[(4-Chlorophenyl)thio]acetic acid

CAS: 3405-88-7

Rif. 3D-FC119419

Informazioni sul prodotto

• Nome: [(4-Chlorophenyl)thio]acetic acid
• Sinonimi: acetic acid, [(4-chlorophenyl)thio]-, ((p-Chlorophenyl)thio)acetic acid, 2-(4-Chlorophenyl)sulfanylacetic acid, 2-(p-Chlorophenylthio)acetic acid, 2-[(4-Chlorophenyl)sulfanyl]acetic acid, 2-[(4-Chlorophenyl)thio]acetic acid, Acetic acid, ((4-chlorophenyl)thio)-, Acetic acid, ((p-chlorophenyl)thio)-, Acetic acid, 2-[(4-chlorophenyl)thio]-, Brn 1871569, Nsc 33051, S-(p-Chlorophenyl)mercaptoacetic acid, Sn 4095, W 2683, Wr 5994, [(4-Chlorophenyl)Sulfanyl]Acetate, [(4-Chlorophenyl)Sulfanyl]Acetic Acid, p-Chlorophenylmercaptoacetic acid
• CAS: 3405-88-7

Descrizione

[(4-Chlorophenyl)thio]acetic acid is a compound that exhibits cytostatic and cytotoxic effects. It is an analog of the natural substrate for topoisomerase, which it binds to with high affinity. [(4-Chlorophenyl)thio]acetic acid inhibits the activity of DNA gyrase and topoisomerase IV, leading to cell death by inhibiting the production of proteins vital for cell division. [(4-Chlorophenyl)thio]acetic acid has been shown to be effective against PC-3 cells in vitro and has strong antitumor activity in animals. The anticancer mechanism of this drug is not well understood, but may be due to its ability to induce apoptosis.

• Marchio: Biosynth

Proprietà chimiche

• Peso molecolare: 202.66 g/mol
• Formula: C₈H₇ClO₂S
• Purezza: Min. 95%
• InChI: InChI=1S/C8H7ClO2S/c9-6-1-3-7(4-2-6)12-5-8(10)11/h1-4H,5H2,(H,10,11)
• InChI key: InChIKey=YPKLXLYGMAWXDO-UHFFFAOYSA-N
• SMILES: O=C(O)CSc1ccc(Cl)cc1