Combretastatin A4 phosphate disodium salt
CAS: 168555-66-6
Rif. 3D-FC20546
2mg | Fuori produzione | ||
5mg | Fuori produzione | ||
10mg | Fuori produzione | ||
25mg | Fuori produzione | ||
50mg | Fuori produzione |
Informazioni sul prodotto
- 2-Methoxy-5-[(1Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenol 1-(dihydrogen phosphate) sodium saltCA 4P
- 2-Methoxy-5-[(1Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenol dihydrogen phosphate disodium salt
- Ca 4Dp
- Ca 4P
- Ca4P
- CombretastatinA4disodiumphosphate(CA4P)
- Fosbretabulin disodium
- Fosbretabulin disodium salt
- Ombretastatin A-4 Phosphate, Disodium Salt
- Phenol, 2-methoxy-5-[(1Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]-, 1-(dihydrogen phosphate), sodium salt (1:2)
- Vedi altri sinonimi
- Phenol, 2-methoxy-5-[(1Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]-, dihydrogen phosphate, disodium salt
- Phenol, 2-methoxy-5-[2-(3,4,5-trimethoxyphenyl)ethenyl]-, dihydrogen phosphate, disodium salt, (Z)-
- Sml1131
- disodium 2-methoxy-5-[(Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenyl phosphate
- Combretastatin A4 disodium phosphate
Combretastatin A4 phosphate disodium salt is a potential anticancer agent that has shown to be effective in the treatment of certain cancers, including breast, prostate and lung cancer. It inhibits tumor growth by blocking the activation of toll-like receptor 4 (TLR4), which is involved in inflammation. Combretastatin A4 phosphate disodium salt also inhibits cytosolic Ca2+ release, which may be due to its ability to inhibit phospholipase C activity. This drug has significant cytotoxicity against various tumor cells, with an IC50 value of 0.1 μM. Combretastatin A4 phosphate disodium salt also specifically binds to combretastatin receptors and inhibits cellular physiology such as receptor activity and protein synthesis.