TDZD 8
CAS: 327036-89-5
Rif. 3D-FB18327
25mg | 184,00 € | ||
50mg | 315,00 € | ||
100mg | 459,00 € | ||
250mg | 777,00 € | ||
500mg | 1.136,00 € |
Informazioni sul prodotto
- GSK-3b inhibitor I4-Benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione
- 1,2,4-Thiadiazolidine-3,5-dione, 2-methyl-4-(phenylmethyl)-
- Tdzd-8
TDZD 8 is a selective, non-ATP competitive inhibitor of the glycogen synthase kinase GSK3β. TDZD 8 inhibits GSK3β with IC50 of 2 μM and was reported to not significantly affect Cdk-1/cyclin B, casein kinase CK-II, protein kinase A and C (PKA, PKC) activities. TDZD 8 was also identified as an inhibitor of the main protease in coronaviruses. In an in vitro study, TDZD 8 was characterised as an aggregate-based inhibitor as the presence of Triton-X decreased the inhibitory potency to Mpro protease of the SARS-CoV-2 virus (IC50 without Triton-X: 2.15 μM).
Proprietà chimiche
Richiesta tecnica su: 3D-FB18327 TDZD 8
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