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Peptidi

Peptidi

I peptidi sono catene corte di amminoacidi legate da legami peptidici, che svolgono ruoli chiave come molecole biologiche importanti nei processi cellulari. Funzionano come ormoni, neurotrasmettitori e molecole di segnalazione, e sono ampiamente utilizzati in applicazioni terapeutiche e diagnostiche. I peptidi sono anche cruciali nella ricerca per lo studio delle interazioni proteiche, delle attività enzimatiche e dei percorsi di segnalazione cellulare. Presso CymitQuimica, offriamo una vasta selezione di peptidi di alta qualità per supportare le vostre esigenze di ricerca e sviluppo in biotecnologia e farmacologia.

Sottocategorie di "Peptidi"

Trovati 29890 prodotti di "Peptidi"

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  • Click MitP


    MitP cell penetrating peptide labelled at the N-terminus with an alkyne attachment for ease of reaction with an opposite Click reactive partner (azide).
    Colore e forma:Powder
    Peso molecolare:1,601.1 g/mol

    Ref: 3D-CRB1000124

    1mg
    282,00€
    500µg
    206,00€
  • Leptin (116-130) Mouse


    Leptin is a member of the adipocytokines or adipokines group of cytokines which are primarily produced in adipose tissue. Leptin is both a hormone involved in multiple endocrine functions, bone metabolism and thermoregulation, and a cytokine that promotes inflammatory responses. People with obesity have elevated levels of leptin. This contributes to the state of low-grade inflammation that makes those individuals more likely to develop cardiovascular diseases, type II diabetes, degenerative disease and autoimmune disease. Reduced levels of leptin, found in malnourished individuals, has been linked to an increased risk of infection and reduced cell-mediated immunity.Leptin binds to leptin receptors (ObRs), of which there are at least six isoforms (ObRa, ObRb, ObRc, ObRd, ObRe, and ObRf). This fragment of leptin has been shown to restrict weight gain and food intake in female mice lacking active leptin.
    Colore e forma:Powder
    Peso molecolare:1,559.8 g/mol

    Ref: 3D-CRB1000467

    1mg
    282,00€
    500µg
    206,00€
  • Secretin (rat)

    CAS:
    Secretin is a gastrointestinal hormone secreted by S cells in the small intestine, targeting G-protein coupled secretin receptors in numerous cell types. Secretin is synthesised from the preprohormone pro-secretin and is involved in regulating gastric acid and bicarbonate ion secretion in the duodenum and regulating water homeostasis. During glucose intake, secretin stimulates the pancreas to release insulin.Secretin has clinical relevance as a method to detect gastrin-producing tumours. Administration of exogenous secretin to the duodenum for secretin stimulation test to occur. Secretin can also be used to detect pancreatic insufficiencies via s administration during endoscopic retrograde cholangiopancreatography (ERCP). This allows the detection of inflammatory and neoplastic conditions of the pancreas.Secretin plays a different role in the central nervous system, such that in secretin deficient mice, synaptic plasticity and hippocampal synaptic activity are altered. Thus, secretin can be categorised as a neuropeptide.
    Formula:C129H216N42O42
    Peso molecolare:3,027.36 g/mol

    Ref: 3D-CRB1000722

    1mg
    282,00€
    500µg
    206,00€
  • Flagellin 22 (flg22)


    Flagellin is a structural protein which forms the major portion of bacterial flagellar filaments. The N- and C-terminals of flagellin are highly conserved regions, whereas the central core can vary greatly between bacterial species. Flagellin 22 (flg22) is the stretch of amino acids most conserved across bacterial species and is located towards the N-terminal of the flagellin protein.Flg22 is a potent elicitor of plant immune responses and is recognised in plants by the membrane bound leucine-rich repeat-receptor kinase FLAGELLIN SENSITIVE 2 (FLS2). Flg22 induces defence gene expression to trigger both local and systemic immune responses and is thus widely used in plant defence studies.
    Colore e forma:Powder
    Peso molecolare:2,272.48 g/mol

    Ref: 3D-CRB1000331

    1mg
    282,00€
    5mg
    891,00€
    10mg
    1.518,00€
    500µg
    206,00€
  • EC dipeptide


    EC-acid has a formal charge of 0 and a range of biological and chemical uses. CE-acid is also available in our catalogue.
    Peso molecolare:250.1 g/mol

    Ref: 3D-CRB1001692

    1mg
    282,00€
    500µg
    206,00€
  • Biotin-Histone H3 (14-34) pT22 K23Me3


    H3 is a core component of the nucleosome, functioning in DNA compaction and availability to transcription machinery. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodelling. Similar to the other core histone, H3 has a globular domain and a flexible N-terminal domain, 'histone tail' which can undergo modifications such as acetylation, methylation, phosphorylation and ubiquitination. There is a wealth of data recording these modifications but understanding their significance is not as clear. In Caenorhabditis elegans H3K23me3 can be induced by exogenous dsRNA and this modification can persist for four generations after the dsRNA exposure has been stopped. H3K23me3 is enriched in C. elegans heterochromatic regions, the histone methyltransferase SET-32, methylates H3K23 in vitro.A 20-mer fragment of the N terminal histone tail is provided here with threonine 22 phosphorylated and lysine 23 tri-methylated (pT22 K23Me3) with an N terminal biotin label attached. The biotin label should allow for easy use in detection by fluorescence microscopy, ELISA or western blots. Alternatively, it can be purified for protein-protein interactions with the appropriate affinity purification protocol.

    Colore e forma:Powder
    Peso molecolare:2,456.3 g/mol

    Ref: 3D-CRB1000344

    1mg
    470,00€
    500µg
    386,00€
  • Bombesin


    Bombesin was originally isolated from the skin of the european fire-bellied toad (Bombina bombina) and has two known homologues Neuromedin B (NMB) and gastrin-releasing peptide (GRP).Bombesin-like peptides are involved in many physiological functions including: regulation of food intake- anxiety and fear-related behaviour, thermoregulation, stress response, learning and memory and in the stimulation of smooth muscle contraction. Bombesin is also a tumour marker for small cell carcinoma in the lung, gastric cancer, pancreatic cancer, and neuroblastoma.The receptors for these two peptides are known as bombesin receptor type 1 (BB1 also known as NMB receptor) and bombesin receptor type 2 (BB2 also known as GRP receptor). Bombesin shows high affinity to both of these receptor subtypes. These bombesin-like peptides and their receptors are widely distributed in the central nervous system (CNS) and gastrointestinal (GI) tract.This peptide contains an N-terminal pyroglutamyl to prevent the intramolecular cyclisation of the N-terminal of glutamine to N-pyroglutamate (pGlu).

    Peso molecolare:1,618.8 g/mol

    Ref: 3D-CRB1000583

    1mg
    282,00€
    500µg
    206,00€
  • XL 13m


    Inhibits the epigenetic reader YEATS domain of the Eleven-nineteen leukemia (ENL) protein and perturbs the recruitment of ENL onto chromatin. Induces downregulation of a set of genes that are essential for leukemogenesis and leukaemia maintenance.
    Peso molecolare:509.3 g/mol

    Ref: 3D-CRB1001368

    1mg
    282,00€
    500µg
    206,00€
  • Xenin


    Leptin and melanocortin are well characterised for their roles in energy balance and the regulation of feeding. However, xenin was subsequently isolated from human gastric mucosa and identified as a gastrointestinal peptide hormone. Evidence shows xenin plasma levels rise after meals while administration of xenin leads to feelings of satiation. Unfortunately, the mechanism of xenin regulation on food uptake is still not fully understood. Work has shown xenin negatively effects food intake by a dose dependent manner, the hypothalamus seems to have a key role in this. Furthermore, the signally pathways activated by xenin is independent of those used by leptin or melanocortins. Further work with xenin could provide vital answers to the inhibitory mechanism of this gastrointestinal hormone. It would provide more data to help tackle the ongoing obesity crisis and rise in the number of diabetic patients.
    Colore e forma:Powder
    Peso molecolare:2,969.7 g/mol

    Ref: 3D-CRB1001419

    1mg
    282,00€
    500µg
    206,00€
  • Nangibotide


    Nangibotide, also referred as LR12, is an antagonist of triggering receptor expressed on myeloid cells (TREM)-1, and was derived from residues 94 to 105 of TREM-like transcript-1 (TLT-1).TREM-1 plays a crucial role in the onset of sepsis by amplifying the host immune response. TLT-1- and TLT-1-derived peptides therefore exhibit anti-inflammatory properties by dampening TREM-1 signalling.  LR12 blocks TREM-1 by binding to the TREM-1 ligand and provides protective effects during sepsis such as inhibiting hyper-responsiveness, organ damage, and death, without causing deleterious effects. The protective effects of modulating TREM-1 signalling are also evident in other models of inflammation such as: pancreatitis- haemorrhagic shock- inflammatory bowel diseases and inflammatory arthritis.
    Colore e forma:Powder
    Peso molecolare:1,342.5 g/mol

    Ref: 3D-CRB1001271

    1mg
    282,00€
    5mg
    633,00€
    500µg
    206,00€
  • Syntide 2


    Syntide-2 is a substrate peptide which was specifically designed to be homologous to site 2 in glycogen synthase. Syntide-2 is therefore phosphorylated by Ca2+ calmodulin-dependent protein kinase II as well as other calcium dependant kinases and protein kinase C. Synthase-2 can also be phosphorylated by CAMP-dependent protein kinase and to a lesser extent- phosphorylase kinase, but not by myosin light chain kinase.

    Colore e forma:Powder
    Peso molecolare:1,506.9 g/mol

    Ref: 3D-CRB1000602

    1mg
    282,00€
    500µg
    206,00€
  • SARS-CoV-2 Membrane protein (172-188)


    SARS-CoV-2 Membrane protein (172-188)

    Colore e forma:Powder
    Peso molecolare:1,900 g/mol

    Ref: 3D-CRB1001838

    1mg
    282,00€
    500µg
    206,00€
  • TfR targeting sequence


    Binds to human transferrin receptor (TfR). This 12-amino acid peptide does not compete with transferrin for receptor binding and is able to internalise into TfR expressing cells.

    Peso molecolare:1,490.73 g/mol

    Ref: 3D-CRB1000196

    1mg
    282,00€
    500µg
    206,00€
  • SAMS peptide


    SAMS peptide was originally designed as a selective substrate for mammalian 5' adenosine monophosphate-activated protein kinase (AMPK) for use in kinase assays. However it is also able to be phosphorylated by the yeast AMP homologue- sucrose non-fermenting 1 kinase (SNF1) and SNF1-related kinases (SnRK1) in plants.The conserved family of kinases containing SnRK1, SNF1 and AMPK plays an important role in regulating cellular energy homeostasis.

