N-(2-Aminoethyl)-5-chloroisoquinoline-8-sulfonamide

CAS: 120615-25-0

Rif. 3D-FA17736

Informazioni sul prodotto

• Nome: N-(2-Aminoethyl)-5-chloroisoquinoline-8-sulfonamide
• Sinonimi: N-(2-Aminoethyl)-5-chloro-8-isoquinolinesulfonamideCKI-7, 8-Isoquinolinesulfonamide, N-(2-aminoethyl)-5-chloro-, 8-Isoquinolinesulfonamide, N-(2-aminoethyl)-5-chloro- Dihydrochloride, N-(2-Aminoethyl)-5-chloro-8-isoquinolinesulfonamide, N-(2-aminoethyl)-5-chloroisoquinoline-8-sulfonamide
• CAS: 120615-25-0

Descrizione

N-(2-Aminoethyl)-5-chloroisoquinoline-8-sulfonamide is a natural compound that has been shown to inhibit the enzyme secretase, which plays an important role in the development of cancer. The drug may also act as a signal pathway inhibitor by inhibiting the activity of phosphatidylinositol 3 kinase and protein kinase C (PKC). N-(2-Aminoethyl)-5-chloroisoquinoline-8-sulfonamide also inhibits the production of glutamate, a neurotransmitter, by blocking calcium channels in neurons. This drug has been shown to increase bone mass and decrease bone resorption in rats with bone cancer. It is also effective against solid tumours such as breast, lung, and prostate cancers. N-(2-Aminoethyl)-5-chloroisoquinoline-8-sulfonamide is structurally related to other drugs used for platinum based chemotherapy.

• Marchio: Biosynth

Proprietà chimiche

• Peso molecolare: 285.75 g/mol
• Formula: C₁₁H₁₂ClN₃O₂S
• Purezza: Min. 95%
• Colore/Forma: White Powder
• InChI: InChI=1S/C11H12ClN3O2S/c12-10-1-2-11(18(16,17)15-6-4-13)9-7-14-5-3-8(9)10/h1-3,5,7,15H,4,6,13H2
• InChI key: InChIKey=OGKYMFFYOWUTKV-UHFFFAOYSA-N
• SMILES: NCCNS(=O)(=O)c1ccc(Cl)c2ccncc12