LY3177833
CAS: 1627696-51-8
Rif. 3D-CQC69651
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Informazioni sul prodotto
LY3177833 is a protein kinase inhibitor that binds to the ATP-binding pocket of the enzyme, inhibiting its function. LY3177833 has been shown to be effective against colon cancer cells and has been used in clinical trials. The drug was well-tolerated by patients and had no significant side effects. The efficacy of LY3177833 was demonstrated in vitro, where it inhibited the growth of colon cancer cells with an IC50 of 3 nM at 24 hours. LY3177833 also showed anti-tumor effects in a mouse xenograft model, blocking tumor growth and reducing the number of metastases. In addition, LY3177833 inhibits cellular senescence by inhibiting production of β-galactosidase enzymes and the expression of cancer-related genes.
Proprietà chimiche
Richiesta tecnica su: 3D-CQC69651 LY3177833
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