![nef protein fragment (Acetyl/amide) [Human immunodeficiency virus 1]](https://static.cymitquimica.com/products/3D/img/CRB1001225.png "Cliccare per ingrandire")
nef protein fragment (Acetyl/amide) [Human immunodeficiency virus 1]
Rif. 3D-CRB1001225
| 1mg | 271,00 € | ||
| 500µg | 198,00 € |
Informazioni sul prodotto
- Ac-KGENTSLLHP-NH2
Nef is an accessory protein highly conserved amongst all primate lentiviruses, it is essential for viral replication in vivo- it is expressed by human immunodeficiency virus (HIV) HIV-1 and HIV-2. Nef acts as a downregulator of class I human leukocyte antigens (HLA) expression in HIV-infected cells to help circumvent the immune response, such as Cytotoxic T lymphocytes (CTL) activity. An intact nef gene is critical for high viral loads, linked to development of acquired immunodeficiency syndrome (AIDS). Certain alleles of HLA have been associated with maintaining a seronegative status such as HLA-A*1101.This nef peptide sequence contains the region considered to be a a C-proximal adaptor-protein (AP) interaction site. The presence of various nef motifs such as this are an intense area of investigation to understand if they are a factor in patients who remain clinically asymptomatic. This nef fragment is provided with an N-terminal acetyl group to increase its stability.
Proprietà chimiche
Richiesta tecnica su: 3D-CRB1001225 nef protein fragment (Acetyl/amide) [Human immunodeficiency virus 1]
Se si desidera richiedere un preventivo o effettuare un ordine, si prega invece di aggiungere i prodotti desiderati al carrello e poi richiedere un preventivo o un ordine dal carrello. È più veloce, più economico, e potrà beneficiare degli sconti disponibili e di altri vantaggi.