    Colore e forma:Powder
    Peso molecolare:1,779.15 g/mol

    Ref: 3D-CRB1000209

    1mg
    282,00€
    500µg
    206,00€
  • [5-FAM]-beta-Amyloid (1-15) Human


    Fluorescein labelled amyloid β 1-15 (Aβ1-15 ). Aβ1-15 is one of many short Aβ species found in vivo and is formed by the cleavage of Aβ precursor protein by β- and alpha-secretase.Amyloid β-protein (Aβ) has been identified as the key subunit of the extracellular plaques found in the brains of patients with Alzheimer's disease (AD) and Down's syndrome (DS). Aβ has therefore been extensively studied as a potential target for treatment of AD.Aβ is formed from the cleavage of the large, transmembrane protein- APP (amyloid precursor protein). Cleavage of APP by β- and then γ-secretases results in the formation of Aβ. Aβ can aggregate to produce amyloid-β oligomers, which are thought to be highly neurotoxic. Over time Aβ can further aggregate to produce the characteristic senile plaques present in AD and DS. Aβ can be degraded by enzymes such as neprilysin, insulin degrading enzyme or endothelin converting enzyme. At physiological levels Aβ may be involved in controlling synaptic activity and neuronal survival.Fluorescein (FAM) is a hugely popular fluorescent tag due to its excellent fluorescence quantum yield and relatively high absorptivity as well as being highly water soluble.
    Peso molecolare:2,183.8 g/mol

    Ref: 3D-CRB1100839

    1mg
    386,00€
    100µg
    206,00€
    500µg
    282,00€
  • Histone H2A (1-20)


    The histone H2A residues 1-20 are derived from histone 2A (H2A) which is one of the four core his-tones (H2A, H2B, H3 and H4) fundamental in compacting eukaryotic DNA into a structure known as the nucleosome. The nucleosome arises when 147 base pairs of DNA wrap around a H3-H4 tetramer and two H2A-H2B dimers, forming the histone octamer core.At the site of DNA entry on the outer nucleosome, the C-terminus of H2A is present and is able to interact with linker histones or other factors. This allows for variation and changes in nucleosome stability to occur. Furthermore Histone H2A has histone variants such as H2A.Z and H2A.X (which are present in all organisms) and these variants alter the organisation of the DNA.Due to histones containing a large number of lysine and arginine residues they have a positive net charge which interacts in an electrostatic manner with the negatively charged phosphate groups in DNA. The transcriptional activation or silencing of the chromatin is controlled by ATP-dependent chromatin remodelling factors and histone modifying enzymes which target histone proteins. Both processes function to alter to change the positioning of the nucleosome, allowing the DNA it to be either available to the transcription machinery or inaccessible.
    Peso molecolare:2,086.2 g/mol

    Ref: 3D-CRB1000608

    1mg
    282,00€
    500µg
    206,00€
  • Neurotensin


    Neurotensin (NT) is involved in food absorption in the gut as well as acting as a neurotransmitter in the central nervous system (CNS). In the intestine, NT increases fatty acid translocation, in part by increasing intestinal blood flow. In the CNS, NT regulates pathways associated with ghrelin and leptin which mediate satiety and food ingestion. NT is also involved in the regulation of Luteinizing hormone (LH) and Prolactin release and also plays a role in hypotension- analgesia- gut contraction- vascular permeability- maintaining energy homeostasis- fat storage and metabolic disorders. Higher plasma pro-NT levels are associated with obesity and insulin resistance. NT is therefore a potential target for treating obesity-related diseases.NT is secreted from neuroendocrine cells in the small intestine upon fat intake and exerts its physiological actions by binding three NT receptor (NTR) types- NTR1, NTR2, and NTR3.NTR1 is highly expressed in various tumour cells including- small cell carcinoma/small cell lung cancer (SCLC)- meningiomas- astrocytomas- glioblastoma- pancreatic and colonic carcinoma, and breast and prostate cancers. NTR1 is therefore a possible target for novel cancer therapy.

    Peso molecolare:1,801 g/mol

    Ref: 3D-CRB1000619

    1mg
    206,00€
    5mg
    281,00€
  • HLA-A*02:01 NY-ESO-1 (157-165)


    HLA-A*02 is a class I major histocompatibility complex (MHC) allele which is part of the HLA-A group of human major histocompatibility complex (MHC) leukocyte antigens (HLA). HLA-A is a human MHC class I cell surface receptor and is involved in presenting short polypeptides to the immune system. These polypeptides are typically 7-11 amino acids in length and originate from proteins being expressed by the cell. Cytotoxic T cells in the blood "read" the peptide presented by the complex and should only bind to non-self peptides. If binding occurs, a series of events is initiated culminating in cell death via apoptosis. New York oesophageal squamous cell carcinoma 1 (NY-ESO-1) is part of a well-characterized group of cancer/testis antigens (CTAs). Normally, NY-ESO-1 expression is restricted to germ cells and placental cells, however NY-ESO-1 is also expressed in several cancers including: neuroblastoma- myeloma- metastatic melanoma- synovial sarcoma as well as bladder- oesophageal- hepatocellular- head and neck- non-small cell lung- ovarian- prostate and breast cancers and is often associated with poor prognosis. NY-ESO-1 is also able to elicit a spontaneous immune response, being the most immunogenic among the CTA family members and is therefore the most promising CTA candidate target for cancer immunotherapy.NY-ESO-1 is coexpressed with melanoma antigen gene C1, a member of the MAGE family of CTAs which is involved in cell cycle progression and apoptosis.

    Peso molecolare:1,093.5 g/mol

    Ref: 3D-CRB1001034

    1mg
    282,00€
    500µg
    206,00€
  • Apelin (65-76), human


    Apelin (65-76), human is derived from the apelin peptide which acts as a ligand for the apelin receptor (APJ) G protein coupled receptor and is a substrate for angiotensin converting enzyme 2. Preprapelin, encoded for by APLN located on Xq25-26.1, is cleaved to form either apelin 36 or apelin 17, 12 and 13. As a member of the adipokine hormone family, which are involved in processes such as vascular homeostasis and angiogenesis, the apelin is secreted from adipose tissue.Apelin has been found to be expressed in the spinal cord and the human brain and when performing immunohistochemistry it was observed that apelin-17 is significantly expressed in the human heart, brain, lungs and endothelial cells.Both apelin and the apelin receptor are widely distributed around the body thus apelin has been found to be associated with cardiovascular diseases, obesity, diabetes and cancer. Studies exploring myocardial infarction showed there to be greater apelin mRNA expression during human heart failure compared to in healthy tissue. Apelin protects against heart failure due to, the pyroglutamyl form of apelin, playing a role in decreasing infarct size of myocardial infarctions. Furthermore in rats with hypertension, the expression of apelin and APJ was decreased.
    Peso molecolare:1,402.8 g/mol

    Ref: 3D-CRB1001205

    1mg
    282,00€
    500µg
    206,00€
  • Dystrophin (396-405)


    Forms of inherited muscular dystrophy such as Duchenne muscular dystrophy (DMD) and Becker muscular dystrophy (BMD) result from mutations targeting the dystrophin gene. These disorders are X-linked, progressive, and cause the gradual weakening of the muscles leading to respiratory failure and ultimately reduces the patient lifespan.In DMD, mutations lead to the production of premature stop codons and hence the truncated dystrophin protein product is vulnerable to nonsense mediated decay and degradation. Therefore, dystrophin production in muscle cells is reduced. On the other hand, nonsense mutations which also contribute to DMD, cause exon skipping in BMD and result in an internally truncated protein product which are partially functional. The symptoms of BMD are later onset compared with DMD which develop in patients between 2 to 7 years.Treatments of dystrophin disorders are in clinical trials including antisense oligonucleotide exon skipping and gene therapy. However, the efficacies of these treatments are not easily quantified. Currently levels of muscular dystrophin are quantified by western blot which can be unreliable. The peptide provided here, aligning residues dystrophin (396-405), has been shown to provide absolute quantification of dystrophin levels from biopsies using parallel reaction monitoring. This will hopefully allow better management of dystrophin disorders with better quantifications tools based on dystrophin (396-405). Further study with this dystrophin fragment could prove to be a vital step in the understanding and treatment of dystrophin disorders. Within our catalogue we also have other peptides tested for dystrophin quantification available plus the full-length dystrophin protein.

    Ref: 3D-CRB1001660

    1mg
    282,00€
    500µg
    206,00€
  • dodecapeptide AR71


    The dodecapeptide AR71 prevents melanoma inhibitory activity (MIA) dimerisation and hence inhibits (MIA). It therefore has the potential to be used as a therapeutic in melanoma.

    Peso molecolare:1,550.8 g/mol

    Ref: 3D-CRB1000624

    1mg
    282,00€
    500µg
    206,00€
  • CALP3 - Calcium like peptide 3

    CAS:
    Cell-permeable calmodulin (CaM) agonist that binds to the EF-hand/Ca2+-binding site and can activate phosphodiesterase in the absence of Ca2+ and inhibit Ca2+ mediated cytotoxicity and apoptosis.
    Formula:C44H68N10O9
    Peso molecolare:881.07 g/mol

    Ref: 3D-CRB1000724

    1mg
    282,00€
    500µg
    206,00€
  • CE dipeptide


    CE-acid is a dipeptide of glutamate and cysteine. CE-acid has a formal charge of 0 and a range of biological and chemical uses. EC-acid is also available in our catalogue.

    Peso molecolare:250.1 g/mol

    Ref: 3D-CRB1001693

    1mg
    282,00€
    500µg
    206,00€
  • Galanin (2-30) acid


    Galanin is predominantly an inhibitory neuropeptide expressed in humans and other mammals' brains, spinal cords, and gut. Galanin signalling occurs through three G protein-coupled receptors GalR1-3. Galanin has been implicated in many biologically diverse functions, including nociception, waking and sleep regulation, cognition, feeding, mood regulation and blood pressure regulation. Galanin appears to have neuroprotective activity as its biosynthesis is increased 2-10 fold upon axotomy and during seizure activity in peripheral tissues and the brain.The clinical relevance of galanin is related to several chronic neural disorders, including Alzheimer's disease, epilepsy, depression and cancer- those who suffer from type 2 diabetes mellitus, depression and Alzheimer's disease often express high levels of galanin. Conversely, intervention with galanin agonists (for example, M617, M1145 and M1153) were able to ameliorate disease symptoms such as Alzheimer's and have pro-nociceptive effects. Specifically, activation of GAL2 can alleviate such disease features in human and rodent models. This galanin (2-30) peptide has been used to characterise Galanin's binding sites and affinity for GALR receptors via competition binding analysis. Galanin (2-30) is a full agonist of the GALR2 receptor compared to its affinity for GALR1.
    Peso molecolare:3,098.5 g/mol

    Ref: 3D-CRB1001318

    1mg
    470,00€
    500µg
    386,00€
  • SARS-CoV-2 Nucleoprotein 2 (261-275)


    The coronavirus (CoV) nucleoprotein is the major component of CoV structural proteins. Also known as the nucleocapsid protein, it is an abundant RNA-binding protein critical for viral genome packaging. These factors make nucleoprotein a good target for developing new antiviral drugs. In addition, the identification of epitopes within the nucleoprotein sequence can help design more effective SARS-CoV-2 vaccines.Models have predicted epitopes exhibiting antigenicity, stability and interactions with MHC class-I and class-II molecules. Nucleoprotein (261-275) is an epitope candidate with various HLA restrictions. This epitope can be used to better vaccine design for more durable CD4+ and CD8+ T cell responses for long-lasting immunity.
    Peso molecolare:1,654.9 g/mol

    Ref: 3D-CRB1001759

    1mg
    282,00€
    500µg
    206,00€
  • TAT-AKAP79 (326-336) scrambled amide


    The activation of transient receptor potential cation channel subfamily V member 1 (TRPV1) is believed to play a role in hyperalgesia, asthma and hypertension. TRPV1 is important for neuronal pain detection as well as the detection of heat, capsaicin, protons and the neurotransmitter anandamide.- The scaffold protein AKAP79 targets kinases to phosphorylate TRPV1, however it has been shown that inflammatory intermediates prostaglandin-E2 or bradykinin can activate these kinases creating a route for inflammation to cause hyperalgesia.This product is composed of the TRPV1 interacting residues of AKAP79 reordered into a scrambled sequence and conjugated to the cell penetrating TAT domain at the N-terminus. The scrambled peptide was shown in vivo to have no effect on TRPV1 algesia and thus is a vital control for research work. This product is a vital tool for research into suitable TRPV1 antagonists. The scrambled-TAT peptide is available for purchase in both an acid and amide form, this is the C-terminal amide form.

    Peso molecolare:2,877.6 g/mol

    Ref: 3D-CRB1001280

    1mg
    282,00€
    500µg
    206,00€
  • TAT-CN21


    TatCN21 is an inhibitor peptide for the calcium/calmodulin-dependent protein kinase II (CaMKII), a ubiquitously-expressed multifunctional serine/threonine protein kinase. TatCN21 blocks both autonomous and stimulated CaMKII activity with high selectivity. CaMKII is highly expressed in brain tissue where it regulates several processes including: neurotransmitter synthesis/release, neuronal plasticity- excitability and calcium homeostasis. Glutamate clearance by astrocytes is an essential part of normal excitatory neurotransmission, and accumulation of glutamate in the central nervous system is associated with many neurodegenerative disorders. CaMKII regulates glutamate homeostasis: CaMKII inhibition results in diminished glutamate uptake, dysregulated calcium homeostasis, release of the gliotransmitter ATP and compromise neuronal survival. Loss of CaMKII signalling may be an important factor in excitotoxicity. Peptide was obtained by linking the 11 amino acid human HIV Tat transporter to a 21 amino acid sequence corresponding to the CN21.

