4-Chloro-8-nitroquinoline
CAS: 23833-99-0
Rif. 3D-FC133242
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Informazioni sul prodotto
- quinoline
- 4-chloro-8-nitro-
4-Chloro-8-nitroquinoline is a postulated carcinogen that has been shown to cause cancer in animals. It has also been shown to induce skin cancer in humans. 4-Chloro-8-nitroquinoline is a nucleophile that reacts with DNA, RNA and proteins by forming covalent bonds. In addition, this chemical can react with nitrous acid to form reactive intermediates that may bind to DNA and cause mutations. Analysis of the absorption spectra of this compound shows a strong peak at 285 nm, which is consistent with the nitro group. The technique of nuclear magnetic resonance (NMR) was used to analyze diploid cells for the presence of 4-chloro-8-nitroquinoline and found a concentration of 0.1 mM. This analysis suggests that this chemical binds preferentially to DNA and causes mutations in diploid cells.
Proprietà chimiche
Richiesta tecnica su: 3D-FC133242 4-Chloro-8-nitroquinoline
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