Informazioni sul prodotto
- (4-Methylthien-2-Yl)Methylamine
- (4-Methylthien-2-yl)methanamine
- (4-Methylthiophen-2-yl)methanamine
- 1-(4-Methylthiophen-2-Yl)Methanamine
- 2-(Aminomethyl)-4-Methylthiophene
- 2-(Aminomethyl)-4-methylthiophene 97%
- 2-Thiophenemethanamine, 4-methyl-
- 4-Methyl-2-(Aminomethyl)Thiophene
- 4-Methyl-2-thiophenemethanamine
(4-Methyl-2-thienyl)methylamine is an inhibitor of protein kinases, which are enzymes that phosphorylate other proteins. It has been shown to have a high affinity for the dyrk1a protein and selectivity for this kinase over others. (4-Methyl-2-thienyl)methylamine also inhibits dyrk1a with a potency similar to that of ATP. The analogue of (4-methyl-2-thienyl)methylamine is more potent than the parent molecule at inhibiting dyrk1a. Docking studies show that (4-methyl-2-thienyl)methylamine binds in the active site of dyrk1a and prevents it from phosphorylating its substrate, leading to inhibition of cell growth in culture.
Proprietà chimiche
Richiesta tecnica su: 3D-EEA16339 (4-Methyl-2-thienyl)methylamine
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