    Colore e forma:Powder
    Peso molecolare:3,986.4 g/mol

    Ref: 3D-CRB1001584

    1mg
    470,00€
    500µg
    282,00€
  • TAT - GluR23Y


    TAT-GluR23Y is a cell penetrating peptide that inhibits phosphorylation of AMPA receptor endocytosis.Recent studies have shown that AMPA receptor endocytosis, which is a cellular mechanism underlying the formation of LTD, plays a critical role in facilitating initial extinction of learned fear. Tat-Glur23Y can block regulated AMPA and thereby prevents long-term depression (LTD) in structures such as the nucleus accumbens and dorsal hippocampus.

    Peso molecolare:2,632.4 g/mol

    Ref: 3D-CRB1001142

    1mg
    282,00€
    500µg
    206,00€
  • Azhx-Penetratin


    Identification of cell penetrating conjugates has aided numerous areas of scientific development. The Drosophila transcription factor Antennapedia contains a homeodomain that can be internalised by cells to the cytoplasm and to the nucleus in a receptor-independent mechanism. The key residues for internalisation have been sequenced (RQIKIWFQNRRMKWKK), named penetratin, and used in several studies to aid entry of fusion proteins into cells.The full 60 amino acid homeodomain was fused to a T cell epitope of the influenza nucleoprotein and successfully internalised into T cells for presentation. The fragment known as penetratin was fused to a ligand for Grb-2 resulting in inhibition of downstream Grb-2 signalling events.- Penetratin has also been used in vivo to prime cytotoxic T lymphocytes by conjugating short antigenic peptides to the CPP. This penetratin has been synthesised with an N-terminal 6-azidohexanoic acid (Azhx) which can be used for various applications as a linker.
    Colore e forma:Powder
    Peso molecolare:2,384.4 g/mol

    Ref: 3D-CRB1000909

    1mg
    282,00€
    500µg
    206,00€
  • Anoplin


    Antimicrobial and cytolytic peptide isolated from the venom of the spider wasp Anoplius samariensis. Anoplin has potent and board-spectrum antimicrobial activity against both Gram-positive and Gram-negative bacteria, antifungal properties against some plant pathogenic fungi, and no haemolytic activity against human erythrocytes. At 10 amino acids long, anoplin is the smallest naturally occurring antimicrobial and cytolytic peptide, its small size may have advantages for chemical manipulation and medical application.
    Peso molecolare:1,153.5 g/mol

    Ref: 3D-CRB1000042

    1mg
    254,00€
    500µg
    186,00€
  • dfTAT


    Cell-penetrating peptides  (CPP) conjugated to biomolecular cargo can provide targeted molecular treatments. This could be revolutionary for numerous conditions such as cancer, muscular dystrophy and many more. CPP often use the endosomal system to enter the cell. Still, they vary in their ability to escape the endosome allowing the cargo to reach its intended area within the cell. Most CPP activity escaping the endosome is weak, and the method is unclear.Dimeric fluorescent TAT (dfTAT) is a CPP composed of 2 TAT peptides with an N-terminal fluorophore tetramethylrhodamine. When incubated with cells, it shows a cytosolic localisation. A simple co-incubation method of dfTAT with a cargo results in efficient endosomal leakage and release of the cargo to the cytosol. dfTAT has been shown to efficiently deliver a wide variety of cargos to the cell, including transcription factors, antibodies, and metal-organic framework (MOF) nanoparticles. One of the significant advantages of using dfTAT is that the co-incubation method of delivery allows dfTAT, and the cargo can be added as separate entities. This enables the controlled titration of material into cells through the modulation of cargo concentration independent of dfTAT.

    Peso molecolare:4,074.3 g/mol

    Ref: 3D-CRB1001690

    1mg
    597,00€
    500µg
    470,00€
  • FAM49B (190-198) Mouse


    Fragment of Family with sequence similarity 49 member B (FAM49B), a mitochondria-localized protein that regulates mitochondrial fission and cancer progression. Within tumour environments, such as those seen in pancreatic ductal adenocarcinoma, the expression of FAM49B is reduced. The ability of FAM49B to control redox reactions in the mitochondria allows it to suppress cancer cell proliferation.

    Colore e forma:Powder
    Peso molecolare:1,041.5 g/mol

    Ref: 3D-CRB1001420

    1mg
    282,00€
    500µg
    206,00€
  • SARS-CoV-2 NSP13 (326-340)


    The SARS-CoV-2 non-structural protein 13 (NSP13) has been identified as a target for anti-viral therapeutics due to its highly conserved sequence and is essential for viral replication.  NSP13 is part of the helicase superfamily 1B. As an NTPase and RNA helicase, NSP13 binds to RNA-dependent RNA polymerase and acts in concert with the replication-transcription complex to stimulate backtracking and further activate NSP13 helicase activity. These factors make NSP13 a good target for developing new antiviral drugs. In addition, the identification of epitopes within the NSP13 sequence can help design more effective SARS-CoV-2 vaccines.Models have predicted epitopes exhibiting antigenicity, stability and interactions with MHC class-I and class-II molecules. NSP13 (326-340) is an epitope candidate with various HLA restrictions. This epitope can be used to better vaccine design for more durable CD4+ and CD8+ T cell responses for long-lasting immunity.
    Peso molecolare:1,694 g/mol

    Ref: 3D-CRB1001770

    1mg
    282,00€
    500µg
    206,00€
  • Click Arg9


    Cell penetrating peptides (CPP) are a keen area of molecule design to create the ideal vector for transporting macromolecule cargo into the cell. There is also a crossover of CPP acting as antimicrobial peptides (AMP) due to their ability to permeabilise the lipid membrane. AMPs are now being considered as a tool against the rise of antibiotic-resistant bacteria. CPPs and AMPS tend to be 10 - 30 amino acids long, cationic, and rich in arginine (R) and tryptophan (W). The presence of R and W in the backbone have been used to generate de novo CPP/AMP peptides with improved functions. Of these, nonarginine (R9) was shown to have the highest cellular uptake against other CPPs tested, lowest cytotoxicity and significant antimicrobial activity.R9 is provided here with a N-terminal alkyne attachment. Two of the most regularly encountered functional groups for click chemistry are azides and alkynes, and the azide-alkyne cycloaddition has become the most popular click reaction. The use of click chemistry with alkyne-R9 allows a wide variety of applications and has already been used for conjugation, modification and peptide design.

    Colore e forma:Powder
    Peso molecolare:1,502 g/mol

    Ref: 3D-CRB1000111

    1mg
    282,00€
    500µg
    206,00€
  • Temporin A


    Temporin A is a short, linear, basic and highly hydrophobic anti-microbial peptide (AMP) isolated from the frog, Rana temporaria. Temporin A is particularly active against Gram-positive bacteria including those arranged in biofilms. Temporin A is also active against some Gram-negative bacteria and Leishmania parasites.Temporin A adopts an alpha-helical conformation in a membrane-mimicking environment and is able to perturb the membrane of microbial cells. Temporin A is practically non-haemolytic up to concentrations five-times higher than their minimum inhibitory concentration (MIC) against Gram-positive bacteria.
    Peso molecolare:1,396.76 g/mol

    Ref: 3D-CRB1000023

    1mg
    282,00€
    500µg
    206,00€
  • Histone H3 (1-15) K4Me3, K9Ac, pS10


    Histone 3 (H3) is one of the four core histones (H2A, H2B, H3 and H4) fundamental in compacting eukaryotic DNA into the nucleosome. The nucleosome arises when 147 base pairs of DNA wrap around a H3-H4 tetramer and two H2A-H2B dimers, forming the histone octamer core. Both H4 and H3 are highly conserved and perform roles in binding to segments of DNA which enter and leave the nucleosome and in chromatin formation. Similar to the other core histone, H3 has a globular domain and a flexible N-terminal domain, 'histone tail' which can undergo modifications such as acetylation, methylation, phosphorylation and ubiquitination. The transcriptional activation or silencing of the chromatin is controlled by ATP-dependent chromatin remodelling factors and histone modifying enzymes which target histone proteins. Both processes function to alter the positioning of the nucleosome, allowing the DNA it to be either available or inaccessible to the transcription machinery.The lysine at position 4 of this peptide has been tri-methylated and it is implicated in studies that this modification may remodel the chromatin so that it is more accessible to transcription factors, which may ultimately increase the level of gene expression. The lysine at position 9 has been acetylated, which neutralizes the positive charge on the amino acid, loosening the chromatin structure. This alteration to the accessibility of chromatin promotes the initiation of transcription. Moreover, the serine at position 10 has been phosphorylated, and studies have suggested that this may induce chromatin condensation, and subsequently repress transcription and gene expression.
    Peso molecolare:1,724.9 g/mol

    Ref: 3D-CRB1001702

    1mg
    470,00€
    500µg
    386,00€
  • CCK octapeptide Cholecystokinin (26-33)

    CAS:
    The octapeptide cholecystokinin (26-33), known as CCK-8, has the full biological activity of the full-length cholecystokinin (CCK). CCK acts as a hormone and neurotransmitter and is found in the GI and central nervous systems. CCK-8 is a satiety peptide that inhibits food intake.CCK-8 can also inhibit amanitin uptake into hepatocytes.
    Formula:C49H62N10O13S2
    Peso molecolare:1,063.21 g/mol

    Ref: 3D-CRB1000237

    1mg
    282,00€
    500µg
    206,00€
  • Beclin-1


    The Beclin-1 peptide is derived from a region of the Beclin-1 protein, which interacts with a newly identified negative regulator of autophagy, GAPR-1 (also called GLIPR2) to act as a potent inducer of autophagy. Autophagy is an essential process that maintains cellular homeostasis and carries out lysosome-mediated degradation of unwanted proteins in the cytoplasm. It is often examined when looking at disease pathways because of this regulatory function. While the immune system initiates the removal of viruses and pathogens through the autophagic pathway, some viruses (such as HIV) are able to evade this process.

    Peso molecolare:2,064.22 g/mol

    Ref: 3D-CRB1000187

    1mg
    282,00€
    500µg
    206,00€
  • EBV BNRF1 (1238-1252)


    Cellular immunotherapy is an effective treatment option against Epstein-Barr virus (EBV)-driven lymphoproliferation in recipients of hematopoietic stem cells. However, increasing the number of identified epitope targets will help improve the response rate and success. Viral tegument protein BNRF1 is a critical target in EBV inducing specific CD4+ T-cell responses. 18 epitopes within BNRF1 are known, including  (1238-1252). BNRF1-specific CD4+ T cells are cytotoxic and limit EBV-driven B cell transformation. Work with EBV BNRF1 (1238-1252) epitope and others will help improve T cell immunotherapy and our understanding of host-virus interaction.

    Peso molecolare:1,838.9 g/mol

    Ref: 3D-CRB1001669

    1mg
    282,00€
    500µg
    206,00€
  • (Arg8) Vasotocin


    (Arg8) Vasotocin (AVT) is a member of the neurohypophyseal hormone family which contains 9 amino acids with the cysteines at positions 1 and 6 linked through a disulphide bridge. Within the central nervous system of lower vertebrates, AVT has been shown to play a role as a neuromodulator and controls reproductive behaviour. Furthermore it regulates osmotic and electrolyte balance and blood pressure within the periphery. In the mammalian brain AVT functions through arginine vasopressin (AVP) or oxytocin receptor cross-reactions. Mice have an AVT reactive receptor specific to AVT and neuropeptide S. This AVT which functions to regulate processes such as sleep and reproduction.
    Colore e forma:Powder
    Peso molecolare:1,049.5 g/mol

    Ref: 3D-CRB1000484

    1mg
    386,00€
    500µg
    282,00€
  • L57


    The blood-brain barrier (BBB) is a major obstacle to drug delivery into the central nervous system (CNS), in particular for macromolecules such as peptides and proteins. However, certain macromolecules can reach the CNS via a receptor-mediated transcytosis (RMT) pathway, and low-density lipoprotein receptor-related protein 1 (LRP1) is one of the promising receptors for RMT. L57 can therefore be used for the development of RMT-based drugs for the treatment of CNS diseases.

