Informazioni sul prodotto
Nome:Biotin-DAG Peptide
Sinonimi:
- [Cyc(1,9)]Biot-CDAGRKQKC-OHBiotin-CDAGRKQKC-acid
- (Disulfide bridge: Cys1 - Cys9)Biotin-Cys-Asp-Ala-Gly-Arg-Lys-Gln-Lys-Cys-OH
- (D isulfide bridge: Cys1 - Cys9 )a-Calcitonin gene-related peptide (mous
Marchio:Biosynth
Descrizione:Cyclic DAG peptide targets connective tissue growth factor (CTGF/CCN2), present in the extracellular matrix, endothelial cells and overexpressed in several brain diseases. CTGF is a matricellular protein that acts as a regulator of several cellular functions, including cell adhesion, migration, mitogenesis, differentiation, and survival. CTGF is up regulated in Alzheimer's disease, Parkinson's disease, brain injury, glioblastoma, and cerebral infarction.DAG peptide has been shown to home to the brain in mouse models of glioblastoma, traumatic brain injury, and Parkinson's disease when exogenously delivered, making it an attractive target for the treatment of glioblastoma. DAG may be of use as a tool to enhance delivery of therapeutics and imaging agents to sites of brain diseases.
Avviso:I nostri prodotti sono destinati esclusivamente ad uso di laboratorio. Per qualsiasi altro utilizzo, vi preghiamo di contattarci.
Proprietà chimiche
Peso molecolare:1,231.5 g/mol