3-(2-Benzimidazolyl)-7-(diethylamino)coumarin

CAS: 27425-55-4

Rif. 3D-FB62136

Informazioni sul prodotto

• Nome: 3-(2-Benzimidazolyl)-7-(diethylamino)coumarin
• Sinonimi: Coumarin 7, 248-451-4, 2H-1-Benzopyran-2-one, 3-(1H-benzimidazol-2-yl)-7-(diethylamino)-, 3-(1H-Benzimidazol-2-yl)-7-(diethylamino)-2H-1-benzopyran-2-one, 3-(1H-Benzimidazol-2-yl)-7-(diethylamino)-2H-chromen-2-one, 3-(Benzimidazol-2-yl)-7-diethylamino-2H-benzopyran-2-one, Coumarin 535, Coumarin, 3-(2-benzimidazolyl)-7-(diethylamino)-, D 820 Savannah Yellow, Day-Glo Savannah Yellow, Disperse Yellow 82, Disperse Yellow 8GFF, Fluorescent Yellow 10G, Fluorescent Yellow 9GF, Kayaset Yellow SF-G, Keystone Fluorescent Yellow 10G, NSC 303254, Oracet Yellow 8GF, Polycron Brilliant Yellow 10GF, Savannah Yellow, Setaron Brilliant Flavine 8GFF, Solvent Yellow 145, Solvent Yellow 185, Sumikaron Brilliant Flavine S 10G, Terasil Brilliant Flavine 8GFF, Terasil Flavine 8GFF, Yellow 8GFF

Descrizione

3-(2-Benzimidazolyl)-7-(Diethylamino)coumarin is a coumarin derivative that is reactive to biological systems. It inhibits the activity of cytochrome P450 3A4 (CYP3A4) and cyclic nucleotide phosphodiesterases (PDEs). It has been shown to be an excellent model system for studying the intramolecular hydrogen bonding interactions of p-hydroxybenzoic acid. 3-(2-Benzimidazolyl)-7-(Diethylamino)coumarin has been used in biochemical studies to investigate the inhibitory properties of coumarin derivatives on human CYP3A4 and PDE activities.

• Marchio: Biosynth

Proprietà chimiche

• Peso molecolare: 333.38 g/mol
• Formula: C₂₀H₁₉N₃O₂
• Purezza: Min. 95%
• InChI: InChI=1S/C20H19N3O2/c1-3-23(4-2)14-10-9-13-11-15(20(24)25-18(13)12-14)19-21-16-7-5-6-8-17(16)22-19/h5-12H,3-4H2,1-2H3,(H,21,22)
• InChI key: InChIKey=GOLORTLGFDVFDW-UHFFFAOYSA-N
• SMILES: CCN(CC)c1ccc2cc(-c3nc4ccccc4[nH]3)c(=O)oc2c1