5-(2-Amino-4-chloro-5-sulfamoylphenyl)-1H-tetrazole

CAS: 82212-14-4

Rif. 3D-FA75819

Informazioni sul prodotto

• Nome: 5-(2-Amino-4-chloro-5-sulfamoylphenyl)-1H-tetrazole
• Sinonimi: 4-Amino-2-chloro-5-(1H-tetrazol-5-yl)benzenesulfonamide, 4-amino-2-chloro-5-(2H-tetrazol-5-yl)benzenesulfonamide, 5-(4'-Chloro-5'-Sulfamoyl-2'-Amino)Phenyl-Tetrazole, Benzenesulfonamide, 4-amino-2-chloro-5-(1H-tetrazol-5-yl)-, Benzenesulfonamide, 4-amino-2-chloro-5-(2H-tetrazol-5-yl)-

Descrizione

5-(2-Amino-4-chloro-5-sulfamoylphenyl)-1H-tetrazole is a mutant of the drug 5-(2-Amino-4,6dichlorophenyl)-1H-tetrazole which has been metabolized to an inactive form. It is excreted in the urine and has shown sensitivity to potassium. The drug's cytochrome P450 1A2 (CYP1A2) activity has been analyzed and found to be sensitive to inhibition by chlofenuron, sulindac, and diclofenac. This drug also has diuretic effects that are due to its ability to increase chloride reabsorption in the kidney tubule. 5-(2-Amino-4,6dichlorophenyl)-1H-tetrazole is not renally excreted because it does not have any renal clearance pathways.

• Marchio: Biosynth

Proprietà chimiche

• Peso molecolare: 274.69 g/mol
• Formula: C₇H₇ClN₆O₂S
• Purezza: Min. 95%
• InChI: InChI=1S/C7H7ClN6O2S/c8-4-2-5(9)3(7-11-13-14-12-7)1-6(4)17(10,15)16/h1-2H,9H2,(H2,10,15,16)(H,11,12,13,14)
• InChI key: InChIKey=OKHJHVJXPHYALI-UHFFFAOYSA-N
• SMILES: Nc1cc(Cl)c(S(N)(=O)=O)cc1-c1nn[nH]n1