6-Bromo-N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]quinazolin-4-amine

CAS: 944549-41-1

Rif. 3D-FB99426

Informazioni sul prodotto

• Nome: 6-Bromo-N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]quinazolin-4-amine
• Sinonimi: N-(4-(3-fluorobenzyloxy)-3-chlorophenyl)-6-bromoquinazolin-4-amine

Descrizione

6-Bromo-N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]quinazolin-4-amine is a bifunctional drug that has been shown to be an active drug for the treatment of breast cancer. 6-Bromo-N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]quinazolin-4-amine can be synthesized by catalytic arylation of 3,5,6,7,8,8a,9,10 octahydroquinazolino[2,1b][2]benzothiazole with 2-(trimethylsilyl)ethanol and 4-(trimethylsilyl)phenol in the presence of palladium. The compound has also been shown to have antiinflammatory properties due to its ability to inhibit the production of inflammatory cytokines.

• Marchio: Biosynth

Proprietà chimiche

• Peso molecolare: 458.71 g/mol
• Formula: C₂₁H₁₄BrClFN₃O
• Purezza: Min. 95%
• InChI: InChI=1S/C21H14BrClFN3O/c22-14-4-6-19-17(9-14)21(26-12-25-19)27-16-5-7-20(18(23)10-16)28-11-13-2-1-3-15(24)8-13/h1-10,12H,11H2,(H,25,26,27)
• InChI key: InChIKey=IWJDBOBJWQISKU-UHFFFAOYSA-N
• SMILES: Fc1cccc(COc2ccc(Nc3ncnc4ccc(Br)cc34)cc2Cl)c1