6-Chloro-7-methylpurine
CAS: 5440-17-5
Rif. 3D-FC09543
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Informazioni sul prodotto
- 7H-Purine, 6-chloro-7-methyl-
- 7-Methyl-6-chloropurine
6-Chloro-7-methylpurine is a nucleoside analogue that inhibits the multidrug resistance-associated protein (MRP) and the pumps that are responsible for drug efflux. It is useful in the treatment of multidrug resistant organisms, including bacteria, yeast, and protozoa. 6-Chloro-7-methylpurine has been shown to be effective against MRP1 and MRP2, which are important for maintaining drug levels in cells. This compound also inhibits the uptake of drugs by cells. The uptake of 6-chloropurine by humans may be due to its ability to react with thiolate groups on proteins or endogenous substances such as phospholipids or nucleotides. 6-Chloro-7-methylpurine has been shown to inhibit translation in human brain tissue.
Proprietà chimiche
Richiesta tecnica su: 3D-FC09543 6-Chloro-7-methylpurine
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