7-Amino nitrazepam
CAS: 4928-02-3
Rif. 3D-FA17373
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Informazioni sul prodotto
- 7-Amino-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-one1,3-Dihydro-7-amino-5-phenyl-2H-1,4-benzodiazepin -2-oneRo-05-3072
- 1,3-Dihydro-7-amino-5-phenyl-2H-1,4-benzodiazepin-2-one
- 2H-1,4-benzodiazepin-2-one, 7-amino-1,3-dihydro-5-phenyl-
- 7-Amino-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-one
- 7-Aminonitrazepam
- Ro 05-3072
7-Amino nitrazepam is a metabolite of the benzodiazepine drug flunitrazepam. It is formed in the liver by cytochrome P450 and excreted in the urine. 7-Amino nitrazepam has been shown to have inhibitory effects on human liver and human serum. The inhibitory activity was found to be more potent than that of flunitrazepam, but less potent than that of alprazolam. 7-Amino nitrazepam was also found to inhibit rat liver microsomes, which could lead to a higher potency in vivo. This study also showed that 7-Amino nitrazepam is absorbed from the gastrointestinal tract and distributed into all tissues, including the brain, and can be detected in blood serum and urine samples.
Proprietà chimiche
Richiesta tecnica su: 3D-FA17373 7-Amino nitrazepam
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