    Colore e forma:Powder
    Peso molecolare:2,842.3 g/mol

    Ref: 3D-CRB1001192

    1mg
    282,00€
    500µg
    206,00€
  • Neurokinin A (Substance K)


    Neurokinin A (NKA) is a member of the classical tachykinins family of peptides which also includes substance P and neurokinin B. These peptides are primarily found in the nervous system where they act as neurotransmitters and neuromodulators. They also play key roles in neuronal inflammation, and high levels of NKA have been linked to poor prognosis of some tumours.The tachykinin peptides are characterised by a common C-terminal sequence, Phe-X-Gly-Leu-Met-NH2, where X represents either an aromatic (Phe, Tyr) or a branched aliphatic (Val, Ile) amino acid.This C-terminal region is thought to be responsible for activating the receptor. The divergent N-terminal region is thought to play a role in determining the receptor subtype selectivity. NKA binds preferentially to the NK2 receptor.

    Peso molecolare:1,132.6 g/mol

    Ref: 3D-CRB1000222

    1mg
    282,00€
    500µg
    206,00€
  • Motilin (1-10)


    Residues 1-10 of the gastrointestinal hormone motilin, secreted from endocrine cells in the small intestines, mainly from the jejunum and duodenum, in response to the fasting, drinking water or the mechanical stimulus of eating.
    Peso molecolare:1,184.6 g/mol

    Ref: 3D-CRB1000593

    1mg
    282,00€
    500µg
    206,00€
  • Rhodopsin Epitope Tag


    ID4 is a highly versatile epitope tag. The peptide sequence is highly specific to rhodopsin and related photoreceptor proteins, meaning when used with monoclonal antibodies off-target signals are virtually non-existent. ID4 is also devoid of charged residues therefore reducing nonspecific ionic interactions. Monoclonal antibodies also bind to ID4 with high affinity therefore there is less need for inserting multiple copies of ID4.
    Peso molecolare:902.4 g/mol

    Ref: 3D-CRB1001593

    1mg
    282,00€
    500µg
    206,00€
  • Fmoc-β-(7-methoxy-coumarin-4-yl)-Ala-OH

    CAS:
    Fmoc-b-(7-methoxy-coumarin-4-yl)-Ala-OH is a reagent with the CAS No. 524698-40-6, which is used in organic synthesis. It is a versatile building block and useful intermediate that can be used to synthesize other organic compounds. Fmoc-b-(7-methoxy-coumarin-4-yl)-Ala-OH is also used as a reaction component in the synthesis of peptides and proteins, as well as in the preparation of polymers. It has been shown to be an effective building block for complex compounds.
    Formula:C28H23NO7
    Purezza:Min. 95%
    Colore e forma:Powder
    Peso molecolare:485.48 g/mol

    Ref: 3D-FF111350

    25mg
    191,00€
    50mg
    270,00€
    100mg
    407,00€
    250mg
    741,00€
  • Ac-Arg-[Cys-Met-Ava-Arg-Val-Tyr-Ava-Cys]-NH2


    Ac-Arg-[Cys-Met-Ava-Arg-Val-Tyr-Ava-Cys]-NH2 is a peptide that has antagonist activity against melanin, the hormone receptor. This peptide can be used to treat skin pigmentation disorders such as vitiligo, which is an autoimmune disorder in which the melanocytes are destroyed. Ac-Arg-[Cys-Met-Ava-Arg-Val-Tyr-Ava-Cys]-NH2 is also an aminovaleric acid derivative, which can inhibit the production of aminovaleric acid and related compounds.
    Formula:C49H82N16O11S3
    Purezza:Min. 95%
    Peso molecolare:971.22 g/mol

    Ref: 3D-PMC-3881-PI

    1mg
    205,00€
    5mg
    547,00€
  • Fmoc-Ala-Wang Resin (100-200 mesh) 1% DVB


    This is a vivitide catalogue product. Please send your vivitide product enquiry to sales@vivitide.com for an up-to-date price and availability.
    Purezza:Min. 95%

    Ref: 3D-RFA-1306-PI

    1g
    136,00€
    5g
    292,00€
  • Fmoc-Arg(Pbf)-Wang Resin (100-200 mesh) 1% DVB


    Fmoc-Arg(Pbf)-Wang resin is a building block for the synthesis of peptides. It is a resin that is used for the solid phase synthesis of peptides and oligonucleotides with Fmoc chemistry. This resin is provided in powder form, as well as in various particle sizes from 100 to 200 mesh. The resin has been shown to be stable in the presence of DIC/HOBT coupling reactions and can be used with other resins for automated peptide synthesizers.Substitution: 0.3meq/gSwelling: 4.4ml/g (DCM - 30min)
    Purezza:Min. 95%

    Ref: 3D-RFR-1347-PI

    1g
    207,00€
    5g
    588,00€
  • H-His(Trt)-2-ClTrt-Resin (100-200 mesh) 1% DVB


    H-His(Trt)-2-ClTrt-Resin (100-200 mesh) 1% DVB is a resin that is used in the synthesis of peptides. It is a building block for synthesizing peptides and proteins. H-His(Trt)-2-ClTrt-Resin (100-200 mesh) 1% DVB is also used as an alcohol for amine coupling. This resin has been shown to be useful in the synthesis of thiols, amines, and building blocks.
    Purezza:Min. 95%

    Ref: 3D-RHH-11061-PI

    1g
    220,00€
    5g
    733,00€
  • Retatrutide trifluoroacetate

    CAS:
    Retatrutide is a 39 amino acid single peptide with triple agonist activity at the glucagon receptor (GCGR), glucosedependent insulinotropic polypeptide receptor (GIPR), and glucagon-like peptide-1 receptor (GLP-1R). The backbone is conjugated to a C20 fatty diacid moiety at position 17. Retatrutide has a Glucose-dependent insulinotropic polypeptide (GIP) peptide backbone, which then contains three non-coded amino acids. Aib2 (α-amino isobutyric acid) residues at positions 2 and 20 provide stability against Dipeptidyl Peptidase 4 (DPP4) cleavage and contribute to GIP activity. αMeL13 (α-methyl-L-leucine)at position 20 also contributes to GIP and glucagon activity. Retatrutide can be used for the research of obesity obesity, diabetes, and fatty liver disease. It is a works in three ways: stimulating insulin release, suppressing appetite, and promoting fat breakdown.
    Formula:C221H342N46O68xC2HF3O2
    Purezza:Min. 95%
    Colore e forma:Powder
    Peso molecolare:4,731.33 g/mol

    Ref: 3D-FR04567

    5mg
    282,00€
    10mg
    378,00€
    25mg
    538,00€
    50mg
    892,00€
    100mg
    1.442,00€
  • H-Ser-Leu-Ile-Gly-Arg-NH2


    Hypertension is a condition that affects the heart and blood vessels. It is caused by a number of factors, including increased blood pressure, high levels of cholesterol, diabetes, and genetics. Hypertension can lead to stroke, kidney disease, heart failure, or death. This drug was designed to target hypertension by activating protease-activated receptor (PAR) peptides in the body. PAR peptides are found in many tissues throughout the body and are involved in inflammation and coagulation. PAR2 has been shown to be involved in cardiovascular diseases such as atherosclerosis and coronary artery disease. The drug was designed for use as an oral treatment for hypertension and related conditions.
    Formula:C23H45N9O6
    Purezza:Min. 95%
    Peso molecolare:543.67 g/mol

    Ref: 3D-PAR-3743-PI

    1mg
    136,00€
    5mg
    370,00€
  • Fmoc-Asn(Trt)-Rink-Amide MBHA Resin


    Fmoc-Asn(Trt)-Rink-Amide MBHA Resin is an ion channel blocker and a research tool that can be used to study the effects of peptides and other small molecules on ion channels. It is a high purity resin with a CAS number of 47794-33-4. The Fmoc-Asn(Trt)-Rink-Amide MBHA Resin is an inhibitor of the Ca2+ channel and the K+ channel and it can be used in pharmacology, cell biology, and immunology research.
    Purezza:Min. 95%

    Ref: 3D-RFN-10013-PI

    1g
    197,00€
    5g
    653,00€
  • H-Asp-[Pen-Phe-Trp-Lys-Tyr-Cys]-Val-OH


    H-Asp-[Pen-Phe-Trp-Lys-Tyr-Cys]-Val-OH is a peptide that belongs to the class of biochemicals. It is a disulfide-rich peptide that is found in the brain, and has been shown to increase blood flow and activate the hypothalamic pituitary adrenal axis in animals. Urotensin II and related peptides are also found in the brain, but have not been shown to have any effect on blood flow or hormone levels.
    Formula:C52H68N10O12S2
    Purezza:Min. 95%
    Peso molecolare:1,089.31 g/mol

    Ref: 3D-PUT-3640-PI

    1mg
    275,00€
  • Fmoc-Thr(tBu)-Rink-Amide MBHA Resin


    Fmoc-Thr(tBu)-Rink-Amide MBHA Resin is a resin that can be used for the synthesis of peptides. It is an inhibitor of Protein interactions, Activator, Ligand, and Receptor. This resin can be used in research to study ion channels and antibodies. Fmoc-Thr(tBu)-Rink-Amide MBHA Resin is also a high purity product with CAS No.
    Purezza:Min. 95%

    Ref: 3D-RFT-10031-PI

    1g
    197,00€
    5g
    653,00€
  • KGF 2 Human


    KGF 2 is a recombinant human protein that binds to the KGFR-2 receptor, which regulates cell growth and differentiation. It is a potent inhibitor of cell proliferation and has been shown to inhibit the growth of breast cancer cells in vitro. The KGF 2 peptide is synthesized as a fusion protein with six histidine residues on the N-terminus and two cysteine residues on the C-terminus. This product can be used as a research tool, as well as an antibody for immunodetection of KGFR-2 protein in tissue culture.
    Purezza:Min. 95%

    Ref: 3D-CYT-303

    1mg
    4.969,00€
    5µg
    148,00€
    25µg
    329,00€
  • Tylotoin


    Tylotoin is a peptide that has been shown to have a proliferative effect on endothelial cells. It also acts as an inhibitor of cell proliferation in keratinocytes and fibroblasts, without affecting the proliferation of other cell types. Tylotoin is structurally similar to the disulfide-rich peptides from the salamander Tylototriton verrucosus, which are known for their wound healing properties. The proliferative effects of tylotoin are thought to be due to its ability to inhibit the proteolytic enzymes that degrade extracellular matrix proteins in endothelial cells.
    Formula:C59H108N24O16S2
    Purezza:Min. 95%
    Peso molecolare:1,473.8 g/mol

    Ref: 3D-TYL-3814-PI

    1mg
    404,00€
    5mg
    1.282,00€
  • Proinsullin, human


    Proinsulin is a peptide hormone that is made up of the amino acid chain, insulin. It is synthesized in the beta cells of the pancreas and is stored in granules with other hormones. The proinsulin molecule consists of two chains linked by disulfide bonds, which are broken down to release insulin when needed. Proinsulin can activate receptors on cells, which leads to a number of physiological responses including changes in metabolism and ion channels. It has been shown to be an important research tool for studying protein interactions and pharmacology. Proinsulin also has potential as a therapeutic agent for the treatment of diabetes mellitus type I due to its ability to inhibit glucose production in the liver.
    Purezza:Min. 95%

    Ref: 3D-AA-27

    50µg
    850,00€
    100µg
    1.532,00€
    250µg
    3.481,00€
  • H-Asp(2-ClTrt-Resin)-OtBu (α Ester)


    H-Asp(2-ClTrt-Resin)-OtBu (α Ester) is a building block that is used in peptide synthesis. It can be resubstituted with the amino acid, aspartic acid, and used in the formation of peptides. This resin is insoluble in water and soluble in dichloromethane and dimethylformamide. The H-Asp(2-ClTrt-Resin)-OtBu (α Ester) can also be used to form disulfides or thioethers.
    Purezza:Min. 95%

    Ref: 3D-RHD-11075-PI

    1g
    263,00€
    5g
    827,00€
  • Tirzepatide

    CAS:

    Cymit Quimica provides this product solely for uses within the scope of any statute or law providing for an immunity, exemption, or exception to patent infringement (“Exempted Uses”), including but not limited to 35 U.S.C. § 271(e)(1) in the United States, the Bolar type exemption in Europe, and any corresponding exception to patent infringement in any other country. It is the sole responsibility of the purchaser or user of this product, and the purchaser or user of this product agrees to engage only in such Exempted Uses, and to comply with all applicable intellectual property laws and/or regulations. The purchaser of this product agrees to indemnify Cymit Quimica against all claims in connection with the performance of the respective commercial agreement (e.g. supply agreement) and possible infringements of intellectual property rights.

