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4-Azaspiro[2.4]heptan-5-one is a cyclopropanation reagent that is used in the synthesis of azaspirocycles and other biologically active compounds. It is typically synthesized from an isopropoxide or a titanium compound and various organometallic reagents, such as Grignard reagents or nitriles. The exact mechanism of action of this molecule has not been fully elucidated, but it likely involves a nucleophilic attack on the carbonyl group followed by elimination of carbon dioxide. 4-Azaspiro[2.4]heptan-5-one has been shown to react with cyanoesters to form azaspirocycles, which are important pharmacophores for developing new drugs.