[(4-Chlorophenyl)thio]acetic acid
CAS: 3405-88-7
Rif. 3D-FC119419
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Informazioni sul prodotto
- acetic acid
- [(4-chlorophenyl)thio]-
- ((p-Chlorophenyl)thio)acetic acid
- 2-(4-Chlorophenyl)sulfanylacetic acid
- 2-(p-Chlorophenylthio)acetic acid
- 2-[(4-Chlorophenyl)sulfanyl]acetic acid
- 2-[(4-Chlorophenyl)thio]acetic acid
- Acetic acid, ((4-chlorophenyl)thio)-
- Acetic acid, ((p-chlorophenyl)thio)-
- Acetic acid, 2-[(4-chlorophenyl)thio]-
- Vedi altri sinonimi
- Brn 1871569
- Nsc 33051
- S-(p-Chlorophenyl)mercaptoacetic acid
- Sn 4095
- W 2683
- Wr 5994
- [(4-Chlorophenyl)Sulfanyl]Acetate
- [(4-Chlorophenyl)Sulfanyl]Acetic Acid
- p-Chlorophenylmercaptoacetic acid
- 4-06-00-01601 (Beilstein Handbook Reference)
[(4-Chlorophenyl)thio]acetic acid is a compound that exhibits cytostatic and cytotoxic effects. It is an analog of the natural substrate for topoisomerase, which it binds to with high affinity. [(4-Chlorophenyl)thio]acetic acid inhibits the activity of DNA gyrase and topoisomerase IV, leading to cell death by inhibiting the production of proteins vital for cell division. [(4-Chlorophenyl)thio]acetic acid has been shown to be effective against PC-3 cells in vitro and has strong antitumor activity in animals. The anticancer mechanism of this drug is not well understood, but may be due to its ability to induce apoptosis.
Proprietà chimiche
Richiesta tecnica su: 3D-FC119419 [(4-Chlorophenyl)thio]acetic acid
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