    Formula:C225H348N48O68
    Purezza:Min. 95%
    Colore e forma:Powder
    Peso molecolare:4,813 g/mol

    Ref: 3D-FT181880

    5mg
    282,00€
    10mg
    444,00€
    25mg
    662,00€
    50mg
    841,00€
    100mg
    1.190,00€
  • Ovalbumin (257-264) (chicken) acetate salt

    CAS:
    Ovalbumin (257-264) is an acetate salt of a fragment of the protein ovalbumin.
    Formula:C45H74N10O13
    Purezza:Min. 95%
    Colore e forma:Solid
    Peso molecolare:963.13 g/mol

    Ref: 3D-FO110243

    2mg
    194,00€
    5mg
    322,00€
    10mg
    454,00€
    25mg
    765,00€
    50mg
    1.202,00€
  • H-Pro-Val-OH

    CAS:

    H-Pro-Val-OH is an amide that is used to treat renal disorders by inhibiting leukocyte elastase. It has been shown to be a potent inhibitor of serine proteases, including chymotrypsin and trypsin. H-Pro-Val-OH binds to the active site on serine proteases and blocks the release of peptides from the enzyme. The binding constant for H-Pro-Val-OH with chymotrypsin was found to be in the range of 3 x 10 M, which is significantly higher than that for other amides. In addition, H-Pro-Val-OH inhibits cytolysis by lysosomal enzymes and protects against liver injury caused by chronic liver disease. This drug also shows low molecular weight and high water solubility, making it effective in treating acute hepatitis.

    Formula:C10H18N2O3
    Purezza:Min. 95%
    Colore e forma:Powder
    Peso molecolare:214.26 g/mol

    Ref: 3D-FP108165

    1g
    1.003,00€
    100mg
    269,00€
    250mg
    451,00€
    500mg
    723,00€
  • rec IL-4 (murine)

    CAS:
    Please enquire for more information about rec IL-4 (murine) including the price, delivery time and more detailed product information at the technical inquiry form on this page
    Purezza:Min. 95%

    Ref: 3D-FR108526

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  • H1 labeled 4-peptide mixture


    H-VNSVIEK^-OHH-EQLSSVSSFER^-OHH-TLDYHDSNVK^-OHH-ITFEATGNLVAPR^-OHR^ = Arginine (U-13C6,15N4)K^ = Lysine (U-13C6,15N2)Peptide purity: >98%AAA: Concentration - Duplicate100 aliquots/pack total to equal 1nmol/peptide/vial dry aliquots

    Ref: 3D-PH00611

    1piece
    880,00€
  • H-Phe-Pro-OH

    CAS:

    H-Phe-Pro-OH is a cyclic peptide that is a structural mimic of the natural amino acid gamma-aminobutyric acid (GABA) and has been shown to be an effective inhibitor of the p450 enzymes responsible for carcinogen activation. The peptide binds to response elements in DNA and RNA, which prevents transcription of genes that are involved in cancer development. H-Phe-Pro-OH also inhibits collagen production and has hemolytic activity due to hydrogen bonding with erythrocytes. This peptide can be used as an antimicrobial agent against Gram negative bacteria, including Pseudomonas aeruginosa, Klebsiella pneumoniae, Escherichia coli, and Salmonella typhimurium. In addition, it has been shown to inhibit the growth of Gram positive bacteria such as Staphylococcus aureus and Clostridium perfringens. The mechanism by which this compound inhibits bacterial growth is

    Formula:C14H18N2O3
    Purezza:Min. 95%
    Colore e forma:Powder
    Peso molecolare:262.3 g/mol

    Ref: 3D-FP108146

    1g
    490,00€
    250mg
    243,00€
    500mg
    363,00€
  • H-Ile-Asn-OH

    CAS:
    H-Ile-Asn-OH is a chloroplastic amide that is used as a substrate in polymerase chain reactions. It can be used to study the structure of proteins and enzymes by the use of monoclonal antibodies. H-Ile-Asn-OH has been sequenced and assayed, and found to have high binding affinity for carboxylate groups. This chemical has been shown to have multidomain structures as well as an isotype that is specific for triticum aestivum. H-Ile-Asn-OH may also be involved in plant physiology due to its role in photosynthesis.
    Formula:C10H19N3O4
    Peso molecolare:245.28 g/mol

    Ref: 3D-FI108074

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  • H-D-Tyr-Val-NH2

    CAS:

    H-D-Tyr-Val-NH2 is a regulatory group that acts as the prosthetic group for a number of peptidyl and peptide hormones. H-D-Tyr-Val-NH2 is also involved in catalytic mechanism, as it is the amino acid responsible for the formation of peptide bonds in proteins. H-D-Tyr-Val-NH2 is found in high concentrations in the cerebriform tissue and has been shown to be important for the biosynthesis of amides, which are prohormones. H-D-Tyr-Val NH2 also participates in a number of cellular reactions, including those that have a kinetic rate.

    Formula:C14H21N3O3
    Peso molecolare:279.33 g/mol

    Ref: 3D-FT108222

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  • Influenza B labeled 5-peptide mixture


    Influenza B labelled 5-peptide mixture of: H-SHFANLK^-OHH-SYFANLK^-OHH-GVLLPQK^-OHH-NLNSLSELEVK^-OHH-GILLPQK^-OH K^ = Lysine (U-13C6,15N2) 100 aliquots/pack total to equal 1nmol/peptide/vial dry aliquots

    Ref: 3D-PI17024

    1piece
    1.001,00€
  • Ac-CRAELEKHGYKMETS


    Ac-CRAELEKHGYKMETS is a custom research peptide; min purity 95%, TFA salt. For different specs please use the Peptide Quote Tool

    Ref: 3D-PA00005

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  • H-SSIMR^-OH


    Peptide H-SSIMR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

    Ref: 3D-PP41781

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  • Hrk BH3 amide


    A peptide derived from the Hrk (Harakiri) protein, which is a pro-apoptotic member of the BH3-only family within the larger Bcl-2 family of proteins. The BH3 domain of Hrk, contained in the Hrk BH3 peptide, is the critical region responsible for promoting apoptosis by interacting with and neutralizing anti-apoptotic proteins like Bcl-2, Bcl-xL, and Mcl-1.The BH3 domain within the Hrk BH3 peptide binds to anti-apoptotic proteins, disrupting their ability to prevent apoptosis. This releases pro-apoptotic proteins like Bax and Bak, allowing them to oligomerize and permeabilize the mitochondrial outer membrane. This leads to the release of cytochrome c and the activation of downstream caspases, which execute cell death.Hrk specifically targets Bcl-xL and Mcl-1 more efficiently than some other BH3-only proteins, making it a potent inducer of apoptosis in cells where these anti-apoptotic proteins are overexpressed, such as in certain cancer cells.

    Ref: 3D-PP50424

    10mg
    471,00€
  • Boc-D-Leu-OH • H2O

    CAS:

    Boc-D-Leu-OH • H2O is an intramolecular hydrogen. It has a helical structure and forms hydrogen bonds with other molecules. Boc-D-Leu-OH • H2O is a cyclic peptide with a hydrophobic side chain and a hydrophilic head group. The peptide has been shown to have antimicrobial activity in the biliary and intestinal tract, as well as chronic pain relief properties. Boc-D-Leu-OH • H2O was found to be effective in animal studies for neuropathic pain, which may be due to its amide structure. A silico analysis revealed that the drug substance had a high binding affinity for the mu opioid receptor and could potentially be used to treat chronic pain caused by inflammation.

    Formula:C11H21NO4•H2O
    Purezza:Min. 95%
    Peso molecolare:249.31 g/mol

    Ref: 3D-BDL-2603

    1g
    169,00€
    5g
    195,00€
    25g
    586,00€
  • H-ALP^AP^IEK^-OH


    Peptide H-ALP^AP^IEK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

    Ref: 3D-PP47420

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  • Z-Leu-Leu-Glu-MCA

    CAS:
    L-Leu-Leu-Glu-MCA is a research tool that activates the receptor. It is a ligand that binds to the receptor, activating it. L-Leu-Leu-Glu-MCA is a small molecule that has been shown to be an antagonist of ion channels in cell biology. It has been shown to inhibit protein interactions and peptide synthesis by inhibiting the binding of ATP. L-Leu-Leu-Glu-MCA also acts as an inhibitor of ion channels and high purity protein interactions, which may be due to its competitive inhibition of ATP binding. Ligands are used in pharmacology for studying protein interactions or inhibiting enzyme activity. The CAS No. for this compound is 348086-66-8.
    Formula:C35H44N4O9
    Purezza:Min. 95%
    Peso molecolare:664.75 g/mol

    Ref: 3D-MLG-3179-V

    5mg
    335,00€
  • Boc-Asn-OH

    CAS:
    Boc-Asn-OH is a glycopeptide that has a basic structure. It is soluble in water and hydrochloric acid. Boc-Asn-OH has been shown to have antibacterial activity against methicillin-resistant Staphylococcus aureus (MRSA) and Clostridium perfringens, as well as good solubility in organic solvents such as chloroform and acetonitrile. Preparative high performance liquid chromatography (HPLC) of Boc-Asn-OH reveals an amide, toxicity studies, proton, oligosaccharides, disulfide bond, thp-1 cells, conformational properties, esters hydrochloride.
    Formula:C10H19NO4
    Purezza:Min. 95%
    Peso molecolare:232.23 g/mol

    Ref: 3D-BLN-2060

    5g
    198,00€
    25g
    222,00€
    100g
    465,00€
  • Melanocyte Protein PMEL 17 (44-59) (human, bovine, mouse)

    CAS:
    Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool
    Formula:C95H137N27O28
    Peso molecolare:2,105.3 g/mol

    Ref: 3D-PP50366

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  • H-FGQGSGPIVLDDVR^-OH


    Peptide H-FGQGSGPIVLDDVR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

    Ref: 3D-PP40167

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  • H-SFGNPFEPQAR^-OH


    Peptide H-SFGNPFEPQAR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

    Ref: 3D-PP41773

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  • Ac-RNEIQSLV-NH2


    Peptide Ac-RNEIQSLV-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

    Ref: 3D-PP47469

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  • H-DMQLGR^-OH


    Peptide H-DMQLGR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

    Ref: 3D-PP40523

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  • H-DPLNVLKPR^-OH


    Peptide H-DPLNVLKPR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

    Ref: 3D-PP42421

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  • [D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P

    CAS:
    Substance P is a neuropeptide that belongs to the Feeding Regulatory Peptides family. It is synthesized in the hypothalamus and secreted by neurons in the spinal cord, brainstem, and gut. Substance P has been shown to regulate feeding behavior through its interaction with opioid receptors and the release of other neurotransmitters. The synthetic form of this peptide has been shown to reduce body fat in animal models and increased sensitivity to insulin in diabetic patients. This peptide also reduces camp levels in rats, which may be due to its ability to stimulate secretion of camp from pancreatic cells.
    Formula:C79H109N19O12
    Purezza:Min. 95%
    Peso molecolare:1,516.87 g/mol

    Ref: 3D-PGH-3652-PI

    1mg
    141,00€
  • Camostat Mesilate

    CAS:

    Camostat mesilate is a prodrug that is metabolized to the active form, pemastatin. It is used for the treatment of bowel disease and squamous cell carcinoma. Camostat mesilate inhibits the TNF-α receptor by binding to its response element in vitro and in vivo. The biological properties of camostat mesilate are due to its ability to inhibit TNF-α production by binding to the TNF-α receptor, thereby preventing activation of transcription factors such as nuclear factor kappa B (NFκB). In vitro assays have shown that camostat mesilate induces apoptosis in human carcinoma cell lines through inhibition of growth factor-β1. This drug has also been shown to be effective in treating viral infections, including HIV and herpes zoster.

