Effusanin B
CAS: 76470-16-1
Rif. 3D-BDA47016
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Informazioni sul prodotto
Effusanin B is a natural product that has been isolated from the plant, Sphaeropteris sphaeroides. This compound is an analytical standard for HPLC and a reference material for the quality control of secondary metabolites. Effusanin B is also used in screening and research and development activities as it has potent antibacterial activity. It is found to inhibit bacterial growth by binding to DNA-dependent RNA polymerase, thereby preventing transcription and replication. The high frequency of human activity has been shown using a patch-clamp technique on human erythrocytes. This active form is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. Effusanin B also specifically binds to markers expressed at high levels in Mycobacterium tuberculosis strains (e.g.,
Proprietà chimiche
Richiesta tecnica su: 3D-BDA47016 Effusanin B
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