2-Aminopyridine-3-boronic acid pinacol ester

CAS: 1073354-97-8

Rif. 3D-FA159888

Informazioni sul prodotto

• Nome: 2-Aminopyridine-3-boronic acid pinacol ester
• Sinonimi: 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-pyridinamine, 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-amine, 2-Pyridinamine, 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-, [3-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)pyridin-2-yl]amine

Descrizione

2-Aminopyridine-3-boronic acid pinacol ester is a nicotinamide analogue that has been investigated as a potential anticancer drug. This compound was found to be effective in inhibiting the growth of colon cancer cells and mouse tumor cells, with significant effects on cell cycle progression. 2-Aminopyridine-3-boronic acid pinacol ester inhibits the mutant isoforms of the enzyme protein kinase C (PKC) by binding to its catalytic domain. PKC is involved in the regulation of cell division, so this inhibition may have anticancer effects.

• Marchio: Biosynth

Proprietà chimiche

• Peso molecolare: 220.08 g/mol
• Formula: C₁₁H₁₇BN₂O₂
• Purezza: Min. 95%
• InChI: InChI=1S/C11H17BN2O2/c1-10(2)11(3,4)16-12(15-10)8-6-5-7-14-9(8)13/h5-7H,1-4H3,(H2,13,14)
• InChI key: InChIKey=FSJAKASJCJZKET-UHFFFAOYSA-N
• SMILES: CC1(C)OB(c2cccnc2N)OC1(C)C