    Formula:C20H22N4O5•CH3SO3H
    Purezza:Min. 95%
    Peso molecolare:494.5 g/mol

    Ref: 3D-ISP-3606-PI

    10mg
    135,00€
    50mg
    328,00€
    500mg
    1.462,00€
  • pHLIP WT


    Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool
    Peso molecolare:4,525.87 g/mol

    Ref: 3D-PP50437

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  • H-Val-Lys-Gly-Ile-Leu-Ser-NH2

    CAS:
    H-Val-Lys-Gly-Ile-Leu-Ser-NH2 is a biologically active peptide. It is a peptide that is derived from the amino acid sequence of protease activated receptor 2 (PAR2) and has been shown to induce coagulation. This peptide has also been shown to have cardiovascular effects, such as reducing blood pressure, and may be useful in the treatment of hypertension.
    Formula:C28H54N8O7
    Purezza:Min. 95%
    Peso molecolare:614.79 g/mol

    Ref: 3D-PAR-3896-PI

    1mg
    136,00€
    5mg
    306,00€
  • H-PVSKMRMATPLLMQA-OH


    Peptide H-PVSKMRMATPLLMQA-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

    Formula:C72H12N20O19S3
    Peso molecolare:1,674.1 g/mol

    Ref: 3D-PP45916

    1mg
    322,00€
    10mg
    362,00€
    100mg
    657,00€
  • H-PRPRPRPRPRPRPRPRPRPRPRPRPRPRPRPRPRPRPRPRPRPRPRPRPR-OH


    H-PRPRPRPRPRPRPRPRPRPRPRPRPRPRPRPRPRPRPRPRPRPRPRPRPR-OH is a custom research peptide; min purity 95%, TFA salt. For different specs please use the Peptide Quote Tool
    Formula:C275H477N125O51
    Peso molecolare:6,350.54 g/mol

    Ref: 3D-PH00388

    1mg
    741,00€
    10mg
    918,00€
    100mg
    1.925,00€
  • Leu-Val-Val


    Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool
    Formula:C16H31N3O4
    Peso molecolare:329.44 g/mol

    Ref: 3D-PP50653

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  • Ac-Leu-Leu-Met-H (Aldehyde)

    CAS:

    Ac-Leu-Leu-Met-H (Aldehyde) is a tetrazolium dye that is used as a biological stain for the detection of bacteria in infectious diseases. It binds to toll-like receptor 4 on macrophages and other cells, which triggers a cascade of events leading to bacterial cell lysis. Aldehyde also has been shown to be an autophagy inducer and can cause neuronal death when administered in high doses.

    Formula:C19H35N3O4S
    Purezza:Min. 95%
    Peso molecolare:401.57 g/mol

    Ref: 3D-IAL-3678-PI

    5mg
    136,00€
  • H-LDSIICVK^-OH


    Peptide H-LDSIICVK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

    Ref: 3D-PH00306

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  • H-QQF^FGLM-NH2


    Peptide H-QQF^FGLM-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

    Ref: 3D-PP41741

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  • CGRP (Rat)

    CAS:

    CGRP (Rat) product with the disulfide Bonds: Cys2-Cys7 and available as a 0.1 mg vial. CGRP is the calcitonin gene-related peptide (CGRP), a neuropeptide that plays an important role in the regulation of vascular tone and blood flow, as well as pain perception, inflammation, and neurogenic inflammation. It is a potent vasodilator and has been implicated in a wide range of physiological and pathophysiological processes.
    This product has the potential for use in the study of the physiological and pathological roles of CGRP and to investigate the effects of CGRP on blood vessels, neurons, and other tissues. It has also been used to develop models of migraine headaches and other conditions associated with CGRP dysfunction.

    Formula:C162H262N50O52S2
    Purezza:Min. 95%
    Peso molecolare:3,806.2 g/mol

    Ref: 3D-PCG-4163-S

    100µg
    498,00€
  • 5-FAM-LRRASLG-OH


    Peptide 5-FAM-LRRASLG-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

    Ref: 3D-PP45685

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  • H-ESLITLIEK^-OH


    Peptide H-ESLITLIEK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

    Ref: 3D-PP47254

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  • HRKy peptide


    HRK-Y is a synthetic BH3 peptide that selectively antagonizes BCL-XL, a pro-survival protein of the Bcl-2 family. This interaction disrupts the balance of Bcl-2 family proteins, leading to cytochrome c release and subsequent apoptosis in susceptible cancer cells. HRK-Y is utilized in BH3 profiling assays to assess the sensitivity of cancer cells to BH3-mimetic drugs and to identify potential synergistic effects with NK cell-based therapies.

    Ref: 3D-PH17013

    1mg
    378,00€
    10mg
    726,00€
    25mg
    1.202,00€
  • [Arg8]-Vasopressin

    CAS:
    Vasopressin is a peptide antidiuretic hormone, originating from the hypothalamus, that regulates water balance in the body. It is also known as arginine vasopressin or antidiuretic hormone (ADH). The clinical efficacy of vasopressin has been evaluated using in vitro methods on mouse monoclonal antibody production cells, blood sampling, and microdialysis probes for monitoring blood pressure. This product is available in the salt form: Acetate.
    Formula:C46H65N15O12S2
    Purezza:Min. 95%
    Peso molecolare:1,084.25 g/mol

    Ref: 3D-VAS-3878-PI

    1mg
    289,00€
    5mg
    527,00€
  • MOCAc-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2

    CAS:
    MOCAc-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 is a peptide that has been shown to inhibit the activity of ADAM17. It blocks the cleavage of proMMP1, MMP2, and MMP9 and inhibits collagenase, stromelysin, and cathepsin activities. This peptide may be useful for the prevention and treatment of diseases associated with excessive proteolytic activity such as arthritis or cancer.
    Formula:C55H80N16O16
    Purezza:Min. 95%
    Peso molecolare:1,221.35 g/mol

    Ref: 3D-SMO-3670-PI

    1mg
    355,00€
    5mg
    646,00€
  • H-YTDV^SNMSHLA-OH


    Peptide H-YTDV^SNMSHLA-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

    Ref: 3D-PH00604

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  • LCBiot-GSGSSRGGSGSGGSGGGGSKL-NH2


    Peptide LCBiot-GSGSSRGGSGSGGSGGGGSKL-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

    Ref: 3D-PP46632

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  • (3,5-Difluorophenylacetyl)-Ala-Phg-OtBu

    CAS:

    (3,5-Difluorophenylacetyl)-Ala-Phg-OtBu is a secretase inhibitor that inhibits the enzyme that cleaves amyloid precursor protein (APP) to release beta-amyloid. It has been shown to prevent the formation of plaques in the brain and may be used to treat Alzheimer's disease. (3,5-Difluorophenylacetyl)-Ala-Phg-OtBu has also been shown to inhibit the production of tumor necrosis factor alpha (TNFα), which is involved in inflammation and carcinogenesis. The drug has been shown to reduce myocardial infarct size by preventing cardiac cell death and reducing inflammation following a heart attack. It is also active against multiple types of cancer cells, including carcinoma cell lines and multidrug resistant cells.

    Formula:C23H26N2O4F2
    Purezza:Min. 95%
    Peso molecolare:432.47 g/mol

    Ref: 3D-IGS-3641-PI

    10mg
    331,00€
  • H-IDEALER^-OH


    Peptide H-IDEALER^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

    Ref: 3D-PH00246

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  • H-HGEVCPAGW-NH2


    Peptide H-HGEVCPAGW-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

    Ref: 3D-PP47546

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  • H-AKPEAPGEDASPEEL^SRYYASL^RHYL^NLVTRQRY-OH


    H-AKPEAPGEDASPEELSRYYASLRHYLNLVTRQRY-OH is a custom research peptide; min purity 95%, TFA salt. For different specs please use the Peptide Quote Tool
    Formula:C190H288N54O57
    Peso molecolare:4,240.7 g/mol

    Ref: 3D-PH00027

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  • Aoa-KRRGSTCVLA-NH2


    Peptide Aoa-KRRGSTCVLA-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

    Ref: 3D-PA00020

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  • H-DLSLEEIQK^-OH


    Peptide H-DLSLEEIQK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

    Ref: 3D-PH00091

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  • H-SIAFSR^-OH


    Peptide H-SIAFSR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

    Ref: 3D-PH00463

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  • H-K^IADYNYKL-OH


    Peptide H-K^IADYNYKL-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

    Ref: 3D-PP49309

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  • H-EGYLQIGANTQAAQK^-OH


    Peptide H-EGYLQIGANTQAAQK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

    Ref: 3D-PH00113

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  • H-SAINNYAQKL-OH


    Peptide H-SAINNYAQKL-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

    Ref: 3D-PP45415

    1mg
    242,00€
    10mg
    378,00€
    100mg
    673,00€
  • Ac-Leu-Leu-Nle-H (Aldehyde)

    CAS:
    Ac-Leu-Leu-Nle-H (Aldehyde) is a Toll-like receptor ligand that is active against bowel disease. Aldehyde has been shown to have chemotherapeutic effects in vitro and in vivo, even at low doses. It also inhibits the growth of certain cancer cells by inducing apoptosis, which may be due to its ability to activate the nuclear factor kappa B/Toll-like receptor pathway. This agent has been shown to bind to DNA, inhibit transcription, and induce programmed cell death. Aldehyde also binds to proteins that are involved in protein synthesis and cell division. These properties make it useful for the treatment of infectious diseases and cancer.
    Formula:C20H37N3O4
    Purezza:Min. 95%
    Peso molecolare:383.54 g/mol

    Ref: 3D-IAL-3671-PI

    5mg
    136,00€
  • Boc-Lys(Z)-OH

    CAS:

    Boc-Lys(Z)-OH is an amino acid that is used as a building block for peptide synthesis. It can be used to synthesize Boc-protected L-amino acids, which are useful in the chemical synthesis of peptides and proteins.

    Formula:C19H28N2O6
    Purezza:Min. 95%
    Peso molecolare:380.44 g/mol

    Ref: 3D-BLK-2108

    5g
    222,00€
    25g
    343,00€
    100g
    944,00€
  • LCBiot-GGG-OH


    Peptide LCBiot-GGG-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

    Ref: 3D-PP43714

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  • H-VGDTLNLNLR^-OH


    Peptide H-VGDTLNLNLR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

    Ref: 3D-PP41759

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  • Ac-Nle-Cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2

    CAS:

    Ac-Nle-Cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2, also known as cycloastragenol, is a synthetic cyclic peptide that inhibits the activity of adipose β3 adrenergic receptors, leading to reduced fat accumulation. Cycloastragenol has been shown to inhibit the formation of atherosclerotic lesions in mice and may have antiatherogenic effects. It also has been shown to inhibit tumor growth in some skin cancer models and has immunosuppressive effects.

    Formula:C50H69N15O9
    Purezza:Min. 95%
    Peso molecolare:1,024.2 g/mol

    Ref: 3D-PMC-3683-PI

    1mg
    175,00€
    5mg
    500,00€
  • Fmoc-Phe-OH

    CAS:

    Fmoc-Phe-OH is a natural compound that has been shown to have antimicrobial properties. The biological properties of Fmoc-Phe-OH are not well understood, but it has been shown to have anticancer effects in some cases and to inhibit axonal growth when combined with the protein laminin. Fmoc-Phe-OH can be synthesized by the reaction of pheine with trifluoroacetic acid followed by treatment with h9c2 cells. The analytical method for determining the concentration of Fmoc-Phe-OH is based on intramolecular hydrogen exchange between hydrogen atoms on the amide group and hydrogens on neighboring methylene groups. This process releases heat, which is detected by a thermometer.
    END>

    Formula:C24H21NO4
    Purezza:Min. 98.0 Area-%
    Peso molecolare:387.44 g/mol

    Ref: 3D-FLF-1730-PI

    5g
    136,00€
    25g
    218,00€
    100g
    564,00€
  • HXB2 gag NO-20/aa77 - 91


    Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool

    Peso molecolare:1,768 g/mol

    Ref: 3D-PP49960

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  • H-LPTDSELAPR^-OH


    Peptide H-LPTDSELAPR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

    Ref: 3D-PP40555

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  • Iberiotoxin

    CAS:

    Iberiotoxin a synthetic scorpion toxin sourced from the Buthus tamulus scorpion, has disufide bonds formed between Cys7-Cys28, Cys13-Cys33, and Cys17-Cys35. This prodict can be used as a Ca2+-Activated K+ Channel Blocker (Maxi-K+ Channel Blocker). This peptide can be used in pharmacological studies to investigate the effects of Iberiotoxin on various ion channels and receptors.

