Informazioni sul prodotto
Nome:Biotin-LPETAG N-terminal Sortagging
Sinonimi:
- Biot-LPETAG-NH2
Marchio:Biosynth
Descrizione:This peptide is recognised and cleaved by the enzyme Sortase A (SrtA) from-Staphylococcus aureus. The catalytic cysteine residue in the active site of SrtA, serves as a nucleophile to cleave the peptide bond between threonine and glycine. Cleavage results in the formation of a thioacyl intermediate between the peptide and SrtA. This intermediate is then resolved by the N-terminus of an (oligo)glycine nucleophile, resulting in the creation of a new peptide bond that links the peptide and its biotin tag to the incoming nucleophile.- This method of protein labelling is known as sortagging.This peptide contains an N-terminal biotin tag for detection and purification.
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Proprietà chimiche
Peso molecolare:811.4 g/mol
Colore/Forma:Powder