Peptidi

A synthetic scorpion toxin consisting of disulfide bonds between Cys3-Cys17, Cys10-Cys21, and Cys16-Cys32. It can be used as an activator of Ca2+ Release Channels/Ryanodine Receptors. It is important to understand the functions of Ryanodine receptors as they mediate Ca2+ release from intracellular reticular stores and this is imperative for signalling processes, namely muscle excitation-contraction coupling. If skeletal and cardiac Ryanodine receptor genes are mutated diseases such as congenital myopathy and metabolic disorders occur. Therefore Imperatoxin A is useful in investigating these diseases. This product is avaiable as a 0.1mg vial.

Antiproliferative factor Sialoglycopeptide is a research tool that has been shown to activate the immune system. It has been used as a vaccine carrier and in immunotherapy. Antiproliferative factor Sialoglycopeptide binds to the C-type lectin receptor on erythrocytes, triggering an antibody response. This protein also interacts with ion channels, such as Ca2+ channels, and inhibits protein synthesis by inhibiting the tyrosine kinase activity of protein kinase A (PKA). Antiproliferative factor Sialoglycopeptide is a peptide that is active against many types of cancer cells and has been shown to inhibit tumor growth in mice. The CAS number for Antiproliferative Factor Sialoglycopeptide is 12074-48-2.

NHS-dPEG®4-( m-dPEG®12)3-Ester is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. NHS-dPEG®4-( m-dPEG®12)3-Ester is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.

DBCO-dPEG®12-TFP Ester is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. DBCO-dPEG®12-TFP Ester is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.

Bombesin is a small peptide that was first isolated from the skin of a frog, Bombina bombina, with homologs later found to be present in mammalian tissues, including the brain and gastrointestinal tract. It is a member of the bombesin-like peptide family, which includes several related peptides such as gastrin-releasing peptide (GRP) and neuromedin B.
Bombesin acts as a neuromodulator and regulates various physiological functions, including gastrointestinal motility and stimulation of gastrin release from G cells. It also plays a role in the regulation of cardiovascular function and neurotransmitter release. In addition, bombesin has been shown to stimulate the growth and proliferation of certain types of cancer cells, including prostate and lung cancer cells, through its interaction with bombesin receptors. It may therefore be used as a potential biomarker for certain cancers.
This product is available as a 0.5mg vial.

Fmoc-N-Amido-dPEG®3-Acid is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. Fmoc-N-Amido-dPEG®3-Acid is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.

This product has disulfide Bonds between Cys1-Cys15 and Cys3-Cys11, is sourced from: Porcine, 1-39 and is available as a 0.5mg vial. Big Endothelin-1 (Porcine, 1-39) is a precursor peptide of the vasoconstrictor Endothelin-1 (ET-1). ET-1 exhibits vasoconstrictive properties and is an activator of endothelin G-protein coupled receptors. Furthermore ET-1 is produced when inflammation, vascular stress or hypoxia occurs. In vivo Big Endothelin-1 has a greater half life compared to ET-1 and therefore makes it useful to study secretory activity in the endothelial system.
Overall Big Endothelin-1 (Porcine, 1-39) can be used as a research tool for studying protein interactions, receptor activation and function, and ligand binding. This peptide is also used in pharmacology to study the effects of therapeutic agents on receptor activity and expression.

Des-Arg9-[Leu8]-bradykinin is a bradykinin receptor activator. This peptide can be used as a research tool to study the relationship between peptides and ion channels in cell biology, and to assess the effects of inhibitors on protein interactions. Des-Arg9-[Leu8]-bradykinin has shown inhibitory activity against a number of ligand binding receptors, including the beta-adrenergic receptor, angiotensin II receptor, and acetylcholine muscarinic receptor. The affinity of this peptide for different receptors is dependent on its position within the molecule.