    Formula:C179H274N50O55S7
    Purezza:Min. 95%
    Peso molecolare:4,230.8 g/mol

    Ref: 3D-PIB-3813-PI

    1mg
    605,00€
    5mg
    2.340,00€
    500µg
    341,00€
  • H-HLWYLLDLK^-OH


    Peptide H-HLWYLLDLK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

    Ref: 3D-PP42481

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  • FitC-(bA)-Bim BH3 (52-71) amide


    Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool

    Ref: 3D-PP50470

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  • H-EALDESIPPVSFWR^-OH


    Peptide H-EALDESIPPVSFWR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

    Ref: 3D-PP41185

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  • H-FLRGRAYGL^-OH


    Peptide H-FLRGRAYGL^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

    Ref: 3D-PH00154

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  • Boc-D-Ile-OH • 1/2 H2O

    CAS:

    Boc-D-Ile-OH is a cyclohexanone that can be used in peptide synthesis. It has been shown to have affinity for the Tools for Peptide Synthesis and is able to activate primary tumors with metastasis. Boc-D-Ile-OH has been shown to have kinetic parameters, and its pharmacophores are characterized by an organic chemistry approach. This compound is a serine protease inhibitor that blocks the activity of other serine proteases such as chymotrypsin and trypsin.

    Formula:C13H21NO4H2O
    Purezza:Min. 95%
    Peso molecolare:240.3 g/mol

    Ref: 3D-BDI-2629

    1g
    1.276,00€
    5g
    2.713,00€
  • H-DIVGAVLK^-OH


    Peptide H-DIVGAVLK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

    Ref: 3D-PH00085

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  • H-VYI^HP-OH


    Peptide H-VYI^HP-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

    Ref: 3D-PP41825

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  • H-ASGPGGGAPR^-OH


    Peptide H-ASGPGGGAPR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

    Ref: 3D-PP47690

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  • Aminomethylated Polystyrene Resin • HCl (200-400 mesh) 1% DVB


    Aminomethylated Polystyrene Resin • HCl (200-400 mesh) 1% DVB is a purified solid resin that has been chemically modified with amine groups. This product can be used as an inhibitor, activator, or ligand in research applications. Aminomethylated Polystyrene Resin • HCl (200-400 mesh) 1% DVB is also useful as a reagent for Protein interactions and Receptor binding studies. It is available in high purity and can be used as a research tool in Cell Biology and Pharmacology experiments.
    Purezza:Min. 95%

    Ref: 3D-RAM-1049-PI

    5g
    141,00€
    25g
    454,00€
  • Ac-VQIVYK-OH


    Peptide Ac-VQIVYK-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

    Ref: 3D-PP49426

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  • α-fetoprotein (158-166)


    Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool
    Formula:C59H85N11O14S1
    Peso molecolare:1,204.44 g/mol

    Ref: 3D-PP50726

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  • SIVmac239 - 14


    Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool

    Peso molecolare:1,613 g/mol

    Ref: 3D-PP50010

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  • Cyclo(Arg-Ala-Asp-D-Phe-Cys)

    CAS:
    Cyclo(Arg-Ala-Asp-D-Phe-Cys) is a peptide macrocycle with the amino acid sequence Arg-Ala-Asp-D-Phe-Cys. RGD peptides are biologically active peptides that have been shown to be useful in the treatment of various conditions, including angiogenesis and cancer. Cyclo(Arg-Ala-Asp-D-Phe-Cys) is a cyclic peptide composed of nine amino acids, where each amino acid has one chiral center. This results in two possible stereoisomers (mirror images) for the molecule. The biological activity of this compound has yet to be fully determined.
    Formula:C25H36N8O7S
    Purezza:Min. 95%
    Peso molecolare:592.67 g/mol

    Ref: 3D-PCI-3960-PI

    1mg
    155,00€
    5mg
    362,00€
    25mg
    1.137,00€
  • H-NNLEAL^EDFEK-OH


    Peptide H-NNLEAL^EDFEK-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

    Ref: 3D-PP40727

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  • H-AWW-NH2


    Peptide H-AWW-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

    Ref: 3D-PP48297

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    Prezzo su richiesta
  • H-LQVTDSGLYRCVIYHPP-NH2


    Peptide H-LQVTDSGLYRCVIYHPP-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

    Ref: 3D-PP44044

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  • Ac-CSDTDSTELASIL-OH


    Peptide Ac-CSDTDSTELASIL-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

    Ref: 3D-PP44361

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  • H-LANDAAQVK^-OH


    Peptide H-LANDAAQVK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

    Ref: 3D-PP47408

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  • H-NGFFF-NH2


    Peptide H-NGFFF-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

    Ref: 3D-PP43144

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  • H-ASTIEMPQQAR^-OH


    Peptide H-ASTIEMPQQAR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

    Ref: 3D-PP40193

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  • Acetyl-Myelin Basic Protein (Human, Porcine, Rat, 1-11)

    CAS:
    The myelin sheath which is located in both the Central Nervous System (CNS) and the Peripheral Nervous System is crucial for neural insulation and the salutatory conduction of nerve impulses. When this myelin sheath is destroyed neurodegeneration and conduction failure occur. This can be observed in demyelinating diseases in the CNS such as: acute disseminated encephalomyelitis and multiple sclerosis and within the PNS: Guillain–Barré syndrome and Charcot–Marie–Tooth disease. Myelin Basic Protein (MBP) from which this product is derived is the second most abundant protein in myelin. It has been found to be an intrinsically disordered protein and depending on the environmental conditions it can change its conformation. It also folds into ⍺-helical structures which allow MBP to bind tightly to lipid bilayer surfaces. MBP also interacts with other proteins, namely cytoskeletal proteins and calmodulin and may be involved in signalling pathways. Although more research needs to be carried out, it is thought that MBP significantly contributes to the pathogenesis of multiple sclerosis. As MBP is an autoantigen it can be recognized and cleaved by autoantibodies and is a substrate for the immunoproteasome. Additional research has found that post-translational modifications of MBP such as the removal of arginine are increased in and may be involved in the pathogenesis of multiple sclerosis. Therefore this protein derived from MBP can be used to mimic Neurodegenerative disease phenotypes in research and animal models.
    Formula:C52H88N22O17
    Purezza:Min. 95%
    Peso molecolare:1,293.42 g/mol

    Ref: 3D-PMB-3658-PI

    1mg
    211,00€
    5mg
    689,00€
  • H-R^PKPQQFFGLM-OH


    Peptide H-R^PKPQQFFGLM-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

    Ref: 3D-PP48069

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  • H-HLTHAQSTLDAK^-OH


    Peptide H-HLTHAQSTLDAK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

    Ref: 3D-PP41967

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  • Leupeptin hemisulphate salt monohydrate (Synthetic)

    CAS:
    Leupeptin is a naturally occurring protease inhibitor that has been synthetically produced for use as an experimental tool. Leupeptin inhibits the activity of basic proteins and enzymes by binding to them at the active site, preventing their access to substrate. This inhibition can be reversed with reducing agents (e.g., dithiothreitol). Leupeptin has been shown to inhibit neuronal death during anoxia in experimental models and has also been shown to have neurotrophic effects, which may be due to its ability to prevent protein aggregation.
    Formula:C20H38N6O4•(H2SO4)0•H2O
    Purezza:Min. 95%
    Peso molecolare:493.61 g/mol

    Ref: 3D-ILP-3851-PI

    25mg
    309,00€
    100mg
    782,00€
  • H-VDTVDPPYPR^-OH


    Peptide H-VDTVDPPYPR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

    Ref: 3D-PP41641

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  • TAT (47-57) TFA salt

    CAS:

    Amino acids 47-57 of the Human Immunodeficiency Virus (HIV) viral coat trans-activator of transcription protein (TAT protein). TAT is a cell penetrating peptide meaning it has the ability to transport itself across cell membranes and into a cell's nucleus independently. Cell penetrating peptides (CPPs) can be used to carry other molecules into the cell and therefore can be used in many applications. Such applications may include: drug delivery, where small drug peptides or nucleic acids can be delivered into target cells or where CPPs are conjugated to imaging agents such as fluorescent dyes or radiolabeled molecules they can be used for in vivo or in vitro imaging in diagnostics. 
    This product is available as a trifluroacetate salt.

    Formula:C64H118N32O14
    Purezza:Min. 95%
    Peso molecolare:1,559.86 g/mol

    Ref: 3D-TAT-3768-PI

    1mg
    205,00€
    5mg
    581,00€
  • MOG 37-50


    Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool

    Ref: 3D-PP50834

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  • 5Azido-AAAYSSGAPPMPPF-OH


    Peptide 5Azido-AAAYSSGAPPMPPF-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

    Ref: 3D-PP43632

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  • H-Ser-Phe-Leu-Leu-Arg-Asn-NH2

    CAS:

    This is a monoclonal antibody that binds to the alpha-integrin receptor. The alpha-integrin receptor is an integrin that is involved in cell adhesion and migration, as well as the activation of several signaling pathways. This antibody has been shown to inhibit the binding of alpha-integrins to phospholipid membranes, which may be due to inhibition of protein kinase C (PKC). This antibody also inhibits thrombin receptor activation and dextran sulfate-induced cytosolic calcium mobilization.

    Formula:C34H57N11O8
    Purezza:Min. 95%
    Peso molecolare:747.9 g/mol

    Ref: 3D-PAR-3676-PI

    1mg
    136,00€
    5mg
    370,00€
  • H-A^^P^^G^^-OH


    Peptide H-A^^P^^G^^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

    Ref: 3D-PP49290

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  • Ac-CDGLKFDLGTPL-NH2


    Peptide Ac-CDGLKFDLGTPL-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

    Ref: 3D-PP43866

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  • Ac-PAVLQSSGLYSLSSVVTVPSSSLGTQ-NH2


    Peptide Ac-PAVLQSSGLYSLSSVVTVPSSSLGTQ-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

    Ref: 3D-PP43860

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  • H-RP^PGF-OH


    Peptide H-RP^PGF-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

    Ref: 3D-PP47865

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  • Recombinant Human Parathyroid Hormone aa7-84/Nitrogen-15

    CAS:
    Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool
    Formula:C381H629N119O115S2
    Peso molecolare:8,781.05 g/mol

    Ref: 3D-PP50429

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  • H-QVLQVTPFAER^-OH


    Peptide H-QVLQVTPFAER^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

    Ref: 3D-PP47174

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  • HXB2 gag NO-121/aa481 - 495


    Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool
    Peso molecolare:1,738 g/mol

    Ref: 3D-PP50323

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  • H-TLNAWVK^-OH


    Peptide H-TLNAWVK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

    Ref: 3D-PP41747

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  • H-GPGPGGPGGAGVAR^-OH


    Peptide H-GPGPGGPGGAGVAR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

    Ref: 3D-PP42365

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  • CMVpp65 - 15 (LVSQYTPDSTPCHRG)


    Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool
    Peso molecolare:1,660.8 g/mol

    Ref: 3D-PP50940

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  • Insulin (Human)

    CAS:

    Insulin is a peptide hormone that regulates the uptake and storage of glucose by muscle and fat cells. Insulin is produced by beta cells in the pancreas, which release it into the bloodstream when blood sugar levels rise. Insulin lowers glucose levels by increasing the amount of glucose taken up from the blood into muscle and fat cells, suppressing hepatic gluconeogenesis, and promoting glycolysis. It also increases protein synthesis, decreases proteolysis, and stimulates growth. With a molecular weight of 5808 Da, insulin is composed of two polypeptide chains with an approximate molecular weight of 3120 Da each linked by disulfide bonds. Insulin has no lipid moiety or carbohydrate moiety.
    Insulin binds to its receptor on the surface of a cell to trigger one or more signaling cascades leading to changes in metabolism. Binding to the receptor triggers a conformational change in the receptor that causes insulin to be released from its binding site on the receptor.

