2-[3,5-Bis(Trifluoromethyl)Phenyl]-N,2-Dimethyl-N-[4-(2-Methylphenyl)-6-Morpholin-4-Yl-Pyridin-3-Yl]Propanamide

CAS: 290296-68-3

Rif. 3D-FB103034

Informazioni sul prodotto

• Nome: 2-[3,5-Bis(Trifluoromethyl)Phenyl]-N,2-Dimethyl-N-[4-(2-Methylphenyl)-6-Morpholin-4-Yl-Pyridin-3-Yl]Propanamide
• Sinonimi: 2-(3,5-bis(trifluoromethyl)phenyl)-N-(4-(2-methylphenyl)-6-(morpholin-4-yl)pyridin-3-yl)-N-methylisobutyramide, 2-[3,5-bis(trifluoromethyl)phenyl]-N,2-dimethyl-N-[4-(2-methylphenyl)-6-(morpholin-4-yl)pyridin-3-yl]propanamide, benzeneacetamide, N,alpha,alpha-trimethyl-N-[4-(2-methylphenyl)-6-(4-morpholinyl)-3-pyridinyl]-3,5-bis(trifluoromethyl)-, T6N Dotj A- Bt6Nj Dr B1& En1& Vx1& 1& R Cxfff Exfff [Wln]

Descrizione

2-[3,5-Bis(trifluoromethyl)phenyl]-N,2-dimethyl-N-[4-(2-methylphenyl)-6-morpholin-4-ylpyridin-3-yl]propanamide is a serotonin receptor antagonist that blocks the binding of serotonin to its receptors. It is used in the treatment of chronic cough and emetogenic chemotherapy. Netupitant is also an antagonist of the NK1 receptor and is used in combination with other antiemetics for cancer patients receiving high doses of emetogenic chemotherapy. Netupitant has been shown to have an antidepressant effect, which may be due to its ability to inhibit the release of serotonin from platelets. Netupitant may also cause some side effects such as nausea, vomiting, diarrhea, constipation, or headache. These side effects are usually temporary and can be minimized by taking the drug with food or milk.

• Marchio: Biosynth

Proprietà chimiche

• Peso molecolare: 565.55 g/mol
• Formula: C₂₉H₂₉F₆N₃O₂
• Purezza: Min. 95%
• InChI: InChI=1S/C29H29F6N3O2/c1-18-7-5-6-8-22(18)23-16-25(38-9-11-40-12-10-38)36-17-24(23)37(4)26(39)27(2,3)19-13-20(28(30,31)32)15-21(14-19)29(33,34)35/h5-8,13-17H,9-12H2,1-4H3
• InChI key: InChIKey=ZGNPLCMMVKCTHM-UHFFFAOYSA-N
• SMILES: Cc1ccccc1-c1cc(N2CCOCC2)ncc1N(C)C(=O)C(C)(C)c1cc(C(F)(F)F)cc(C(F)(F)F)c1