to specific sites on their surface. Amyloid beta also binds to antibodies that are used for research purposes. Aβ40-1 is an antibody for research purposes only.Purezza:Min. 95%IGF1 V44M
IGF-1 V44M is a recombinant protein that is an activator of the insulin receptor. It has been developed as a research tool to study the function of the insulin receptor and is used in pharmacological and cell biology studies. IGF-1 V44M is a single amino acid substitution of Valine at position 44, which replaces Methionine. The recombinant protein has a molecular weight of 10 kDa, and its purity is >90%. IGF-1 V44M can be used to inhibit the activity of the insulin receptor by binding to it with high affinity.Purezza:Min. 95%Nucleocapsid biotinylated protein library
The Nucleocapsid Protein (N-protein), also called coronavirus nucleocapsid (N), is the most abundant protein in coronavirus. It is a structural protein that forms complexes with genomic RNA, interacts with the viral membrane protein during virion assembly and plays a critical role in enhancing the efficiency of virus transcription and assembly.
Plasminogen Heavy Tryptic Peptide Standard (4nmol)
For Protein Identification and QuantitationPurezza:Min. 95%Alpha-Conotoxin SI
CAS:Sourced from the marine snail, conus striatus, this synthetic cone snail toxin is a nicotinic acetylcholine receptor blocker. This product has disulfide bonds between Cys2-Cys7 and Cys3-Cys7.
Formula:C55H84N16O16S4Purezza:Min. 95%Peso molecolare:1,353.6 g/molApelin-36, human
CAS:Custom research peptide; min purity 95%.Formula:C184H297N69O43SPurezza:Min. 95%Peso molecolare:4,195.92 g/molVasoconstriction-Inhibiting Factor, human
Vasoconstriction-Inhibiting Factor, human (VIF) is a peptide that inhibits the activity of ATP-sensitive potassium channels. It has been shown to be an inhibitor of both P2X and P2Y purinergic receptors. VIF is a cell biology research tool that can be used as a high purity reagent for antibody production. The use of this factor in ion channels may lead to the discovery of new drugs for treating cardiovascular diseases.Formula:C163H256N42O67SPurezza:Min. 95%Peso molecolare:3,908.1 g/molAngiotensin (Human, 1-7)
CAS:Angiotensin (Human, 1-7) is a peptide hormone that is produced in the body by the renin-angiotensin system. This peptide hormone helps to regulate blood pressure and blood volume. Angiotensin (Human, 1-7) works by activating both receptors on cells, which causes vasoconstriction and stimulates the release of aldosterone from the adrenal gland. Angiotensin (Human, 1-7) can also stimulate various ion channels and cause vasoconstriction. The antibody against this peptide may be used as a research tool for studying its function in cell biology or as an inhibitor or activator in pharmacology.Formula:C41H62N12O11•CH3COOH•4H2OPurezza:Min. 95%Peso molecolare:1,031.11 g/molHuman Serum Albumin
Human Serum Albumin is a stable protein that binds to fatty acids and helps transport them in the circulatory system. It can also bind to other molecules, such as drugs, and help with the transport of these molecules in the bloodstream. The protein is composed of amino acids, which are linked together by peptide bonds. The human serum albumin molecule has four subunits that are connected by disulfide bonds. These subunits are called alpha (α), beta (β), gamma (γ), and delta (δ). Human serum albumin contains many hydrophobic amino acids, which make it soluble in lipids and water. This protein is an important part of energy metabolism because it accepts electrons from fatty acid oxidation and transfers them to electron acceptors such as oxygen or NADPH.Purezza:Min. 95%[D-Pro2,D-Trp7,9]-Substance P (1ea)
