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N-(5-tert-Butyl-1,2-oxazol-3-yl)-2-{4-[5-(1-methyl-1H-pyrazol-4-yl)-1H-1,3-benzodiazol-1-yl]phenyl}acetamide
CAS: 1800505-64-9
Rif. 3D-AXC50564
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Informazioni sul prodotto
N-(5-tert-Butyl-1,2-oxazol-3-yl)-2-[4-(5-(1-methyl-1H-pyrazol-4-yl)-1H-1,3-benzodiazol-1-yl)phenyl]acetamide (TPOXX) is a new potent and broad spectrum antifungal agent with photochemical properties. It has been shown to be active against opportunistic fungal pathogens, such as Candida glabrata and bacterial strains, including Pseudomonas aeruginosa. TPOXX is also effective against Gram positive bacteria, including methicillin resistant Staphylococcus aureus (MRSA). TPOXX inhibits the enzyme DNA polymerase and is a competitive inhibitor of topoisomerase I. The reaction mechanism of TPOXX involves the formation of adducts that are stabilized by hydrogen bonds between the carbonyl group of the
Proprietà chimiche
Richiesta tecnica su: 3D-AXC50564 N-(5-tert-Butyl-1,2-oxazol-3-yl)-2-{4-[5-(1-methyl-1H-pyrazol-4-yl)-1H-1,3-benzodiazol-1-yl]phenyl}acetamide
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