N-[3-(2,1,3-Benzothiadiazol-5-ylamino)-2-quinoxalinyl]-4-methylbenzenesulfonamide,

CAS: 956958-53-5

Rif. 3D-FB18226

Informazioni sul prodotto

• Nome: N-[3-(2,1,3-Benzothiadiazol-5-ylamino)-2-quinoxalinyl]-4-methylbenzenesulfonamide,
• Sinonimi: SC, N-[3-(2,1,3-Benzothiadiazol-5-ylamino)-2-quinoxalinyl]-4-methylbenzenesulfonamide, Pilaralisib, Xl-147, 3-Fluoro-5-formylbenzonitrile, 3-Cyano-5-fluorobenzaldehyde, N-(3-(benzo[c][1,2,5]thiadiazol-5-ylamino)quinoxalin-2-yl)-4-methylbenzenesulfonamide, Benzonitrile, 3-fluoro-5-formyl-, Xl147, Sar245408

Descrizione

N-[3-(2,1,3-Benzothiadiazol-5-ylamino)-2-quinoxalinyl]-4-methylbenzenesulfonamide is a drug that inhibits the activity of cyclin-dependent kinases CDK4/6 and is used to treat bowel diseases, autoimmune diseases, cancer, and HIV infection. It inhibits the growth of hematopoietic cells by binding to toll-like receptors on the cell surface. This drug also has an anti-inflammatory effect through inhibiting inflammatory cytokines such as TNFα and IL-1β. N-[3-(2,1,3-Benzothiadiazol-5-ylamino)-2-quinoxalinyl]-4-methylbenzenesulfonamide binds to epidermal growth factor (EGF) and may have some effects on skin cells.

• Marchio: Biosynth

Proprietà chimiche

• Peso molecolare: 448.52 g/mol
• Formula: C₂₁H₁₆N₆O₂S₂
• Purezza: Min. 95%
• InChI: InChI=1S/C21H16N6O2S2/c1-13-6-9-15(10-7-13)31(28,29)27-21-20(23-16-4-2-3-5-17(16)24-21)22-14-8-11-18-19(12-14)26-30-25-18/h2-12H,1H3,(H,22,23)(H,24,27)
• InChI key: InChIKey=MQMKRQLTIWPEDM-UHFFFAOYSA-N
• SMILES: Cc1ccc(S(=O)(=O)Nc2nc3ccccc3nc2Nc2ccc3nsnc3c2)cc1