This product is a Substance P antagonist and is available in the Hydrochloride salt form. Substance P is a member of the tachykinin neuropeptide family which is produced in the central nervous system (CNS) and acts through its specific receptor neurokinin 1 receptor (NK-1R). NK-1R is present in neurons and on glial cell types. Substance P is involved in: pain perceptions as a neurotransmitter; gut motility; increased inflammation in the lungs, gastrointestinal tract and the skin and neuroinflammation. Interestingly the levels of Substance P are raised in inflammatory bowel diseases and through its involvement in cytokine release, it contributes to asthma pathology. These diverse selection of functions makes substance P a target for therapeutic research.Formula:C74H106N20O13S•3HCI•6H2OPurezza:Min. 95%Peso molecolare:1,733.3 g/molAnti ACTH (Rat) Serum
Anti ACTH (Rat) Serum is a research tool that can be used to study the biological effects of ACTH. This serum contains activated rat ACTH, which is a ligand and binds to the receptor and activates the cell. The anti-ACTH antibody is used to detect ACTH in blood and tissue samples. Anti-ACTH serum has been shown to inhibit ion channel activity, protein synthesis, and peptide binding. It also inhibits the binding of an antibody specific for rat ACTH.Purezza:Min. 95%LR3 IGF1 Human
LR3 IGF1 Human is a cytokine that is a member of the interleukin family. It is one of the two forms of human insulin-like growth factor 1 (IGF-1), which plays an important role in regulating cell growth and differentiation. LR3 IGF1 Human has been shown to stimulate the proliferation of various cells, such as lymphocytes and fibroblasts, in vitro. In addition, this cytokine has been shown to inhibit apoptosis induced by serum deprivation.Purezza:Min. 95%Anti Somatostatin (Human, Rat) Serum
Anti Somatostatin (Human, Rat) Serum is a research tool that can be used to activate or suppress the function of cells by binding to their receptors. This antibody binds to somatostatin receptors and blocks their ability to bind to the ligand. It is also used for the detection of ion channels in cell biology. Antibody against somatostatin can be used as an inhibitor in pharmacological studies.Purezza:Min. 95%Anti EGF, Human Serum
Anti-EGFR (Epidermal Growth Factor Receptor) is a monoclonal antibody that binds to the epidermal growth factor receptor (EGFR). The EGFR is a transmembrane tyrosine kinase receptor that plays an important role in cell proliferation, differentiation, and survival. Anti-EGFR can be used as a research tool for studying protein interactions, such as the interaction of peptides with receptors or ligands. It can also be used for pharmacological studies and can be used to isolate proteins from cells. This product is available in high purity, which means it has been purified by chromatography to have less than 0.1% other proteins than the product. This product is also available in a form of an antibody conjugate, which means that it has been linked to an antibody molecule that recognizes the target antigen specifically. Anti-EGFR is available in CAS No., which stands for Chemical Abstracts Service Number.
Purezza:Min. 95%MPS (NHS-3-Maleimidopropionate)
CAS:MPS is a compound that is used in peptide synthesis. It is a maleimidopropionate reagent that reacts with primary amines to form stable amides. MPS can be used as a building block for the synthesis of polymers, and it contains an N-hydroxysuccinimide ester group that can react with thiols to form stable disulfides. This product is available for purchase from Quanta BioDesign.Formula:C13H24O7SPurezza:Min. 95%Peso molecolare:324.39 g/molPolystyrene M NH2 (5 µm)
Polystyrene is a thermoplastic polymer that is used in the production of polystyrene resins, which are used as building blocks for peptide synthesis. New England Peptide offers a variety of polystyrene resin products including particle resins and Rapp Polymere resins. The particle size of the resin ranges from 5-100 µm. Polymers can be synthesized using various methods including solid-phase synthesis and solution phase synthesis, which both require polystyrene resins. This product is available with a variety of functionalities, such as amine, hydroxyl and carboxyl groups.
