OVA (323 - 339) amide
Rif. 3D-CRB1001227
| 1mg | 284,00 € | ||
| 500µg | 207,00 € |
Informazioni sul prodotto
- H-ISQAVHAAHAEINEAGR-NH2
Ova (323-339) is an epitope of interest from egg white albumen, which is widely used in allergy research. Ovalbumin is a glycoprotein that is sufficiently large and complex to be mildly immunogenic. It has been demonstrated that ovalbumin contains B-cell epitopes which are recognized by specific IgE antibodies, and CD4 T cell epitopes restricted by the MHC I-Ad molecule in mice and by HLA-D molecule in human.OVA (323-339) can be used to study binding of class II MHC-peptide and T-cell activation in PBMCs by ELISPOT assays. This method quantifies peptide-epitope specificity and IFN-γ releasing effector cells. It has been shown that OVA (323-339) was responsible for 25-35% of T-cell response of isolated BALB/c mouse. An investigation has demonstrated that OVA and OVA (323-339) induced similar lung inflammation and a Th2-like dominant immune response in mouse model.
Proprietà chimiche
Richiesta tecnica su: 3D-CRB1001227 OVA (323 - 339) amide
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