N-[4-(Chloromethyl)-1,3-thiazol-2-yl]acetamide
CAS: 7460-59-5
Rif. 3D-FC132048
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Informazioni sul prodotto
- acetamide
- N-[4-(chloromethyl)-2-thiazolyl]-
- Acetamide, N-[4-(chloromethyl)-2-thiazolyl]-
- N-(4-Chloromethyl-thiazol-2-yl)-acetamide
- N-[4-(Chloromethyl)-1,3-thiazol-2-yl]acetamide
N-[4-(Chloromethyl)-1,3-thiazol-2-yl]acetamide is a conjugate of the amino acid glutamate and aminotransferase inhibitor. It has been shown to be active against cancer cells in vitro and in vivo. The mechanism of action is not fully understood, but it has been shown to inhibit the activity of glutamate dehydrogenase by binding to its active site and blocking the enzyme's ability to catalyze the conversion of glutamate into alpha-ketoglutarate. N-[4-(Chloromethyl)-1,3-thiazol-2-yl]acetamide also inhibits glutamine synthetase in the liver and brain, leading to a decrease in intracellular levels of glutamine. This drug may also inhibit glutaminase, which converts glutamate into glutamine.
Proprietà chimiche
Richiesta tecnica su: 3D-FC132048 N-[4-(Chloromethyl)-1,3-thiazol-2-yl]acetamide
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