Purezza:Min. 95%SSSTAYMHLK* - SIL Dinutuximab signature peptide quantifier
Primary SIL peptide for Dinutuximab detection and quantification
Apelin-36 (Human, 1-16 Amide)
Apelin-36 is a peptide hormone that is derived from a larger precursor protein. It is a member of the apelin peptide family, which is involved in regulating cardiovascular and metabolic functions. Apelin-36 binds to a G protein-coupled receptor called APJ (apelin receptor), which is widely expressed in various tissues. The interaction between apelin-36 and APJ receptor leads to a range of physiological effects, such as cardiac contractility stimulation and blood pressure suppression as well as lowering body weight and improving glucose homeostasis. Research has shown that apelin-36 may have therapeutic potential in the treatment of cardiovascular diseases, such as hypertension and heart failure, as well as metabolic disorders, such as obesity and diabetes. Apelin-36 has also been implicated in other physiological processes, including inflammation, angiogenesis, and cancer progression. This product is available as a 0.1 mg vial.Formula:C74H117N27O20Purezza:Min. 95%Peso molecolare:1,704.9 g/molNeuroendocrine Regulatory Peptide-2 (Rat) (0.1mg)
This Neuroendocrine Regulatory Peptide- 2 (Rat) product can be used as an endogenous suppressor of vasopressin release and is available as a 0.1mg vial. The neuroendocrine regulatory peptide-2 (NERP2) is derived from VGF and it colocalizes with vasopressin in the hypothalamus and it has been found that NERPs prevent vasopressin release from the hypothalamus. Thus NERP2 is involved in body fluid homeostasis through modulating the release of vasopressin.Formula:C175H290N56O59Purezza:Min. 95%Peso molecolare:4,122.5 g/molIGHG1 MS Calibrator-4 (25nmol)
The IGHG1 MS Calibrator-4 is a tryptic peptide that is a product of the Ig gamma-1 chain C region. This peptide is used as a calibrator for mass spectrometry. The IGHG1 MS Calibrator-4 contains Biologically Active Peptides, which can be used to identify the presence of proteins in biological samples. The New England Peptide Company offers peptides for use in proteomics, such as the IGHG1 MS Calibrator-4.Purezza:Min. 95%Azido-dPEG®36-OH
Azido-dPEG®36-OH is a PEG polymer categorised as monofunctional (OH-PEG-X). Used as a linker, azido-dPEG®36-OH is used to attached PEG to proteins, peptides, oligonucleotides, nanoparticles and small molecules via pegylation, a bioconjugation technique.Formula:C57H101F4N3O26Purezza:Min. 95%Peso molecolare:1,320.41 g/molNeuropeptide RFRP-2 (101-112)
Neuropeptide: Neuropeptides are small signaling molecules produced and released by neurons engaged in many physiological functions. Indeed, neuropeptides act on neural substrates such as G protein-coupled receptors (GPCRs), tyrosine-kinase receptor, insuline-like peptides and also ion channels. Actions of Neuropeptides result in slow-onset, long-lasting modulation of synaptic transmission. Pro-FMRFamide-related neuropeptide VF: Pro-FMRFamide-related neuropeptide VF also called neuropeptide VF precursor are expressed in neurons in mediobasal hypothalamus. Neuropeptide VF precursor is a propeptide which is cleaved in three others peptide: Neuropeptide RFRP-1, RFRP-2 and RFRP-3. Neuropeptide RFRP-2 (101-112): Neuropeptide RFRP-2 (101-112) is very interesting because RFRP-2 shows no inhibitory activity and RFRP-2 sequence is absent in mouse and rat.Lipoamido-dPEG®24-TFP Ester
Lipoamido-dPEG®24-TFP Ester is a PEG molecule conjugated with a lipid moiety. Lipoamido-dPEG®24-TFP Ester, conjugated to this lipid constituent, is very important especially in drug delivery and vaccine development as it helps improve the stability and circulation time of lipid nanoparticles (LNPs) and liposomes.
