1-Cyclohexyl-1H-pyrazol-5-amine
CAS: 3528-50-5
Rif. 3D-FC121828
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Informazioni sul prodotto
- 1H-pyrazol-5-amine
- 1-cyclohexyl-
1-Cyclohexyl-1H-pyrazol-5-amine is a potent inhibitor of human cytochrome P450 enzymes. It can be used to study the inhibition of these enzymes and their interactions with other compounds. 1-Cyclohexyl-1H-pyrazol-5-amine can also be used to study the binding sites on human cytochrome P450, which are located near the active site. The inhibition of human CYP2D6 by 1-cyclohexyl-1H pyrazol 5 amine has been studied extensively in kinetic studies, and it has been found that this compound does not interact with CYP2D6 at its active site but instead interacts with a phenyl group on the enzyme. This interaction causes a decrease in the affinity of CYP2D6 for substrates such as tyrosine hydroxylase, resulting in an increase in the rate of turnover and metabolism of certain drugs.
Proprietà chimiche
Richiesta tecnica su: 3D-FC121828 1-Cyclohexyl-1H-pyrazol-5-amine
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