5-Bromoindolyl-1,3-diacetate

CAS: 33588-54-4

Rif. 3D-FB11449

Informazioni sul prodotto

• Nome: 5-Bromoindolyl-1,3-diacetate
• Sinonimi: (1-Acetyl-5-bromoindol-3-yl) acetate, 1-Acetyl-5-bromoindol-3-ol acetate, 1-[3-(Acetyloxy)-5-bromo-1H-indol-1-yl]ethanone, 1-acetyl-5-bromo-1H-indol-3-yl acetate, 1H-Indol-3-ol, 1-acetyl-5-bromo-, acetate (ester), 3-Acetoxy-1-acetyl-5-bromoindole, Ethanone, 1-[3-(acetyloxy)-5-bromo-1H-indol-1-yl]-, Indol-3-ol, 1-acetyl-5-bromo-, acetate (ester), Indoxyl, 1-acetyl-5-bromo-, acetate, N-acetyl-5-bromoindolyl acetate

Descrizione

5-Bromoindolyl-1,3-diacetate is an indoxyl that has been optimised for use as a radiation sensitizer. It is a molecule that intercalates into DNA and reacts with the acid molecules in the DNA to form adducts that are resistant to repair by enzymes. The reaction time of 5-bromoindolyl-1,3-diacetate is dependent on the dose administered. This molecule has shown potent inhibition against animal cells in vitro, with a dose dependent response. 5-Bromoindolyl-1,3-diacetate has been used as a tool to study the mechanism of dna damage induced by ionizing radiation in animals.

• Marchio: Biosynth

Proprietà chimiche

• Peso molecolare: 296.12 g/mol
• Formula: C₁₂H₁₀BrNO₃
• Purezza: Min. 95%
• Colore/Forma: Powder
• InChI: InChI=1S/C12H10BrNO3/c1-7(15)14-6-12(17-8(2)16)10-5-9(13)3-4-11(10)14/h3-6H,1-2H3
• InChI key: InChIKey=XJRIDJAGAYGJCK-UHFFFAOYSA-N
• SMILES: CC(=O)Oc1cn(C(C)=O)c2ccc(Br)cc12