AG 120

CAS: 1448347-49-6

Rif. 3D-FA145491

Informazioni sul prodotto

• Nome: AG 120
• Sinonimi: Ivosidenib
• Marchio: Biosynth
• Descrizione: Inhibits isocitrate dehydrogenase 1 (IDH-1) harbouring a gain of function mutation at R132, which causes impaired cellular differentiation via epigenetic modulation. By inhibiting mutant IDH1, synthesis of oncometabolite 2-hydroxyglutarate is reduced. This compound therefore has therapeutic potential in solid and haematological malignancies, such as acute myeloid leukemia (AML).

Proprietà chimiche

• Peso molecolare: 582.96 g/mol
• Formula: C₂₈H₂₂ClF₃N₆O₃
• Purezza: Min. 95%
• Colore/Forma: White To Off-White Solid