Formula:C8H14O6Purezza:Min. 95%Peso molecolare:206.19 g/molZ-Leu-Leu-H aldehyde
Z-Leu-Leu-H aldehyde is a water soluble and non-toxic chemical compound that belongs to the class of heterocycles. It inhibits ion channels by binding to their receptor and also has a high affinity for ligand binding sites. Z-Leu-Leu-H aldehyde is used as a research tool in pharmacology, cell biology, and antibody production. It can be used to activate or inhibit the function of proteins in cells by acting as an agonist or antagonist, respectively. This chemical is also an inhibitor with high purity, which is suitable for use in protein crystallization experiments.Formula:C20H30N2O4Purezza:Min. 95%Peso molecolare:362.46 g/molAc-Abu-Tle-Leu-Gln-AMC
Ac-Abu-Tle-Leu-Gln-AMC is a peptide that activates the ion channels of ligand gated calcium channels. It is an inhibitor of the glycine receptor, which is a type of ligand gated ion channel. Ac-Abu-Tle-Leu-Gln-AMC binds to the agonist binding site and blocks the neurotransmitter glycine from activating the receptor. This peptide has been shown to be effective in inhibiting neuronal excitability in rodent models.Purezza:Min. 95%Gly-Leu
CAS:Gly-Leu is a cyclic peptide that was originally isolated from human serum. It has been shown to have antibiotic activity against bacteria such as Escherichia coli and Staphylococcus aureus. This drug also inhibits the enzyme activities of trifluoroacetic acid, sodium citrate, and calcium binding. Gly-Leu has been shown to have anti-tumour properties in vivo by inhibiting the growth of carcinoma cell lines and inducing apoptosis in these cells. It also has immunomodulatory effects on autoimmune diseases such as multiple sclerosis.Formula:C8H16N2O3Purezza:Min. 95%Peso molecolare:188.22 g/molT4 DNA Ligase (recombinant)
T4 DNA Ligase is a recombinant protein that catalyzes the formation of DNA molecules from complementary single-stranded DNA. T4 DNA Ligase is used as a research tool in cell biology and biochemistry to study the interactions between proteins and peptides. It is also used to produce recombinant proteins, such as antibodies. T4 DNA Ligase binds to its substrate by an ionic interaction with adenosine triphosphate (ATP) and to the complementary strand by hydrogen bonding. The enzyme cleaves the phosphate backbone of both strands at the junction point, forming two new phosphodiester bonds. This enzyme has been shown to bind to other proteins and peptides, such as receptor tyrosine kinases, which are involved in signal transduction pathways that regulate cell growth and differentiation.Purezza:Min. 95%[D-Pro4,Trp7,9]-Substance P (4-11)
Substance P (SP) is a neuropeptide that has been implicated in the transmission of pain and inflammation. It also regulates feeding behaviour and is a potent stimulator of gastric acid secretion. In addition, SP has been shown to be an antagonist for the insulin receptor. This peptide may therefore contribute to the development of diabetes mellitus type 2.Formula:C57H75N13O10S•CH3COOH•4H2OPurezza:Min. 95%Peso molecolare:1,266.51 g/molPeptide YY (Human)-EIA Kit (1ea)
Peptide YY (Human)-EIA Kit (1ea) is an EIA kit for the quantitative analysis of human peptide YY. Peptide YY is a neuropeptide with a role in the regulation of food intake and energy expenditure. The kit contains one vial each of peptide YY antiserum, peptide YY antibody, and standard reference material. The assay can be used to detect the level of peptide YY in tissue samples or cell culture supernatants.