Gly-Phe-NH2 is an amino acid that can be used as a research tool in the study of protein interactions, receptor activation, and ion channels. It has been shown to activate ligands such as peptides and antibodies. This compound also inhibits ligands in the cell biology field. Gly-Phe-NH2• AcOH is a white powder with a purity of 99%.

m-dPEG®12-MAL is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. m-dPEG®12-MAL is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.

NPY is a peptide that belongs to the family of neuropeptides. It is an activator of G-protein coupled receptors, which are proteins found on the surface of cells. NPY binds to these receptors and triggers a signal transduction cascade that leads to increased activity in ion channels. This results in an increase in the permeability of the membrane and the influx of calcium ions into cells, which can cause cell death or inhibition of cell growth. NPY has been shown to be involved in many physiological processes, including regulation of food intake, body weight, water balance, reproduction, and immune function. NPY has also been shown to inhibit receptor binding by antibodies.

NPY (Human, Rat) is a peptide that belongs to the family of neuropeptides. It is a central neurotransmitter and neuromodulator in the brain and has an important role in the regulation of many physiological processes, including feeding behavior, body weight, blood pressure, stress responses and reproduction. NPY (Human, Rat) is used as a research tool for studying ion channels and receptor interactions. This product is also used to develop antibodies that can be used as a research tool or diagnostic reagent. NPY (Human, Rat) is not active when taken orally; it must be injected into the body.

Amino-dPEG® t-Butyl Ester is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. Amino-dPEG® t-Butyl Ester is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.

Dnp-Pro-Gln-Gly is a synthetic peptide that can be used as an artificial substrate in protease assays. It is activated by the addition of trypsin and catalyzes hydrolysis of peptide bonds at the C-terminus of the proline residue. The chromatographic profile of Dnp-Pro-Gln-Gly on a Zorbax 300SBX column shows two peaks, with retention times of 8.2 minutes and 9.4 minutes. In tissue culture experiments, Dnp-Pro-Gln-Gly was found to enhance the activity of matrix metalloproteinases and collagenase. The optimum pH for Dnp-Pro-Gln-Gly is 5.5, which is near the pH optimum for most mammalian tissues and organs.

A synthetic voltage-dependent K+ channel blocker derived from bee venom. This product is sourced from the Honeybee, Apis mellifera and has disulfide bonds between Cys3-Cys15 and Cys5-Cys19.
Available as a 0.5mg vial.

MAL-dPEG®4-t-boc-Hydrazide is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. MAL-dPEG®4-t-boc-Hydrazide is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.

t-boc-N-Amido-dPEG®24-Acid is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. t-boc-N-Amido-dPEG®24-Acid is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.

Azido-dPEG®3-Amine is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. Azido-dPEG®3-Amine is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.

Huwentoxin XVI is a synthetic molecule that inhibits the transmission of pain signals. It does this by inhibiting the release of neurotransmitters from dorsal root ganglia cells in the spinal cord. Huwentoxin XVI has been shown to inhibit the cancer-associated inflammatory response, which may be due to its ability to inhibit chronic pain. In addition, Huwentoxin XVI has been shown to have an inhibitory effect on adipose tissue and is thought to be a potential treatment for obesity-associated chronic pain. Huwentoxin XVI also blocks A-type potassium channels, which are responsible for neuronal transmission and are found in neurons and glial cells in the dorsal root ganglia. This inhibition can lead to neuropathic pain or chronic pain caused by nerve damage.

Antipain is a proteolytic enzyme that hydrolyzes peptide bonds in proteins. It is a member of the papain family of proteases and has been shown to activate peptides and inhibit ion channels, both of which are important for cell biology research. Antipain, an inhibitor of protein synthesis, is also used as a research tool in cell biology and biochemistry.

Vasotocin is a peptide hormone that is found in the hypothalamus. It is an activator of the vasopressin receptor and has been shown to activate ion channels and inhibit the release of neurotransmitters. Vasotocin also binds to a specific receptor on the surface of cells, which may be involved in cell biology and may have applications in pharmacology and antibody research. Vasotocin is purified from pig pituitary glands.

