DAG peptide
Rif. 3D-CRB1000885
| 1mg | 271,00 € | ||
| 500µg | 198,00 € |
Informazioni sul prodotto
- [Cyc(1,9)]H-CDAGRKQKC-OHCDAGRKQKC-acid
- (Disulfide bridge: Cys1 - Cys9)H-Cys-Asp-Ala-Gly-Arg-Lys-Gln-Lys-Cys-OH
- (Disulfide bridge : Cys1 - Cys9)
Cyclic DAG peptide targets connective tissue growth factor (CTGF/CCN2), present in the extracellular matrix, endothelial cells and overexpressed in several brain diseases. CTGF is a matricellular protein that acts as a regulator of several cellular functions, including cell adhesion, migration, mitogenesis, differentiation, and survival. CTGF is up regulated in Alzheimer's disease, Parkinson's disease, brain injury, glioblastoma, and cerebral infarction.DAG peptide has been shown to home to the brain in mouse models of glioblastoma, traumatic brain injury, and Parkinson's disease when exogenously delivered, making it an attractive target for the treatment of glioblastoma. DAG may be of use as a tool to enhance delivery of therapeutics and imaging agents to sites of brain diseases.
Proprietà chimiche
Richiesta tecnica su: 3D-CRB1000885 DAG peptide
Se si desidera richiedere un preventivo o effettuare un ordine, si prega invece di aggiungere i prodotti desiderati al carrello e poi richiedere un preventivo o un ordine dal carrello. È più veloce, più economico, e potrà beneficiare degli sconti disponibili e di altri vantaggi.
