N-(1,3-Benzodioxol-5-ylmethyl)-4-benzofuro[3,2-d]pyrimidin-4-yl-1-piperazinecarbothioamide

CAS: 850879-09-3

Rif. 3D-FB151469

Informazioni sul prodotto

• Nome: N-(1,3-Benzodioxol-5-ylmethyl)-4-benzofuro[3,2-d]pyrimidin-4-yl-1-piperazinecarbothioamide
• Sinonimi: Mp 470, Amuvatinib

Descrizione

N-(1,3-Benzodioxol-5-ylmethyl)-4-benzofuro[3,2-d]pyrimidin-4-yl-1-piperazinecarbothioamide is a potent inhibitor of the protein kinase of the BCR/ABL family. It has been shown to inhibit cell proliferation and induce cell death in human myeloma cells. This drug has also been shown to inhibit the activity of toll-like receptor 4 involved in immune function and control of cancer by suppressing the expression of genes related to inflammation. N-(1,3-Benzodioxol-5-ylmethyl)-4-benzofuro[3,2-d]pyrimidin-4-yl piperazinecarbothioamide also inhibits the growth of bacteria that are resistant to antibiotics and prevents infection caused by viruses.

• Marchio: Biosynth

Proprietà chimiche

• Peso molecolare: 447.51 g/mol
• Formula: C₂₃H₂₁N₅O₃S
• Purezza: Min. 95%
• InChI: InChI=1S/C23H21N5O3S/c32-23(24-12-15-5-6-18-19(11-15)30-14-29-18)28-9-7-27(8-10-28)22-21-20(25-13-26-22)16-3-1-2-4-17(16)31-21/h1-6,11,13H,7-10,12,14H2,(H,24,32)
• InChI key: InChIKey=FOFDIMHVKGYHRU-UHFFFAOYSA-N
• SMILES: S=C(NCc1ccc2c(c1)OCO2)N1CCN(c2ncnc3c2oc2ccccc23)CC1