3-(2-Chlorophenyl)-5-methylisoxazole-4-carbonyl chloride

CAS: 25629-50-9

Rif. 3D-FC20332

Informazioni sul prodotto

• Nome: 3-(2-Chlorophenyl)-5-methylisoxazole-4-carbonyl chloride
• Sinonimi: 3-(2-Chlorophenyl)-5-methyl-4-isoxazolecarbonyl chlorideNSC 81237, 3-(2-Chlorophenyl)-5-methyl-1,2-oxazole-4-carbonyl chloride, 3-(2-Chlorophenyl)-5-methyl-4-isoxazolecarbonyl chloride, 3-(2-Chlorophenyl)-5-methylisoxazol-4-carbonyl chloride, 3-(o-Chlorophenyl)-5-methyl-4-isoxazolecarbonyl chloride, 4-Isoxazolecarbonyl chloride, 3-(2-chlorophenyl)-5-methyl-, 4-Isoxazolecarbonyl chloride, 3-(o-chlorophenyl)-5-methyl-, CMIC Chloride, NSC 81237

Descrizione

3-(2-Chlorophenyl)-5-methylisoxazole-4-carbonyl chloride is a subtilisin inhibitor that has been shown to inhibit the growth of Staphylococcus aureus. Inhibition of the enzyme results in decreased production of heterocyclic amines, which are associated with various cancers. 3-(2-Chlorophenyl)-5-methylisoxazole-4-carbonyl chloride is active against a wide range of Gram positive and Gram negative bacteria. It is also active against Mycobacterium tuberculosis, but not against Mycobacterium avium complex. The pharmacokinetics of 3-(2-Chlorophenyl)-5-methylisoxazole-4-carbonyl chloride have been studied in rats and dogs, which showed that it was rapidly absorbed after oral administration and eliminated mainly through the kidneys.

• Marchio: Biosynth

Proprietà chimiche

• Peso molecolare: 256.08 g/mol
• Formula: C₁₁H₇Cl₂NO₂
• Purezza: Min. 95%
• InChI: InChI=1S/C11H7Cl2NO2/c1-6-9(11(13)15)10(14-16-6)7-4-2-3-5-8(7)12/h2-5H,1H3
• InChI key: InChIKey=BPDBLWKFVXHGFT-UHFFFAOYSA-N
• SMILES: Cc1onc(-c2ccccc2Cl)c1C(=O)Cl