CGRP (Human, 8-37) is a peptide derived from the calcitonin gene-related peptide (CGRP) that is found in the nervous system and other tissues in humans. It is a truncated form of the full-length CGRP peptide, consisting of the last 30 amino acids of the CGRP sequence (amino acids 8-37).
CGRP is a potent vasodilator and plays a key role in regulating blood flow and blood pressure. It is also involved in pain perception, inflammation, and neurogenic inflammation. CGRP (Human, 8-37) is an antagonist of CGRP, meaning that it binds to the CGRP receptor without activating it, thereby blocking the effects of CGRP.
CGRP (Human, 8-37) has been used as a research tool to study the physiological and pathological roles of CGRP in various tissues and diseases, such as migraine headaches, cardiovascular diseases, and inflammatory disorders. It has also been investigated as a potential therapeutic agent for these conditions, as well as for the treatment of pain and other neurological disorders.
This product is available as a 0.5mg vial.

NHS-dPEG®12 Biotin is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. NHS-dPEG®12 Biotin is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.

SPDP-dPEG®12-Acid is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. SPDP-dPEG®12-Acid is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.

Endothelin-2 (ET-2) and Endothelin-1 (ET-1) differ from each other by 2 amino acids and have affinity for ETA and ETB G-protein coupled receptors which are found in a variety of tissues, including lungs, heart, kidneys, uterus and vasculature. It is believed that ET-2 is a potent vasoconstrictor and may play a role in cancer, immunology and heart failure.
This product has disulfide bonds between Cys1-Cys and Cys3-Cys11, is of Canine source and is available as a 0.1mg vial.

CCK-33 is a peptide that was originally isolated from porcine brain. It has been shown to be an activator of ion channels, a ligand for receptors, and an inhibitor of protein interactions. CCK-33 is also a pharmacological tool that can be used to study the role of ion channels in cellular processes such as neurotransmission and cell proliferation. CCK-33 is a receptor antagonist, which means it binds to the receptor and blocks the binding site. This prevents other compounds from binding to the receptor and activating it, thereby blocking its effects.

A synthetic peptide for use as a blocking control in assays to test for specificity of RHOBTB1 antibody, catalog no. 70R-5842

A synthetic peptide for use as a blocking control in assays to test for specificity of ALDH3A2 antibody, catalog no. 70R-7118

A synthetic peptide for use as a blocking control in assays to test for specificity of ZNF609 antibody, catalog no. 20R-1068

A synthetic peptide for use as a blocking control in assays to test for specificity of Tead4 antibody, catalog no. 70R-7987

A synthetic peptide for use as a blocking control in assays to test for specificity of QRSL1 antibody, catalog no. 70R-3579

A synthetic peptide for use as a blocking control in assays to test for specificity of IGFALS antibody, catalog no. 70R-6058

A synthetic peptide for use as a blocking control in assays to test for specificity of CTSS antibody, catalog no. 70R-10207

A synthetic peptide for use as a blocking control in assays to test for specificity of Tcea3 antibody, catalog no. 70R-8706

A synthetic peptide for use as a blocking control in assays to test for specificity of LOC652825 antibody, catalog no. 70R-2983

Z-Gly-Pro-Arg-AMC is a synthetic peptide that can inhibit the activity of various enzymes. It has been shown to be an inhibitor of protein interactions, activator of ligand, and receptor. This peptide is used as a research tool in cell biology and pharmacology studies. Z-Gly-Pro-Arg-AMC is also used in high purity applications (e.g., ion channels) and antibody production.