    Formula:C257H383N65O77S6
    Purezza:Min. 95%
    Peso molecolare:5,807.6 g/mol

    Ref: 3D-PIN-4088-S

    100µg
    657,00€
  • H-VTQSNFAVGYK^-OH


    Peptide H-VTQSNFAVGYK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

    Ref: 3D-PP40803

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  • H-L^QSLFDSP^DFSK^-OH


    Peptide H-L^QSLFDSP^DFSK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

    Ref: 3D-PP45295

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  • H-PIIHFGSDYEDR^-OH


    Peptide H-PIIHFGSDYEDR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

    Ref: 3D-PP42081

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  • Cpp-AAF-pAb

    CAS:
    Cpp-AAF-pAb is a synthetic peptide that corresponds to the amino acid sequence of the C terminus of human basic fibroblast growth factor (bFGF) and has been shown to have a variety of effects on cells. It has been used in cell culture studies to measure the effect of bFGF on renal blood flow, which is an important marker for kidney disease. In addition, this peptide inhibits tumor cell growth and has antinociceptive properties in rats. The inhibition of tumor cell growth may be due to its ability to inhibit metalloendopeptidases and polyclonal antibodies.
    Formula:C32H36N4O7
    Purezza:Min. 95%
    Peso molecolare:588.67 g/mol

    Ref: 3D-IAP-3754-PI

    1mg
    232,00€
    5mg
    730,00€
  • H-VYTVDLGR^-OH


    Peptide H-VYTVDLGR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

    Ref: 3D-PP40321

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  • Ac-RLIEDICLPRWGCLWEDD-NH2


    Peptide Ac-RLIEDICLPRWGCLWEDD-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

    Ref: 3D-PP43386

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  • H-IQAEPDNLAR^-OH


    Peptide H-IQAEPDNLAR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

    Ref: 3D-PP41533

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  • H-AVTSANIQEFAGCK^-OH


    Peptide H-AVTSANIQEFAGCK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

    Ref: 3D-PP47945

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  • H-TIVGALIQSVK^-OH


    Peptide H-TIVGALIQSVK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

    Ref: 3D-PP42445

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  • CMVpp65 - 29 (VYALPLKMLNIPSIN)


    Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool
    Peso molecolare:1,686.1 g/mol

    Ref: 3D-PP51024

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  • MOG (Rat, Mouse, 35-55)

    CAS:
    Amino acids 35-55 derived from the Immunogenic Myelin Oligodendrocyte protein (MOG). Produced by oligodendrocytes, MOG is an integral part of the oligodendrocyte surface membrane, located in the central nervous system (CNS) and plays an important role in the maintenance and disintegration of the myelin sheath. Unique within their immunoglobulin superfamily, MOG is composed of a transmembrane hydrophobic domain, an extracellular immunoglobulin variable (IgV) domain, a short cytoplasmic loop and within the membrane bilayer there is a second hydrophobic region and after this, a cytoplasmic end. In addition to 218 amino acids of the mature MOG protein, it contains a 29 amino acids long signal peptide. MOG has not only been found to be expressed in the CNS but also at low levels in the peripheral nervous system. Generally MOG is expressed during myelination and functions to maintain the myelin sheath’s structurally integrity through mediating interactions between the myelin and the immune system. This is possible due to its adhesion characteristics and its external location which makes it accessible to antibodies and T-cells. Furthermore is has been suggested that MOG is involved in regulating oligodendrocyte microtubule stability and it can be used as a differentiation marker for oligodendrocyte maturation.Myelin forms a lipid layer around neurons which insulates them. MOG has immunodmainant epitopes: 1-22; 35-55 and 92-106 and this is located at the dimer interface which is formed by MOG IgV domains forming a dimer. These MOG epitopes are recognized by encepalitogenic T cells as foreign antigens. As a result demyelination occurs and this happens in the disease state of Multiple Sclerosis (MS). As MOG is associated with inflammatory demyelinating diseases within the CNS such as neuromyelitis optica spectrum disorders and acute disseminated encephalomyelitis, this MOG (35-55) product can be used to induce these disease states in animal models. One-Letter Formula: MEVGWYRSPFSRVVHLYRNGK
    Formula:C118H177N35O29S
    Purezza:Min. 95%
    Peso molecolare:2,581.95 g/mol

    Ref: 3D-PMG-3660-PI

    1mg
    275,00€
    5mg
    859,00€
  • H-GTYLTDETHR^-OH


    Peptide H-GTYLTDETHR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

    Ref: 3D-PP41049

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  • H-SYPSNATCPR^-OH


    Peptide H-SYPSNATCPR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

    Ref: 3D-PP49826

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  • H-WQEEMELYR^-OH


    Peptide H-WQEEMELYR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

    Ref: 3D-PP46162

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  • H-DVNAAIAAIK^-OH


    Peptide H-DVNAAIAAIK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

    Ref: 3D-PP42643

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  • H-LDVDQALNR^-OH


    Peptide H-LDVDQALNR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

    Ref: 3D-PP42663

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  • Myelin Basic Protein (87-99)

    CAS:

    The myelin sheath which is located in both the Central Nervous System (CNS) and the Peripheral Nervous System is crucial for neural insulation and the salutatory conduction of nerve impulses. When this myelin sheath is destroyed neurodegeneration and conduction failure occur. This can be observed in demyelinating diseases in the CNS such as: acute disseminated encephalomyelitis and multiple sclerosis and within the PNS: Guillain–Barré syndrome and Charcot–Marie–Tooth disease.
    Myelin Basic Protein (MBP) from which this product is derived is the second most abundant protein in myelin. It has been found to be an intrinsically disordered protein and depending on the environmental conditions it can change its conformation. It also folds into ⍺-helical structures which allow MBP to bind tightly to lipid bilayer surfaces. MBP also interacts with other proteins, namely cytoskeletal proteins and calmodulin and may be involved in signalling pathways.
    Although more research needs to be carried out, it is thought that MBP significantly contributes to the pathogenesis of multiple sclerosis. As MBP is an autoantigen it can be recognized and cleaved by autoantibodies and is a substrate for the immunoproteasome. Additional research has found that post-translational modifications of MBP such as the removal of arginine are increased in and may be involved in the pathogenesis of multiple sclerosis. Therefore this protein derived from MBP can be used to mimic Neurodegenerative disease phenotypes in research and animal models.

    Formula:C74H114N20O17
    Purezza:Min. 95%
    Peso molecolare:1,555.86 g/mol

    Ref: 3D-PMB-3973-PI

    1mg
    275,00€
    5mg
    859,00€
  • HLA leader peptide LIL


    Peptide H-VMAPRTLIL-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

    Ref: 3D-PP44080

    1mg
    226,00€
    10mg
    263,00€
    100mg
    473,00€
  • HXB2 gag NO-79/aa313 - 327


    Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool
    Peso molecolare:1,761 g/mol

    Ref: 3D-PP50204

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  • H-LPLAYPQWYYANSEEWTFPTE-NH2


    Peptide H-LPLAYPQWYYANSEEWTFPTE-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

    Ref: 3D-PP44662

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  • H-RTVAAPSVFIFPPSDEQLK^-OH


    Peptide H-RTVAAPSVFIFPPSDEQLK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

    Ref: 3D-PP40479

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  • H-TEAFIPFSLGK^-OH


    Peptide H-TEAFIPFSLGK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

    Ref: 3D-PP42820

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  • Ac-KFKFKFKF-NH2


    Peptide Ac-KFKFKFKF-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

    Ref: 3D-PP42737

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  • Biot-GRADSP-NH2


    Peptide Biot-GRADSP-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

    Ref: 3D-PP45043

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  • H-FLLTR^ILTI^-OH


    Peptide H-FLLTR^ILTI^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

    Ref: 3D-PP41799

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  • Suc-Phe-Ala-Ala-Phe-pNA

    CAS:

    Suc-Phe-Ala-Ala-Phe-pNA is an amino acid that is a substrate for the serine protease myroilysin. It is used in biochemical research to investigate the physiological function of myroilysin. Suc-Phe-Ala-Ala-Phe-pNA has been shown to be an irreversible inhibitor of myroilysin and inhibits enzyme catalysis.

    Formula:C34H38N6O9
    Purezza:Min. 95%
    Peso molecolare:674.70 g/mol

    Ref: 3D-SUB-3007-PI

    25mg
    157,00€
    50mg
    206,00€
    200mg
    502,00€
  • HIV - 1 MN ENV - 170


    Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool
    Peso molecolare:1,897.4 g/mol

    Ref: 3D-PP51008

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  • Activity-Dependent Neurotrophic Factor, ADNF


    Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool
    Formula:C41H74N12O12
    Peso molecolare:927.12 g/mol

    Ref: 3D-PP50230

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  • Pal-RWKFGGFKWR-OH


    Peptide Pal-RWKFGGFKWR-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

    Ref: 3D-PP49511

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  • H-AAAHVVEGAAGYAGHK^-OH


    Peptide H-AAAHVVEGAAGYAGHK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

    Ref: 3D-PP40909

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  • H-DMQL^G-OH


    Peptide H-DMQL^G-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

    Ref: 3D-PP40143

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  • H-NDGYLMFQQVPMVEIDGMK^-OH


    Peptide H-NDGYLMFQQVPMVEIDGMK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

    Ref: 3D-PP42247

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  • H-Gly-Pro-Arg-Pro-OH

    Prodotto controllato
    CAS:
    H-Gly-Pro-Arg-Pro-OH is a sealant that has been shown to be effective in the treatment of bowel disease. It is a calcium binding compound that can be administered topically or systemically. H-Gly-Pro-Arg-Pro-OH has clinical relevance in vivo with human beings and exhibits ATP levels that are similar to those found in normal tissue. The surface glycoprotein of this compound has been shown to have an affinity for epidermal growth factor, which may play a role in inflammatory bowel disease. HGPAROH is activated by fibrinogen, which leads to its bound form being recognized by monoclonal antibody as well as the human serum proteins (e.g., albumin).
    Formula:C18H31N7O5
    Purezza:Min. 95%
    Peso molecolare:425.48 g/mol

    Ref: 3D-INH-3797-PI

    5mg
    136,00€
    25mg
    287,00€
  • H-CLAVEEVSL^-OH


    Peptide H-CLAVEEVSL^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

    Ref: 3D-PP48447

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  • H-GAGSSQHQER^-OH


    Peptide H-GAGSSQHQER^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

    Ref: 3D-PP42543

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  • H-GFYPSDIAVEWESNGQPENNYK-OH


    Peptide H-GFYPSDIAVEWESNGQPENNYK-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

    Ref: 3D-PP42776

    1mg
    408,00€
    10mg
    495,00€
    100mg
    882,00€
  • H-DSHSLTTNIMEILR^-OH


    Peptide H-DSHSLTTNIMEILR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

    Ref: 3D-PP42103

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  • H-CGERGFFYTPMS-NH2


    Peptide H-CGERGFFYTPMS-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

    Ref: 3D-PP44554

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  • H-VNTLTER^-OH


    Peptide H-VNTLTER^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

    Ref: 3D-PP49087

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  • H-DGQLTIK^-OH


    Peptide H-DGQLTIK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

    Ref: 3D-PP41849

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    Prezzo su richiesta
  • PAR-2 (1-6) (mouse, rat)

    CAS:

    Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool

    Formula:C29H56N10O7
    Peso molecolare:656.83 g/mol

    Ref: 3D-PP50110

    ne
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  • [Cys9] - β - Amyloid (1 - 9)


    Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool
    Peso molecolare:1,079.1 g/mol

    Ref: 3D-PP50229

    ne
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  • Hepcidin-22 (Human)

    CAS:

    Hepcidin product containing the disulfide Bonds: Cys4-Cys20, Cys7-Cys10, Cys8-Cys16, and Cys11-Cys19 and available in the trifluoroacetate salt form. Hepcidin-22 is a variant of the peptide hormone hepcidin-25, which plays an important role in the regulation of iron metabolism in the body. Hepcidin is produced by the liver and is secreted into the bloodstream.
    Hepcidin binds to ferroportin, a protein that facilitates the export of iron from cells into the bloodstream, and to inhibit its activity.
    The biological significance of hepcidin-22 is still being studied, but it may play a role in the regulation of iron metabolism in certain situations, such as inflammation or certain disease states. Both hepcidin-22 and hepcidin-25 are targets for the development of treatments for iron-related disorders, such as anemia of chronic disease and hemochromatosis.

    Formula:C99H151N29O25S9
    Purezza:Min. 95%
    Peso molecolare:2,436.06 g/mol

    Ref: 3D-PLP-3776-PI

    1mg
    1.041,00€
    500µg
    646,00€