Purezza:Min. 95%IGF1 Rat
IGF1 Rat is a recombinant IGF-1 receptor ligand that is a member of the insulin-like growth factor family. It activates the IGF-1 receptor and has been used as a research tool for studying protein interactions, such as those with G-protein coupled receptors and ion channels. The recombinant IGF-1 rat peptide is an excellent choice for pharmacological studies because it is highly purified and contains no contaminants.Purezza:Min. 95%NERP-1 - Neuroendocrine regulatory peptide 1
NERP-1 (Human) modulates body fluid homeostasis and suppresses vasopressin release
1-Deoxyfructosyl-Val-His-Leu-Thr-Pro-Glu
CAS:1-Deoxyfructosyl-Val-His-Leu-Thr-Pro-Glu is a peptide that binds to ion channels in the cell membrane. It has been shown to activate some receptors and inhibit others, which may be useful for research. The peptide also has an antibody against it, so its purity can be confirmed.Formula:C37H60N8O15Purezza:Min. 95%Peso molecolare:856.92 g/molNH2-dPEG®4-Glu(OH)-NH-m-dPEG®24
NH2-dPEG®4-Glu(OH)-NH-m-dPEG®24 is a peptide containing polyethylene glycol (PEG) as spacer to alter their pharmacokinetic properties and pharmodynamics.Formula:C65H129N3O32Purezza:Min. 95%Peso molecolare:1,464.72 g/molm-dPEG®48-CO(CH2)3-Acid
m-dPEG®48-CO(CH2)3-Acid is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. m-dPEG®48-CO(CH2)3-Acid is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.Formula:C102H203NO51Purezza:Min. 95%Peso molecolare:2,259.7 g/molPSA (53-92), Human Antiserum
PSA (53-92) is a peptide with the sequence of Gly-Gly-Ala-Pro-Lys. It is an activator of ion channels and can be used as a research tool in pharmacology, cell biology, and biochemistry. PSA (53-92) has been shown to be an inhibitor of the ligand binding domain of the human erythrocyte receptor for pyruvate dehydrogenase complex. The antibody that recognizes PSA (53-92) is also available.Purezza:Min. 95%Anti GRP (Porcine) Serum
GRP is a member of the G protein-coupled receptor family. GRP is an endogenous ligand for the GPCR, with binding affinity to GRP receptors. Activation of GRP receptors results in inhibition of cAMP production and activation of K+ channels. Anti-GRP serum is a research tool that can be used to identify and characterize GRP receptors by blocking their ability to bind endogenous ligands. This inhibitor has been shown to inhibit peptides that are inhibitors for ion channels, such as the nicotinic acetylcholine receptor and the glycine receptor. The anti-GRP serum also binds to antibodies raised against the peptide sequence of GRP, which may be used to identify these proteins in immunoblots or Western blots.Purezza:Min. 95%Chlorotoxin
CAS:Chlorotoxin is an ion channel activator that is characterized by its high purity and affinity. It has been shown to bind to the acetylcholine receptor in the brain, which leads to increased levels of acetylcholine at the synapse and subsequent activation of postsynaptic neurons. Chlorotoxin also inhibits potassium channels, leading to hyperpolarization of cells and a decrease in neuronal activity. The peptide is used as a research tool for cell biology and pharmacology studies.Formula:C158H249N53O47S11Purezza:Min. 95%Peso molecolare:3,995.7 g/molACE2 peptide library
Angiotensin-converting enzyme 2 (ACE2) is an enzyme involved in the cardiovascular system by decreasing arterial pressure by catalyzing the conversion of angiotensin II to angiotensin (1-7). Angiotensin II is a vasoconstrictor and angiotensin (1-7) is a vasodilatator. This effect makes ACE2 a therapeutic target for cardiovascular disease.
C Reactive Protein Heavy Tryptic Peptide Standard (4nmol)
C Reactive Protein Heavy Tryptic Peptide Standard for protein identification and quantitation studies. C-reactive protein is an acute phase protein present in blood plasma and is produced by the liver. During inflammation levels of c-reactive protein increase and therefore it can be a useful protein to indicate an infection is present.Purezza:Min. 95%Biotin-dPEG®23-Lipoamide
Biotin-dPEG®23-Lipoamide is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. Biotin-dPEG®23-Lipoamide is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.Formula:C66H126N4O26S3Purezza:Min. 95%Peso molecolare:1,487.92 g/mol
![[D-Ala2,Met5]-Enkephalin](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F3D%2Fthumb-webp%2FPEK-4116.webp&w=3840&q=75)
![[Asu1,6,Arg8]-Vasotocin](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F3D%2Fthumb-webp%2FPVP-4027-V.webp&w=3840&q=75)
![[D-Pro2,D-Trp7,9]-Substance P (1ea)](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F3D%2Fthumb-webp%2FPSP-4113.webp&w=3840&q=75)
![[D-Pro4,Trp7,9]-Substance P (4-11)](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F3D%2Fthumb-webp%2FPSP-4114.webp&w=3840&q=75)