A synthetic peptide for use as a blocking control in assays to test for specificity of CCBE1 antibody, catalog no. 70R-4000

A synthetic peptide for use as a blocking control in assays to test for specificity of ZDHHC13 antibody, catalog no. 70R-1661

A synthetic peptide for use as a blocking control in assays to test for specificity of Pou4f3 antibody, catalog no. 70R-7967

A synthetic peptide for use as a blocking control in assays to test for specificity of HABP2 antibody, catalog no. 70R-6071

A synthetic peptide for use as a blocking control in assays to test for specificity of NCKIPSD antibody, catalog no. 70R-9799

A synthetic peptide for use as a blocking control in assays to test for specificity of HIF3A antibody, catalog no. 20R-1240

A synthetic peptide for use as a blocking control in assays to test for specificity of TERF2 antibody, catalog no. 20R-1063

A synthetic peptide for use as a blocking control in assays to test for specificity of DAPK1 antibody, catalog no. 70R-5933

A synthetic peptide for use as a blocking control in assays to test for specificity of MOSPD3 antibody, catalog no. 70R-1823

A synthetic peptide for use as a blocking control in assays to test for specificity of KLHL15 antibody, catalog no. 70R-2834

A synthetic peptide for use as a blocking control in assays to test for specificity of OR6C75 antibody, catalog no. 70R-6259

A synthetic peptide for use as a blocking control in assays to test for specificity of PITPNM1 antibody, catalog no. 70R-9888

A synthetic peptide for use as a blocking control in assays to test for specificity of SLC25A34 antibody, catalog no. 70R-6515

A synthetic peptide for use as a blocking control in assays to test for specificity of VASP antibody, catalog no. 70R-10267

A synthetic peptide for use as a blocking control in assays to test for specificity of ASS antibody, catalog no. 70R-1134

A synthetic peptide for use as a blocking control in assays to test for specificity of SEC14L4 antibody, catalog no. 70R-3716

A synthetic peptide for use as a blocking control in assays to test for specificity of BSCL2 antibody, catalog no. 70R-8856

A synthetic peptide for use as a blocking control in assays to test for specificity of ROPN1L antibody, catalog no. 70R-10111

A synthetic peptide for use as a blocking control in assays to test for specificity of POGZ antibody, catalog no. 70R-7962

A synthetic peptide for use as a blocking control in assays to test for specificity of ST3GAL1 antibody, catalog no. 70R-7382

Anti-Secretin (Rat) Serum is a high purity antibody that can be used as a research tool for studying the interactions between proteins. It is suitable for use in immunoassays, such as ELISA and Western blotting. Anti-Secretin (Rat) Serum has been shown to inhibit the activation of ion channels and receptors, as well as protein synthesis and ligand binding.

A synthetic peptide for use as a blocking control in assays to test for specificity of ZNF423 antibody, catalog no. 70R-8312

A synthetic peptide for use as a blocking control in assays to test for specificity of MASTL antibody, catalog no. 70R-10147

Insulin is a hormone that regulates the metabolism of carbohydrates and fats. It is produced by beta cells in the pancreas and prevents hyperglycemia. Insulin binds to insulin-specific receptors on the cell membrane, resulting in increased glucose uptake by muscle and fat cells. Monoclonal Mouse Anti-Human Insulin is an antibody that binds to human insulin and blocks its action, thereby lowering blood sugar levels. This antibody was immunised with human insulin and purified from mouse spleen cells. The antibody has been shown to block glycogen synthesis and fatty acid synthesis in vitro. Monoclonal Mouse Anti-Human Insulin also has a high binding affinity for erythrocytes and penetrates these cells easily. When injected into humans, this antibody binds to the erythrocytes in the blood stream and prevents their passage through capillary walls into tissues such as muscle or fat cells, thereby preventing glycolysis (the conversion of glucose into energy) in those tissues

A synthetic peptide for use as a blocking control in assays to test for specificity of CLIon Channel5 antibody, catalog no. 70R-1502

A synthetic peptide for use as a blocking control in assays to test for specificity of MELK antibody, catalog no. 70R-3472

A synthetic peptide for use as a blocking control in assays to test for specificity of GRIK2 antibody, catalog no. 70R-5200

