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The 6-Fluoro-3-indoxyl-beta-D-galactopyranoside is an effective antituberculosis drug that falls under the class of rifamycins. It is known for its bactericidal activity against tuberculosis infection. By binding to DNA-dependent RNA polymerase, this drug inhibits bacterial growth and prevents transcription and replication. The high frequency of human activity has been demonstrated using a patch-clamp technique on human erythrocytes. Metabolized through various metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid, this drug effectively targets Mycobacterium tuberculosis strains and inhibits cell growth in culture.
Tilmicosin is a macrolide antibiotic widely used in veterinary medicine to treat respiratory disorders caused by bacteria such as Clostridium perfringens. By binding to the