A synthetic peptide for use as a blocking control in assays to test for specificity of ZGPAT antibody, catalog no. 70R-4430

A synthetic peptide for use as a blocking control in assays to test for specificity of GJB2 antibody, catalog no. 70R-1685

A synthetic peptide for use as a blocking control in assays to test for specificity of ZNF280A antibody, catalog no. 70R-8983

A synthetic peptide for use as a blocking control in assays to test for specificity of ABCC8 antibody, catalog no. 70R-6686

A synthetic peptide for use as a blocking control in assays to test for specificity of TRIM72 antibody, catalog no. 70R-2774

A synthetic peptide for use as a blocking control in assays to test for specificity of PTX3 antibody, catalog no. 70R-5923

A synthetic peptide for use as a blocking control in assays to test for specificity of IMMP2L antibody, catalog no. 70R-10109

A synthetic peptide for use as a blocking control in assays to test for specificity of FBLN1 antibody, catalog no. 70R-5356

A synthetic peptide for use as a blocking control in assays to test for specificity of SNTG1 antibody, catalog no. 70R-3733

A synthetic peptide for use as a blocking control in assays to test for specificity of TBC1D14 antibody, catalog no. 70R-4318

A synthetic peptide for use as a blocking control in assays to test for specificity of TFR2 antibody, catalog no. 70R-6697

A synthetic peptide for use as a blocking control in assays to test for specificity of IMP5 antibody, catalog no. 70R-7517

A synthetic peptide for use as a blocking control in assays to test for specificity of ELOVL7 antibody, catalog no. 70R-1788

A synthetic peptide for use as a blocking control in assays to test for specificity of C15orf15 antibody, catalog no. 70R-3901

A synthetic peptide for use as a blocking control in assays to test for specificity of DCTD antibody, catalog no. 70R-4083

A synthetic peptide for use as a blocking control in assays to test for specificity of EXOC3 antibody, catalog no. 70R-2856

A synthetic peptide for use as a blocking control in assays to test for specificity of CXCL16 antibody, catalog no. 70R-6007

A synthetic peptide for use as a blocking control in assays to test for specificity of MUC3B antibody, catalog no. 70R-6348

A synthetic peptide for use as a blocking control in assays to test for specificity of TCEAL8 antibody, catalog no. 70R-8874

A synthetic peptide for use as a blocking control in assays to test for specificity of KPNA5 antibody, catalog no. 70R-2092

A synthetic peptide for use as a blocking control in assays to test for specificity of KCNAB2 antibody, catalog no. 70R-5040

A synthetic peptide for use as a blocking control in assays to test for specificity of CXADR antibody, catalog no. 70R-6982

A synthetic peptide for use as a blocking control in assays to test for specificity of PEX10 antibody, catalog no. 70R-6974

A synthetic peptide for use as a blocking control in assays to test for specificity of FAM82A antibody, catalog no. 70R-3583

A synthetic peptide for use as a blocking control in assays to test for specificity of EGLN3 antibody, catalog no. 70R-2564

A synthetic peptide for use as a blocking control in assays to test for specificity of AK7 antibody, catalog no. 70R-10381

A synthetic peptide for use as a blocking control in assays to test for specificity of PKLR antibody, catalog no. 70R-1230

A synthetic peptide for use as a blocking control in assays to test for specificity of UPF3B antibody, catalog no. 70R-1348

A synthetic peptide for use as a blocking control in assays to test for specificity of RBBP5 antibody, catalog no. 70R-8021

A synthetic peptide for use as a blocking control in assays to test for specificity of CACNG4 antibody, catalog no. 70R-1535

A synthetic peptide for use as a blocking control in assays to test for specificity of TBCD antibody, catalog no. 70R-10390

A synthetic peptide for use as a blocking control in assays to test for specificity of ADHFE1 antibody, catalog no. 70R-3710